PA-20-185 - NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) is used for the submission of applications to the following Notices of Special Interest (NOSIs)

Active NOSIs

Title Notice Number Organization Release
Date
Expiration
Date
Activity
Code(s)
Notice of Special Interest (NOSI): Research to Stimulate Development of Diagnostics, Therapeutics, and Vaccines for Herpes Simplex Virus (HSV) NOT-AI-24-028 NIAID Mar 27, 2024 Apr 6, 2027 R21, R41/R42, R43/R44, R03, R01
Notice of Special Interest: Womens Health Research NOT-OD-24-079 ORWH , FIC , NCATS , NCCIH , NCI , NEI , NHGRI , NHLBI , NIA , NIAAA , NIAID , NIAMS , NIBIB , NICHD , NIDA , NIDCD , NIDCR , NIDDK , NIEHS , NIGMS , NIMH , NIMHD , NINDS , NINR , NLM , OAR , OBSSR , ODP , ODS , ODSS , SGMRO Mar 26, 2024 Nov 5, 2027 R15, R01, K01, R16, K08, R21, K43, F31, R43/R44, R41/R42, F30, R03, K23, F32, R34
Notice of Special Interest (NOSI): Development of Imaging Techniques for High Resolution and Functional Scanning of In Vivo Human Sensory and Communication Systems NOT-DC-24-025 NIDCD Mar 22, 2024 May 8, 2027 R01, U01, R43/R44, R41/R42, R21
Notice of Special Interest (NOSI): Inborn Errors of Immunity/Primary Immunodeficiencies NOT-AI-24-024 NIAID Mar 20, 2024 Mar 17, 2027 R03, R01, R21
Notice of Special Interest (NOSI): Saving Lives: Integrating Overdose Education and Naloxone Distribution (OEND) into HIV Prevention and Care Settings for People Who Use Addictive Substances NOT-DA-25-031 NIDA Mar 8, 2024 May 8, 2027 R01, R34, R61/R33
Notice of Special Interest (NOSI): Epidemiologic Studies to Assess the Impact of Incretin Mimetics on New and Recurrent Cancer Risk NOT-CA-24-037 NCI Mar 7, 2024 May 9, 2026 K08, K22, R01, K99/R00, R21, P01
Notice of Special Interest (NOSI): U.S. Health in the International Perspective NOT-AG-24-004 NIA Mar 6, 2024 May 8, 2027 R01, R03
Notice of Special Interest (NOSI): Interventions to Reduce Chronic Inflammation and Inflammation-Related Morbidity in People Living with HIV/AIDS NOT-AT-24-035 NCCIH , NIA Mar 4, 2024 Nov 14, 2024 R01, R61/R33, R34, R21
Notice of Special Interest (NOSI): Mechanisms of Osteoarthritis NOT-AG-24-002 NIA , NIAMS Feb 28, 2024 May 8, 2027 R21, R01
Notice of Special Interest (NOSI): Myelin plasticity in sculping addiction neurocircuitry NOT-DA-25-028 NIDA Feb 26, 2024 Jan 8, 2027 F30, R03, F31, R01, K99/R00, R21, K01, F32
Notice of Special Interest (NOSI): Developing and Testing Multi-level Physical Activity Interventions to Improve Health and Well-Being NOT-OD-24-058 ODP , NCCIH , NCI , NIA , NIAMS , NICHD , NIMHD , NINR , OBSSR , ODS , ORWH Feb 20, 2024 Jan 8, 2027 U24, R01, R21, R34, UG3/UH3, R03
Notice of Special Interest (NOSI): Validation of Digital Health and Artificial Intelligence/Machine Learning Tools for Improved Assessment in Biomedical and Behavioral Research NOT-CA-24-031 NCI , NHLBI , NIA , NIDA , NIMH , NINR , OBSSR , ODSS Feb 15, 2024 Jul 6, 2025 R61/R33, R01, R21, R43/R44, R34, R41/R42
Notice of Special Interest (NOSI): Determining the Tri-directional Relationship Among Oral Health, Nutrition, and Comprehensive Health NOT-DE-24-011 NIDCR Feb 12, 2024 Sep 8, 2027 R21, R01
Notice of Special Interest (NOSI): Strategies to Address Stigmatizing Beliefs and Policies Affecting People Who Use Drugs NOT-DA-25-029 NIDA Jan 31, 2024 Jan 8, 2027 R01, R34
Notice of Special Interest (NOSI): Fundamental Mechanisms and Functions of Co-transmission in the Brain NOT-MH-24-105 NIMH , NIAAA , NIDA Jan 2, 2024 Feb 4, 2027 R03, R21, P50, R01, R15
Notice of Special Interest (NOSI): Neuromodulatory Control of Circuits Underlying Mental Health Relevant Behaviors NOT-MH-24-100 NIMH Jan 2, 2024 May 10, 2027 R15, R01, P50, R21, R03
Notice of Special Interest (NOSI): Advancing Genomic Technology Development for Research and Clinical Application NOT-HG-24-012 NHGRI Dec 20, 2023 Jan 10, 2027 R01, R21, R43/R44, R41/R42
Notice of Special Interest (NOSI): Addressing Health Disparities and Advancing Health Equity in NIDDK Diseases NOT-DK-24-007 NIDDK Dec 20, 2023 Jan 8, 2027 K23, R01, K08, RC2, K99/R00, K01, R03, K25, R43/R44, U01, R21, R41/R42, DP1, U34
Notice of Special Interest (NOSI): Research Council of Finland (RCF) National Institutes of Health (NIH) Partnership Program NOT-OD-24-040 OD , NCI , NEI , NIA , NIAID , NIAMS , NIBIB , NIDCR , NIDDK Dec 14, 2023 Jan 8, 2025 R01
Notice of Special Interest (NOSI): NIDCD is Interested in Supporting Research on the Impact of Post-Acute Sequelae of SARS-CoV-2 Infection on Mission Specific Sensory and Communication Disorders NOT-DC-24-001 NIDCD Dec 14, 2023 Jan 30, 2027 R41/R42, R43/R44, R01, R21
Notice of Special Interest (NOSI): Quantum Sensing Technologies in Biomedical Applications NOT-EB-23-022 NIBIB , NCATS , NCI , NEI , NHLBI , NIGMS Dec 13, 2023 Jan 27, 2027 R35, RM1, R21, R01, U01, R15, R13, K99/R00
Notice of Special Interest: Health Influences of Gender as a Social and Structural Variable NOT-OD-24-038 ORWH , FIC , NCI , NHLBI , NIA , NIAID , NICHD , NIDA , NIMH , NINDS , OAR , SGMRO Dec 8, 2023 Oct 1, 2025 K08, R01, K23, R21, K01, R03, F31, R34
Notice of Special Interest (NOSI): Development and Application of Novel Chemical Approaches to Discover Therapeutic Targets for Substance Use Disorders NOT-DA-25-027 NIDA Nov 28, 2023 May 8, 2027 K01, R21, F31, F30, R03, F32, R01, K99/R00
Notice of Special Interest (NOSI): Data Informed, Place-Based Community-Engaged Research to Advance Health Equity NOT-HL-23-110 NHLBI , NCI , NIDCR , NIEHS , NIMH , NIMHD , NINR , OBSSR , ODP , ORWH Nov 28, 2023 Jan 8, 2027 R01, R34, R21, UG3/UH3, K01, R03, P01, P50, K08, K23
Notice of Special Interest (NOSI): Tackling Acquisition of Language in Kids (TALK) R01 Research Projects NOT-DC-24-010 NIDCD , NICHD Nov 24, 2023 Nov 6, 2026 R01
Notice of Special Interest (NOSI): Telehealth for People and Families Living with Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) NOT-AG-23-060 NIA Nov 14, 2023 Nov 13, 2024 R01, R21, R61/R33
Notice of Special Interest (NOSI): Interventions to promote mental well-being in populations that experience health disparities through social, cultural, and environmental connectedness NOT-OD-23-194 ODP , NCCIH , NIA , NIBIB , NIDCR , NIMH , NIMHD , OAR , ORWH , SGMRO Nov 6, 2023 Sep 8, 2026 R21, R01, R34, UG3/UH3
Notice of Special Interest (NOSI): Pulmonary Complications of Hematopoietic Stem Cell Transplantation (HCT) NOT-HL-23-116 NHLBI Nov 1, 2023 Jan 8, 2027 R01
Notice of Special Interest (NOSI): Using Targeted Degradation of Protein and non-Protein Targets for the Development of Novel Anti-Infectives NOT-AI-23-076 NIAID Oct 31, 2023 Jul 17, 2026 R03, R01, R21, R41/R42, R43/R44
Notice of Special Interest (NOSI): Chronic Inflammation of the Oral Cavity - An Agent for Oral Mucosal Disease NOT-DE-23-007 NIDCR Oct 30, 2023 May 10, 2027 R03, R01, R21
Notice of special interest (NOSI): Adopting Techniques and Tools Developed from the BRAIN Initiative Toward NIMH Strategic Research Priorities NOT-MH-24-290 NIMH Oct 25, 2023 May 10, 2027 P50, R01, R21, R03, R15
Notice of Special Interest (NOSI): Applications of Data Science in Translational Dental, Oral, and Craniofacial Research NOT-DE-24-003 NIDCR Oct 23, 2023 May 8, 2026 UE5, R41/R42, U01, K02, K25, F30, R13, D43, F99/K00, F33, F31, K99/R00, R16, D71, R15, R43/R44, K18, K43, K08, R01, R21, K23, K01, F32, R03, G11, K22
Notice of Special Interest (NOSI): Palliative Care in the Care Continuum among Persons with Serious Heart, Lung, Blood and Sleep (HLBS) Diseases and their Caregivers NOT-HL-23-117 NHLBI , NIMHD Oct 19, 2023 Jan 8, 2027 R01
Notice of Special Interest (NOSI): Research Projects to Develop Oncoaging Models for Cancer Research NOT-CA-23-092 NCI , NIA Oct 16, 2023 Jul 31, 2027 R21, R01
Notice of Special Interest (NOSI): The Road to Prevention of Stillbirth NOT-HD-23-021 NICHD Oct 3, 2023 Nov 17, 2026 F31, R03, R15, K08, R01, R21, F30, U24, R43/R44, K23, R41/R42, R25, S06, F32, U01
Notice of Special Interest (NOSI): Advancing Rheumatic Heart Disease Research (R01) NOT-HL-23-106 NHLBI , NIAID Sep 13, 2023 Jan 8, 2027 R01
Notice of Special Interest (NOSI): Mechanisms Driving Obesity and Prostate Cancer Risk NOT-CA-23-089 NCI Aug 30, 2023 Sep 8, 2024 R01, K99/R00, R21, K08, K22
Notice of Special Interest in Research on Family Support and Rejection in the Health and Well-Being of SGM Populations NOT-OD-23-166 OD , NCI , NIA , NIAMS , NICHD , NIDDK , NIMH , NIMHD , OBSSR , ODP , ORWH , THRO Aug 28, 2023 May 8, 2026 R21, R15, R01, R34, K25, K99/R00, K01, R03, P01, K08, K23
Notice of Special Interest (NOSI): Epidemiology and Prevention in Alcohol Research NOT-AA-23-018 NIAAA , NCI Aug 24, 2023 Sep 6, 2026 R03, R21, R01, UG3/UH3, R61/R33
Notice of Special Interest (NOSI): Investigation of Biomolecular Condensates in Aging and Alzheimer's Disease (AD) and AD-related Dementias (ADRD) NOT-AG-23-037 NIA Aug 14, 2023 Nov 13, 2024 R21, R01
Notice of Special Interest (NOSI): Maternal Health and the Dental, Oral, and Craniofacial Development of their Children NOT-DE-23-005 NIDCR Aug 3, 2023 Mar 17, 2026 R21, R01
Notice of Special Interest (NOSI): Role of social function on SUD treatment and outcomes NOT-DA-25-026 NIDA Aug 1, 2023 Sep 8, 2026 R01, R21
Notice of Special Interest (NOSI): Accelerating Research in Understudied Skin Types NOT-AR-24-009 NIAMS Jul 31, 2023 Jul 17, 2026 R21, R01, R34
Notice of Special Interest (NOSI): Research on Early Allergy Determinants using Biosamples from the SUNBEAM Birth Cohort NOT-AI-23-058 NIAID Jul 27, 2023 Jul 6, 2026 R01
Notice of Special Interest (NOSI): Lymphatic System in Health and Disease (R01) NOT-HL-23-099 NHLBI , NCCIH , NIAMS , NIDCR Jul 24, 2023 Sep 8, 2026 R01
Notice of Special Interest (NOSI): Understanding Immune Evasion in Tickborne Diseases NOT-AI-23-053 NIAID Jul 24, 2023 Jul 17, 2026 R21, R01, R03
Notice of Special Interest (NOSI): Advancing Research to Address the Heterogeneity of Obesity Risk, Related Health Outcomes, and Response to Treatment NOT-HL-23-090 NHLBI Jul 7, 2023 Sep 8, 2027 R01
Notice of Special Interest (NOSI): Advancing Biomedical Research in Pulmonary Non-Tuberculous Mycobacterial (NTM) Infections NOT-AI-23-050 NIAID Jun 27, 2023 Jul 17, 2026 R21, R41/R42, R43/R44, R01, U44
Notice of Special Interest: Secondary Analyses of Existing Alcohol Research Data NOT-AA-23-011 NIAAA Jun 26, 2023 Sep 6, 2026 R21, R03, R01
Notice of Special Interest (NOSI): Using Targeted Degradation of Protein and non-Protein Targets for the Development of Novel Anti-Infectives NOT-AI-23-049 NIAID Jun 23, 2023 Jul 17, 2026 R03, R01, R41/R42, R43/R44, R21
Notice of Special Interest (NOSI): HIV Cure-Related Research in Diverse Populations NOT-AI-23-046 NIAID , NIDDK , NIMH Jun 23, 2023 May 8, 2026 R01, R21
Notice of Special Interest (NOSI): Promoting Research and Development of Vaccines Against Enteric Viruses NOT-AI-23-048 NIAID Jun 15, 2023 Jul 17, 2026 R01, R43/R44, U44, R41/R42, R21
Notice of Special Interest (NOSI): Neuropathogenesis of CNS Complications Associated with HIV NOT-MH-23-280 NIMH , NINDS Jun 15, 2023 Sep 8, 2026 K24, K08, R01, K01, K23, R15, K99/R00, F30, F32, K43, F31, T32, R03, R21, R25
Notice of Special Interest (NOSI): Eradication of HIV-1 from Central Nervous System Reservoirs NOT-MH-23-260 NIMH , NINDS Jun 15, 2023 Sep 8, 2026 R21, K43, K01, R25, K08, K99/R00, R01, F30, F32, T32, R03, R15, F31, K23, K24
Notice of Special Interest (NOSI): Clinical Studies of CNS Complications in People with HIV NOT-MH-23-255 NIMH , NINDS Jun 15, 2023 Sep 8, 2026 K43, K01, R25, K99/R00, R21, K08, F30, T32, R01, F32, F31, R03, R15, K23, K24
Notice of Special Interest (NOSI): Understanding Mucosal Immunity Against Enteric Eukaryotic Pathogens to Advance Discovery of New Interventions NOT-AI-23-045 NIAID Jun 15, 2023 Jul 17, 2026 R21, R01
Notice of Special Interest (NOSI): Impacts of Psychedelic and Dissociative Drug Policy Changes on Public Health Outcomes NOT-DA-24-010 NIDA Jun 13, 2023 Sep 8, 2026 R03, 333, R01, R15, R21
Notice of Special Interest (NOSI): Applications of Data Science in Translational Dental, Oral, and Craniofacial Research NOT-DE-23-002 NIDCR Jun 12, 2023 May 8, 2026 K43, K18, R01, K08, K99/R00, K01, K23, R21, F99/K00, F32, F31, R16, G11, K22, R15, R03, UE5, U01, R13, K25, K02, F30, F33, D43, D71
Notice of Special Interest (NOSI): Research on barriers to care and risk of HIV-associated comorbidities among vulnerable population groups NOT-HL-23-089 NHLBI Jun 8, 2023 May 8, 2025 R01
Notice of Special Interest (NOSI): Research on HIV-associated Malignancies NOT-CA-23-070 NCI Jun 8, 2023 Sep 8, 2026 R21, R01
Notice of Special Interest (NOSI): Assessing Real-World Effectiveness and Implementation of Telehealth-Guided Provider-to-Provider Communication among Rural Communities NOT-HL-23-083 NHLBI , NCI , ODP May 25, 2023 Oct 10, 2026 R01, R21
Notice of Special Interest (NOSI): Analyses of CALERIE Datasets and Biospecimens to Elucidate the Biological Effects and the Behavioral and Psychological Aspects of Sustained Caloric Restriction in Humans NOT-AG-23-024 NIA May 12, 2023 May 8, 2024 R01, R21
Notice of Special Interest (NOSI): Maximizing the Scientific Value of Secondary Analyses of Existing Cohorts and Datasets in Order to Address Research Gaps and Foster Additional Opportunities in Aging Research NOT-AG-23-020 NIA May 9, 2023 May 8, 2024 R01, R21
Notice of Special Interest (NOSI): Pre-Clinical Research on Gene Therapies for Rare Genetic Neurodevelopmental Disorders NOT-MH-23-236 NIMH Apr 28, 2023 Sep 8, 2026 R01
Notice of Special Interest (NOSI): NIMH Planning Grants for Natural History Studies of Rare Genetic Neurodevelopmental Disorders NOT-MH-23-235 NIMH Apr 28, 2023 Sep 8, 2026 R01
Notice of Special Interest (NOSI): Synthetic Biology for Biomedical Applications. NOT-EB-23-002 NIBIB , NCCIH , NCI , NHLBI , NIA , NIAID , NICHD , NIGMS Apr 14, 2023 May 17, 2026 R01, R21, R35, R41/R42, R43/R44
Notice of Special Interest (NOSI): Assembling the Addiction Organelle Interactome NOT-DA-24-007 NIDA Apr 11, 2023 Sep 8, 2026 R21, K01, R36, R03, R01
Notice of Special Interest (NOSI): Leveraging glial cells to treat addiction NOT-DA-24-006 NIDA Apr 3, 2023 Sep 8, 2026 R21, K01, R36, R01, R03
Notice of Special Interest (NOSI): Promoting Language and Communication in Minimally Verbal/Non-Speaking Individuals with Autism NOT-DC-23-009 NIDCD Apr 3, 2023 Jun 6, 2026 R13, R15, R01, U01, R21, R43/R44, R41/R42, R03
Notice of Special Interest (NOSI): Research to Address Vaccine Uptake and Implementation among Populations Experiencing Health Disparities NOT-MD-23-008 NIMHD , NCI , NIAMS , NIDCR , OBSSR , ODP , ORWH , SGMRO Mar 31, 2023 Jun 6, 2026 R01, R21
Notice of Special Interest (NOSI): Encouraging Womens Health Research within the NIDCD Mission Areas NOT-DC-23-006 NIDCD Mar 28, 2023 May 6, 2026 R15, R21, R01
Notice of Special Interest (NOSI): NIDCR Support for Research on the Physiological Involvement of Oral Cavity in Coronavirus Disease 2019 (COVID-19) NOT-DE-23-004 NIDCR Mar 8, 2023 May 8, 2026 R21, R01, UG3/UH3
Notice of Special Interest (NOSI): Research Project Grants in Valvular Heart Disease (CAROL Act) NOT-HL-23-079 NHLBI Mar 7, 2023 May 8, 2026 R01
Notice of Special Interest (NOSI): Integrative Omics Analysis of NHLBI TOPMed Data (Parent R01 Clinical Trial Not Allowed) NOT-HL-23-067 NHLBI Mar 6, 2023 May 8, 2026 R01
Notice of Special Interest: Advancing mHealth Interventions for Understanding and Preventing Alcohol-Related Domestic Violence NOT-AA-23-003 NIAAA Mar 6, 2023 Sep 8, 2026 R01, R21, R34, K99/R00
Notice of Special Interest (NOSI): Advancing Research Needed to Develop a Coccidioidomycosis (Valley fever) Vaccine NOT-AI-23-031 NIAID Feb 23, 2023 Jan 15, 2026 R01, R41/R42, R43/R44, R21, U44
Notice of Special Interest (NOSI): Enhancing Research on Deciphering Mechanisms of COVID-19-Associated Coagulopathy NOT-HL-23-080 NHLBI Feb 22, 2023 Jul 6, 2025 R01
Notice of Special Interest (NOSI): Mortality of Adolescents, Young Adults, and Other NICHD Priority Populations in the United States NOT-HD-23-001 NICHD , ODP , ORWH , SGMRO Feb 15, 2023 Sep 8, 2024 R01, R15, R21, K01, R03
Notice of Special Interest (NOSI): Research to Improve Pre-Pregnancy Care and Enhance Healthy Birth Intervals NOT-HD-23-003 NICHD Feb 9, 2023 Sep 8, 2024 R21, R03, R01
Notice of Special Interest (NOSI): Addressing the Etiology of Health Disparities and Health Advantages Among Immigrant Populations NOT-MD-23-002 NIMHD , NCI , NHLBI , NIAAA , NIDA Feb 6, 2023 Jun 6, 2026 R01, R61/R33
Notice of Special Interest (NOSI): Development of Functional Assay Sites to Evaluate Candidate -Omics Variants Associated with Heart, Lung, Blood, or Sleep Disease (R01, R41, R42, R43, R44) NOT-HL-23-066 NHLBI Jan 31, 2023 Sep 8, 2026 R41/R42, R43/R44, R01
Notice of Special Interest (NOSI): Pharmacogenomic Approaches to Enhancing HIV and Substance Use Disorder (SUD) Treatment Strategies, A jump into Precision Medicine. NOT-DA-24-001 NIDA Jan 26, 2023 May 8, 2026 R01, R03
Notice of Special Interest (NOSI): Understanding Sudden Death in the Young Through Research NOT-HL-22-040 NHLBI , NINDS Jan 19, 2023 Jan 7, 2028 R01
Notice of Special Interest (NOSI): Computational and Statistical Methods to Enhance Discovery from Health Data NOT-LM-23-001 NLM Jan 19, 2023 Jan 8, 2026 R01
Notice of Special Interest (NOSI): Research on the Etiology, Early Detection, Screening and Prevention of Early-Onset Colorectal Cancer NOT-CA-23-018 NCI Jan 19, 2023 Sep 8, 2024 K01, R01, K22, K08, R21, U34, K99/R00, P01, R34
Notice of Special Interest (NOSI): Priority Research Opportunities in Crisis Response Services NOT-MH-23-140 NIMH , NIDA , ORWH Jan 18, 2023 May 8, 2025 R21, R01, R34
Notice of Special Interest (NOSI): Adaptive Biomaterials for Cancer Biology NOT-CA-23-030 NCI Jan 10, 2023 May 7, 2025 R01, K22, K99/R00
Notice of Special Interest (NOSI): Targeting the Endocannabinoid System for Brain Health and Acute and Chronic Diseases NOT-DA-22-048 NIDA , NCI , NIDCR Jan 9, 2023 Jan 8, 2026 R01, R21, DP2, DP1, K99/R00, K01, R36, K08, R15, K24
Notice of Special Interest (NOSI): Fundamental Science Research on the Neural Circuits Underlying Sensory Processing NOT-DC-23-001 NIDCD Jan 5, 2023 Jan 8, 2026 R21, R01, R15
Notice of Special Interest (NOSI): Firearm Injury and Mortality Prevention Research NOT-OD-23-039 OBSSR , NCCIH , NIA , NIAAA , NICHD , NIDA , NIMH , NIMHD , NINR , ODP , ORWH , SGMRO Dec 16, 2022 Feb 5, 2026 R01, R34, R21, U24, R61/R33, UG3/UH3
Notice of Special Interest (NOSI): Optimization of Data Storage and Utilization for the Sequence Read Archive (SRA) NOT-GM-23-015 NIGMS , NLM , ODSS Dec 14, 2022 Dec 19, 2025 R41/R42, R43/R44, R01, K08, RM1, R21, K25, K99/R00, K23, F30, F32, F33, F31, R16, R35, R15
Notice of Special Interest (NOSI): Research to Address Ending the HIV Epidemic Initiative Goals Relevant to Substance Using Populations At-Risk for or Living with HIV NOT-DA-23-013 NIDA Dec 8, 2022 Jan 8, 2027 R34, R01
Notice of Special Interest (NOSI): The Neural Mechanisms of Multi-Dimensional Emotional and Social Representation NOT-MH-23-120 NIMH Dec 7, 2022 Jan 8, 2025 R21, R01, R03, R15
Notice of Special Interest (NOSI): Advancing Research Needed to Develop a Coccidioidomycosis (Valley fever) Vaccine NOT-AI-23-007 NIAID Nov 25, 2022 Jan 8, 2026 R21, R41/R42, R43/R44, R01
Notice of Special Interest (NOSI): Advancing Research for Tickborne Diseases (TBDs) NOT-AI-23-013 NIAID , NIAMS , NIMH , NINDS Nov 25, 2022 Jan 8, 2026 R43/R44, R15, R01, R21, R03, R41/R42
Notice of Special Interest (NOSI): Complement in Fundamental Immunology NOT-AI-23-012 NIAID Nov 23, 2022 Jan 8, 2026 R21, R01
Notice of Special Interest (NOSI): Advancing Development of Rapid Point-of-Care Hepatitis C Virus Diagnostics NOT-AI-23-001 NIAID , NCI , NIBIB Nov 23, 2022 Jan 8, 2026 R01, R41/R42, R43/R44, R21
Notice of Special Interest: Promoting Research Opportunities on HIV/AIDS in NIAMS NOT-AR-23-004 NIAMS Nov 21, 2022 Jan 8, 2028 R01, R21, 333
Notice of Special Interest (NOSI): Chemsex and HIV: prevalence, medical/psychosocial consequences, and treatment NOT-DA-24-002 NIDA Nov 14, 2022 Jan 8, 2026 R21, R01, R03
Notice of Special Interest (NOSI): Advancing Research in Lipoprotein(a) and Cardiovascular Disease (R01 Clinical Trials Allowed) and (R01 No Clinical Trials Allowed) NOT-HL-22-052 NHLBI Nov 10, 2022 Jan 8, 2026 R01
Notice of Special Interest (NOSI): Explainable Artificial Intelligence for Decoding and Modulating Neural Circuit Activity Linked to Behavior NOT-MH-23-110 NIMH , ORWH Nov 8, 2022 Feb 6, 2027 R01
Notice of Special Interest (NOSI): Chemoproteomic Approaches for Discovery of Targets and Therapeutics to Treat Substance Use Disorders NOT-DA-24-005 NIDA Nov 7, 2022 Jan 8, 2026 R03, F32, R21, F31, R01, K99/R00, F30, K01
Notice of Special Interest (NOSI) Targeting Epigenetic Regulators for Treating Addiction and Substance Use Disorders NOT-DA-24-004 NIDA Nov 3, 2022 Jan 8, 2026 R03, R01, K99/R00, R21, F31, F30, F32, K01
Notice of Special Interest (NOSI): Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R01, R21, R03) NOT-DA-23-012 NIDA Nov 2, 2022 Feb 8, 2026 R01, R03, R21
Notice of Special Interest (NOSI): Research on the Impact of Policy Changes and Emerging and Evolving Public Health Crises on NIDA Populations of Interest NOT-DA-22-084 NIDA Oct 20, 2022 Jan 8, 2026 R15, R21, R01, R03
Notice of Special Interest (NOSI): Utilization of Cohorts and Prospective Study Designs for Liquid Biopsy Assay Validation for Early Detection of Cancers NOT-CA-23-004 NCI Oct 17, 2022 Jul 2, 2025 R43/R44, R21, R01, UH2/UH3, R41/R42, U01
Notice of Special Interest (NOSI): Opportunities for HIV Cure Interventions at the Time of ART Initiation NOT-AI-22-072 NIAID , NICHD , NIMH Oct 6, 2022 Sep 8, 2025 R01, R21
Notice of Special Interest (NOSI): Understanding Exposure and Health Effects of Micro and/or Nanoplastics NOT-ES-23-002 NIEHS Oct 3, 2022 Nov 17, 2027 R21, R01
Notice of Special Interest (NOSI): Targeting the Pathogen within the Arthropod Vector NOT-AI-22-074 NIAID Oct 3, 2022 Jan 8, 2026 R01, R21
"Notice of Special Interest (NOSI): High Priority Areas in Placental Research for Healthy Pregnancies" (Reissue) NOT-HD-22-049 NICHD Sep 27, 2022 Mar 16, 2025 R01, R03, R21
Notice of Special Interest (NOSI): Halting Tuberculosis (TB) Transmission NOT-AI-22-064 NIAID Sep 20, 2022 Jan 8, 2026 R01, R21
Notice of Special Interest (NOSI): Research on the Impact of Policy Changes and Emerging and Evolving Public Health Crises on NICHD Populations of Interest NOT-HD-22-038 NICHD , NIDA Sep 14, 2022 Jan 8, 2025 R15, R03, R01, R21
Notice of Special Interest (NOSI): Basic and Translational Research on Circadian Regulation of Heart, Lung, Blood, and Sleep Disorders (R01) NOT-HL-22-043 NHLBI Sep 13, 2022 Jan 8, 2028 R01
Notice of Special Interest (NOSI): Development and Preliminary Testing of Health-related Behavioral Interventions NOT-OD-22-203 OBSSR , NCCIH , NCI , NIA , NIDA , NIDCR , NINR Sep 9, 2022 Sep 27, 2024 R01, R34, R21, UG3/UH3, R61/R33, U54, U01, R21/R33
Notice of Special Interest (NOSI): Opportunities for HIV Cure Interventions at the Time of ART Initiation NOT-AI-22-056 NIAID , NIMH Aug 5, 2022 Sep 8, 2025 R01, R21
Notice of Special Interest (NOSI): Promoting Mechanistic Research on Therapeutic and Other Biological Properties of Minor Cannabinoids and Terpenes NOT-AT-22-027 NCCIH , NCI , NEI , NIA , NIAAA , NIDA , NIDCR , NINDS , ODS , ORWH Jul 27, 2022 Jul 1, 2025 R21, R01, UG3/UH3
Notice of Special Interest (NOSI): Respiratory Complications of the Muscular Dystrophies (R01) NOT-HL-22-025 NHLBI , NICHD , NINDS Jul 18, 2022 Jan 8, 2025 R01
Notice of Special Interest (NOSI): Single-Cell Level Spatiotemporal Mapping of Dental and Craniofacial Embryogenesis NOT-DE-22-003 NIDCR Jul 18, 2022 Sep 8, 2025 R15, R01, K18, K99/R00, K02, R21, K01, R03, R16, K22
Notice of Special Interest (NOSI): Addressing Evidence Gaps in Screening NOT-OD-22-179 ODP , NIA , NIAAA , NIAMS , NICHD , NIDA , NIDCD , NIDCR , NIMH , NIMHD , NINDS , NINR , ODS , ORWH , SGMRO Jul 14, 2022 May 8, 2025 R21, R01, R61/R33, UG3/UH3, R34, U01
Notice of Special Interest (NOSI): Increasing Uptake of Evidence-Based Screening in Diverse Populations Across the Lifespan NOT-OD-22-178 ODP , NCI , NIA , NIAAA , NIAMS , NICHD , NIDA , NIDCD , NIDCR , NIMH , NIMHD , NINDS , NINR , ODS , ORWH , SGMRO Jul 14, 2022 May 8, 2025 R21, R01, UG3/UH3, R61/R33, R34, R03
Notice of Special Interest (NOSI): Research on the Health of Sexual and Gender Minority (SGM) Populations NOT-MD-22-012 NIMHD , NCCIH , NCI , NHGRI , NIA , NIAID , NIAMS , NICHD , NIDA , NIDCD , NIDCR , NIDDK , NIEHS , NINDS , NINR , ODP , ORWH , SGMRO Jul 11, 2022 Aug 8, 2025 R01, K08, K99/R00, K01, K23, R21, K25, K18, R03, P50, F99/K00, UG3/UH3, R34, R25, U01
Notice of Special Interest (NOSI): Research on Addressing Violence to Improve Health Outcomes NOT-OD-22-167 OBSSR , NIA , NIAAA , NICHD , NIDA , NIDCD , NIDCR , NIMH , NIMHD , NINR , ODP , ORWH , SGMRO Jul 8, 2022 Oct 5, 2025 R21, R01, R34, UG3/UH3
Notice of Special Interest (NOSI): Studies of Cellular/Molecular Pathobiological Mechanisms of Lung Diseases Using Human 3-Dimensional Cellular Systems (R01) NOT-HL-22-030 NHLBI Jul 5, 2022 Sep 8, 2025 R01
Notice of Special Interest (NOSI): Stimulating Research to Understand and Address Hunger, Food and Nutrition Insecurity NOT-OD-22-135 ONR , FIC , NCI , NHLBI , NIAMS , NICHD , NIDCR , NIDDK , NIMH , NIMHD , NINR , OAR , OBSSR , ODP , ODS , PN , ORWH Jun 21, 2022 Nov 29, 2024 R01, 333, R21, K01, R34, R33, R61/R33, UG3/UH3, K43
Notices of Special Interest (NOSI): High Priority Areas in Integrative Neuroscience Branch in the Division of Neuroscience and Behavior NOT-DA-22-058 NIDA Jun 2, 2022 Jan 8, 2026 R21, R03, R36, K01, K99/R00, R01
Notice of Special Interest (NOSI): Climate Change and Health NOT-ES-22-006 NIEHS , FIC , NCI , NHGRI , NHLBI , NIA , NIAID , NIAMS , NICHD , NIDCR , NIMH , NIMHD , NINDS , NINR , NLM , ODP Jun 1, 2022 May 8, 2025 R21, F31, D43, K01, R03, K43, K99/R00, U01, U19, R01, F32, K23, F30, R21/R33
Notice of Special Interest (NOSI): Diagnostics and Disease Management Tools for Use in Underserved Populations NOT-HL-22-024 NHLBI May 27, 2022 Jul 6, 2025 R01
Notice of Special Interest (NOSI): NIH Research Project Grants on Down Syndrome (R01) for the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project NOT-OD-22-123 OD , NCI , NEI , NHLBI , NIA , NIAMS , NICHD , NIDCD , NIDCR , NIMHD , NINDS May 26, 2022 May 1, 2025 R01
Notice of Special Interest: Disease Mechanisms of Prenatal and Pediatric Hydrocephalus NOT-NS-23-004 NINDS May 20, 2022 Dec 10, 2025 R01
Notice of Special Interest: Tools to Enhance the Study of Prenatal and Pediatric Hydrocephalus NOT-NS-23-003 NINDS May 20, 2022 Dec 10, 2025 R21, R01
Notice of Special Interest (NOSI): Increasing Uptake of Evidence-Based Screening in Diverse Populations Across the Lifespan NOT-OD-22-106 ODP , NCI , NIA , NIAAA , NIAMS , NICHD , NIDA , NIDCD , NIDCR , NIMH , NIMHD , NINDS , NINR , ODS , ORWH , SGMRO May 12, 2022 May 8, 2025 R03, R01, R34, R21, UG3/UH3, R61/R33, 333
Notice of Special Interest (NOSI): Addressing Evidence Gaps in Screening NOT-OD-22-107 ODP , NIA , NIAAA , NIAMS , NICHD , NIDA , NIDCD , NIDCR , NIMH , NIMHD , NINDS , NINR , ODS , ORWH , SGMRO May 12, 2022 May 8, 2025 333, R01, R34, R21, R61/R33, U01, UG3/UH3
Notice of Special Interest (NOSI): Basic Mechanisms of Cannabis and Cannabinoid Action in Cancer NOT-CA-22-085 NCI May 5, 2022 Jul 5, 2027 K22, R01, K08, K01, R21, R03, K99/R00
Understanding the Basic Mechanisms of Immune-related Adverse Events (irAEs) in Cancer Immunotherapy NOT-CA-22-063 NCI , NIAID , NIAMS , NIDCR May 3, 2022 Jul 5, 2024 R01, R21, K99/R00, K01, K08, K22, R03, R15
Notice of Special Interest (NOSI): Towards Developing a Cure for HBV in HIV/HBV Co-Infection NOT-AI-22-043 NIAID Apr 29, 2022 May 8, 2025 R01, R41/R42, R21, R43/R44
Notice of Special Interest (NOSI): Sustained Release of Antivirals for Treatment or Prevention of HIV or Treatment of Latent TB/HBV (SRATP) NOT-AI-22-042 NIAID , NIMH Apr 28, 2022 May 8, 2025 R01
Notice of Special Interest: Achieving Tissue Robustness Through Harnessing Immune System Plasticity NOT-DE-22-005 NIDCR Apr 26, 2022 Sep 9, 2025 R21, R01
Notices of Special Interest (NOSI): High Priority Areas in Genetics, Epigenetics, and Developmental Neuroscience Branch in the Division of Neuroscience and Behavior NOT-DA-23-004 NIDA Apr 14, 2022 Sep 9, 2025 R01
Notice of Special Interest (NOSI) - Emerging and Existing Issues of Coronavirus Disease 2019 (COVID-19) Research Related to the Health and Well-Being of Women, Children and Individuals with Physical and/or Intellectual Disabilities NOT-HD-22-002 NICHD , NIDA , NIEHS , NINDS , OBSSR , ORWH Mar 28, 2022 Jun 6, 2024 R01, R21
Notice of Special Interest (NOSI): Research using implementation science to support the delivery of evidence-based practices in community-based mental or general medical healthcare settings NOT-MH-22-170 NIMH , NIDA Mar 25, 2022 May 8, 2025 R21, R01, R34
Notice of Special Interest (NOSI): Technological Innovations for Advancing Clinical SPECT Imaging NOT-EB-22-006 NIBIB Mar 21, 2022 May 8, 2024 R21, F30, K01, R13, K23, K25, R43/R44, K08, R01, K99/R00, R41/R42, F32, R03, F31
Notice of Special Interest (NOSI): Leveraging Data Science to Bring Actionable Insights for Substance Use Prevention and Treatment NOT-DA-23-006 NIDA Mar 1, 2022 Sep 8, 2025 R21, R01, R03, 333
Notice of Special Interest (NOSI): Optimizing Vascularized Composite Allograft Survival NOT-AI-22-023 NIAID Feb 23, 2022 May 8, 2026 R21, R01
Notice of Special Interest (NOSI): Epidemiology of Drug Abuse NOT-DA-22-004 NIDA Feb 23, 2022 Sep 8, 2025 R21, R01, 333, R03
Notice of Special Interest (NOSI): Public Health Research on Cannabis NOT-DA-22-003 NIDA Feb 18, 2022 May 5, 2025 R21, R01, 333, R03
Notice of Special Interest (NOSI): Research on Drowning Prevention NOT-HD-21-048 NICHD , NIMHD , ODP Feb 15, 2022 May 8, 2024 R01, K23, K08, K99/R00, R21, R03
Notice of Special Interest (NOSI): Research Addressing Eye and Vision Health Equity/Health Disparities NOT-EY-22-004 NEI , NIMHD Feb 14, 2022 Jan 25, 2025 R01, UG1, F31, R21, 333, K99/R00, K08, F30, K23, R43/R44, R34, R41/R42, F32
Notice of Special Interest (NOSI): Priority Research Opportunities in Crisis Response Services NOT-MH-22-110 NIMH , NIDA , ORWH Feb 8, 2022 May 8, 2025 R21, R01, R34, R43/R44
Notice of Special Interest: NIMH Priorities on Research on Aggression and Violence Against Others NOT-MH-22-095 NIMH Feb 3, 2022 Jan 8, 2025 R36, R01, R34, R21, F32, R21/R33, R03, R61/R33, U01, K08, R15, K23, P50, F30, K99/R00, F31, K22, K01
Notice of Special Interest: Neuro-Glia Mechanisms Governing Complex Behaviors (R01 Clinical Trial Optional) NOT-MH-22-090 NIMH Feb 3, 2022 May 8, 2025 R21, R01
Notice of Special Interest (NOSI): Inclusion of Economic Factors and Outcomes in Infectious Disease Modeling Studies NOT-GM-22-021 NIGMS Feb 1, 2022 Jan 8, 2025 RM1, R35, R01, K99/R00, K25, K08, F30, K23, F33, R15, F32, F31
Notice of Special Interest (NOSI): Research on barriers to care and risk of HIV-associated comorbidities among vulnerable population groups NOT-HL-22-010 NHLBI Jan 31, 2022 May 8, 2025 R01
Notice of Special Interest (NOSI): Research to Prevent Drug Use, Misuse and Addiction NOT-DA-23-001 NIDA , ODP Jan 21, 2022 May 8, 2025 R01, R21, R34, R03
Notice of Special Interest (NOSI): COVID-19 Pandemic Mental Health Research NOT-MH-22-100 NIMH Jan 19, 2022 Jan 8, 2025 R21, R34, R01
Notice of Special Interest (NOSI): Advancing NEI AGI Research on newly Identified Factors Into Models of Visual System Regeneration NOT-EY-22-002 NEI Jan 10, 2022 Feb 10, 2025 R43/R44, R21, R15, R41/R42, R01, R24
Notice of Special Interest (NOSI): Disparities Affecting Healthcare Utilization and Health Outcomes Among Childhood Cancer Survivors NOT-CA-22-029 NCI Jan 7, 2022 Oct 9, 2024 R01, R21, P01, R03
Notice of Special Interest: Development and Implementation of Clinical Informatics Tools to Enhance Patients Use of Genomic Information NOT-HG-22-011 NHGRI Jan 6, 2022 Dec 31, 2025 R01, R21, U24, R43/R44, R41/R42
Notice of Special Interest (NOSI): Advancing Innovative Non-invasive Physiologic Monitoring To Improve Fetal Assessment NOT-HD-21-053 NICHD Dec 28, 2021 May 8, 2024 R03, R01, R41/R42, R43/R44, R21
Notice of Special Interest: Research on Pain, Pain Management, and Opioids in Aging NOT-AG-22-004 NIA Dec 22, 2021 Jan 8, 2025 F31, P01, K99/R00, K08, R01, K01, R43/R44, F32, 332, F33, F99/K00, R15, K24, R21, K02, K25, R25, F30, K23, R36, R41/R42, SB1, K76, K22, K07, R13, R21/R33, U19
RESCINDED - Notice of Special Interest (NOSI): Diagnostics and Disease Management Tools for Use in Underserved Populations NOT-HL-22-006 NHLBI Dec 22, 2021 Jul 6, 2026 R01
Notice of Special Interest (NOSI): Promoting Fundamental Research on Mitochondrial Involvement in Lung Diseases and Sleep Disorders NOT-HL-22-003 NHLBI Dec 22, 2021 Apr 5, 2025 R01
Notice of Special Interest (NOSI) Pediatric COVID-19 and Respiratory Viral Co-infection NOT-HL-22-004 NHLBI , NICHD , NIAID Dec 21, 2021 Sep 8, 2025 R01, R21
Notice of Special Interest (NOSI): Epidemiologic studies in Asian Americans, Native Hawaiians, and Pacific Islanders (Parent R01 Clinical Trial Not Allowed) NOT-HL-23-001 NHLBI , NIA , NCI , NIEHS , NIMHD , NINDS , NHGRI Dec 20, 2021 Nov 19, 2024 R21, R01
Notice of Special Interest (NOSI): Advancing Research Needed to Develop a Universal Influenza Vaccine NOT-AI-22-013 NIAID Dec 13, 2021 Jan 8, 2025 R01, R21
Notice of Special Interest (NOSI): Methods Development for Genomic Studies of Genetic Variation, Function, and Disease NOT-HG-22-007 NHGRI Dec 9, 2021 Nov 5, 2024 R41/R42, R01, R43/R44, R21
Notice of Special Interest (NOSI): Epidemiology and Prevention of Alcohol Misuse in Understudied Young Adult Populations; Military, Workforce, and Community College NOT-AA-22-001 NIAAA Dec 9, 2021 Sep 9, 2025 R21, R03, R01, R43/R44, R41/R42
Notice of Special Interest (NOSI): Electronic Nicotine Delivery Systems (ENDS) and Alternative Nicotine and Tobacco Delivery Systems: Population, Clinical and Applied Prevention Mechanisms of Health Effects NOT-OD-22-023 ODP , NCI , NIDA , NIMHD , NIDCR Dec 8, 2021 May 9, 2024 R21, R01, 333, R34, R03, R61/R33
Notice of Special Interest (NOSI): Research on Interprofessional Teamwork and Coordination During Cancer Diagnosis and Treatment NOT-CA-22-014 NCI Dec 8, 2021 Oct 9, 2024 R03, R01, R21, P01
Notice of Special Interest (NOSI): Accelerating Malaria Vaccine Discovery NOT-AI-22-014 NIAID Dec 1, 2021 Jan 8, 2025 R01
Notice of Special Interest (NOSI): Research in the Chemistry and Pharmacology of Addictive Drugs NOT-DA-23-002 NIDA Nov 30, 2021 Jan 8, 2025 R03, R21, R01, K99/R00, R36, K01
Notice of Special Interest (NOSI): Examining Effects of HIV Pre-Exposure Prophylaxis (PrEP) on Heart, Lung, Blood, and Sleep Function NOT-HL-21-025 NHLBI Nov 24, 2021 May 5, 2024 R01
Notice of Special Interest (NOSI): Accelerating Progress in Celiac Disease Research NOT-AI-22-004 NIAID , NIAMS , NCCIH , NCI Nov 23, 2021 Jan 8, 2025 R03, R21, U01, U44, R01, R34, P01, R61/R33
Notice of Special Interest: Expanding the Otitis Media Research Workforce: Focus on Early Stage Investigators NOT-DC-22-001 NIDCD Nov 23, 2021 Sep 8, 2025 R21, R01, U01
Notice of Special Interest (NOSI): Mechanistic studies on the impact of substance use in sex and gender differences in HIV-associated neurocognitive disorders NOT-DA-22-047 NIDA , ORWH Nov 19, 2021 Jan 8, 2025 R21, R01
Notice of Special Interest (NOSI): The Functional Oral Microbiome NOT-DE-21-015 NIDCR , ORWH Nov 19, 2021 Sep 7, 2025 R01, R21
Notice of Special Interest (NOSI): Secondary Analysis of Posttraumatic Psychopathology Data NOT-MH-22-045 NIMH Nov 18, 2021 Jan 8, 2025 R01, R21, K08, F30, K01, K23, K22, F32, F31, R03, R36, K99/R00, R15, F99/K00
Notice of Special Interest (NOSI): Heart, Lung, Blood and Sleep Focused Ancillary Studies to Large Ongoing Clinical Studies (Revised) NOT-HL-21-030 NHLBI Nov 8, 2021 May 8, 2025 R01
Notice of Special Interest (NOSI): Improving Outcomes in Cancer Treatment-Related Cardiotoxicity NOT-CA-22-001 NCI , NHLBI Nov 4, 2021 Nov 6, 2024 R01, R03, R21, P01
Notice of Special Interest (NOSI): IDEA2Health: Innovative Data Evaluation and Analysis to Health NOT-HL-22-001 NHLBI Oct 26, 2021 Jan 8, 2025 R01
Notice of Special Interest (NOSI): Somatic Cell Gene Editing Therapies To Improve Transplantation Outcomes NOT-AI-21-080 NIAID , NHLBI Oct 18, 2021 Jan 8, 2025 R21, R01
Notice of Special Interest (NOSI): Promoting research to understand vascular contributions to cognitive impairment and dementia (VCID) NOT-HL-23-002 NHLBI , NINDS , NIA Oct 14, 2021 May 8, 2025 R01
Notice of Special Interest (NOSI): Biologic Factors Underlying Dental, Oral, and Craniofacial Health Disparities NOT-DE-21-013 NIDCR , NCI , NIMHD Oct 7, 2021 Jan 8, 2025 R21, R01
Notice of Special Interest (NOSI): Dietary Effects on Nutrient Sensing Pathways in Tumor Etiology and Prevention NOT-CA-21-121 NCI Oct 4, 2021 Sep 8, 2024 K22, K08, R15, R01, R21, K99/R00,
Notice of Special Interest (NOSI): Evaluation of sex differences on HIV-associated comorbidities in the context of stimulant use NOT-DA-21-020 NIDA Sep 9, 2021 Jan 8, 2025 R01
Notice of Special Interest (NOSI): Promoting Cardiovascular and Cardiometabolic Health in Early Stages of the Lifecourse: Pre-adolescence Through Adolescence to Young Adulthood NOT-HL-21-015 NHLBI Aug 30, 2021 Jun 6, 2026 R01
Notice of Special Interest (NOSI): Social, Behavioral, and Economic Impact of COVID-19 in Underserved and Vulnerable Populations NOT-MH-21-330 NIMH , NEI , ODP , SGMRO , NIDA , OBSSR , NIAAA , NINR , NIDCR , NIMHD , ORWH , NICHD , NIDCD , NIA , NCCIH Aug 20, 2021 Sep 8, 2024 R01, UG3/UH3
Notice of Special Interest (NOSI): International Research Collaboration on Drug Abuse and Addiction Research NOT-DA-21-064 NIDA Aug 12, 2021 Sep 8, 2024 R01, R03, R21, 333
Notice of Special Interest: Advancing Research in Gastrointestinal Dysfunction in People with Neurodevelopmental Disorders NOT-DK-21-024 NIDDK Aug 6, 2021 Jul 16, 2024 R01
RESCINDED - Notice of Special Interest (NOSI): Somatic Cell Gene Editing Therapies To Improve Transplantation Outcomes NOT-AI-21-067 NIAID , NHLBI Aug 6, 2021 Sep 8, 2024 R21, R01
Notice of Special Interest (NOSI): Precision Imaging of Oral Lesions NOT-DE-21-010 NIDCR , NCI Aug 6, 2021 Sep 10, 2024 R21, R01
Notice of Special Interest (NOSI): Using the Collaborative Cross (CC) Mouse Model for Immunoregulatory and Infectious Disease Research NOT-AI-21-071 NIAID Jul 29, 2021 Sep 8, 2024 R01, R21
Notice of Special Interest (NOSI): Immune Responses to Arthropod Feeding on Vertebrate Hosts NOT-AI-21-059 NIAID Jul 29, 2021 Sep 8, 2024 R01, R21
Notice of Special Interest (NOSI): Understanding the Immune Functions of DEAD/H-box Helicases NOT-AI-21-066 NIAID Jul 22, 2021 Sep 8, 2024 R21, R01
Notice of Special Interest: Advancing Research in Gastrointestinal Dysfunction in People with Neurodevelopmental Disorders NOT-NS-22-003 NINDS , NICHD Jul 14, 2021 Jul 17, 2024 R01, R21
RESCINDED - Notice of Special Interest (NOSI): International Research Collaboration on Drug Abuse and Addiction Research NOT-DA-21-002 NIDA Jul 14, 2021 Sep 8, 2024 R01, 333, R03, R21
Notice of Special Interest (NOSI): High Priority Areas in Placental Research for Healthy Pregnancies NOT-HD-21-040 NICHD Jul 7, 2021 Oct 6, 2024 R01, R21, R03
Notice of Special Interest (NOSI) HIV/AIDS in the Era of COVID-19: When Pandemics Collide NOT-AI-21-057 NIAID , NIMH , NIDA Jun 25, 2021 May 8, 2024 R01, R21
Notice of Special Interest (NOSI): Harnessing Big Data to Halt HIV NOT-AI-21-054 NIAID , NIDA , NIMH Jun 22, 2021 May 8, 2024 R01
Notice of Special Interest (NOSI): Advancing HIV/AIDS Research through Computational Neuroscience NOT-DA-21-030 NIDA Jun 22, 2021 Jan 8, 2025 R01, R21, R03, DP2, DP1, K99/R00, K01, R36, P01, R15, K24
Notice of Special Interest (NOSI): HIV Drug Resistance Assays and Actionable Data Dissemination Strategies NOT-AI-21-056 NIAID , NIDA Jun 17, 2021 May 8, 2024 R01, R21, U01, U24, R41/R42, R43/R44
Notice of Special Interest: NIDCD Health Disparities and Inequities Research NOT-DC-21-003 NIDCD , SGMRO Jun 11, 2021 May 8, 2024 R01, R21, P50, F30, F31, F32, F99/K00, K01, K08, K18, K23, K24, K25, K99/R00, 333, R41/R42, R43/R44
Notice of Special Interest: Advanced Computational Approaches to Elucidate Disease Pathology and Identify Novel Therapeutics for Addiction NOT-DA-21-004 NIDA May 17, 2021 Jan 8, 2025 R01
Notice of Special Interest: Public Policy Effects on Alcohol-, Cannabis-, Tobacco-, and Other Drug-Related Behaviors and Outcomes NOT-AA-21-028 NIAAA , NIDA , NCI May 5, 2021 Sep 8, 2024 R01, R03, R21
Notice of Special Interest (NOSI): Leveraging transformative connectome resources in model organisms to elucidate the neurobiology of substance use disorders NOT-DA-21-006 NIDA Apr 30, 2021 Sep 8, 2024 R01, R03, R21, 333
Notice of Special Interest (NOSI): Leveraging Longitudinal Studies in Animal Models to Identify Neural Mechanisms of Vulnerability and Resilience to Substance Use Disorder NOT-DA-21-003 NIDA Apr 30, 2021 Sep 8, 2024 R01, R21, R15, R03
Notice of Special Interest (NOSI): Research on the Impact of the Covid 19 Pandemic and Risks for Abuse and Injury Among Vulnerable Children and Youth NOT-HD-21-026 NICHD , SGMRO Apr 27, 2021 May 8, 2024 R01, R03, R21, K22, R25
Notice of Special Interest (NOSI): Reproductive Health, Pregnancy, and Parenting among Women with Disabilities NOT-HD-21-025 NICHD Apr 27, 2021 May 31, 2024 R01, R03
Notice of Special Interest (NOSI): Improving Patient Adherence to Treatment and Prevention Regimens to Promote Health NOT-OD-21-100 OBSSR , NIMHD , NIDA , NIMH , ORWH , NIDCD , SGMRO , ODP , NIA , NHLBI , NCI , NINR , NCCIH , NEI , NICHD Apr 8, 2021 Jun 8, 2024 R01, R21, R03, R41/R42, R43/R44, R21/R33, UG3/UH3, R34
Notice of Special Interest (NOSI): Identification of Biomarkers of HIV Pathogenesis and Substance Use Disorder Comorbidity NOT-DA-21-014 NIDA Mar 31, 2021 Sep 8, 2024 R01, R21, DP2, DP1, K99/R00, K01, R36, P01, R15, K24
Notice of Special Interest (NOSI): Deciphering the Mosaic of Glia in the Addicted Brain NOT-DA-21-001 NIDA Mar 29, 2021 Sep 10, 2024 R21, R01, R15
Notice of Special Interest (NOSI): Stimulate Research on the Diagnosis, Treatment, and Mechanistic Understanding of Postural Orthostatic Tachycardia Syndrome (POTS) NOT-HL-21-008 NHLBI , NINDS Mar 26, 2021 May 8, 2024 R01
Notice of Special Interest (NOSI): Synthetic Psychoactive Drugs and Strategic Approaches to Counteract Their Deleterious Effects NOT-DA-21-028 NIDA Mar 25, 2021 Sep 8, 2024 R01, R21, R03
Notice of Special Interest (NOSI): Basic Research on Fentanyl and Synthetic Fentanyl Analogs: Signaling, Neurobiology, and Pharmacology NOT-DA-21-033 NIDA Mar 24, 2021 Sep 8, 2024 R01, R21
Notice of Special Interest (NOSI): Fundamental Science Research on Complementary and Integrative Health Approaches, Including Natural Products or Mind and Body Interventions NOT-AT-21-006 NCCIH Mar 19, 2021 Sep 8, 2024 R01, R21
Notice of Special Interest (NOSI): Using Systems Science Methodologies to Protect and Improve Child and Reproductive Population Health NOT-HD-20-032 NICHD , ODP , NCI Mar 10, 2021 May 8, 2024 R01
Notice of Special Interest (NOSI) in Reducing Suicide Risk in Young People in Low- and Middle-Income Countries and Low-Resource Settings NOT-MH-21-090 NIMH Mar 2, 2021 May 8, 2024 R01, R33, R61/R33, R34, R21
Notice of Special Interest (NOSI): Using Data to Advance HIV Epidemic Knowledge and Program Planning NOT-DA-21-007 NIDA Feb 26, 2021 Sep 8, 2024 R01, R21
Notice of Special Interest (NOSI): Promoting Research on Interoception and Its Impact on Health and Disease NOT-AT-21-002 NCCIH , NIDA , ORWH , NIMH , NIDCR , OBSSR , NIA , NIEHS , NCI Jan 22, 2021 May 7, 2024 R01, R21
Notice of Special Interest: Alcohol-induced Tissue-specific and Organ System Diseases (R01/R21/R03) NOT-AA-20-024 NIAAA Jan 4, 2021 May 8, 2024 R01, R21, R03
Notice of Special Interest (NOSI) regarding the Use of Human Connectome Data for Secondary Analysis NOT-MH-21-175 NIMH , NEI , NIA , NIDA Dec 23, 2020 May 8, 2024 R01, R21
Notice of Special Interest (NOSI) regarding the Use of Human Connectome Data for Secondary Analysis NOT-MH-21-075 NIMH , NEI , NIDA , NIA Dec 18, 2020 May 8, 2024 R01, R21
Notice of Special Interest (NOSI): The Influence of Host Resilience on Heterogeneity of Acute Respiratory Distress Syndrome/Acute Lung Injury (ARDS/ALI) NOT-HL-20-814 NHLBI Sep 15, 2020 Jul 6, 2024 R01
Notice of Special Interest (NOSI): Stimulating Intervention Research to Reduce Cardiopulmonary Impacts of Particulate Matter in Air Pollution among High-Risk Populations NOT-HL-20-788 NHLBI , NIEHS Jul 16, 2020 Sep 8, 2025 R01
Notice of Special Interest: Promoting Fundamental and Applied Research in Inflammation Resolution NOT-ES-20-018 NIEHS , NHLBI , NIAMS May 27, 2020 May 31, 2024 R21, R01

Expired NOSIs

Title Notice Number Organization Release
Date
Expiration
Date
Activity
Code(s)
Notice of Special Interest (NOSI): Ending the HIV Epidemic (EHE) NOT-AI-23-070 NIAID NHLBI NIA NIAAA NICHD NIDA NIDDK NIMH NIMHD NINR OAR Sep 29, 2023 Jan 10, 2024 R21, R01, R34
Notice of Early Expiration and Reissuance of NOT-HL-22-010 "Notice of Special Interest (NOSI): Research on barriers to care and risk of HIV-associated comorbidities among vulnerable population groups" NOT-HL-23-096 NHLBI Jun 28, 2023 n/a R01
Notice of Special Interest (NOSI): Promoting Research on COVID-19 and Rheumatic, Musculoskeletal and Skin Diseases NOT-AR-23-008 NIAMS Dec 29, 2022 Jan 8, 2024 R01, R21
Notice of Special Interest (NOSI): Research on the Health of Bisexual and Bisexual+ People NOT-OD-22-166 OD NCCIH NIA NIAAA NIAID NICHD NIDA NIDCR NIMH NIMHD NINDS ODP Aug 11, 2022 Sep 8, 2023 K24, U01, R01, K01, R15, R03, K76, R34, K99/R00, T32, F32, UG3/UH3, R21, K23, F31
Notice of Special Interest (NOSI): Advancing Research on Early Pregnancy Loss NOT-HD-22-026 NICHD ORWH Jul 5, 2022 n/a R01, R21
Notice of Special Interest (NOSI): Research to Support Regulatory Science on Infant Formula NOT-HD-22-016 NICHD OD ODS Jun 13, 2022 May 8, 2023 R03, R41/R42, R43/R44, R01, 333, R21
Notice of Special Interest (NOSI): IMPROVE Initiative: Implementation Science to Advance Maternal Health and Maternal Health Equity NOT-OD-22-125 OD May 5, 2022 Jul 17, 2022 R01, R03, R21
Notice of Special Interest: Research on Alcohol and Coronavirus Disease (COVID-19) within the Mission of NIAAA NOT-AA-22-012 NIAAA Apr 29, 2022 Mar 6, 2024 R01, R03, R21, K99/R00
Notice of Special Interest (NOSI): Dissemination and Implementation Research to Advance Mental, Emotional, and Behavioral Health Preventive Interventions in School Settings NOT-AT-22-004 NCCIH NICHD NIMH NIMHD OBSSR ODP ORWH Mar 29, 2022 Mar 17, 2024 R01, R03, R21, R34
Notice of NIDA Participation in NOT-MH-21-105, "Notice of Special Interest: Advancing Health Communication Research on HIV Prevention, Treatment and Cure" NOT-DA-21-079 NIDA Feb 16, 2022 n/a R21, R01, R34, DP1, DP2, R03
Notice of NHLBI Participation in NOT-MD-22-006, "Notice of Special Interest (NOSI): Research to Address Vaccine Hesitancy, Uptake, and Implementation among Populations that Experience Health Disparities" NOT-HL-22-012 NHLBI Feb 14, 2022 n/a R01
Notice of Special Interest (NOSI): Addressing Accessibility Inequities with COVID Home-Based Testing for Individuals with Visual Impairment NOT-EY-22-010 NEI Feb 4, 2022 Mar 9, 2024 R41/R42, R15, 333, R01, R43/R44, R21
Notice of Special Interest (NOSI): Validation of Digital Health and Artificial Intelligence Tools for Improved Assessment in Epidemiological, Clinical, and Intervention Research NOT-CA-22-037 NCI NHLBI NIA NIDA NIMH NINR OBSSR Jan 27, 2022 Mar 9, 2024 R01, R03, R21, R43/R44, R41/R42, R33, R34, R61/R33
RESCINDED - Notice of Special Interest (NOSI): Enhancing Research on Deciphering Mechanisms of COVID-19-Associated Coagulopathy NOT-HL-23-003 NHLBI Jan 21, 2022 Jul 6, 2022 R01
Notice of NIDA's Participation in NOT-MD-22-006 "Notice of Special Interest (NOSI): Research to Address Vaccine Hesitancy, Uptake, and Implementation among Populations that Experience Health Disparities" NOT-DA-22-002 NIDA Jan 20, 2022 n/a R01, 333, R21
Notice of Special Interest (NOSI): Analyses of CALERIE Datasets and Biospecimens to Elucidate the Biological Effects and the Behavioral and Psychological Aspects of Sustained Caloric Restriction in Humans NOT-AG-21-028 NIA Jan 10, 2022 May 8, 2023 R01, R21
Notice of Special Interest: Promoting Research on COVID-19 and Rheumatic, Musculoskeletal and Skin Diseases NOT-AR-22-012 NIAMS Dec 28, 2021 Jan 8, 2023 R21, R01
Notice of Special Interest (NOSI) in Migraine and Headache Research NOT-NS-22-051 NINDS Dec 27, 2021 May 8, 2022 U01, K01, UG3/UH3, K22, K99/R00, K02, K08, R01, F30, K23, F32, R21, F31, R61/R33
Notice of Special Interest (NOSI) in NINDS mission relevant Pain Research NOT-NS-22-050 NINDS Dec 27, 2021 May 8, 2022 K01, UG3/UH3, K99/R00, K22, K08, R01, K02, F30, K23, R21, F32, F31, U01, U24, R61/R33
RESCINDED - Notice of Special Interest (NOSI): Research to Address Vaccine Hesitancy, Uptake, and Implementation among Populations that Experience Health Disparities NOT-MD-22-006 NIMHD ODP NIDA NIAID SGMRO NIMH ORWH NINR NCI NIDCR OBSSR Dec 21, 2021 Jan 8, 2023 R01
Notice of Special Interest (NOSI): Electronic Nicotine Delivery Systems (ENDS) and Alternative Nicotine and Tobacco Delivery Systems: Basic Mechanisms of Health Effects NOT-OD-22-022 ODP NIDCR NCI NIEHS NIDA Dec 9, 2021 May 9, 2023 R01, R61/R33, R21, 333, R03
Notice of Special Interest (NOSI): Molecular and Genetic Characterization of Inborn Errors of Immunity NOT-AI-21-082 NIAID Nov 29, 2021 Mar 20, 2024 R01, R21
Notice of Special Interest (NOSI): Basic and Translational Oral Health Research Related to HIV/AIDS NOT-DE-21-019 NIDCR Nov 23, 2021 May 8, 2023 R21, R01
Notice of NHLBI Participation in NOT-AT-21-002 "Notice of Special Interest (NOSI): Promoting Research on Interoception and Its Impact on Health and Disease (R01) NOT-HL-21-037 NHLBI Oct 26, 2021 n/a R01
Notice of Special Interest (NOSI): Dietary, Physical Activity, Sedentary Behavior and Sleep Assessment Methodologies Among Infants and Young Children (Birth to 5 years) through Adults NOT-CA-21-108 NCI NICHD NHLBI Oct 4, 2021 May 8, 2023 R01
NOSI: Notice of Special Interest: Resilience and Vulnerability following Acute Heart, Lung, Blood, and Sleep Insults in People with HIV (R01, Clinical Trial Not Allowed) NOT-HL-22-002 NHLBI Sep 30, 2021 Jan 8, 2024 R01
Notice of Special Interest (NOSI): Promoting Pain Research Within the NIAMS Mission Areas NOT-AR-22-007 NIAMS Sep 23, 2021 Jan 10, 2023 R01, R21, R15, R33, R13, R34, K99/R00, K24, K01, K25, K23, K08, 332
Notice of Special Interest (NOSI): Maximizing the Scientific Value of Secondary Analyses of Existing Cohorts and Datasets in Order to Address Research Gaps and Foster Additional Opportunities in Aging Research NOT-AG-21-020 NIA Aug 23, 2021 Sep 8, 2023 R01, R21
Notice of Special Interest (NOSI): Advancing the development of tumor site-activated small molecules NOT-CA-21-101 NCI Aug 16, 2021 Jan 8, 2024 R01, R15, R21
Notice of NHLBI Participation in NOT-HD-21-027 "Notice of Special Interest (NOSI): Navigating Pediatric to Adult Health Care: Lost in Transition" NOT-HL-21-021 NHLBI Jul 13, 2021 n/a R01
Notice of Special Interest (NOSI): Integration of Individual Residential Histories in Cancer Research NOT-CA-21-092 NCI Jul 9, 2021 Mar 8, 2024 R01, R21
Notice of Special Interest (NOSI): Integrative Omics Analysis of NHLBI TOPMed Data (Parent R01 Clinical Trial Not Allowed) NOT-HL-21-017 NHLBI Jul 6, 2021 May 8, 2023 R01
Notice of Special Interest (NOSI): Electronic Nicotine Delivery Systems (ENDS) and Alternative Nicotine and Tobacco Delivery Systems: Population, Clinical and Applied Prevention Mechanisms of Health Effects NOT-OD-21-137 ODP NIMHD NCI NIDA NIDCR Jun 28, 2021 Dec 8, 2021 333, R34, R01, R21, R03
Notice of Special Interest (NOSI): Electronic Nicotine Delivery Systems (ENDS) and Alternative Nicotine and Tobacco Delivery Systems: Basic Mechanisms of Health Effects NOT-OD-21-127 ODP NIEHS NIDCR NIDA NCI Jun 28, 2021 May 8, 2023 333, R03, R01, R21
Notice of Special Interest (NOSI): New Information Technology-Enabled Care Delivery Models to Improve Depression Care in Cancer NOT-CA-21-085 NCI Jun 22, 2021 Mar 8, 2024 R01, R21
Notice of Special Interest (NOSI): Navigating Pediatric to Adult Health Care: Lost in Transition NOT-HD-21-027 NICHD NIAAA NCI NIMH NIAMS OBSSR NIBIB NIDCR Jun 22, 2021 Jan 8, 2024 R01, R21, R43/R44, R41/R42
Notice of Special Interest (NOSI): Reduction of Sudden Unexpected Infant Death and Sudden Infant Death Syndrome NOT-HD-21-032 NICHD May 26, 2021 May 8, 2023 R01, R03, R21
Notice of Special Interest (NOSI): Biology of Lung and Head and Neck Preneoplasia NOT-CA-21-057 NCI May 6, 2021 May 8, 2023 R21, R01
Notice of Special Interest (NOSI): Early-life Factors and Cancer Development Later in Life NOT-CA-21-074 NCI May 5, 2021 Mar 8, 2024 R01, R21, R03
RESCINDED - Notice of Special Interest (NOSI): NIH Research Project Grant (R01) Applications from Individuals from Diverse Backgrounds, Including Under-Represented Minorities NOT-NS-21-049 NINDS NIAAA NIDA May 3, 2021 May 8, 2023 R01
Notice of Special Interest (NOSI): Research on Strategies to Enhance Mental Health Interventions and Services within Employment and Job Training Settings NOT-MH-21-230 NIMH NIDA Apr 16, 2021 Sep 8, 2023 R01, R34, R43/R44, R21
Notice of Special Interest (NOSI): Developing and Testing Multilevel Physical Activity Interventions to Improve Health and Well-Being NOT-OD-21-087 ODP NCCIH NCI NIA NIAAA NIAMS NICHD NIDCD NIMH NIMHD NINR OBSSR ORWH Apr 6, 2021 Feb 16, 2024 R01, R21, 333, R03
Notice of Special Interest: Research to Advance the Understanding and Management of the Multiple Organ Dysfunction Syndrome in Children (R01, R21) NOT-HD-21-024 NICHD Apr 1, 2021 May 8, 2023 R01, R21
Notice of Special Interest (NOSI): COVID-19 Related School Disruptions Impact on Mental Health, Cognitive, Social, and Emotional Development of Children NOT-MH-21-225 NIMH NICHD Mar 31, 2021 Sep 8, 2022 R01
Notice of Special Interest (NOSI): Investigations on Inborn Errors of Immunity/Primary Immunodeficiencies NOT-AI-21-032 NIAID Mar 23, 2021 Mar 20, 2024 R01, R21, R03
RESCINDED - Notice of Special Interest (NOSI): Integrative Omics Analysis of NHLBI TOPMed Data (Parent R01 Clinical Trial Not Allowed) NOT-HL-21-007 NHLBI Mar 16, 2021 May 8, 2023 R01
Notice of Special Interest (NOSI): Multi-Level HIV Prevention Interventions for Individuals at the Highest Risk of HIV Infection NOT-MD-21-014 NIMHD NIMH NIDA Mar 3, 2021 May 8, 2021 R01
Notice of Special Interest (NOSI): Neurological and Neurocognitive Sequelae from SARS-CoV-2 Infection and COVID-19 in Aging and Age-Related Neurodegeneration NOT-AG-21-016 NIA Feb 26, 2021 May 8, 2023 R01, R21, R03
Notice of Special Interest (NOSI): Hearing Healthcare for Adults: Improving Access and Affordability NOT-DC-21-001 NIDCD Feb 16, 2021 Jan 8, 2024 R01, R21, U01, R43/R44, R41/R42
Notice of Special Interest (NOSI): Complement in Basic Immunology (CIBI) NOT-AI-21-008 NIAID Feb 4, 2021 Jan 8, 2023 R01, R21
Notice of Special Interest (NOSI): Understanding the effects of cancer and cancer treatment on aging trajectories and aging outcomes NOT-CA-21-031 NCI NIA Jan 27, 2021 Jan 8, 2024 R21, R03, R01, U01, P01, K99/R00, K08, R43/R44, R41/R42, R13, R21/R33, K01, K23
Notice of Special Interest (NOSI): NIDCR Support for Research on the Physiological Involvement of Oral Cavity in Coronavirus Disease 2019 (COVID-19) NOT-DE-21-001 NIDCR Jan 26, 2021 May 8, 2023 R01, R21
Notice of Special Interest (NOSI): Aging-Relevant Behavioral and Social Research on Coronavirus Disease 2019 (COVID-19) NOT-AG-21-015 NIA Jan 26, 2021 Sep 10, 2021 R01, R03, R21, U19, P01, R21/R33
Notice of Special Interest (NOSI): Leveraging Real-World Imaging Data for Artificial Intelligence-based Modeling and Early Detection of Abdominal Cancers NOT-CA-21-028 NCI Jan 25, 2021 Jan 8, 2024 R01
Notice of Special Interest: Promoting Research on COVID-19 and Rheumatic, Musculoskeletal and Skin Diseases NOT-AR-21-012 NIAMS Jan 5, 2021 Nov 19, 2021 R01, R21
Notice of Special Interest (NOSI): Leveraging Population-based Cancer Registry Data to Study Health Disparities NOT-CA-21-020 NCI Jan 4, 2021 May 8, 2023 R01, R21
Notice of Special Interest (NOSI): Adopting Techniques and Tools Developed from the BRAIN Initiative Toward NIMH Strategic Research Priorities NOT-MH-21-115 NIMH Dec 28, 2020 May 8, 2023 R01, R21, R15, P50
Notice of Special Interest (NOSI) for the NEI Anterior Segment Initiative (ASI): Identification and Development of New Biomarkers and Effective methods to Diagnose Dry Eye Disease. NOT-EY-21-007 NEI Dec 21, 2020 May 8, 2023 R01, R21, R43/R44, R41/R42
RESCINDED - Notice of Special Interest (NOSI): Research to Address Vaccine Hesitancy, Uptake, and Implementation among Populations that Experience Health Disparities NOT-MD-21-008 NIMHD NCI NHLBI NIAAA NIAID NIAMS NIDCR NIMH NINR OBSSR ODP ORWH Dec 17, 2020 Jan 8, 2022 R01
Notice of Special Interest (NOSI): Tailoring Follow-up Care for Survivors Using Risk-Stratified Pathways NOT-CA-21-019 NCI Dec 11, 2020 Feb 5, 2023 R01
Notice of Special Interest (NOSI): Advancing Genomic Technology Development for Research and Clinical Application NOT-HG-21-018 NHGRI Dec 4, 2020 Jan 10, 2024 R01, R21, R43/R44, R41/R42
Notice of Special Interest (NOSI): High-throughput Molecular and Cellular Phenotyping NOT-HG-21-004 NHGRI Dec 3, 2020 Jan 10, 2024 R01, R21
Notice of Special Interest: Advances in Research for the Treatment, Services, and Recovery of Alcohol Use Disorder NOT-AA-20-022 NIAAA Nov 27, 2020 Sep 8, 2023 R01, R03, R21
Notice of Special Interest (NOSI): Synthetic Biology for Biomedical Applications NOT-EB-20-017 NIBIB NCCIH NIGMS NICHD NCI NIA NIAID Nov 24, 2020 Jan 18, 2024 R01
RESCINDED - Notice of Special Interest (NOSI): Integrative Omics Analysis of NHLBI TOPMed Data (Parent R01 Clinical Trial Not Allowed) NOT-HL-20-823 NHLBI Nov 17, 2020 May 8, 2023 R01
NOSI: Academy of Finland (AKA) National Institutes of Health (NIH) Partnership Program NOT-OD-21-021 NIH NIAMS NIDDK NCI Nov 13, 2020 Jan 8, 2024 R01
Notice of Special Interest (NOSI): Use of Predictive Analytics to Accelerate Late-Stage Implementation Research to Address Heart, Lung, Blood, and Sleep Disorders NOT-HL-20-815 NHLBI Oct 26, 2020 Jan 8, 2024 R01
Notice of Special Interest: Integrative Studies of Neural Mechanisms Underlying Fundamental Affective Processes in Aging NOT-AG-21-012 NIA Oct 14, 2020 Jan 8, 2024 R21, R01
Notice of Special Interest (NOSI) Research on Rehabilitation Needs Associated with the COVID-19 Pandemic NOT-HD-20-031 NICHD Sep 29, 2020 May 8, 2023 R01, R03, R21
Notice of Special Interest (NOSI): Mechanisms of Mycobacterial-Induced Immunity in HIV-Infected and/or Uninfected Individuals to Inform Innovative Tuberculosis Vaccine Design NOT-AI-20-071 NIAID Sep 10, 2020 Jan 8, 2023 R01, R21
Notice of Special Interest (NOSI): Palliative Care in Heart, Lung, Blood, and Sleep Diseases NOT-HL-20-737 NHLBI Sep 9, 2020 Jul 6, 2023 R01
Notice of Special Interest (NOSI): Research in the Emergency Setting NOT-NS-20-005 NINDS NCI NIDA NHLBI NIDCD NIAAA NICHD NIA NIGMS NEI NIMHD NIMH Sep 8, 2020 Sep 8, 2022 R01, R21, R03, K01, K99/R00, K08, K23, R13, R43/R44, R41/R42, P01, U01, R34, R35, RM1
Notice of Special Interest: Optimizing Precision Treatment of Gynecologic, Reproductive and Obstetrical Outcomes in Adolescents and Adults with PCOS and Associated Comorbid Conditions (Clinical Trial Optional) NOT-HD-20-026 NICHD ORWH Sep 1, 2020 Sep 8, 2023 R01, R03
Notice of Special Interest: Emerging Viral Infections and their Impact on the Male and Female Reproductive Tract NOT-HD-20-021 NICHD ORWH Sep 1, 2020 Jul 16, 2023 R01, R21
Notice of Special Interest: Alcohol and Aging NOT-AA-20-019 NIAAA Aug 19, 2020 Sep 8, 2023 R01, R03, R21
Notice of Special Interest (NOSI): Simulation Modeling and Systems Science to Address Health Disparities NOT-MD-20-025 NIMHD NCI NIDA NLM ODP OBSSR NIMH NIAMS Aug 13, 2020 May 8, 2023 R01
Notice of Special Interest (NOSI): Comprehensive Care for Adults with Type 2 Diabetes Mellitus from Health Disparity Populations NOT-MD-20-026 NIMHD Aug 11, 2020 May 8, 2021 R01
Notice of Special Interest: Secondary Analyses of Existing Alcohol Research Data NOT-AA-20-018 NIAAA Aug 10, 2020 Sep 5, 2023 R01, R03, R21
Notice of Special Interest: Basic and Translational Research on Affective, Motivational, and Social Function in Normative Aging and/or Alzheimers Disease and Related Dementias (AD/ADRD) NOT-AG-20-040 NIA Aug 3, 2020 Jan 8, 2022 R01, R21
Notice of Special Interest: Fundamental and Translational Research on Decision Making in Aging and/or Alzheimers Disease and Alzheimers Disease Related Dementias (AD/ADRD) NOT-AG-20-039 NIA Jul 21, 2020 Jan 8, 2022 R01, R21
Notice of Special Interest (NOSI): Obesity Policy Evaluation Research (R01 Clinical Trial Not Allowed) NOT-DK-20-035 NIDDK OBSSR NCI NICHD ODP NHLBI Jul 13, 2020 Sep 8, 2023 R01
Notice of Special Interest: Epidemiology and Prevention in Alcohol Research NOT-AA-20-017 NIAAA Jul 13, 2020 Sep 8, 2023 R01, R21, R03
Notice of Special Interest: Research to Advance the Understanding and Management of the Multiple Organ Dysfunction Syndrome in Children (R01, R21) NOT-HD-20-019 NICHD Jul 1, 2020 Sep 8, 2022 R01, R21
Notice of Special Interest (NOSI): Utilizing Telemedicine or Other Remote-Based Platforms to Develop and Support Treatments for Substance Use Disorders NOT-DA-20-058 NIDA Jun 29, 2020 Jan 8, 2024 R01, R21
Notice of Special Interest (NOSI): Understanding Sudden Death in the Young Through Research NOT-HL-20-787 NHLBI NINDS Jun 29, 2020 Jan 8, 2023 R01
Notice of Special Interest (NOSI) in Research on Risk and Prevention of Black Youth Suicide NOT-MH-20-055 NIMH ODP NIMHD Jun 15, 2020 Jul 31, 2022 R01, R34
Notice of Special Interest (NOSI): Role of Astrocytes and Astrocytic Networks in Drug Abuse NOT-DA-20-060 NIDA Jun 8, 2020 Sep 8, 2023 R01, R21
Notice of Special Interest (NOSI) of NIDCR in Supporting Dental, Oral, and Craniofacial Research Using Bioinformatic, Computational, and Data Science Approaches NOT-DE-20-006 NIDCR Jun 5, 2020 Aug 8, 2023 R01, R21, R03, R41/R42, F99/K00, F30, F31, F32, F33, K01, K08, K23, K25, K22, K99/R00, K43, K18, R15, R43/R44
Notice of Special Interest (NOSI): NIDCD is Interested in Supporting Research on the Impact of COVID-19 on Mission Specific Sensory and Communication Disorders NOT-DC-20-008 NIDCD Jun 4, 2020 Sep 8, 2022 R01, R21, R41/R42, R43/R44
Notice of Special Interest (NOSI): Research on Co-morbid Substance Use, Substance Use Disorders, and Other Psychiatric Disorders NOT-DA-20-004 NIDA ORWH Jun 4, 2020 May 8, 2023 R34, R21, R03, R01
Notice of Special Interest (NOSI): Chimerism in Marmosets and other New World Primates NOT-MH-20-048 NIMH NIAID NINDS NIDA NIA Jun 3, 2020 Jan 8, 2022 R01, R21
Notice of Special Interest (NOSI): Improving Outcomes for Disorders of Human Communication NOT-DC-20-007 NIDCD May 22, 2020 Jan 10, 2022 R01, R21, U01, R43/R44, R41/R42
Notice of Special Interest (NOSI): Development and Preliminary Testing of Health-related Behavioral Interventions NOT-OD-20-106 OBSSR NIAMS NIMH NCCIH NIDA NIA NCI NIDCR NINR May 19, 2020 Sep 26, 2022 R01, R21, 333
Notice of Special Interest (NOSI): Advancing Research on SUD through Computational Neuroscience NOT-DA-20-022 NIDA May 5, 2020 Sep 8, 2023 R01, R21
RESCINDED - Notice of Special Interest (NOSI): Heart, lung, blood and sleep focused ancillary studies to large ongoing clinical trials NOT-HL-20-755 NHLBI Apr 29, 2020 May 8, 2022 R01
Notice of Special Interest (NOSI): Pulmonary Complications of Hematopoietic Stem Cell Transplantation in Childhood NOT-HL-20-761 NHLBI NICHD Apr 27, 2020 Sep 8, 2023 R01
Notice of Special Interest (NOSI): Cannabis, Prescription Opioid, or Prescription Benzodiazepine Drug Use Among Older Adults NOT-DA-20-014 NIDA Apr 22, 2020 Sep 8, 2023 R01, R03, R21
Notice of Special Interest: Promoting Research on Mechanisms of Pathogenesis and Pathophysiology of Atypical Femoral Fracture (AFF) and Osteonecrosis of the Jaw (ONJ) NOT-AR-21-006 NIAMS ORWH NIDCR NIA Apr 15, 2020 Jul 18, 2023 R01, R21
Notice of Special Interest (NOSI): Development of Biomedical Technologies for Coronavirus Disease 2019 (COVID-19) NOT-EB-20-007 NIBIB Apr 10, 2020 Aug 29, 2020 R01, R21, R03
Notice of Special Interest (NOSI): Single-Cell Proteomics for Interrogating Premalignant and Early Malignant Lesions NOT-CA-20-044 NCI Apr 9, 2020 May 8, 2023 R03, R21, R01, P01
Notice of Special Interest (NOSI): Neuroimmune Signaling and Function in Substance Use Disorders NOT-DA-20-046 NIDA Apr 7, 2020 Sep 8, 2023 R01, R21, R15, 333
RESCINDED - Notice of Special Interest (NOSI): Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Coronavirus Disease 2019 (COVID-19) NOT-AI-20-031 NIAID Mar 27, 2020 Apr 5, 2021 R03, R21, 333, R01, R43/R44, R41/R42
Notice of Special Interest: Health Services Research on Minority Health and Health Disparities (R01- Clinical Trial Optional) NOT-MD-20-011 NIMHD NIAAA NIDA OBSSR NCI NIDCR Mar 27, 2020 May 8, 2021 R01
Notice of Special Interest (NOSI): Exploring the Roles of Biomolecular Condensates (BMCs) in Substance Use Disorder and/or HIV-related processes NOT-DA-20-018 NIDA Mar 25, 2020 Sep 8, 2023 R01, R03, R21, 333
Notice of Special Interest (NOSI):Sleep and Substance Use Disorders NOT-DA-20-021 NIDA Mar 25, 2020 Sep 8, 2023 R01, R03, R21, K99/R00, R61/R33
Notice of Special Interest to Highlight High Priority Opportunities for Intervention Development Research in Geriatric Mental Health NOT-MH-20-027 NIMH Mar 19, 2020 Sep 8, 2023 R01, R21, R61/R33, R34
Notice of Special Interest: Alcohol and Cancer Control NOT-CA-20-034 NCI Mar 19, 2020 Sep 9, 2023 R01, R21, R03, 333
Notice of Special Interest (NOSI): Advancing Head and Neck Cancer Early Detection Research (AHEAD) NOT-CA-20-031 NCI NIDCR Mar 10, 2020 Jan 8, 2022 R03, R21, R01
Notice of Special Interest (NOSI): Human Molecular Genetics of Substance Use Disorders NOT-DA-20-030 NIDA Mar 5, 2020 Sep 8, 2023 R01, P50, P01
Notice of Special Interest (NOSI): Effects of Cannabis Use and Cannabinoids on the Developing Brain NOT-DA-20-039 NIDA Mar 5, 2020 Sep 8, 2023 R01, R03, R21
Notice of Special Interest (NOSI): Going Global: Using Gene Network Analyses to Understand the Etiology of SUD NOT-DA-20-020 NIDA Feb 26, 2020 Sep 8, 2023 R01, R03, R21, 333
Notice of Special Interest (NOSI): Research on Oral Anticancer Agents in the Contexts of Utilization, Adherence, and Health Care Delivery NOT-CA-20-026 NCI Feb 21, 2020 May 8, 2023 R01, R21, R03, P01
Notice of Special Interest (NOSI): The HIV-HCV-Substance Use Disorder Syndemic: Therapeutic Approaches NOT-DA-20-032 NIDA Feb 21, 2020 Sep 8, 2023 R01
Notice of Special Interest: Availability of Administrative Supplements to Promote Innovation in NCCIH Grants NOT-AT-20-004 NCCIH Feb 21, 2020 Jun 2, 2020 333, R01
Notice of Special Interest to Highlight Research Priorities for Risk Algorithms Applications in Healthcare Settings to Improve Suicide Prevention NOT-MH-20-031 NIMH Feb 14, 2020 Jan 8, 2022 R34, R01, R21, R03
Notice of Special Interest (NOSI): Drug-drug interactions among substances of abuse, medications to treat HIV infection, and pharmacotherapies to treat substance use disorders NOT-DA-20-013 NIDA Feb 6, 2020 May 8, 2022 R01, R03, R21
Notice of Special Interest (NOSI): Transcriptomic, epigenomic, regulatory RNA or functional genomic research in Substance Use Disorders NOT-DA-20-031 NIDA Feb 6, 2020 Jan 8, 2023 R01, R03, R21, 333, R21/R33
Notice of Special Interest (NOSI): Use of Biological "High" or "Medium" Priority AIDS Research on Non-AIDS-defining or AIDS-defining Cancers NOT-CA-20-022 NCI Jan 15, 2020 Jan 8, 2023 R01, R21, R03
Notice of Special Interest: Development of Statistical, Population Genetics and Computational Methods Related to Polygenic Prediction of Health and Disease in Diverse Populations NOT-HG-20-010 NHGRI NCI NHLBI Jan 13, 2020 Oct 5, 2023 R01, R21, R03
Notice of Special Interest (NOSI): Preclinical and Clinical Studies of the Interactions of Opioids and Stimulants NOT-DA-20-007 NIDA Jan 6, 2020 Jun 5, 2023 R03, R21, R01
Notice of Special Interest (NOSI): Biomarkers and Biotypes of Drug Addiction NOT-DA-20-012 NIDA Jan 6, 2020 May 7, 2023 R01
Notice of Special Interest (NOSI): De-implementation of Ineffective or Low-value Clinical Practices along the Cancer Care Continuum NOT-CA-20-021 NCI Jan 6, 2020 May 10, 2022 R01
Notice of Special Interest (NOSI): Modeling Social Contagion of Substance Use Epidemics NOT-DA-20-009 NIDA Jan 2, 2020 Jan 8, 2023 R01, R03, R21
Notice of Special Interest (NOSI): Technological Innovations for Advancing Clinical SPECT Imaging NOT-EB-19-022 NIBIB Dec 20, 2019 Jan 8, 2022 R01
Notice of Special Interest (NOSI): Competitive Supplements/Revisions (R01) Available for INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndromE) Project (Competitive Supplement/Revision Clinical Trial Optional) NOT-OD-20-023 NIH NIMH NCI NIEHS NIDCR NHLBI NICHD NIDCD NIAMS NINDS NIMHD NIA Dec 18, 2019 Sep 8, 2022 R01
Notice of Special Interest (NOSI): NIH Research Project Grants on Down Syndrome (R01) for the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project NOT-OD-20-025 NIH NIAID NICHD NIAMS NHLBI NIEHS NIDCR NIMHD NIDCD NIA NINDS NIMH NEI Dec 18, 2019 Jan 8, 2022 R01
Notice of Special Interest (NOSI): Advancing Development of Rapid Point-of-Care Hepatitis C Virus Diagnostics NOT-AI-20-013 NIAID NIBIB Dec 17, 2019 Jan 8, 2023 R43/R44, R41/R42, R21, R01
Notice of Special Interest (NOSI): Development of Functional Assay Sites to Evaluate Candidate -Omics Variants Associated with Heart, Lung, Blood, or Sleep Disease NOT-HL-19-731 NHLBI Dec 16, 2019 Jan 8, 2022 R01, R41/R42, R43/R44
Notice of Special Interest (NOSI): Addressing Health Disparities in NIDDK Diseases NOT-DK-20-003 NIDDK Dec 16, 2019 Jan 8, 2023 R01
Notice of Special Interest: Exploring the Mechanisms Underlying Analgesic Properties of Minor Cannabinoids and Terpenes NOT-AT-20-002 NCCIH Dec 13, 2019 Jan 8, 2022 R01, R21
Notice of Special Interest on Neurobehavioral Mechanisms of Social Isolation and Alcohol Use Disorder (AUD) NOT-AA-19-031 NIAAA Nov 12, 2019 Feb 8, 2022 R01
Notice of Special Interest: Advancing Research for Tickborne Diseases (TBDs) NOT-AI-20-005 NIAID NCCIH NIAMS NIMH NINDS Nov 12, 2019 Jan 8, 2023 R01, R41/R42, R43/R44, R15
Notice of Special Interest (NOSI): Biophysical and Biomechanical Aspects of Embryonic Development (R01) NOT-HD-19-037 NICHD Nov 5, 2019 Nov 8, 2022 R01
Notice of Special Interest (NOSI) of NIDCR in Supporting Discovery, Characterization, and Mechanistic Study of Genetic Variants Underlying Dental, Oral, and Craniofacial Diseases and Conditions NOT-DE-19-016 NIDCR Oct 29, 2019 Jan 8, 2022 R01
Notice of Special Interest (NOSI): Geospatial Approaches in Cancer Control and Population Sciences NOT-CA-20-004 NCI Oct 22, 2019 Jan 8, 2022 R01, R21
Notice of Special Interest: Promoting research opportunities on HIV/AIDS in NIAMS NOT-AR-20-005 NIAMS Oct 22, 2019 Jan 10, 2023 R01, R21, 333
Notice of Special Interest (NOSI): Epidemiologic Studies to Characterize Cardiovascular Health and its Predictors and Trajectories in Diverse Groups of Children NOT-HL-19-711 NHLBI Oct 9, 2019 Sep 8, 2022 R01
Notice of Special Interest: Understanding the biology of iodine nutrition, assessment, and outcomes in women, infants, and children (R01, R21, R03) NOT-HD-19-028 NICHD Oct 9, 2019 Sep 8, 2022 R01, R03, R21
Notice of Special Interest: Research on Emergency Medical Services for Children (EMSC) NOT-HD-19-022 NICHD Oct 9, 2019 Sep 8, 2022 R01, R03, R21
Notice of Special Interest (NOSI): Use of Biological Information to Understand How the Interplay of Environmental Exposures and Genes Influences Cancer Risk NOT-CA-20-002 NCI Oct 9, 2019 Jan 8, 2022 R01, R03, R21
Notice of Special Interest: Nutrigenetics and Nutrigenomics Approaches for Nutrition Research NOT-DK-19-019 NIDDK NCCIH Sep 25, 2019 Jan 8, 2022 R01
Notice of Special Interest: Research to Advance the Understanding and Management of the Multiple Organ Dysfunction Syndrome in Children (R01, R21) NOT-HD-19-023 NICHD Sep 20, 2019 Jan 8, 2022 R01, R21
Notice of Special Interest: Advancing the Understanding, Prevention, and Management of Infections Transmitted from Women to their Infants NOT-HD-19-021 NICHD Sep 20, 2019 Jan 8, 2022 R01, R21
Notice of Special Interest: High-Priority Research Topics for PA-19-053 and PA-19-056 NOT-AG-19-037 NIA NIAMS Sep 4, 2019 Jan 8, 2022 R21, R01
Notice of Special Interest: Mechanisms Underlying the Contribution of Sleep Disturbances to Pain NOT-HD-19-020 NICHD Sep 4, 2019 Sep 8, 2022 R01, R21
Notice of Special Interest: Research to Improve Pre-Pregnancy Care and Enhance Healthy Birth Intervals NOT-HD-19-019 NICHD Sep 4, 2019 Sep 8, 2022 R01, R03, R21
Notice of Special Interest in Ultrasound and Optics-based Devices for Trauma Care NOT-EB-19-016 NIBIB Aug 29, 2019 Jan 8, 2022 R01
Notice of Special Interest in Radiation Monitoring for Trauma Care NOT-EB-19-017 NIBIB Aug 29, 2019 Jan 8, 2022 R01
Notice of Special Interest in X-ray-based Devices for Trauma Care NOT-EB-19-015 NIBIB Aug 29, 2019 Jan 8, 2022 R01
Notice of Special Interest (NOSI): Epidemiology of Drug Abuse NOT-DA-19-066 NIDA Aug 29, 2019 Jan 8, 2022 R01, R21, R03, 333
Notice of Special Interest in Physiological Monitoring and Point of Care Technologies for Trauma Care NOT-EB-19-018 NIBIB Aug 29, 2019 Jan 8, 2022 R01
Notice of Special Interest (NOSI): IDEA2Health: Innovative Data Evaluation and Analysis to Health (Parent R01 Clinical Trial Not Allowed) NOT-HL-19-712 NHLBI Aug 15, 2019 Jan 8, 2022 R01
Notice of Special Interest (NOSI): Public Health Research on Cannabis NOT-DA-19-065 NIDA Aug 14, 2019 Jan 8, 2022 R01, R21, R03, 333
Notice of Special Interest: NCI's Research Interests to Improve Interprofessional Teamwork and Coordination During Cancer Diagnosis and Treatment NOT-CA-19-059 NCI Aug 8, 2019 Jan 8, 2022 R01, P01
Notice of Special Interest (NOSI): The Application of Big Data Analytics to Drug Abuse Research NOT-DA-19-041 NIDA Jul 12, 2019 Jan 8, 2022 R01, R21, R03
Notice of Special Interest (NOSI): Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R01, R21, R03) NOT-DA-19-037 NIDA Jul 11, 2019 Sep 8, 2022 R01, R21, R03
Notice of Special Interest (NOSI): Gene-Environment Interplay in Substance Use Disorders (R01, R21) NOT-DA-19-038 NIDA Jul 10, 2019 Jan 8, 2022 R01, R21
Notice of Special Interest (NOSI): Leveraging existing HIV observational cohorts to study HIV-associated HLBS disorders NOT-HL-19-705 NHLBI Jun 3, 2019 Jan 8, 2022 R01
Notice of Special Interest (NOSI): Understanding Factors in Infancy and Early Childhood (Birth to 24 months) That Influence Obesity Development NOT-HL-19-695 NHLBI May 21, 2019 May 25, 2020 R01
Notice of Special Interest to Highlight High Priority Research Opportunities on Suicide Prevention Crisis Services NOT-MH-19-025 NIMH Apr 23, 2019 Jan 8, 2022 R34, R01, R21, R03
Notice of Special Interest: Development of Cryogenic or Other Long-term Preservation and Revival Methods for Drosophila and Zebrafish Genetic Stocks NOT-OD-19-089 ORIP Mar 14, 2019 Jan 8, 2022 R01
Notice of Special Interest: SEARCH: Stimulating ExplorAtory Research on HIV/AIDS Contribution to Heart, Lung, Blood and Sleep Comorbidities (R01 - Clinical Trial Not Allowed) NOT-HL-19-677 NHLBI Mar 14, 2019 Jan 8, 2022 R01
Notice of Special Interest in Understanding Factors in Infancy and Early Childhood (Birth to 24 months) That Influence Obesity Development NOT-DK-19-007 NIDDK NICHD NIMHD OBSSR Jan 7, 2019 Jan 8, 2021 R01


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