Key Dates

Related Announcements

• July 12, 2023 - PHS 2023-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed). See NOFO PAR-23-230     
• July 12, 2023 – PHS 2023-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed). See NOFO PA-23-232         
• April 3, 2022 - NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed). See NOFO PAR-23-162       
• June 2, 2022 - PHS 2022-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed). See NOFO PA-22-176         
• June 2, 2022 - PHS 2022-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed). See NOFO PA-22-178         
• May 9, 2022 - Short-term Mentored Career Enhancement Award in Dental, Oral, and Craniofacial Research for Mid-Career and Senior Investigators (K18- Independent Clinical Trial Not Allowed). See NOFO PAR-22-121     
• April 21, 2022 - Fogarty HIV Research Training Program for Low-and Middle-Income Country Institutions (D43 Clinical Trial Optional). See NOFO PAR-22-151
• April 21, 2022 - Planning Grant for Fogarty HIV Research Training Program for Low- and Middle-Income Country Institutions (D71 Clinical Trial Not Allowed). See NOFO PAR-22-152     
• April 21, 2022 - Infrastructure Development Training Programs for Critical HIV Research at Low-and Middle-Income Country Institutions (G11 Clinical Trials Not Allowed). See NOFO PAR-22-153     
• February 11, 2022 - NIDCR Mentored Career Development Award to Promote Diversity (K01 Independent Clinical Trial Not Allowed). See NOFO PAR-22-050
• January 10, 2022 - NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed). See NOFO PAR-22-041     
• January 10, 2022 - NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22 Clinical Trial Not Allowed) . See NOFO PAR-22-044       
• January 10, 2022 - Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) . See NOFO PAR-22-060       
• September 8, 2021 - Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed). See NOFO PAR-21-252     
• August 17, 2021 - Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 Independent Clinical Trial Not Allowed). See NOFO PAR-21-271     
• August 17, 2021 - Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Institutionally-Focused Research Education Award to Promote Diversity (UE5 - Clinical Trial Not Allowed). See NOFO PAR-21-277
• May 19, 2021 - Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed). See NOFO PAR-21-155       
• April 21, 2021 - NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed). See NOFORFA-NS-21-012             
• March 18, 2021 - Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed). See NOFO PAR-21-169     
• March 18, 2021 - Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed). See NOFO PAR-21-173     
• February 10, 2021 - NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed). See NOFO  PA-21-151       
• February 8, 2021 - NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00 Independent Clinical Trial Not Allowed).  See NOFO PAR-21-060       
• January 14, 2021 - NIDCR Dual Degree Dentist Scientist Predoctoral to Postdoctoral Transition Award (F99/K00 Independent Clinical Trial Not Allowed).  See NOFO PAR-21-108       
• November 25, 2020 - NIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed). See NOFO PAR-21-084     
• October 28, 2020 - Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31-Diversity). See NOFO PA-21-052           
• October 26, 2020 - Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32). See NOFO PA-21-048       
• October 26, 2020 - Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30). See NOFO PA-21-049       
• October 26, 2020 - Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30). See NOFO PA-21-050       
• October 22, 2020 - Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33). See NOFO PA-21-047         
• October 21, 2020 - Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31). See NOFO PA-21-051
• May 12, 2020 - Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed). See NOFO PA-20-203       
• May 11, 2020 - Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed). See NOFO PA-20-205
• May 7, 2020 - Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed). See NOFO PA-20-190         
• May 7, 2020 - NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed). See NOFO PA-20-195
• May 7, 2020 - Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed). See NOFO PA-20-199       
• May 5, 2020 - NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed). See NOFO PA-20-185       
• May 5, 2020 - NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed). See NOFO PA-20-188             
• April 23, 2020 - Independent Scientist Award (Parent K02 - Independent Clinical Trial Not Allowed). See NOFO PA-20-174          

Issued by

National Institute of Dental and Craniofacial Research (NIDCR)

Purpose

This Notice of Special Interest (NOSI) calls for a variety of data science-oriented projects focused on developing and using data and data science resources, methods, and tools for dental, oral, and craniofacial (DOC) research. Investigators and trainees who are currently active in DOC, non-DOC, and disease agnostic data science spaces are strongly encouraged to apply. An application can respond to any Notice of Funding Opportunity (NOFO), and subsequent reissues, listed under Related Announcements seeking support for research, research training, career development, product development, or conferences. Overall, the initiative will promote research, research training, and career development projects that develop and use state of the art data science resources, methods, and tools in biomedical and behavioral DOC research spanning the full translational continuum from basic to clinical. In particular, applicants are strongly encouraged to develop and disseminate standards and tools to make retrospective and prospective biomedical and behavioral DOC data FAIR (findable, accessible, interoperable and reusable), use the data to discover disease prevention and treatment targets, and translate discoveries into evidence-based clinical applications.

Research and research training areas that this initiative is aimed to capture include, but are not limited, to the following:

• Maximizing the reuse of research, health, and clinical data, and enabling data-driven research by 1) making existing and new data FAIR, 2) making existing and new data AI/ML/DL-ready; and 3) developing Common Data Elements, ontological systems, natural language processing capabilities, and data analytics for DOC research.
• Integrating multiple data modalities to further improve diagnostic test efficacy, such as merging RNA sequence-based diagnostics into an AI/ML-powered clinical diagnostic pipeline to complement digital pathology slides-based diagnoses of head and neck cancer to better inform treatment planning.
• Integrating electronic dental and medical records to promote comprehensive, data-driven research and facilitate better-informed care and treatment planning.
• Developing deep-phenotyping, data curation, and data analysis web interfaces for clinicians to support clinical decision-making. For instance, an interface may have imaging and multi-omics data curation, and analysis functions for clinicians to use and inform treatment planning.
• Recruiting, curating, and analyzing health, ‘omic, behavioral, and social data obtained from multiple populations and age groups to understand oral health disparities and identifying prevention and intervention strategies for oral diseases and conditions such as dental caries.

 Application and Submission Information

This notice applies to due dates on or after January 1, 2024, and subsequent receipt dates through May 8, 2026.

Submit applications for this initiative using one of the following notice of funding opportunity (NOFO) or any reissues of these announcements through the expiration date of this notice.

• PA-20-174 - Independent Scientist Award (Parent K02 - Independent Clinical Trial Not Allowed)
• PA-20-185 - NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
• PA-20-188 - NIH Pathway to Independence Award (K99/R00 - Independent Clinical Trial Not Allowed)
• PA-20-190 - Mentored Research Scientist Development Award (K01 - Independent Clinical Trial Not Allowed)
• PA-20-195 - NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed)
• PA-20-199 - Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed)
• PA-20-203 - Mentored Clinical Scientist Research Career Development Award (K08 - Independent Clinical Trial Not Allowed)
• PA-20-205 - Mentored Patient-Oriented Research Career Development Award (K23 - Independent Clinical Trial Not Allowed)
• PA-21-047 - Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33)
• PA-21-048 - Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32)
• PA-21-049 - Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)
• PA-21-050 - Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)
• PA-21-051 - Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)
• PA-21-052 - Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31-Diversity)
• PA-21-151 - NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)
• PA-22-176 - PHS 2022-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
• PA-22-178 - PHS 2022-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)
• PAR-21-060 - NIDCR Predoctoral to Postdoctoral Transition Award for a Diverse Dental, Oral and Craniofacial Research Workforce (F99/K00 Independent Clinical Trial Not Allowed)
• PAR-21-084 - NIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed)
• PAR-21-108 - NIDCR Dual Degree Dentist Scientist Predoctoral to Postdoctoral Transition Award (F99/K00 Independent Clinical Trial Not Allowed)
• PAR-21-155 - Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)
• PAR-21-169 - Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed)
• PAR-21-173 - Support for Research Excellence – First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed)
• PAR-21-252 - Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)
• PAR-21-271 - Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 Independent Clinical Trial Not Allowed)
• PAR-21-277 - Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Institutionally-Focused Research Education Award to Promote Diversity (UE5 - Clinical Trial Not Allowed)
• PAR-22-041 - NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)
• PAR-22-044 - NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22 Clinical Trial Not Allowed)
• PAR-22-050 - NIDCR Mentored Career Development Award to Promote Diversity (K01 Independent Clinical Trial Not Allowed)
• PAR-22-060 - Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)
• PAR-22-121 - Short-term Mentored Career Enhancement Award in Dental, Oral, and Craniofacial Research for Mid-Career and Senior Investigators (K18- Independent Clinical Trial Not Allowed)
• PAR-22-151 - Fogarty HIV Research Training Program for Low-and Middle-Income Country Institutions (D43 Clinical Trial Optional)
• PAR-22-152 - Planning Grant for Fogarty HIV Research Training Program for Low- and Middle-Income Country Institutions (D71 Clinical Trial Not Allowed)
• PAR-22-153 - Infrastructure Development Training Programs for Critical HIV Research at Low-and Middle-Income Country Institutions (G11 Clinical Trials Not Allowed)
• PAR-23-162 - NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed)
• PAR-23-230 - PHS 2023-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed).
• PA-23-232 - PHS 2023-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed).
• RFA-NS-21-012 - NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed)

All instructions in the SF424 (R&R) Application Guide and the notice of funding opportunity used for submission must be followed, with the following additions:

• For funding consideration, applicants must include “NOT-DE-24-003” (without quotation marks) in the Agency Routing Identifier field (box 4B) of the SF424 R&R form. Applications without this information in box 4B will not be considered for this initiative.

Applications nonresponsive to terms of this NOSI will not be considered for the NOSI initiative.

Inquiries

Please direct all inquiries to the contacts in Section VII of the listed notice of funding opportunity with the following additions/substitutions:

Scientific/Research Contact(s)

Noffisat O. Oki, Ph.D.
National Institute of Dental and Craniofacial Research (NIDCR)
Telephone: 301-402-6778
Email: [email protected]