Notice Number: NOT-DA-19-041
Release Date: July 12, 2019
First Available Due Date: October 5, 2019
Expiration Date: January 8, 2022
PA-19-056: NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
PA-19-055: NIH Research Project Grant (Parent R01 Clinical Trial Required)
PA-19-091: Research Project Grant (Parent R01 Clinical Trial Required)
PA-19-052: NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)
PA-19-092: NIH Exploratory/Developmental Research Grant Program (Parent R21 Basic Experimental Studies with Humans Required)
PA-19-053: NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed)
PA-19-054: NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Required)
National Institute on Drug Abuse (NIDA)
The purpose of this Notice is to inform potential applications to the National Institute on Drug Abuse (NIDA) to encourage grant applications that will use ‘big data’ analytics to reveal deeper or novel insights into the biological and behavioral processes associated with substance use and addiction by developing more powerful analytical methods and visualization tools that can help capture the richness of different data types and across scales of analysis; including molecular, clinical, and electronic health records. Applications should develop and/or utilize computational approaches for analyzing large, complex datasets acquired from drug addiction research.
National investments in basic research are poised to accelerate discoveries in neuroscience, genetics, and health service research. Additionally, a shift in culture is promoting open access and data sharing to allow diverse data sets to be broadly accessible to researchers. Advances in information technologies and analytics capabilities are producing extraordinary capacity and opportunity to integrate and analyze these data, thereby enabling novel research into complex disorders such as drug abuse and addiction that are driven by the dynamic interactions of diverse biological, social, organizational, environmental, and behavioral mediators. The result is an emerging era of research with unique opportunities to leverage volumes of data in new ways and turning vast datasets of complex information into the next discoveries.
NIDA is interested in harnessing big data analytics to gain new knowledge related to the neurobiological and behavioral changes that are consequences of, or that underlie, drug use and addiction. Analyses may involve one or more data sets or knowledge sources but should address fundamental research questions associated with substance abuse research and also develop computational tools (e.g., aggregated datasets, standards, analytic software) facilitating future analysis of substance abuse research data. Primary data may be of multiple types and formats, and available through sources which include, but are not limited to, large databases and repositories of existing data, publicly available information (e.g., Twitter data), images, videos, and EHR records.
Examples of approaches that are encouraged include, but are not limited to:
Areas of programmatic interest to NIDA include:
Application and Submission Information:
This notice applies to due dates on or after October 5, 2019 and subsequent receipt dates through January 8, 2022.
Submit applications for this initiative using one of the following funding opportunity announcements (FOAs) or any reissues of these announcement through the expiration date of this notice.
All instructions in the SF424 (R&R) Application Guide and the funding opportunity announcement used for submission must be followed, with the following additions:
Applications nonresponsive to terms of this NOSI will be not be considered for the NOSI initiative.
Please direct all inquiries to: