Notice Number: NOT-DA-19-037

Key Dates
Release Date: July 11, 2019
First Available Due Date: October 5, 2019
Expiration Date: September 8, 2022.

PA-19-056: NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)

PA-19-055: NIH Research Project Grant (Parent R01 Clinical Trial Required)

PA-19-091: NIH Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required)

PA-19-052: NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)

PA-19-092: NIH Exploratory/Developmental Research Grant Program (Parent R21 Basic Experimental Studies with Humans Required)

PA-19-053: NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed)

PA-19-054: NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Required)

Issued by
National Institute on Drug Abuse (NIDA)

Purpose

The purpose of this Notice is to inform potential applications to the National Institute on Drug Abuse (NIDA) of special interest in grant applications to conduct rigorous health services and economic research to maximize the availability and delivery of efficient, effective drug, alcohol, and tobacco treatment and recovery support services. Examples of such research include: (1) clinical quality improvement; (2) quality improvement in services organization and management; (3) implementation science; (4) availability, demand, access, and financing; (5) effectiveness; and (6) development or improvement of research methodology, analytic approaches, and measurement instrumentation.

Background

Although efficacious addiction treatment approaches exist, too few patients with drug, alcohol, and tobacco use disorders receive them in a timely manner or for a sufficient duration. At the same time, clinical, administrative, and financing policies and practices have been deployed without a sufficient evidence base, often resulting in barriers to high-quality care. As addiction treatment expands into additional settings, research is needed to promote the availability of effective treatment when and where patients need it, for as long as they need it.

Research Objectives

NIDA seeks research on rigorous hypothesis-driven and theory-based study designs and data analytic methods that will support a new generation of addiction health services research. This NOSI encourages, but is not limited to, applications in the following areas:

• Clinical quality improvement studies to examine factors that may improve the appropriateness, effectiveness, safety, and efficiency of treatment and recovery interventions, as well as services delivered to individuals, including vulnerable populations, individuals experiencing chronic pain, sex and gender minorities, and racial and ethnic minorities, in a variety of settings including substance abuse and mental health treatment programs, schools, general health care settings, criminal and juvenile justice systems, child welfare systems and social service agencies.
• Quality improvement studies in services organization and management studies that address organizational contexts and service delivery models, the interaction of providers and programs within and across systems, and at multiple levels (e.g., program, practice network, state), and their collective impact on the quality of service delivery.
• Implementation science studies that seek to identify effective strategies for enhancing the adoption, adaptation, and sustainment of evidence-based treatment practices. Studies that examine causal models of implementation success or failure are especially encouraged.
• Studies examining the effects of practice and policy changes on service quality and outcomes, including unintended consequences.
• Economic studies falling within NIH’s priorities for health economics research as described in NOT-OD-16-025.
• Studies developing or applying new methods, analytic techniques or approaches (e.g., modeling), technologies or other innovative tools to improve the rigor and reach of health services research.

Application and Submission Information

This notice applies to due dates on or after October 5, 2019 and subsequent receipt dates through September 8, 2022.

Submit applications for this initiative using one of the following funding opportunity announcements (FOAs) or any reissues of these announcement through the expiration date of this notice.

Applications in response to this Notice must be submitted through NIH Parent Announcement

PA-19-056: NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)

PA-19-055: NIH Research Project Grant (Parent R01 Clinical Trial Required)

PA-19-091: NIH Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required)

PA-19-052: NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)

PA-19-092: NIH Exploratory/Developmental Research Grant Program (Parent R21 Basic Experimental Studies with Humans Required)

PA-19-053: NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed)

PA-19-054: NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Required)

All instructions in the SF424 (R&R) Application Guide and the funding opportunity announcement used for submission must be followed, with the following additions:

• For funding consideration, applicants must include "NOT-DA-19-037" (without quotation marks) in the Agency Routing Identifier field (box 4B) of the SF424 R&R form.

Applications nonresponsive to terms of this NOSI will be not be considered for the NOSI initiative.

Inquiries

Please direct all inquiries to:

Tisha Wiley, Ph.D.
National Institute on Drug Abuse (NIDA)
Telephone: (301) 594-4381
Email: [email protected]