February 9, 2023
PA-20-185 - NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
PA-20-183 - Research Project Grant (Parent R01 Clinical Trial Required)
PA-20-184 - Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required)
PA-20-200 - NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)
PA-21-221 - NICHD Small Research Grant Program (R03 Clinical Trial Required)
PA-21-231 - NICHD Small Research Grant Program (R03 Basic Experimental Studies with Humans Required)
PA-20-194 - NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Required)
PA-20-195 - NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed)
PA-20-196 - NIH Exploratory/Developmental Research Grant Program (Parent R21 Basic Experimental Studies with Humans Required)
The purpose of this Notice of Special Interest (NOSI) is to encourage research on the processes that facilitate or hinder the achievement of healthy interbirth intervals and promote healthy birth outcomes. Because short interbirth intervals are associated with a range of risk factors and poor maternal and child health outcomes, reducing the proportion of pregnancies conceived within 18 months of a previous pregnancy is a Healthy People 2030 objective. These negative outcomes include a lack of preconception health care, delayed prenatal care, preeclampsia, prematurity, low birth weight, infant mortality, and maternal morbidity and mortality. Short interbirth intervals may also reduce the duration of breastfeeding; conversely, the continuation of breastfeeding can contribute to the lengthening of interbirth intervals. This NOSI is intended to encourage collaboration among researchers across the social, behavioral, biomedical, and public health sciences to elucidate understanding of the modifiable factors behind barriers to enhancing birth intervals.
This NOSI invites research applications that assess the causal social and behavioral processes that facilitate or hinder the achievement of healthy interbirth intervals and to identify mechanisms that can be modified by public health interventions at the levels of the dyad, family, community, or other population aggregates. The failure to achieve a healthy birth interval is defined as the behavioral health outcome wherein sexually active, reproductively capable individuals or couples who do not desire a pregnancy fail to consistently and effectively use available prevention techniques. This NOSI encourages cross-disciplinary and multi-level studies, domestic and international study sites, and research focused on understudied and vulnerable populations, including persons with disabilities. Studies of how social and economic structural-level factors influence the achievement of healthy birth intervals are of particular interest. Applications that propose secondary analyses of existing data from randomized control trials, natural experiments, or public health interventions are welcomed, as are proposals that would help improve or assess future clinical trials. Proposals responding to this NOSI should be theoretically grounded and use highly specified conceptual models. Descriptive analyses of the epidemiology of unintended pregnancy are not within the scope of this Notice. Potential applicants are encouraged to contact program staff named in this NOSI to discuss the relevance of their proposals.
Topics of interest include but are not limited to:
Systems and contextual factors that hinder or facilitate the achievement of healthy birth intervals:
Individual, dyadic, or familial aspects of the achievement of healthy birth intervals:
Application and Submission Information
This notice applies to due dates on or after June 5, 2023 and subsequent receipt dates through May 8, 2024.
Submit applications for this initiative using one of the following funding opportunity announcements (FOAs) or any reissues of these announcement through the expiration date of this notice.
All instructions in the SF424 (R&R) Application Guide and the funding opportunity announcement used for submission must be followed, with the following additions:
Applications nonresponsive to terms of this NOSI will not be considered for the NOSI initiative.
Ronna Popkin, PhD
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Elena Gorodetsky, M.D., Ph.D.
Office of Research on Women’s Health (ORWH)