By accepting a grant award, recipients agree to comply with the requirements in the NIH Grants Policy Statement unless the notice of award states otherwise. Specific policy topic pages listed below expand upon this resource to provide additional context and resources.
The National Institutes of Health Grants Policy Statement (NIHGPS) makes available, in a single document, the policy requirements that serve as the terms and conditions of NIH grant awards.
Notices published in the NIH Guide for Grants and Contracts can supersede information in the NIH Grants Policy Statement and/or provide reminders to applicants and recipients. NIH incorporates these notices into the annual update of the NIH Grants Policy Statement.
Federal requirements, guidelines and resources for the extramural community involving grants compliance. The information provided on this website is designed to assist the extramural community in understanding the compliance obligations of their grant award, and understand the proper use of grant funds.
NIH and the biomedical research enterprise have a long history of International collaborations with rules of engagement that allow science to advance while also protecting intellectual capital and proprietary information of the participating countries. These rules of engagement also are designed to limit bias in the design, conduct, and reporting of NIH-supported research. Learn more about actions that NIH, institutions, and researchers can take to protect U.S. biomedical intellectual innovation.
The Office of Laboratory Animal Welfare ensures the humane care and use of animals in PHS-supported research, testing, and training by providing guidance and interpretation of the Public Health Service Policy on Humane Care and Use of Laboratory Animals, supporting educational programs, and monitoring compliance with the policy.
Learn about the policies that may impact your application submission, including late applications, due dates on holidays/weekends, post submission application materials, continuous submission, guidelines for applicants experiencing system issues, resubmission policies, overlapping applications, weather and other disasters, and more.
Publicizing the outcomes of NIH-funded projects and communicating the role of NIH support in biomedical research improves public understanding of how we, the biomedical research community as a whole, are working to improve human health. This important information for researchers and public information officers (PIOs) describes how to correctly acknowledge NIH in your presentations, papers, posters, and press releases.
If you are submitting a grant application or responding to a contract proposal to NIH that includes a clinical trial, or are involved with conducting, managing, or overseeing clinical trials, learn about NIH policies, and find resources to guide you in your work.
NIH is committed to the continued support of early stage investigators; they bring fresh ideas and pioneer new areas of investigation. NIH has a number of policies and programs to encourage the support of these populations. Learn about these policies and whether you might qualify as an early stage investigator.
Find useful information about proposing and conducting NIH extramural research involving human subjects, including policies, regulations, training and resources. Learn about considerations for human subjects research when planning and submitting a research application or contract proposal, and throughout the extramural funding cycle.
NIH is committed to supporting clinical research that benefits individuals of all sexes/genders, races, ethnicities, and ages. The information provided on this website is designed to assist the extramural community in addressing inclusion, including the Inclusion of Women and Minorities policy and the Inclusion Across the Lifespan policy, in NIH grant applications and progress reports.
Inventions arising from federally funded research are required to be reported to the government agency that funded the project. Learn about the systems and policies related to intellectual property and invention reporting.
A general overview of lobbying restrictions on the work of NIH recipients, along with examples of restricted and permissible activities.
In emergency situations, the NIH’s immediate concern is for the health and safety of people and animals in the programs we oversee. We are also deeply concerned about the health of the biomedical enterprise in the affected area, and we are committed to working with researchers and institutions to do all that we can to ensure that NIH-funded research continues.
Learn about the NIH budget process, grant funding strategies for each NIH Institute and Center, and more.
Learn about the regulations and processes that govern peer review, including management of conflicts of interest, applicant and reviewer responsibilities in maintaining the integrity in peer review, appeals, and more.
The NIH public access policy requires scientists to submit final peer-reviewed journal manuscripts that arise from NIH funds to PubMed Central immediately upon acceptance for publication. Learn how to address copyright issues, post manuscripts that have been accepted for publication to PubMed Central, and include the PMCID in citations in compliance with the policy.
Learn about research integrity, responsible conduct of research, and research misconduct, including related policies and regulations, and what you can do to promote research integrity.
Key to the successful application of knowledge toward health outcomes is scientific rigor in conducting biomedical research. NIH promotes the highest level of scientific integrity, public accountability, and social responsibility in the conduct of science. This page assists the research community in addressing rigor and reproducibility in their grant applications.
Learn about NIH's commitment to supporting a safe and respectful work environment, who to contact with questions or concerns, and what NIH's expectations are for institutions and the individuals supported on NIH-funded awards.
NIH expects recipients to make the results and accomplishments of their activities available to the research community and to the public at large. This site highlights NIH policies and guidance on sharing of research resources developed with NIH funding.