PA-20-183 - Research Project Grant (Parent R01 Clinical Trial Required) is used for the submission of applications to the following Notices of Special Interest (NOSIs)

On This Page: 133

Active NOSIs
Expired NOSIs

Active NOSIs

Title	Notice Number	Organization	Release Date	Expiration Date	Activity Code(s)
Notice of Special Interest (NOSI): Studies of Cellular/Molecular Pathobiological Mechanisms of Lung Diseases Using Human 3-Dimensional Cellular Systems (R01)	NOT-HL-22-030	NHLBI	Jul 5, 2022	Sep 8, 2025	R01
Notice of Special Interest (NOSI): Stimulating Research to Understand and Address Hunger, Food and Nutrition Insecurity	NOT-OD-22-135	ONR , FIC , NCI , NHLBI , NIAMS , NICHD , NIDCR , NIDDK , NIMH , NIMHD , NINR , OAR , OBSSR , ODP , ODS , PN , ORWH	Jun 21, 2022	Nov 29, 2024	R01, 333, R21, K01, R34, R33, R61/R33, UG3/UH3, K43
Notice of Special Interest (NOSI): Preventive Interventions to Address Cardiometabolic Risk Factors in Populations that Experience Health Disparities	NOT-OD-22-154	ODP , NCI , NHLBI , NIAAA , NIAMS , NIDCR , NIEHS , NIMHD , NINDS , OBSSR , ORWH	Jun 14, 2022	Oct 6, 2025	R01, R21, R34, R03, UG3/UH3
Notice of Special Interest (NOSI): Research to Support Regulatory Science on Infant Formula	NOT-HD-22-016	NICHD , OD , ODS	Jun 13, 2022	May 8, 2023	R03, R41/R42, R43/R44, R01, 333, R21
Notice of Special Interest (NOSI): Climate Change and Health	NOT-ES-22-006	NIEHS , FIC , NCI , NHGRI , NHLBI , NIA , NIAID , NIAMS , NICHD , NIDCR , NIMH , NIMHD , NINDS , NINR , NLM , ODP	Jun 1, 2022	May 8, 2025	R21, F31, D43, K01, R03, K43, K99/R00, U01, U19, R01, F32, K23, F30, R21/R33
Notice of Special Interest (NOSI): NIH Research Project Grants on Down Syndrome (R01) for the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project	NOT-OD-22-123	OD , NCI , NEI , NHLBI , NIA , NIAMS , NICHD , NIDCD , NIDCR , NIMHD , NINDS	May 26, 2022	May 1, 2025	R01
Notice of Special Interest: Disease Mechanisms of Prenatal and Pediatric Hydrocephalus	NOT-NS-23-004	NINDS	May 20, 2022	Dec 10, 2025	R01
Notice of Special Interest: Tools to Enhance the Study of Prenatal and Pediatric Hydrocephalus	NOT-NS-23-003	NINDS	May 20, 2022	Dec 10, 2025	R21, R01
Notice of Special Interest (NOSI): Increasing Uptake of Evidence-Based Screening in Diverse Populations Across the Lifespan	NOT-OD-22-106	ODP , NCI , NIA , NIAAA , NIAMS , NICHD , NIDA , NIDCD , NIDCR , NIMH , NIMHD , NINDS , NINR , ODS , ORWH , SGMRO	May 12, 2022	May 8, 2025	R03, R01, R34, R21, UG3/UH3, R61/R33, 333
Notice of Special Interest (NOSI): Addressing Evidence Gaps in Screening	NOT-OD-22-107	ODP , NIA , NIAAA , NIAMS , NICHD , NIDA , NIDCD , NIDCR , NIMH , NIMHD , NINDS , NINR , ODS , ORWH , SGMRO	May 12, 2022	May 8, 2025	333, R01, R34, R21, R61/R33, U01, UG3/UH3
Notice of Special Interest (NOSI): IMPROVE Initiative: Implementation Science to Advance Maternal Health and Maternal Health Equity	NOT-OD-22-125	OD	May 5, 2022	Jul 17, 2022	R01, R03, R21
Notice of Special Interest: Research on Alcohol and Coronavirus Disease (COVID-19) within the Mission of NIAAA	NOT-AA-22-012	NIAAA	Apr 29, 2022	Mar 6, 2024	R01, R03, R21, K99/R00
Notices of Special Interest (NOSI): High Priority Areas in Genetics, Epigenetics, and Developmental Neuroscience Branch in the Division of Neuroscience and Behavior	NOT-DA-23-004	NIDA	Apr 14, 2022	Sep 9, 2025	R01
Notice of Special Interest (NOSI) - Emerging and Existing Issues of Coronavirus Disease 2019 (COVID-19) Research Related to the Health and Well-Being of Women, Children and Individuals with Physical and/or Intellectual Disabilities	NOT-HD-22-002	NICHD , NIDA , NIEHS , NINDS , OBSSR , ORWH	Mar 28, 2022	Jun 6, 2024	R01, R21
Notice of Special Interest (NOSI): Research using implementation science to support the delivery of evidence-based practices in community-based mental or general medical healthcare settings	NOT-MH-22-170	NIMH , NIDA	Mar 25, 2022	May 8, 2025	R21, R01, R34
Notice of Special Interest (NOSI): Technological Innovations for Advancing Clinical SPECT Imaging	NOT-EB-22-006	NIBIB	Mar 21, 2022	May 8, 2024	R21, F30, K01, R13, K23, K25, R43/R44, K08, R01, K99/R00, R41/R42, F32, R03, F31
Notice of Special Interest (NOSI): Leveraging Data Science to Bring Actionable Insights for Substance Use Prevention and Treatment	NOT-DA-23-006	NIDA	Mar 1, 2022	Sep 8, 2025	R21, R01, R03, 333
Notice of Special Interest (NOSI): Epidemiology of Drug Abuse	NOT-DA-22-004	NIDA	Feb 23, 2022	Sep 8, 2025	R21, R01, 333, R03
Notice of Special Interest (NOSI): Public Health Research on Cannabis	NOT-DA-22-003	NIDA	Feb 18, 2022	May 5, 2025	R21, R01, 333, R03
Notice of Special Interest (NOSI): Research on Drowning Prevention	NOT-HD-21-048	NICHD , NIMHD , ODP	Feb 15, 2022	May 8, 2024	R01, K23, K08, K99/R00, R21, R03
Notice of Special Interest (NOSI): Priority Research Opportunities in Crisis Response Services	NOT-MH-22-110	NIMH , NIDA , ORWH	Feb 8, 2022	May 8, 2025	R21, R01, R34, R43/R44
Notice of Special Interest (NOSI): Validation of Digital Health and Artificial Intelligence Tools for Improved Assessment in Epidemiological, Clinical, and Intervention Research	NOT-CA-22-037	NCI , NHLBI , NIA , NIDA , NIMH , NINR , OBSSR	Jan 27, 2022	Mar 9, 2024	R01, R03, R21, R43/R44, R41/R42, R33, R34, R61/R33
Notice of Special Interest (NOSI): Research to Prevent Drug Use, Misuse and Addiction	NOT-DA-23-001	NIDA , ODP	Jan 21, 2022	May 8, 2025	R01, R21, R34, R03
Notice of Special Interest (NOSI): Disparities Affecting Healthcare Utilization and Health Outcomes Among Childhood Cancer Survivors	NOT-CA-22-029	NCI	Jan 7, 2022	Oct 9, 2024	R01, R21, P01, R03
Notice of Special Interest: Development and Implementation of Clinical Informatics Tools to Enhance Patients Use of Genomic Information	NOT-HG-22-011	NHGRI	Jan 6, 2022	Dec 31, 2025	R01, R21, U24, R43/R44, R41/R42
Notice of Special Interest (NOSI): Advancing Innovative Non-invasive Physiologic Monitoring To Improve Fetal Assessment	NOT-HD-21-053	NICHD	Dec 28, 2021	May 8, 2024	R03, R01, R41/R42, R43/R44, R21
Notice of Special Interest: Research on Pain, Pain Management, and Opioids in Aging	NOT-AG-22-004	NIA	Dec 22, 2021	Jan 8, 2025	F31, P01, K99/R00, K08, R01, K01, R43/R44, F32, 332, F33, F99/K00, R15, K24, R21, K02, K25, R25, F30, K23, R36, R41/R42, SB1, K76, K22, K07, R13, R21/R33, U19
Notice of Special Interest (NOSI): Promoting Fundamental Research on Mitochondrial Involvement in Lung Diseases and Sleep Disorders	NOT-HL-22-003	NHLBI	Dec 22, 2021	Apr 5, 2025	R01
Notice of Special Interest (NOSI): Research to Address Vaccine Hesitancy, Uptake, and Implementation among Populations that Experience Health Disparities	NOT-MD-22-006	NIMHD , ODP , NIDA , NIAID , SGMRO , NIMH , ORWH , NINR , NCI , NIDCR , OBSSR	Dec 21, 2021	Jan 8, 2023	R01
Notice of Special Interest (NOSI): Electronic Nicotine Delivery Systems (ENDS) and Alternative Nicotine and Tobacco Delivery Systems: Basic Mechanisms of Health Effects	NOT-OD-22-022	ODP , NIDCR , NCI , NIEHS , NIDA	Dec 9, 2021	May 9, 2023	R01, R61/R33, R21, 333, R03
Notice of Special Interest (NOSI): Epidemiology and Prevention of Alcohol Misuse in Understudied Young Adult Populations; Military, Workforce, and Community College	NOT-AA-22-001	NIAAA	Dec 9, 2021	Sep 9, 2025	R21, R03, R01, R43/R44, R41/R42
Notice of Special Interest (NOSI): Electronic Nicotine Delivery Systems (ENDS) and Alternative Nicotine and Tobacco Delivery Systems: Population, Clinical and Applied Prevention Mechanisms of Health Effects	NOT-OD-22-023	ODP , NCI , NIDA , NIMHD , NIDCR	Dec 8, 2021	May 9, 2024	R21, R01, 333, R34, R03, R61/R33
Notice of Special Interest (NOSI): Examining Effects of HIV Pre-Exposure Prophylaxis (PrEP) on Heart, Lung, Blood, and Sleep Function	NOT-HL-21-025	NHLBI	Nov 24, 2021	May 5, 2024	R01
Notice of Special Interest (NOSI): Accelerating Progress in Celiac Disease Research	NOT-AI-22-004	NIAID , NIAMS , NCCIH , NCI	Nov 23, 2021	Jan 8, 2025	R03, R21, U01, U44, R01, R34, P01, R61/R33
Notice of Special Interest (NOSI): Reducing Stigma Related to Drug Use in Human Service Settings	NOT-DA-21-060	NIDA , NIMH	Nov 18, 2021	Jan 8, 2025	R34, R01, DP1, DP2
Notice of Special Interest (NOSI): Heart, Lung, Blood and Sleep Focused Ancillary Studies to Large Ongoing Clinical Studies (Revised)	NOT-HL-21-030	NHLBI	Nov 8, 2021	May 8, 2023	R01
Notice of Special Interest (NOSI): Improving Outcomes in Cancer Treatment-Related Cardiotoxicity	NOT-CA-22-001	NCI , NHLBI	Nov 4, 2021	Nov 6, 2024	R01, R03, R21, P01
Notice of Special Interest (NOSI): IDEA2Health: Innovative Data Evaluation and Analysis to Health	NOT-HL-22-001	NHLBI	Oct 26, 2021	Jan 8, 2025	R01
Notice of Special Interest (NOSI): Promoting research to understand vascular contributions to cognitive impairment and dementia (VCID)	NOT-HL-23-002	NHLBI , NINDS , NIA	Oct 14, 2021	May 8, 2025	R01
Notice of Special Interest (NOSI): Promoting Pain Research Within the NIAMS Mission Areas	NOT-AR-22-007	NIAMS	Sep 23, 2021	Jan 10, 2023	R01, R21, R15, R33, R13, R34, K99/R00, K24, K01, K25, K23, K08, 332
Notice of Special Interest (NOSI): Evaluation of sex differences on HIV-associated comorbidities in the context of stimulant use	NOT-DA-21-020	NIDA	Sep 9, 2021	Jan 8, 2025	R01
Notice of Special Interest (NOSI): Promoting Cardiovascular and Cardiometabolic Health in Early Stages of the Lifecourse: Pre-adolescence Through Adolescence to Young Adulthood	NOT-HL-21-015	NHLBI	Aug 30, 2021	Jun 6, 2026	R01
Notice of Special Interest (NOSI): Social, Behavioral, and Economic Impact of COVID-19 in Underserved and Vulnerable Populations	NOT-MH-21-330	NIMH , NEI , ODP , SGMRO , NIDA , OBSSR , NIAAA , NINR , NIDCR , NIMHD , ORWH , NICHD , NIDCD , NIA , NCCIH	Aug 20, 2021	Sep 8, 2024	R01, UG3/UH3
Notice of Special Interest (NOSI): International Research Collaboration on Drug Abuse and Addiction Research	NOT-DA-21-064	NIDA	Aug 12, 2021	Sep 8, 2024	R01, R03, R21, 333
RESCINDED - Notice of Special Interest (NOSI): International Research Collaboration on Drug Abuse and Addiction Research	NOT-DA-21-002	NIDA	Jul 14, 2021	Sep 8, 2024	R01, 333, R03, R21
Notice of Special Interest (NOSI): Electronic Nicotine Delivery Systems (ENDS) and Alternative Nicotine and Tobacco Delivery Systems: Basic Mechanisms of Health Effects	NOT-OD-21-127	ODP , NIEHS , NIDCR , NIDA , NCI	Jun 28, 2021	May 8, 2023	333, R03, R01, R21
Notice of Special Interest (NOSI): Advancing HIV/AIDS Research through Computational Neuroscience	NOT-DA-21-030	NIDA	Jun 22, 2021	Jan 8, 2025	R01, R21, R03, DP2, DP1, K99/R00, K01, R36, P01, R15, K24
Notice of Special Interest (NOSI): Navigating Pediatric to Adult Health Care: Lost in Transition	NOT-HD-21-027	NICHD , NIAAA , NCI , NIMH , NIAMS , OBSSR , NIBIB , NIDCR	Jun 22, 2021	Jan 8, 2024	R01, R21, R43/R44, R41/R42
Notice of Special Interest (NOSI): Reduction of Sudden Unexpected Infant Death and Sudden Infant Death Syndrome	NOT-HD-21-032	NICHD	May 26, 2021	May 8, 2023	R01, R03, R21
Notice of Special Interest: Advanced Computational Approaches to Elucidate Disease Pathology and Identify Novel Therapeutics for Addiction	NOT-DA-21-004	NIDA	May 17, 2021	Jan 8, 2025	R01
Notice of Special Interest: Public Policy Effects on Alcohol-, Cannabis-, Tobacco-, and Other Drug-Related Behaviors and Outcomes	NOT-AA-21-028	NIAAA , NIDA , NCI	May 5, 2021	Sep 8, 2024	R01, R03, R21
RESCINDED - Notice of Special Interest (NOSI): NIH Research Project Grant (R01) Applications from Individuals from Diverse Backgrounds, Including Under-Represented Minorities	NOT-NS-21-049	NINDS , NIAAA , NIDA	May 3, 2021	May 8, 2023	R01
Notice of Special Interest (NOSI): Research on the Impact of the Covid 19 Pandemic and Risks for Abuse and Injury Among Vulnerable Children and Youth	NOT-HD-21-026	NICHD , SGMRO	Apr 27, 2021	May 8, 2024	R01, R03, R21, K22, R25
Notice of Special Interest (NOSI): Reproductive Health, Pregnancy, and Parenting among Women with Disabilities	NOT-HD-21-025	NICHD	Apr 27, 2021	May 31, 2024	R01, R03
Notice of Special Interest (NOSI): Women and Sex/Gender Differences in Drug and Alcohol Abuse/Dependence	NOT-DA-21-012	NIDA , NIAAA , ORWH , SGMRO	Apr 23, 2021	Sep 8, 2024	R01, R03, R21
Notice of Special Interest (NOSI): Research on Strategies to Enhance Mental Health Interventions and Services within Employment and Job Training Settings	NOT-MH-21-230	NIMH , NIDA	Apr 16, 2021	Sep 8, 2023	R01, R34, R43/R44, R21
Notice of Special Interest (NOSI): Improving Patient Adherence to Treatment and Prevention Regimens to Promote Health	NOT-OD-21-100	OBSSR , NIMHD , NIDA , NIMH , ORWH , NIDCD , SGMRO , ODP , NIA , NHLBI , NCI , NINR , NCCIH , NEI , NICHD	Apr 8, 2021	Jun 8, 2024	R01, R21, R03, R41/R42, R43/R44, R21/R33, UG3/UH3, R34
Notice of Special Interest: Research to Advance the Understanding and Management of the Multiple Organ Dysfunction Syndrome in Children (R01, R21)	NOT-HD-21-024	NICHD	Apr 1, 2021	May 8, 2023	R01, R21
Notice of Special Interest (NOSI): Identification of Biomarkers of HIV Pathogenesis and Substance Use Disorder Comorbidity	NOT-DA-21-014	NIDA	Mar 31, 2021	Sep 8, 2024	R01, R21, DP2, DP1, K99/R00, K01, R36, P01, R15, K24
Notice of Special Interest (NOSI): Stimulate Research on the Diagnosis, Treatment, and Mechanistic Understanding of Postural Orthostatic Tachycardia Syndrome (POTS)	NOT-HL-21-008	NHLBI , NINDS	Mar 26, 2021	May 8, 2024	R01
Notice of Special Interest (NOSI): Fundamental Science Research on Complementary and Integrative Health Approaches, Including Natural Products or Mind and Body Interventions	NOT-AT-21-006	NCCIH	Mar 19, 2021	Sep 8, 2024	R01, R21
Notice of Special Interest (NOSI) in Reducing Suicide Risk in Young People in Low- and Middle-Income Countries and Low-Resource Settings	NOT-MH-21-090	NIMH	Mar 2, 2021	May 8, 2024	R01, R33, R61/R33, R34, R21
Notice of Special Interest (NOSI): Neurological and Neurocognitive Sequelae from SARS-CoV-2 Infection and COVID-19 in Aging and Age-Related Neurodegeneration	NOT-AG-21-016	NIA	Feb 26, 2021	May 8, 2023	R01, R21, R03
Notice of Special Interest (NOSI): Telehealth Strategies for Individuals with HIV and Substance Use Disorders	NOT-DA-21-019	NIDA	Feb 10, 2021	Sep 8, 2024	R01, R03, R21
Notice of Special Interest (NOSI): Medical Consequences of Smoking and Vaping Drugs of Abuse in Individuals with HIV and COVID-19	NOT-DA-21-017	NIDA	Feb 4, 2021	Sep 8, 2024	R01, R03, R21
Notice of Special Interest (NOSI): Long-Term Neurocognitive Consequences of COVID-19 in Individuals Living with HIV and Substance Use Disorders	NOT-DA-21-018	NIDA	Feb 3, 2021	Sep 8, 2024	R01, R03, R21
Notice of Special Interest (NOSI): Understanding the effects of cancer and cancer treatment on aging trajectories and aging outcomes	NOT-CA-21-031	NCI , NIA	Jan 27, 2021	Jan 8, 2024	R21, R03, R01, U01, P01, K99/R00, K08, R43/R44, R41/R42, R13, R21/R33, K01, K23
Notice of Special Interest (NOSI): Effects of smoking and vaping on the risk and outcome of COVID-19 infection	NOT-DA-21-011	NIDA	Jan 26, 2021	Sep 8, 2024	R01, R03, R21
Notice of Special Interest (NOSI): Promoting Research on Interoception and Its Impact on Health and Disease	NOT-AT-21-002	NCCIH , NIDA , ORWH , NIMH , NIDCR , OBSSR , NIA , NIEHS , NCI	Jan 22, 2021	May 7, 2024	R01, R21
Notice of Special Interest: Alcohol-induced Tissue-specific and Organ System Diseases (R01/R21/R03)	NOT-AA-20-024	NIAAA	Jan 4, 2021	May 8, 2024	R01, R21, R03
Notice of Special Interest (NOSI): Adopting Techniques and Tools Developed from the BRAIN Initiative Toward NIMH Strategic Research Priorities	NOT-MH-21-115	NIMH	Dec 28, 2020	May 8, 2023	R01, R21, R15, P50
Notice of Special Interest (NOSI) for the NEI Anterior Segment Initiative (ASI): Identification and Development of New Biomarkers and Effective methods to Diagnose Dry Eye Disease.	NOT-EY-21-007	NEI	Dec 21, 2020	May 8, 2023	R01, R21, R43/R44, R41/R42
Notice of Special Interest: Advances in Research for the Treatment, Services, and Recovery of Alcohol Use Disorder	NOT-AA-20-022	NIAAA	Nov 27, 2020	Sep 8, 2023	R01, R03, R21
Notice of Special Interest (NOSI): Synthetic Biology for Biomedical Applications	NOT-EB-20-017	NIBIB , NCCIH , NIGMS , NICHD , NCI , NIA , NIAID	Nov 24, 2020	Jan 18, 2024	R01
NOSI: Academy of Finland (AKA) National Institutes of Health (NIH) Partnership Program	NOT-OD-21-021	NIH , NIAMS , NIDDK , NCI	Nov 13, 2020	Jan 8, 2024	R01
RESCINDED - Notice of Special Interest (NOSI): Effects of smoking and vaping on the risk and outcome of COVID-19 infection	NOT-DA-20-084	NIDA	Oct 27, 2020	Sep 8, 2024	R01, R03, R21
Notice of Special Interest (NOSI): The Influence of Host Resilience on Heterogeneity of Acute Respiratory Distress Syndrome/Acute Lung Injury (ARDS/ALI)	NOT-HL-20-814	NHLBI	Sep 15, 2020	Jul 6, 2024	R01
Notice of Special Interest (NOSI): Palliative Care in Heart, Lung, Blood, and Sleep Diseases	NOT-HL-20-737	NHLBI	Sep 9, 2020	Jul 6, 2023	R01
Notice of Special Interest (NOSI): Research in the Emergency Setting	NOT-NS-20-005	NINDS , NCI , NIDA , NHLBI , NIDCD , NIAAA , NICHD , NIA , NIGMS , NEI , NIMHD , NIMH	Sep 8, 2020	Sep 8, 2022	R01, R21, R03, K01, K99/R00, K08, K23, R13, R43/R44, R41/R42, P01, U01, R34, R35, RM1
Notice of Special Interest: Optimizing Precision Treatment of Gynecologic, Reproductive and Obstetrical Outcomes in Adolescents and Adults with PCOS and Associated Comorbid Conditions (Clinical Trial Optional)	NOT-HD-20-026	NICHD , ORWH	Sep 1, 2020	Sep 8, 2023	R01, R03
Notice of Special Interest: Alcohol and Aging	NOT-AA-20-019	NIAAA	Aug 19, 2020	Sep 8, 2023	R01, R03, R21
Notice of Special Interest (NOSI): Stimulating Intervention Research to Reduce Cardiopulmonary Impacts of Particulate Matter in Air Pollution among High-Risk Populations	NOT-HL-20-788	NHLBI , NIEHS	Jul 16, 2020	Sep 8, 2025	R01
Notice of Special Interest: Epidemiology and Prevention in Alcohol Research	NOT-AA-20-017	NIAAA	Jul 13, 2020	Sep 8, 2023	R01, R21, R03
Notice of Special Interest (NOSI): Utilizing Telemedicine or Other Remote-Based Platforms to Develop and Support Treatments for Substance Use Disorders	NOT-DA-20-058	NIDA	Jun 29, 2020	Jan 8, 2024	R01, R21
Notice of Special Interest (NOSI) in Research on Risk and Prevention of Black Youth Suicide	NOT-MH-20-055	NIMH , ODP , NIMHD	Jun 15, 2020	Jul 31, 2022	R01, R34
Notice of Special Interest (NOSI): Research on Co-morbid Substance Use, Substance Use Disorders, and Other Psychiatric Disorders	NOT-DA-20-004	NIDA , ORWH	Jun 4, 2020	May 8, 2023	R34, R21, R03, R01
Notice of Special Interest: Promoting Fundamental and Applied Research in Inflammation Resolution	NOT-ES-20-018	NIEHS , NHLBI , NIAMS	May 27, 2020	May 31, 2024	R21, R01
Notice of Special Interest (NOSI): Development and Preliminary Testing of Health-related Behavioral Interventions	NOT-OD-20-106	OBSSR , NIAMS , NIMH , NCCIH , NIDA , NIA , NCI , NIDCR , NINR	May 19, 2020	Sep 26, 2022	R01, R21, 333
Notice of Special Interest (NOSI): Advancing Research on SUD through Computational Neuroscience	NOT-DA-20-022	NIDA	May 5, 2020	Sep 8, 2023	R01, R21
Notice of Special Interest (NOSI): Cannabis, Prescription Opioid, or Prescription Benzodiazepine Drug Use Among Older Adults	NOT-DA-20-014	NIDA	Apr 22, 2020	Sep 8, 2023	R01, R03, R21
Notice of Special Interest (NOSI):Sleep and Substance Use Disorders	NOT-DA-20-021	NIDA	Mar 25, 2020	Sep 8, 2023	R01, R03, R21, K99/R00, R61/R33
Notice of Special Interest to Highlight High Priority Opportunities for Intervention Development Research in Geriatric Mental Health	NOT-MH-20-027	NIMH	Mar 19, 2020	Sep 8, 2023	R01, R21, R61/R33, R34
Notice of Special Interest: Alcohol and Cancer Control	NOT-CA-20-034	NCI	Mar 19, 2020	Sep 9, 2023	R01, R21, R03, 333
Notice of Special Interest (NOSI): Effects of Cannabis Use and Cannabinoids on the Developing Brain	NOT-DA-20-039	NIDA	Mar 5, 2020	Sep 8, 2023	R01, R03, R21
Notice of Special Interest (NOSI): Going Global: Using Gene Network Analyses to Understand the Etiology of SUD	NOT-DA-20-020	NIDA	Feb 26, 2020	Sep 8, 2023	R01, R03, R21, 333
Notice of Special Interest (NOSI): The HIV-HCV-Substance Use Disorder Syndemic: Therapeutic Approaches	NOT-DA-20-032	NIDA	Feb 21, 2020	Sep 8, 2023	R01
Notice of Special Interest (NOSI): Preclinical and Clinical Studies of the Interactions of Opioids and Stimulants	NOT-DA-20-007	NIDA	Jan 6, 2020	Jun 5, 2023	R03, R21, R01
Notice of Special Interest (NOSI): Biomarkers and Biotypes of Drug Addiction	NOT-DA-20-012	NIDA	Jan 6, 2020	May 7, 2023	R01
Notice of Special Interest (NOSI): Modeling Social Contagion of Substance Use Epidemics	NOT-DA-20-009	NIDA	Jan 2, 2020	Jan 8, 2023	R01, R03, R21
Notice of Special Interest (NOSI): Competitive Supplements/Revisions (R01) Available for INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndromE) Project (Competitive Supplement/Revision Clinical Trial Optional)	NOT-OD-20-023	NIH , NIMH , NCI , NIEHS , NIDCR , NHLBI , NICHD , NIDCD , NIAMS , NINDS , NIMHD , NIA	Dec 18, 2019	Sep 8, 2022	R01
Notice of Special Interest: Advancing Research for Tickborne Diseases (TBDs)	NOT-AI-20-005	NIAID , NCCIH , NIAMS , NIMH , NINDS	Nov 12, 2019	Jan 8, 2023	R01, R41/R42, R43/R44, R15
Notice of Special Interest (NOSI): Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R01, R21, R03)	NOT-DA-19-037	NIDA	Jul 11, 2019	Sep 8, 2022	R01, R21, R03

Expired NOSIs

Title	Notice Number	Organization	Release Date	Expiration Date	Activity Code(s)
Notice of Special Interest (NOSI): Advancing Research on Early Pregnancy Loss	NOT-HD-22-026	NICHD ORWH	Jul 5, 2022	n/a	R01, R21
Notice of NIDA Participation in NOT-MH-21-105, "Notice of Special Interest: Advancing Health Communication Research on HIV Prevention, Treatment and Cure"	NOT-DA-21-079	NIDA	Feb 16, 2022	n/a	R21, R01, R34, DP1, DP2, R03
Notice of NIAMS' Participation in NOT-MD-22-006, "Notice of Special Interest (NOSI): Research to Address Vaccine Hesitancy, Uptake, and Implementation among Populations that Experience Health Disparities"	NOT-AR-22-017	NIAMS	Feb 4, 2022	n/a	R01
Notice of NIDA's Participation in NOT-MD-22-006 "Notice of Special Interest (NOSI): Research to Address Vaccine Hesitancy, Uptake, and Implementation among Populations that Experience Health Disparities"	NOT-DA-22-002	NIDA	Jan 20, 2022	n/a	R01, 333, R21
Notice of Special Interest (NOSI) in Migraine and Headache Research	NOT-NS-22-051	NINDS	Dec 27, 2021	May 8, 2022	U01, K01, UG3/UH3, K22, K99/R00, K02, K08, R01, F30, K23, F32, R21, F31, R61/R33
Notice of Special Interest (NOSI) in NINDS mission relevant Pain Research	NOT-NS-22-050	NINDS	Dec 27, 2021	May 8, 2022	K01, UG3/UH3, K99/R00, K22, K08, R01, K02, F30, K23, R21, F32, F31, U01, U24, R61/R33
Notice of NHLBI Participation in NOT-AT-21-002 "Notice of Special Interest (NOSI): Promoting Research on Interoception and Its Impact on Health and Disease (R01)	NOT-HL-21-037	NHLBI	Oct 26, 2021	n/a	R01
Notice of Special Interest (NOSI): Electronic Nicotine Delivery Systems (ENDS) and Alternative Nicotine and Tobacco Delivery Systems: Population, Clinical and Applied Prevention Mechanisms of Health Effects	NOT-OD-21-137	ODP NIMHD NCI NIDA NIDCR	Jun 28, 2021	Dec 8, 2021	333, R34, R01, R21, R03
Notice of Special Interest (NOSI): Promoting Viral Suppression among Individuals from Health Disparity Populations Engaged in HIV Care	NOT-MD-21-015	NIMHD NIMH NIDA	Mar 3, 2021	May 8, 2021	R01
Notice of Special Interest (NOSI): Multi-Level HIV Prevention Interventions for Individuals at the Highest Risk of HIV Infection	NOT-MD-21-014	NIMHD NIMH NIDA	Mar 3, 2021	May 8, 2021	R01
Notice of Special Interest (NOSI): Aging-Relevant Behavioral and Social Research on Coronavirus Disease 2019 (COVID-19)	NOT-AG-21-015	NIA	Jan 26, 2021	Sep 10, 2021	R01, R03, R21, U19, P01, R21/R33
RESCINDED - Notice of Special Interest (NOSI): Research to Address Vaccine Hesitancy, Uptake, and Implementation among Populations that Experience Health Disparities	NOT-MD-21-008	NIMHD NCI NHLBI NIAAA NIAID NIAMS NIDCR NIMH NINR OBSSR ODP ORWH	Dec 17, 2020	Jan 8, 2022	R01
Notice of Special Interest (NOSI): Comprehensive Care for Adults with Type 2 Diabetes Mellitus from Health Disparity Populations	NOT-MD-20-026	NIMHD	Aug 11, 2020	May 8, 2021	R01
Notice of Special Interest: Basic and Translational Research on Affective, Motivational, and Social Function in Normative Aging and/or Alzheimers Disease and Related Dementias (AD/ADRD)	NOT-AG-20-040	NIA	Aug 3, 2020	Jan 8, 2022	R01, R21
Notice of Special Interest: Fundamental and Translational Research on Decision Making in Aging and/or Alzheimers Disease and Alzheimers Disease Related Dementias (AD/ADRD)	NOT-AG-20-039	NIA	Jul 21, 2020	Jan 8, 2022	R01, R21
RESCINDED - Notice of Special Interest (NOSI): Heart, lung, blood and sleep focused ancillary studies to large ongoing clinical trials	NOT-HL-20-755	NHLBI	Apr 29, 2020	May 8, 2022	R01
Notice of Special Interest: Health Services Research on Minority Health and Health Disparities (R01- Clinical Trial Optional)	NOT-MD-20-011	NIMHD NIAAA NIDA OBSSR NCI NIDCR	Mar 27, 2020	May 8, 2021	R01
Notice of Special Interest (NOSI): Advancing Head and Neck Cancer Early Detection Research (AHEAD)	NOT-CA-20-031	NCI NIDCR	Mar 10, 2020	Jan 8, 2022	R03, R21, R01
Notice of Special Interest to Highlight Research Priorities for Risk Algorithms Applications in Healthcare Settings to Improve Suicide Prevention	NOT-MH-20-031	NIMH	Feb 14, 2020	Jan 8, 2022	R34, R01, R21, R03
Notice of Special Interest (NOSI): Drug-drug interactions among substances of abuse, medications to treat HIV infection, and pharmacotherapies to treat substance use disorders	NOT-DA-20-013	NIDA	Feb 6, 2020	May 8, 2022	R01, R03, R21
Notice of Special Interest (NOSI): NIH Research Project Grants on Down Syndrome (R01) for the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project	NOT-OD-20-025	NIH NIAID NICHD NIAMS NHLBI NIEHS NIDCR NIMHD NIDCD NIA NINDS NIMH NEI	Dec 18, 2019	Jan 8, 2022	R01
Notice of Special Interest: Exploring the Mechanisms Underlying Analgesic Properties of Minor Cannabinoids and Terpenes	NOT-AT-20-002	NCCIH	Dec 13, 2019	Jan 8, 2022	R01, R21
Notice of Special Interest on Neurobehavioral Mechanisms of Social Isolation and Alcohol Use Disorder (AUD)	NOT-AA-19-031	NIAAA	Nov 12, 2019	Feb 8, 2022	R01
Notice of Special Interest: Nutrigenetics and Nutrigenomics Approaches for Nutrition Research	NOT-DK-19-019	NIDDK NCCIH	Sep 25, 2019	Jan 8, 2022	R01
Notice of Special Interest in High Priority Research Areas for Sex and Gender Influences on the Adolescent Brain and the Mental Health of Girls and Young Women (Ages 12-24)	NOT-MH-19-039	NIMH	Sep 9, 2019	May 18, 2022	R21, R01, P50
Notice of Special Interest (NOSI): Epidemiology of Drug Abuse	NOT-DA-19-066	NIDA	Aug 29, 2019	Jan 8, 2022	R01, R21, R03, 333
Notice of Special Interest (NOSI): Public Health Research on Cannabis	NOT-DA-19-065	NIDA	Aug 14, 2019	Jan 8, 2022	R01, R21, R03, 333
Notice of Special Interest (NOSI): The Application of Big Data Analytics to Drug Abuse Research	NOT-DA-19-041	NIDA	Jul 12, 2019	Jan 8, 2022	R01, R21, R03
Notice of Special Interest (NOSI): Gene-Environment Interplay in Substance Use Disorders (R01, R21)	NOT-DA-19-038	NIDA	Jul 10, 2019	Jan 8, 2022	R01, R21
Notice of Special Interest (NOSI): Understanding Factors in Infancy and Early Childhood (Birth to 24 months) That Influence Obesity Development	NOT-HL-19-695	NHLBI	May 21, 2019	May 25, 2020	R01
Notice of Special Interest to Highlight High Priority Research Opportunities on Suicide Prevention Crisis Services	NOT-MH-19-025	NIMH	Apr 23, 2019	Jan 8, 2022	R34, R01, R21, R03