The NIH is deeply concerned for the health and safety of people involved in NIH research, and about the effects on the biomedical enterprise in the areas affected by the HHS declared public health emergency for COVID-19. Due to the potential exceptional impact, we want to assure our recipient community that NIH will be doing our part to help you continue your research.
This is a rapidly evolving situation and we will provide updated guidance and information as it becomes available.
See page update history.
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Guidance
NOT-OD-23-095: Expiration of the COVID-19 Public Health Emergency
Overview of Grant Flexibilities
- Reminder of COVID-19-Related Flexibilities for NIH Grants: Open Mike blog
Proposal Submission & Award Management
- Contracts
- Contracts must be handled on a case-by-case basis. Details regarding any contract must be directed to the cognizant Contracting Officer. Salary changes must be handled by the contracting officer.
- Contracts must be handled on a case-by-case basis. Details regarding any contract must be directed to the cognizant Contracting Officer. Salary changes must be handled by the contracting officer.
- Application Preparation
NOT-OD-23-067: Clarification and Guidance for Applicants Preparing Applications for the Spring 2023 Due Dates During the COVID-19 Pandemic
- NOT-OD-20-086: Flexibilities Available to Applicants and Recipients of Federal Financial Assistance Affected by COVID-19
- Late Applications
- Post-Submission Materials
NOT-OD-23-066: Extending the Special Exception to the NIH/AHRQ/NIOSH Post-Submission Material Policy During the COVID-19 Pandemic: August/October 2023 Councils
- NOT-OD-23-006: Extending the Special Exception to the NIH/AHRQ/NIOSH Post-Submission Material Policy During the COVID-19 Pandemic: May 2023 Councils
- Extensions for Early Career Scientists
- NIH Open Mike: Clarifying NIH’s Approach to Granting ESI Extensions
- NOT-OD-21-052: Reminder – Requesting Extensions for Early Career Scientists Whose Career Trajectories Have Been Significantly Impacted by COVID-19
- Temporary Extension of Eligibility
- NOT-OD-22-062 - Further Continuation of Temporary Extension of Eligibility for the NIH K99/R00 Pathway to Independence Award During the COVID-19 Pandemic
- NOT-DE-21-021 - Notice to Extend Eligibility for Submission of Pathway to Independence Award Applications (K99/R00) to NIDCR due to Covid-19 disruptions
- NOT-GM-22-020 - Notice to Extend Eligibility for Submission of "Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00)" Applications Due to COVID–related Disruptions
- NOT-OD-22-007 - Flexibility Available to Lasker Clinical Research Scholars Affected by COVID-19
- NOT-AI-21-061 - Notice to Extend Eligibility for Submission of K99/R00 Pathway to Independence Award Applications (and Physician-Scientist K99/R00) due to COVID–related Disruptions
- NOT-AI-21-062 - Notice to Extend Eligibility for Submission to PAR-19-371, NIAID Career Transition Award (K22 Independent Clinical Trial Not Allowed) due to COVID-related Disruptions
- NOT-DE-21-003: Continuation of Temporary Extension of Eligibility for the NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00) During the COVID-19 Pandemic
- NOT-OD-21-106: Continuation of Temporary Extension of Eligibility for the NIH K99/R00 Pathway to Independence Award During the COVID-19 Pandemic
- NOT-DK-21-054: Temporary Extension of Eligibility for the NIDDK K01 Mentored Research Scientist Development Award During the COVID-19 Pandemic
- NOT-GM-20-026: Guidance for Cost-Related Flexibilities Available to Support of Competitive Research (SCORE) Award Recipients Affected by COVID-19 - NOT-GM-20-026
- NIH Implementation of OMB Memorandum M-20-26 "Extension of Administrative Relief for Recipients and Applicants of Federal Financial Assistance Directly Impacted by the Novel Coronavirus (COVID-19) due to Loss of Operations" - 6/25/2020
- Update: Effective October 1, 2020, the flexibility for recipients to continue charging salaries and benefits to active NIH awards consistent with the recipients' policy of paying salaries (under unexpected or extraordinary circumstances), has ended. Any requests after that date will be considered by the funding IC on a case by case basis. As a reminder, recipients must maintain appropriate records and cost documentation in order to substantiate the charging of any salaries and other project activities costs related to interruption of operations or services.
- Update: Effective October 1, 2020, the flexibility for recipients to continue charging salaries and benefits to active NIH awards consistent with the recipients' policy of paying salaries (under unexpected or extraordinary circumstances), has ended. Any requests after that date will be considered by the funding IC on a case by case basis. As a reminder, recipients must maintain appropriate records and cost documentation in order to substantiate the charging of any salaries and other project activities costs related to interruption of operations or services.
- M-20-26
issued June 18, 2020: Extension of Administrative Relief for Recipients and Applicants of Federal Financial Assistance Directly Impacted by the Novel Coronavirus (COVID-19) due to Loss of Operations
- M-20-11
issued March 9, 2020: Administrative Relief for Recipients and Applicants of Federal Financial Assistance Directly Impacted by the Novel Coronavirus (COVID-19)
Human Subjects & Clinical Trials
NOT-OD-23-097: NIH Can No Longer Grant Common Rule Exceptions to the Use of a Single IRB for Multi-site Research After the COVID-19 Public Health Emergency Expiration Date of May 11, 2023
- NOT-OD-20-087: Guidance for NIH-funded Clinical Trials and Human Subjects Studies Affected by COVID-19
- FDA Guidance on Conduct of Clinical Trials of Medical Products during COVID-19 Pandemic
- OHRP COVID-19 Resources
- Considerations for New and Ongoing Human Subjects Research During the COVID-19 Public Health Emergency (Word) - 3/14/2022
- NOT-OD-21-006 - Exceptions to Use of a Single IRB During the Coronavirus Disease 2019 (COVID-19) Public Health Emergency - 10/23/2020
Animal Welfare
NOT-OD-22-207: OLAW Waivers to Conduct Semiannual Facility Inspections due to COVID-19 Will Expire October 1, 2022
- COVID-19 Pandemic Contingency Planning for Animal Care and Use Programs
- NOT-OD-21-080: Updated Notice of Limited Availability of Research Non-Human Primates
Peer Review
- Review Process
- Coronavirus Update: Additional Guidance for NIH Peer Reviewers (August/October 2021 Council) – January 5, 2021 (Expired)
- Coronavirus Update: Additional Guidance for NIH Peer Reviewers (Summer 2020 Meetings/August-October 2020 Council) – June 9, 2020 (Expired)
- Coronavirus Update: Guidance for Peer Reviewers
- Based on NIH Guidance on Travel and Meetings
, in-person NIH peer review meetings are being held in alternate formats. Scientific review officers will be in contact with peer reviewers about these changes.
- Coronavirus Update for May 2022 Council Round
FAQs
Funding Opportunities
- Funding Opportunities published in the NIH Guide for Grants & Contracts
- "Open Mike" Blog: COVID-19 Funding and Funding Opportunities
Funded Grants
Use the following links to explore NIH COVID-19-related grant funding.
All COVID-19 research grant funding
All COVID-19 research grant funding

- Grants funded under special COVID-19 appropriations
- Grants funded under regular NIH appropriations
Grant data are updated each weekend. Use the RePORTER search screen to filter these results by other criteria, including individual special appropriations.
A Federal-wide listing of acquisitions related to the COVID-19 response is available from the Federal Procurement Data System in a special COVID-19 report.
Resources
- New NIH Resource to Analyze COVID-19 Literature: The COVID-19 Portfolio Tool
- Supporting Yourself and Your Trainees During the Coronavirus Pandemic Online Workshops
- NIH Office of Intramural Training & Education: Virtual NIH Activities for Trainees Outside the NIH
- CDC Website: Coronavirus Disease 2019 (COVID-19)
including its guidance for Institutes of Higher Education
and for mental health and coping
- WHO Website: Coronavirus disease (COVID-19) outbreak
- General Information on NIH Extramural Response to Natural Disasters and Other Emergencies
- Infographic - 2020 NIH Extramural Surveys: The Impact of COVID-19 on the Research Community