PA-20-188 - NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed) is used for the submission of applications to the following Notices of Special Interest (NOSIs)

Active NOSIs

Title Notice Number Organization Release
Date
Expiration
Date
Activity
Code(s)
Notice of Special Interest (NOSI): School Mental Health: Innovative Approaches to Expand Access to Evidence-Based Interventions and Services NOT-MH-24-165 NIMH Mar 25, 2024 Mar 17, 2026 R34, R01, K08, K99/R00, K23, K01
Notice of Special Interest (NOSI): Epidemiologic Studies to Assess the Impact of Incretin Mimetics on New and Recurrent Cancer Risk NOT-CA-24-037 NCI Mar 7, 2024 May 9, 2026 K08, K22, R01, K99/R00, R21, P01
Notice of Special Interest (NOSI): Training and Career Development in Dissemination and Implementation Science for Research in Communication Disorders NOT-DC-24-024 NIDCD Mar 6, 2024 May 8, 2024 K01, R25, K18, F31, K08, K99/R00, K23, K25, T35, T32, F30, FM1, F32, K24
Notice of Special Interest (NOSI): Encouraging Health Disparities and Health Equity Workforce Development within NIDDK Mission Areas NOT-DK-24-015 NIDDK Mar 1, 2024 Apr 7, 2027 F30, R13, R25, U2C, F32, K23, K99/R00, K25, K08, K01, T32, F99/K00, F31, T35
Notice of Special Interest (NOSI): Myelin plasticity in sculping addiction neurocircuitry NOT-DA-25-028 NIDA Feb 26, 2024 Jan 8, 2027 F30, R03, F31, R01, K99/R00, R21, K01, F32
Notice of Special Interest (NOSI): Addressing Health Disparities and Advancing Health Equity in NIDDK Diseases NOT-DK-24-007 NIDDK Dec 20, 2023 Jan 8, 2027 K23, R01, K08, RC2, K99/R00, K01, R03, K25, R43/R44, U01, R21, R41/R42, DP1, U34
Notice of Special Interest (NOSI): Quantum Sensing Technologies in Biomedical Applications NOT-EB-23-022 NIBIB , NCATS , NCI , NEI , NHLBI , NIGMS Dec 13, 2023 Jan 27, 2027 R35, RM1, R21, R01, U01, R15, R13, K99/R00
Notice of Special Interest (NOSI): Development and Application of Novel Chemical Approaches to Discover Therapeutic Targets for Substance Use Disorders NOT-DA-25-027 NIDA Nov 28, 2023 May 8, 2027 K01, R21, F31, F30, R03, F32, R01, K99/R00
Notice of Special Interest (NOSI): Applications of Data Science in Translational Dental, Oral, and Craniofacial Research NOT-DE-24-003 NIDCR Oct 23, 2023 May 8, 2026 UE5, R41/R42, U01, K02, K25, F30, R13, D43, F99/K00, F33, F31, K99/R00, R16, D71, R15, R43/R44, K18, K43, K08, R01, R21, K23, K01, F32, R03, G11, K22
Notice of Special Interest (NOSI):?Advancing Data Science Research in HIV: Responding to a Dynamic, Complex, and Evolving HIV Epidemic with Artificial Intelligence/Machine Learning NOT-MH-23-350 NIMH Sep 18, 2023 Jan 8, 2027 R25, R15, R21, K08, K99/R00, K43, F31, F30, K01, T32, R03, R34, K23, R01, F32, K24
Notice of Special Interest (NOSI): Mechanisms Driving Obesity and Prostate Cancer Risk NOT-CA-23-089 NCI Aug 30, 2023 Sep 8, 2024 R01, K99/R00, R21, K08, K22
Notice of Special Interest in Research on Family Support and Rejection in the Health and Well-Being of SGM Populations NOT-OD-23-166 OD , NCI , NIA , NIAMS , NICHD , NIDDK , NIMH , NIMHD , OBSSR , ODP , ORWH , THRO Aug 28, 2023 May 8, 2026 R21, R15, R01, R34, K25, K99/R00, K01, R03, P01, K08, K23
Notice of Special Interest (NOSI): Neuropathogenesis of CNS Complications Associated with HIV NOT-MH-23-280 NIMH , NINDS Jun 15, 2023 Sep 8, 2026 K24, K08, R01, K01, K23, R15, K99/R00, F30, F32, K43, F31, T32, R03, R21, R25
Notice of Special Interest (NOSI): Eradication of HIV-1 from Central Nervous System Reservoirs NOT-MH-23-260 NIMH , NINDS Jun 15, 2023 Sep 8, 2026 R21, K43, K01, R25, K08, K99/R00, R01, F30, F32, T32, R03, R15, F31, K23, K24
Notice of Special Interest (NOSI): Clinical Studies of CNS Complications in People with HIV NOT-MH-23-255 NIMH , NINDS Jun 15, 2023 Sep 8, 2026 K43, K01, R25, K99/R00, R21, K08, F30, T32, R01, F32, F31, R03, R15, K23, K24
Notice of Special Interest (NOSI): Applications of Data Science in Translational Dental, Oral, and Craniofacial Research NOT-DE-23-002 NIDCR Jun 12, 2023 May 8, 2026 K43, K18, R01, K08, K99/R00, K01, K23, R21, F99/K00, F32, F31, R16, G11, K22, R15, R03, UE5, U01, R13, K25, K02, F30, F33, D43, D71
Notice of Special Interest (NOSI): Implementation Science to Advance the United States HIV Prevention and Treatment Goals and the Global HIV Prevention and Treatment Targets NOT-MH-23-275 NIMH Jun 5, 2023 Sep 8, 2026 R15, R25, R21, K99/R00, K08, R34, F30, T32, K01, K43, F31, R03, K23, K24, R01, F32
Notice of Special Interest (NOSI): Mental Health Comorbidities in HIV Prevention and Treatment NOT-MH-23-265 NIMH Jun 1, 2023 Sep 8, 2026 R15, K43, R21, K08, R34, K99/R00, F30, T32, K01, R03, F31, K24, F32, R01, K23
Notice of Special Interest (NOSI): Intersectional Stigma and Discrimination (ISD), or Other Social and Structural Determinants of Health (SSDOH) in HIV Prevention and Treatment NOT-MH-23-270 NIMH May 22, 2023 Sep 8, 2026 R15, R21, R25, R34, K08, K99/R00, T32, K01, F30, D43, R03, F31, K43, K24, K23, R01, F32
Notice of Special Interest (NOSI): Developmentally Tailored HIV Prevention and Care Research for Adolescents and Young Adults NOT-MH-23-250 NIMH May 19, 2023 Sep 8, 2026 K43, R41/R42, R21, K08, R25, K99/R00, T32, K01, F30, R34, R03, F31, R15, R43/R44, K24, K23, F32, R01
Notice of Special Interest: Advancing mHealth Interventions for Understanding and Preventing Alcohol-Related Domestic Violence NOT-AA-23-003 NIAAA Mar 6, 2023 Sep 8, 2026 R01, R21, R34, K99/R00
Notice of Special Interest (NOSI): Research on the Etiology, Early Detection, Screening and Prevention of Early-Onset Colorectal Cancer NOT-CA-23-018 NCI Jan 19, 2023 Sep 8, 2024 K01, R01, K22, K08, R21, U34, K99/R00, P01, R34
Notice of Special Interest (NOSI): Career Development Opportunities for Research Within the Mission of the Division of Cancer Prevention at the National Cancer Institute NOT-CA-23-035 NCI Jan 18, 2023 Nov 13, 2024 K22, K08, K99/R00, K01
Notice of Special Interest (NOSI): Adaptive Biomaterials for Cancer Biology NOT-CA-23-030 NCI Jan 10, 2023 May 7, 2025 R01, K22, K99/R00
Notice of Special Interest (NOSI): Optimization of Data Storage and Utilization for the Sequence Read Archive (SRA) NOT-GM-23-015 NIGMS , NLM , ODSS Dec 14, 2022 Dec 19, 2025 R41/R42, R43/R44, R01, K08, RM1, R21, K25, K99/R00, K23, F30, F32, F33, F31, R16, R35, R15
Notice of Special Interest (NOSI): Chemoproteomic Approaches for Discovery of Targets and Therapeutics to Treat Substance Use Disorders NOT-DA-24-005 NIDA Nov 7, 2022 Jan 8, 2026 R03, F32, R21, F31, R01, K99/R00, F30, K01
Notice of Special Interest (NOSI) Targeting Epigenetic Regulators for Treating Addiction and Substance Use Disorders NOT-DA-24-004 NIDA Nov 3, 2022 Jan 8, 2026 R03, R01, K99/R00, R21, F31, F30, F32, K01
Notice of Special Interest (NOSI): Single-Cell Level Spatiotemporal Mapping of Dental and Craniofacial Embryogenesis NOT-DE-22-003 NIDCR Jul 18, 2022 Sep 8, 2025 R15, R01, K18, K99/R00, K02, R21, K01, R03, R16, K22
Notice of Special Interest (NOSI): Research on the Health of Sexual and Gender Minority (SGM) Populations NOT-MD-22-012 NIMHD , NCCIH , NCI , NHGRI , NIA , NIAID , NIAMS , NICHD , NIDA , NIDCD , NIDCR , NIDDK , NIEHS , NINDS , NINR , ODP , ORWH , SGMRO Jul 11, 2022 Aug 8, 2025 R01, K08, K99/R00, K01, K23, R21, K25, K18, R03, P50, F99/K00, UG3/UH3, R34, R25, U01
Notices of Special Interest (NOSI): High Priority Areas in Integrative Neuroscience Branch in the Division of Neuroscience and Behavior NOT-DA-22-058 NIDA Jun 2, 2022 Jan 8, 2026 R21, R03, R36, K01, K99/R00, R01
Notice of Special Interest (NOSI): Climate Change and Health NOT-ES-22-006 NIEHS , FIC , NCI , NHGRI , NHLBI , NIA , NIAID , NIAMS , NICHD , NIDCR , NIMH , NIMHD , NINDS , NINR , NLM , ODP Jun 1, 2022 May 8, 2025 R21, F31, D43, K01, R03, K43, K99/R00, U01, U19, R01, F32, K23, F30, R21/R33
Notice of Special Interest (NOSI): Mentored Career Development Awards to Foster the Careers of Investigators Pursuing Research Related to Down syndrome as Part of the INCLUDE Project NOT-OD-22-124 OD , FIC , NCI , NEI , NHLBI , NIA , NIAMS , NICHD , NIDCD , NIDCR , NIMHD , NINDS May 24, 2022 Nov 13, 2024 K99/R00, K23, K08, K01, K43, UE5
Notice of Special Interest (NOSI): Basic Mechanisms of Cannabis and Cannabinoid Action in Cancer NOT-CA-22-085 NCI May 5, 2022 Jul 5, 2027 K22, R01, K08, K01, R21, R03, K99/R00
Understanding the Basic Mechanisms of Immune-related Adverse Events (irAEs) in Cancer Immunotherapy NOT-CA-22-063 NCI , NIAID , NIAMS , NIDCR May 3, 2022 Jul 5, 2024 R01, R21, K99/R00, K01, K08, K22, R03, R15
Notice of Special Interest (NOSI): Technological Innovations for Advancing Clinical SPECT Imaging NOT-EB-22-006 NIBIB Mar 21, 2022 May 8, 2024 R21, F30, K01, R13, K23, K25, R43/R44, K08, R01, K99/R00, R41/R42, F32, R03, F31
Notice of Special Interest (NOSI): Research on Drowning Prevention NOT-HD-21-048 NICHD , NIMHD , ODP Feb 15, 2022 May 8, 2024 R01, K23, K08, K99/R00, R21, R03
Notice of Special Interest (NOSI): Research Addressing Eye and Vision Health Equity/Health Disparities NOT-EY-22-004 NEI , NIMHD Feb 14, 2022 Jan 25, 2025 R01, UG1, F31, R21, 333, K99/R00, K08, F30, K23, R43/R44, R34, R41/R42, F32
Notice of Special Interest: NIMH Priorities on Research on Aggression and Violence Against Others NOT-MH-22-095 NIMH Feb 3, 2022 Jan 8, 2025 R36, R01, R34, R21, F32, R21/R33, R03, R61/R33, U01, K08, R15, K23, P50, F30, K99/R00, F31, K22, K01
Notice of Special Interest (NOSI): Inclusion of Economic Factors and Outcomes in Infectious Disease Modeling Studies NOT-GM-22-021 NIGMS Feb 1, 2022 Jan 8, 2025 RM1, R35, R01, K99/R00, K25, K08, F30, K23, F33, R15, F32, F31
Notice of Special Interest: Research on Pain, Pain Management, and Opioids in Aging NOT-AG-22-004 NIA Dec 22, 2021 Jan 8, 2025 F31, P01, K99/R00, K08, R01, K01, R43/R44, F32, 332, F33, F99/K00, R15, K24, R21, K02, K25, R25, F30, K23, R36, R41/R42, SB1, K76, K22, K07, R13, R21/R33, U19
Notice of Special Interest (NOSI): Research in the Chemistry and Pharmacology of Addictive Drugs NOT-DA-23-002 NIDA Nov 30, 2021 Jan 8, 2025 R03, R21, R01, K99/R00, R36, K01
Notice of Special Interest (NOSI): Dietary Effects on Nutrient Sensing Pathways in Tumor Etiology and Prevention NOT-CA-21-121 NCI Oct 4, 2021 Sep 8, 2024 K22, K08, R15, R01, R21, K99/R00,
Notice of Special Interest (NOSI): Advancing HIV/AIDS Research through Computational Neuroscience NOT-DA-21-030 NIDA Jun 22, 2021 Jan 8, 2025 R01, R21, R03, DP2, DP1, K99/R00, K01, R36, P01, R15, K24
Notice of Special Interest: NIDCD Health Disparities and Inequities Research NOT-DC-21-003 NIDCD , SGMRO Jun 11, 2021 May 8, 2024 R01, R21, P50, F30, F31, F32, F99/K00, K01, K08, K18, K23, K24, K25, K99/R00, 333, R41/R42, R43/R44
Notice of Special Interest (NOSI): Identification of Biomarkers of HIV Pathogenesis and Substance Use Disorder Comorbidity NOT-DA-21-014 NIDA Mar 31, 2021 Sep 8, 2024 R01, R21, DP2, DP1, K99/R00, K01, R36, P01, R15, K24
Notice of Special Interest: Advancing Health Communication Research on HIV Prevention, Treatment and Cure NOT-MH-21-105 NIMH Mar 2, 2021 May 9, 2024 R01, R21, R34, K01, K08, K23, R03, K99/R00, K24, R15, D43, F30, F31, F32, T32
Notice of Special Interest (NOSI): High-Priority Interest to Enhance Data Science Research Training in Addiction Research NOT-DA-21-013 NIDA , NIAAA Jan 27, 2021 Dec 9, 2024 F30, F31, F32, T32, F99/K00, K99/R00, K01, K08, K23, K25, R25, R15, 333,

Expired NOSIs

Title Notice Number Organization Release
Date
Expiration
Date
Activity
Code(s)
Notice of Special Interest (NOSI): Research on the Health of Bisexual and Bisexual+ People NOT-OD-22-166 OD NCCIH NIA NIAAA NIAID NICHD NIDA NIDCR NIMH NIMHD NINDS ODP Aug 11, 2022 Sep 8, 2023 K24, U01, R01, K01, R15, R03, K76, R34, K99/R00, T32, F32, UG3/UH3, R21, K23, F31
Notice of Special Interest: Research on Alcohol and Coronavirus Disease (COVID-19) within the Mission of NIAAA NOT-AA-22-012 NIAAA Apr 29, 2022 Mar 6, 2024 R01, R03, R21, K99/R00
Notice of Special Interest (NOSI) in Migraine and Headache Research NOT-NS-22-051 NINDS Dec 27, 2021 May 8, 2022 U01, K01, UG3/UH3, K22, K99/R00, K02, K08, R01, F30, K23, F32, R21, F31, R61/R33
Notice of Special Interest (NOSI) in NINDS mission relevant Pain Research NOT-NS-22-050 NINDS Dec 27, 2021 May 8, 2022 K01, UG3/UH3, K99/R00, K22, K08, R01, K02, F30, K23, R21, F32, F31, U01, U24, R61/R33
Notice of Special Interest (NOSI): Promoting Pain Research Within the NIAMS Mission Areas NOT-AR-22-007 NIAMS Sep 23, 2021 Jan 10, 2023 R01, R21, R15, R33, R13, R34, K99/R00, K24, K01, K25, K23, K08, 332
Notice of Special Interest (NOSI): NINR Priority Areas for Training and Career Development Awards NOT-NR-21-001 NINR Mar 10, 2021 Sep 8, 2023 F31, F32, K01, K23, K24, K99/R00, T32
Notice of Special Interest (NOSI): Understanding the effects of cancer and cancer treatment on aging trajectories and aging outcomes NOT-CA-21-031 NCI NIA Jan 27, 2021 Jan 8, 2024 R21, R03, R01, U01, P01, K99/R00, K08, R43/R44, R41/R42, R13, R21/R33, K01, K23
Notice of Special Interest (NOSI): Research in the Emergency Setting NOT-NS-20-005 NINDS NCI NIDA NHLBI NIDCD NIAAA NICHD NIA NIGMS NEI NIMHD NIMH Sep 8, 2020 Sep 8, 2022 R01, R21, R03, K01, K99/R00, K08, K23, R13, R43/R44, R41/R42, P01, U01, R34, R35, RM1
Notice of Special Interest (NOSI) of NIDCR in Supporting Dental, Oral, and Craniofacial Research Using Bioinformatic, Computational, and Data Science Approaches NOT-DE-20-006 NIDCR Jun 5, 2020 Aug 8, 2023 R01, R21, R03, R41/R42, F99/K00, F30, F31, F32, F33, K01, K08, K23, K25, K22, K99/R00, K43, K18, R15, R43/R44


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