PA-24-247 - PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) is used for the submission of applications to the following Notices of Special Interest (NOSIs)

On This Page: 52

Active NOSIs

Title Notice Number Organization Release
Date		 Expiration
Date		 Activity
Code(s)
Notice of Special Interest (NOSI): Quantum Sensing in Biomedical Applications (SBIR/STTR) NOT-EY-24-014 NEI , NCATS , NCI , NHLBI , NIBIB Sep 20, 2024 Jan 27, 2027 R43/R44, R41/R42
Notice of Special Interest: Small Business Solutions to Enable Regional Genomic Medicine eConsult Services NOT-HG-24-041 NHGRI Sep 4, 2024 Sep 6, 2027 R41/R42, R43/R44
Notice of Special Interest: Small Business Solutions to Assist Genomics-Enabled Learning Health Systems (gLHS) NOT-HG-24-040 NHGRI Sep 4, 2024 Sep 6, 2027 R43/R44, R41/R42
Notice of Special Interest (NOSI): Advancing Precision Imaging for Enhanced Diagnosis and Treatment of Oral Lesions NOT-DE-25-034 NIDCR Aug 30, 2024 Sep 8, 2027 UG3/UH3, R43/R44, R01, R41/R42, R21
Notice of Special Interest (NOSI): Advancing Genomic Technology Development for Research and Clinical Application NOT-HG-24-036 NHGRI Jul 25, 2024 Jan 10, 2027 R01, R41/R42, R21, R43/R44
Notice of Special Interest (NOSI): Epigenetic Modulation of HBV cccDNA and integrated HBV DNA (iDNA): Implications for Epigenetic Treatment Strategies Against HBV in HIV/HBV Co-Infection NOT-AI-24-050 NIAID Jun 28, 2024 May 8, 2027 R41/R42, R43/R44, R01, R21
Notice of Special Interest (NOSI): Improving Adherence to Treatment and Prevention Regimens and Maintenance of Health Behaviors to Promote Health NOT-OD-24-146 OBSSR , NCCIH , NCI , NEI , NHLBI , NIA , NIDA , NIMH , NIMHD , NINR , OAR , ODP , ORWH , SGMRO Jun 24, 2024 Jul 14, 2027 P01, P30, R01, R03, UG3/UH3, R34, U24, R41/R42, R21, R43/R44, R21/R33, R61
Notice of Special Interest (NOSI): Translating Biomaterials-Based Technologies to Commercially Viable Products NOT-EB-24-001 NIBIB , NCATS , NCCIH , NHLBI , NIDCR Mar 29, 2024 Apr 6, 2027 R41/R42, R43/R44
Notice of Special Interest (NOSI): Research to Stimulate Development of Diagnostics, Therapeutics, and Vaccines for Herpes Simplex Virus (HSV) NOT-AI-24-028 NIAID Mar 27, 2024 Apr 6, 2027 R21, R41/R42, R43/R44, R03, R01
Notice of Special Interest: Womens Health Research NOT-OD-24-079 ORWH , FIC , NCATS , NCCIH , NCI , NEI , NHGRI , NHLBI , NIA , NIAAA , NIAID , NIAMS , NIBIB , NICHD , NIDA , NIDCD , NIDCR , NIDDK , NIEHS , NIGMS , NIMH , NIMHD , NINDS , NINR , NLM , OAR , OBSSR , ODP , ODS , ODSS , SGMRO Mar 26, 2024 Nov 5, 2027 R15, R01, K01, R16, K08, R21, K43, F31, R43/R44, R41/R42, F30, R03, K23, F32, R34
Notice of Special Interest (NOSI): Development of Imaging Techniques for High Resolution and Functional Scanning of In Vivo Human Sensory and Communication Systems NOT-DC-24-025 NIDCD Mar 22, 2024 May 8, 2027 R01, U01, R43/R44, R41/R42, R21
Notice of Special Interest (NOSI): Validation of Digital Health and Artificial Intelligence/Machine Learning Tools for Improved Assessment in Biomedical and Behavioral Research NOT-CA-24-031 NCI , NHLBI , NIA , NIDA , NIMH , NINR , OBSSR , ODSS Feb 15, 2024 Jul 6, 2025 R61/R33, R01, R21, R43/R44, R34, R41/R42
Notice of Special Interest (NOSI): Innovative Technologies for Research on Climate Change and Human Health NOT-ES-24-002 NIEHS , NCATS , NCCIH , NEI , NHLBI , NIA , NIAID , NIAMS , NLM Feb 15, 2024 Apr 6, 2025 R43/R44, R41/R42
Notice of Special Interest (NOSI): Advancing Genomic Medicine Research through Small Businesses NOT-HG-24-016 NHGRI Feb 14, 2024 Sep 7, 2026 R43/R44, R41/R42
Notice of Special Interest (NOSI): RNA Delivery Technologies to Allow Specific Tissue Target Homing (RNA-DASH) NOT-AI-24-007 NIAID , NCATS , NCI Feb 2, 2024 Jan 6, 2027 R43/R44, R41/R42
Notice of Special Interest (NOSI): Translation of BRAIN Initiative Technologies to the Marketplace NOT-MH-24-115 NIMH , NCCIH , NEI , NIA , NIAAA , NIBIB , NICHD , NIDA , NIDCD , NINDS Jan 8, 2024 Apr 6, 2027 R43/R44, R41/R42
Notice of Special Interest (NOSI): Addressing Health Disparities and Advancing Health Equity in NIDDK Diseases NOT-DK-24-007 NIDDK Dec 20, 2023 Jan 8, 2027 K23, R01, K08, RC2, K99/R00, K01, R03, K25, R43/R44, U01, R21, R41/R42, DP1, U34
Notice of Special Interest (NOSI): NIDCD is Interested in Supporting Research on the Impact of Post-Acute Sequelae of SARS-CoV-2 Infection on Mission Specific Sensory and Communication Disorders NOT-DC-24-001 NIDCD Dec 14, 2023 Jan 30, 2027 R41/R42, R43/R44, R01, R21
Notice of Special Interest (NOSI): SBIR/STTR High-Priority Areas for Digital Mental Health Innovations NOT-MH-24-120 NIMH Nov 29, 2023 Jan 6, 2027 R41/R42, R43/R44
Notice of Special Interest (NOSI): SBIR/STTR Program Priorities to Bridge Gaps in Advancing the NIMH Mission NOT-MH-24-110 NIMH Nov 29, 2023 Jan 6, 2027 R43/R44, R41/R42
Notice of Special Interest (NOSI): Using Targeted Degradation of Protein and non-Protein Targets for the Development of Novel Anti-Infectives NOT-AI-23-076 NIAID Oct 31, 2023 Jul 17, 2026 R03, R01, R21, R41/R42, R43/R44
Notice of Special Interest (NOSI): Applications of Data Science in Translational Dental, Oral, and Craniofacial Research NOT-DE-24-003 NIDCR Oct 23, 2023 May 8, 2026 UE5, R41/R42, U01, K02, K25, F30, R13, D43, F99/K00, F33, F31, K99/R00, R16, D71, R15, R43/R44, K18, K43, K08, R01, R21, K23, K01, F32, R03, G11, K22
Notice of Special Interest (NOSI): Advancing Genomic Medicine Research through Small Businesses NOT-HG-24-002 NHGRI Oct 11, 2023 Sep 7, 2026 R43/R44, R41/R42
Notice of Special Interest (NOSI): The Road to Prevention of Stillbirth NOT-HD-23-021 NICHD Oct 3, 2023 Nov 17, 2026 F31, R03, R15, K08, R01, R21, F30, U24, R43/R44, K23, R41/R42, R25, S06, F32, U01
Notice of Special Interest (NOSI): Small Business Initiatives for Innovative tools and Technologies for Improving Outcomes for Maternal Health NOT-EB-23-005 NIBIB , NCATS , NHLBI , NIAMS , NIMH , NIMHD , NINDS , ORWH Jul 26, 2023 Sep 6, 2026 U44, R43/R44, R41/R42
Notice of Special Interest (NOSI): Innovative Technologies to develop novel tools to prevent and treat HIV in underserved populations NOT-MH-23-200 NIMH , SGMRO Jul 18, 2023 Jan 6, 2027 R41/R42, R43/R44
Notice of Special Interest (NOSI): Advancing Biomedical Research in Pulmonary Non-Tuberculous Mycobacterial (NTM) Infections NOT-AI-23-050 NIAID Jun 27, 2023 Jul 17, 2026 R21, R41/R42, R43/R44, R01, U44
Notice of Special Interest (NOSI): Using Targeted Degradation of Protein and non-Protein Targets for the Development of Novel Anti-Infectives NOT-AI-23-049 NIAID Jun 23, 2023 Jul 17, 2026 R03, R01, R41/R42, R43/R44, R21
Notice of Special Interest (NOSI): Promoting Research and Development of Vaccines Against Enteric Viruses NOT-AI-23-048 NIAID Jun 15, 2023 Jul 17, 2026 R01, R43/R44, U44, R41/R42, R21
Notice of Special Interest (NOSI): Developmentally Tailored HIV Prevention and Care Research for Adolescents and Young Adults NOT-MH-23-250 NIMH May 19, 2023 Sep 8, 2026 K43, R41/R42, R21, K08, R25, K99/R00, T32, K01, F30, R34, R03, F31, R15, R43/R44, K24, K23, F32, R01
Notice of Special Interest (NOSI): Synthetic Biology for Biomedical Applications. NOT-EB-23-002 NIBIB , NCCIH , NCI , NHLBI , NIA , NIAID , NICHD , NIGMS Apr 14, 2023 May 17, 2026 R01, R21, R35, R41/R42, R43/R44
Notice of Special Interest (NOSI): Development of Innovative Informatics and Data Science Technologies, Tools, and Methods for Vision Research NOT-EY-23-005 NEI Apr 3, 2023 Feb 16, 2026 R41/R42, R43/R44, R21
Notice of Special Interest (NOSI): Promoting Language and Communication in Minimally Verbal/Non-Speaking Individuals with Autism NOT-DC-23-009 NIDCD Apr 3, 2023 Jun 6, 2026 R13, R15, R01, U01, R21, R43/R44, R41/R42, R03
Notice of Special Interest (NOSI): Advancing Research Needed to Develop a Coccidioidomycosis (Valley fever) Vaccine NOT-AI-23-031 NIAID Feb 23, 2023 Jan 15, 2026 R01, R41/R42, R43/R44, R21, U44
Notice of Special Interest (NOSI): Small Business Digital Technologies for Early Detection, Characterization and Monitoring of Senescence-Related Changes NOT-AG-23-004 NIA Feb 7, 2023 Jan 6, 2026 R43/R44, R41/R42
Notice of Special Interest (NOSI): Development of Functional Assay Sites to Evaluate Candidate -Omics Variants Associated with Heart, Lung, Blood, or Sleep Disease (R01, R41, R42, R43, R44) NOT-HL-23-066 NHLBI Jan 31, 2023 Sep 8, 2026 R41/R42, R43/R44, R01
Notice of Special Interest (NOSI): Optimization of Data Storage and Utilization for the Sequence Read Archive (SRA) NOT-GM-23-015 NIGMS , NLM , ODSS Dec 14, 2022 Dec 19, 2025 R41/R42, R43/R44, R01, K08, RM1, R21, K25, K99/R00, K23, F30, F32, F33, F31, R16, R35, R15
Notice of Special Interest (NOSI): Advancing Research Needed to Develop a Coccidioidomycosis (Valley fever) Vaccine NOT-AI-23-007 NIAID Nov 25, 2022 Jan 8, 2026 R21, R41/R42, R43/R44, R01
Notice of Special Interest (NOSI): Advancing Research for Tickborne Diseases (TBDs) NOT-AI-23-013 NIAID , NIAMS , NIMH , NINDS Nov 25, 2022 Jan 8, 2026 R43/R44, R15, R01, R21, R03, R41/R42
Notice of Special Interest (NOSI): Advancing Development of Rapid Point-of-Care Hepatitis C Virus Diagnostics NOT-AI-23-001 NIAID , NCI , NIBIB Nov 23, 2022 Jan 8, 2026 R01, R41/R42, R43/R44, R21
Notice of Special Interest (NOSI): Utilization of Cohorts and Prospective Study Designs for Liquid Biopsy Assay Validation for Early Detection of Cancers NOT-CA-23-004 NCI Oct 17, 2022 Jul 2, 2025 R43/R44, R21, R01, UH2/UH3, R41/R42, U01
Notice of Special Interest (NOSI): Towards Developing a Cure for HBV in HIV/HBV Co-Infection NOT-AI-22-043 NIAID Apr 29, 2022 May 8, 2025 R01, R41/R42, R21, R43/R44
Notice of Special Interest (NOSI): Advancing NEI AGI Research on newly Identified Factors Into Models of Visual System Regeneration NOT-EY-22-002 NEI Jan 10, 2022 Feb 10, 2025 R43/R44, R21, R15, R41/R42, R01, R24
Notice of Special Interest (NOSI): Epidemiology and Prevention of Alcohol Misuse in Understudied Young Adult Populations; Military, Workforce, and Community College NOT-AA-22-001 NIAAA Dec 9, 2021 Sep 9, 2025 R21, R03, R01, R43/R44, R41/R42
Notice of Special Interest (NOSI): Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42, R43/R44 Clinical Trial Not Allowed) NOT-DE-21-012 NIDCR Sep 1, 2021 Sep 5, 2025 R43/R44, R41/R42

Expired NOSIs

Title Notice Number Organization Release
Date		 Expiration
Date		 Activity
Code(s)
Notice of Special Interest (NOSI): Advancing Genomic Technology Development for Research and Clinical Application NOT-HG-24-012 NHGRI Dec 20, 2023 Sep 30, 2024 R01, R21, R43/R44, R41/R42
Notice of Special Interest (NOSI): Quantum Sensing in Biomedical Applications (SBIR/STRR) NOT-EY-23-009 NEI NCATS NCI Sep 6, 2023 Sep 6, 2024 R43/R44, R41/R42
Notice of Special Interest (NOSI): Research Addressing Eye and Vision Health Equity/Health Disparities NOT-EY-22-004 NEI NIMHD Feb 14, 2022 Jan 25, 2025 R01, UG1, F31, R21, 333, K99/R00, K08, F30, K23, R43/R44, R34, R41/R42, F32
Notice of Special Interest: Research on Pain, Pain Management, and Opioids in Aging NOT-AG-22-004 NIA Dec 22, 2021 Jan 8, 2025 F31, P01, K99/R00, K08, R01, K01, R43/R44, F32, 332, F33, F99/K00, R15, K24, R21, K02, K25, R25, F30, K23, R36, R41/R42, SB1, K76, K22, K07, R13, R21/R33, U19
Notice of Special Interest (NOSI): Methods Development for Genomic Studies of Genetic Variation, Function, and Disease NOT-HG-22-007 NHGRI Dec 9, 2021 Nov 5, 2024 R41/R42, R01, R43/R44, R21
Notice of Special Interest (NOSI): Genomics Education Interactive Digital Media Resources (SBIR/STTR) NOT-HG-21-038 NHGRI Aug 26, 2021 Dec 31, 2024 R43/R44, R41/R42
Notice of Special Interest (NOSI): National Cancer Institute SBIR/STTR Program Announcement Regarding Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings NOT-CA-21-062 NCI Jul 23, 2021 Sep 7, 2024 R43/R44, R41/R42
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