PA-21-110 - Pilot and Feasibility Studies in Preparation for Substance Use Prevention Trials (R34 Clinical Trial Optional) is used for the submission of applications to the following Notices of Special Interest (NOSIs)

Active NOSIs

Title Notice Number Organization Release
Date
Expiration
Date
Activity
Code(s)
Notice of Special Interest: Advancing mHealth Interventions for Understanding and Preventing Alcohol-Related Domestic Violence NOT-AA-23-003 NIAAA Mar 6, 2023 Sep 8, 2026 R01, R21, R34, K99/R00
Notice of Special Interest (NOSI): Priority Research Opportunities in Crisis Response Services NOT-MH-23-140 NIMH , NIDA , ORWH Jan 18, 2023 May 8, 2025 R21, R01, R34
Notice of Special Interest (NOSI): Firearm Injury and Mortality Prevention Research NOT-OD-23-039 OBSSR , NCCIH , NIA , NIAAA , NICHD , NIDA , NIMH , NIMHD , NINR , ODP , ORWH , SGMRO Dec 16, 2022 Feb 5, 2026 R01, R34, R21, U24, R61/R33, UG3/UH3
Notice of Special Interest (NOSI): Addressing Evidence Gaps in Screening NOT-OD-22-179 ODP , NIA , NIAAA , NIAMS , NICHD , NIDA , NIDCD , NIDCR , NIMH , NIMHD , NINDS , NINR , ODS , ORWH , SGMRO Jul 14, 2022 May 8, 2025 R21, R01, R61/R33, UG3/UH3, R34, U01
Notice of Special Interest (NOSI): Research on Addressing Violence to Improve Health Outcomes NOT-OD-22-167 OBSSR , NIA , NIAAA , NICHD , NIDA , NIDCD , NIDCR , NIMH , NIMHD , NINR , ODP , ORWH , SGMRO Jul 8, 2022 Oct 5, 2025 R21, R01, R34, UG3/UH3
Notice of Special Interest (NOSI): Preventive Interventions to Address Cardiometabolic Risk Factors in Populations that Experience Health Disparities NOT-OD-22-154 ODP , NCI , NHLBI , NIAAA , NIAMS , NIDCR , NIEHS , NIMHD , NINDS , OBSSR , ORWH Jun 14, 2022 Oct 6, 2025 R01, R21, R34, R03, UG3/UH3
Notice of Special Interest (NOSI): Addressing Evidence Gaps in Screening NOT-OD-22-107 ODP , NIA , NIAAA , NIAMS , NICHD , NIDA , NIDCD , NIDCR , NIMH , NIMHD , NINDS , NINR , ODS , ORWH , SGMRO May 12, 2022 May 8, 2025 333, R01, R34, R21, R61/R33, U01, UG3/UH3
Notice of Special Interest (NOSI): Priority Research Opportunities in Crisis Response Services NOT-MH-22-110 NIMH , NIDA , ORWH Feb 8, 2022 May 8, 2025 R21, R01, R34, R43/R44
Notice of Special Interest (NOSI): Research to Prevent Drug Use, Misuse and Addiction NOT-DA-23-001 NIDA , ODP Jan 21, 2022 May 8, 2025 R01, R21, R34, R03
Notice of Special Interest (NOSI): Electronic Nicotine Delivery Systems (ENDS) and Alternative Nicotine and Tobacco Delivery Systems: Population, Clinical and Applied Prevention Mechanisms of Health Effects NOT-OD-22-023 ODP , NCI , NIDA , NIMHD , NIDCR Dec 8, 2021 May 9, 2024 R21, R01, 333, R34, R03, R61/R33
Notice of Special Interest (NOSI): Reducing Stigma Related to Drug Use in Human Service Settings NOT-DA-21-060 NIDA , NIMH Nov 18, 2021 Jan 8, 2025 R34, R01, DP1, DP2

Expired NOSIs

Title Notice Number Organization Release
Date
Expiration
Date
Activity
Code(s)
Notice of Special Interest (NOSI): Research on the Health of Bisexual and Bisexual+ People NOT-OD-22-166 OD NCCIH NIA NIAAA NIAID NICHD NIDA NIDCR NIMH NIMHD NINDS ODP Aug 11, 2022 Sep 8, 2023 K24, U01, R01, K01, R15, R03, K76, R34, K99/R00, T32, F32, UG3/UH3, R21, K23, F31
Notice of Special Interest (NOSI): Electronic Nicotine Delivery Systems (ENDS) and Alternative Nicotine and Tobacco Delivery Systems: Population, Clinical and Applied Prevention Mechanisms of Health Effects NOT-OD-21-137 ODP NIMHD NCI NIDA NIDCR Jun 28, 2021 Dec 8, 2021 333, R34, R01, R21, R03
Notice of Special Interest (NOSI): Research on Strategies to Enhance Mental Health Interventions and Services within Employment and Job Training Settings NOT-MH-21-230 NIMH NIDA Apr 16, 2021 Sep 8, 2023 R01, R34, R43/R44, R21
Notice of Special Interest (NOSI): Research on Co-morbid Substance Use, Substance Use Disorders, and Other Psychiatric Disorders NOT-DA-20-004 NIDA ORWH Jun 4, 2020 May 8, 2023 R34, R21, R03, R01


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