PA-22-178 - PHS 2022-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)
is used for the submission of applications to the following Notices of Special Interest (NOSIs)
Active NOSIs
| Title |
Notice Number |
Organization |
Release
Date |
Expiration
Date |
Activity
Code(s) |
| Notice of Special Interest (NOSI): Next-Generation Approaches to Renal Replacement Therapy Including Vascular Access |
NOT-DK-23-015 |
NIDDK , NCATS , NIBIB
|
Aug 14, 2023 |
Apr 7, 2025
|
R41/R42, R43/R44 |
| Notice of Special Interest (NOSI): Advancing Biomedical Research in Pulmonary Non-Tuberculous Mycobacterial (NTM) Infections |
NOT-AI-23-050 |
NIAID
|
Jun 27, 2023 |
Jul 17, 2026
|
R21, R41/R42, R43/R44, R01, U44 |
| Notice of Special Interest (NOSI): Using Targeted Degradation of Protein and non-Protein Targets for the Development of Novel Anti-Infectives |
NOT-AI-23-049 |
NIAID
|
Jun 23, 2023 |
Jul 17, 2026
|
R03, R01, R41/R42, R43/R44, R21 |
| Notice of Special Interest (NOSI): Promoting Research and Development of Vaccines Against Enteric Viruses |
NOT-AI-23-048 |
NIAID
|
Jun 15, 2023 |
Jul 17, 2026
|
R01, R43/R44, U44, R41/R42, R21 |
| Notice of Special Interest (NOSI): Developmentally Tailored HIV Prevention and Care Research for Adolescents and Young Adults |
NOT-MH-23-250 |
NIMH
|
May 19, 2023 |
Sep 8, 2026
|
K43, R41/R42, R21, K08, R25, K99/R00, T32, K01, F30, R34, R03, F31, R15, R43/R44, K24, K23, F32, R01 |
| Notice of Special Interest (NOSI): Synthetic Biology for Biomedical Applications. |
NOT-EB-23-002 |
NIBIB , NCCIH , NCI , NHLBI , NIA , NIAID , NICHD , NIGMS
|
Apr 14, 2023 |
May 17, 2026
|
R01, R21, R35, R41/R42, R43/R44 |
| Notice of Special Interest (NOSI): Development of Innovative Informatics and Data Science Technologies, Tools, and Methods for Vision Research |
NOT-EY-23-005 |
NEI
|
Apr 3, 2023 |
Feb 16, 2026
|
R41/R42, R43/R44, R21 |
| Notice of Special Interest (NOSI): Promoting Language and Communication in Minimally Verbal/Non-Speaking Individuals with Autism |
NOT-DC-23-009 |
NIDCD
|
Apr 3, 2023 |
Jun 6, 2026
|
R13, R15, R01, U01, R21, R43/R44, R41/R42, R03 |
| Notice of Special Interest (NOSI): Advancing Research Needed to Develop a Coccidioidomycosis (Valley fever) Vaccine |
NOT-AI-23-031 |
NIAID
|
Feb 23, 2023 |
Jan 15, 2026
|
R01, R41/R42, R43/R44, R21, U44 |
| Notice of Special Interest (NOSI): Small Business Digital Technologies for Early Detection, Characterization and Monitoring of Senescence-Related Changes |
NOT-AG-23-004 |
NIA
|
Feb 7, 2023 |
Jan 6, 2026
|
R43/R44, R41/R42 |
| Notice of Special Interest (NOSI): Development of Functional Assay Sites to Evaluate Candidate -Omics Variants Associated with Heart, Lung, Blood, or Sleep Disease (R01, R41, R42, R43, R44) |
NOT-HL-23-066 |
NHLBI
|
Jan 31, 2023 |
Sep 8, 2026
|
R41/R42, R43/R44, R01 |
| Notice of Special Interest (NOSI): Optimization of Data Storage and Utilization for the Sequence Read Archive (SRA) |
NOT-GM-23-015 |
NIGMS , NLM , ODSS
|
Dec 14, 2022 |
Dec 19, 2025
|
R41/R42, R43/R44, R01, K08, RM1, R21, K25, K99/R00, K23, F30, F32, F33, F31, R16, R35, R15 |
| Notice of Special Interest (NOSI): Advancing Research Needed to Develop a Coccidioidomycosis (Valley fever) Vaccine |
NOT-AI-23-007 |
NIAID
|
Nov 25, 2022 |
Jan 8, 2026
|
R21, R41/R42, R43/R44, R01 |
| Notice of Special Interest (NOSI): Advancing Research for Tickborne Diseases (TBDs) |
NOT-AI-23-013 |
NIAID , NIAMS , NIMH , NINDS
|
Nov 25, 2022 |
Jan 8, 2026
|
R43/R44, R15, R01, R21, R03, R41/R42 |
| Notice of Special Interest (NOSI): Advancing Development of Rapid Point-of-Care Hepatitis C Virus Diagnostics |
NOT-AI-23-001 |
NIAID , NCI , NIBIB
|
Nov 23, 2022 |
Jan 8, 2026
|
R01, R41/R42, R43/R44, R21 |
| Notice of Special Interest (NOSI): Utilization of Cohorts and Prospective Study Designs for Liquid Biopsy Assay Validation for Early Detection of Cancers |
NOT-CA-23-004 |
NCI
|
Oct 17, 2022 |
Jul 2, 2025
|
R43/R44, R21, R01, UH2/UH3, R41/R42, U01 |
| Notice of Special Interest (NOSI): Towards Developing a Cure for HBV in HIV/HBV Co-Infection |
NOT-AI-22-043 |
NIAID
|
Apr 29, 2022 |
May 8, 2025
|
R01, R41/R42, R21, R43/R44 |
| Notice of Special Interest (NOSI): Technological Innovations for Advancing Clinical SPECT Imaging |
NOT-EB-22-006 |
NIBIB
|
Mar 21, 2022 |
May 8, 2024
|
R21, F30, K01, R13, K23, K25, R43/R44, K08, R01, K99/R00, R41/R42, F32, R03, F31 |
| Notice of Special Interest (NOSI): Research Addressing Eye and Vision Health Equity/Health Disparities |
NOT-EY-22-004 |
NEI , NIMHD
|
Feb 14, 2022 |
Jan 25, 2025
|
R01, UG1, F31, R21, 333, K99/R00, K08, F30, K23, R43/R44, R34, R41/R42, F32 |
| Notice of Special Interest (NOSI): Addressing Accessibility Inequities with COVID Home-Based Testing for Individuals with Visual Impairment |
NOT-EY-22-010 |
NEI
|
Feb 4, 2022 |
Mar 9, 2024
|
R41/R42, R15, 333, R01, R43/R44, R21 |
| Notice of Special Interest (NOSI): Validation of Digital Health and Artificial Intelligence Tools for Improved Assessment in Epidemiological, Clinical, and Intervention Research |
NOT-CA-22-037 |
NCI , NHLBI , NIA , NIDA , NIMH , NINR , OBSSR
|
Jan 27, 2022 |
Mar 9, 2024
|
R01, R03, R21, R43/R44, R41/R42, R33, R34, R61/R33 |
| Notice of Special Interest (NOSI): Advancing NEI AGI Research on newly Identified Factors Into Models of Visual System Regeneration |
NOT-EY-22-002 |
NEI
|
Jan 10, 2022 |
Feb 10, 2025
|
R43/R44, R21, R15, R41/R42, R01, R24 |
| Notice of Special Interest (NOSI): Advancing Innovative Non-invasive Physiologic Monitoring To Improve Fetal Assessment |
NOT-HD-21-053 |
NICHD
|
Dec 28, 2021 |
May 8, 2024
|
R03, R01, R41/R42, R43/R44, R21 |
| Notice of Special Interest: Research on Pain, Pain Management, and Opioids in Aging |
NOT-AG-22-004 |
NIA
|
Dec 22, 2021 |
Jan 8, 2025
|
F31, P01, K99/R00, K08, R01, K01, R43/R44, F32, 332, F33, F99/K00, R15, K24, R21, K02, K25, R25, F30, K23, R36, R41/R42, SB1, K76, K22, K07, R13, R21/R33, U19 |
| Notice of Special Interest (NOSI): Methods Development for Genomic Studies of Genetic Variation, Function, and Disease |
NOT-HG-22-007 |
NHGRI
|
Dec 9, 2021 |
Nov 5, 2024
|
R41/R42, R01, R43/R44, R21 |
| Notice of Special Interest (NOSI): Epidemiology and Prevention of Alcohol Misuse in Understudied Young Adult Populations; Military, Workforce, and Community College |
NOT-AA-22-001 |
NIAAA
|
Dec 9, 2021 |
Sep 9, 2025
|
R21, R03, R01, R43/R44, R41/R42 |
| Notice of Special Interest (NOSI): Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42, R43/R44 Clinical Trial Not Allowed) |
NOT-DE-21-012 |
NIDCR
|
Sep 1, 2021 |
Sep 5, 2025
|
R43/R44, R41/R42 |
| Notice of Special Interest (NOSI): Genomics Education Interactive Digital Media Resources (SBIR/STTR) |
NOT-HG-21-038 |
NHGRI
|
Aug 26, 2021 |
Dec 31, 2024
|
R43/R44, R41/R42 |
| Notice of Special Interest (NOSI): National Cancer Institute SBIR/STTR Program Announcement Regarding Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings |
NOT-CA-21-062 |
NCI
|
Jul 23, 2021 |
Sep 7, 2024
|
R43/R44, R41/R42 |
| Notice of Special Interest (NOSI): Navigating Pediatric to Adult Health Care: Lost in Transition |
NOT-HD-21-027 |
NICHD , NIAAA , NCI , NIMH , NIAMS , OBSSR , NIBIB , NIDCR
|
Jun 22, 2021 |
Jan 8, 2024
|
R01, R21, R43/R44, R41/R42 |
| Notice of Special Interest (NOSI): HIV Drug Resistance Assays and Actionable Data Dissemination Strategies |
NOT-AI-21-056 |
NIAID , NIDA
|
Jun 17, 2021 |
May 8, 2024
|
R01, R21, U01, U24, R41/R42, R43/R44 |
| Notice of Special Interest: NIDCD Health Disparities and Inequities Research |
NOT-DC-21-003 |
NIDCD , SGMRO
|
Jun 11, 2021 |
May 8, 2024
|
R01, R21, P50, F30, F31, F32, F99/K00, K01, K08, K18, K23, K24, K25, K99/R00, 333, R41/R42, R43/R44 |
| Notice of Special Interest (NOSI): Improving Patient Adherence to Treatment and Prevention Regimens to Promote Health |
NOT-OD-21-100 |
OBSSR , NIMHD , NIDA , NIMH , ORWH , NIDCD , SGMRO , ODP , NIA , NHLBI , NCI , NINR , NCCIH , NEI , NICHD
|
Apr 8, 2021 |
Jun 8, 2024
|
R01, R21, R03, R41/R42, R43/R44, R21/R33, UG3/UH3, R34 |
| Notice of Special Interest (NOSI): Translation of BRAIN Initiative Technologies to the Marketplace |
NOT-MH-21-125 |
NIMH , NIA , NIAAA , NIBIB , NINDS , NIDA , NEI , NCCIH , NICHD , NIDCD
|
Mar 3, 2021 |
Jan 6, 2024
|
R43/R44, R41/R42 |
| Notice of Special Interest (NOSI): Hearing Healthcare for Adults: Improving Access and Affordability |
NOT-DC-21-001 |
NIDCD
|
Feb 16, 2021 |
Jan 8, 2024
|
R01, R21, U01, R43/R44, R41/R42 |
| Notice of Special Interest (NOSI): Understanding the effects of cancer and cancer treatment on aging trajectories and aging outcomes |
NOT-CA-21-031 |
NCI , NIA
|
Jan 27, 2021 |
Jan 8, 2024
|
R21, R03, R01, U01, P01, K99/R00, K08, R43/R44, R41/R42, R13, R21/R33, K01, K23 |
| Notice of Special Interest (NOSI): Development and/or Validation of Devices or Electronic Systems to Monitor or Enhance Mind and Body Interventions (SBIR/STTR) |
NOT-AT-21-001 |
NCCIH
|
Oct 23, 2020 |
Jan 5, 2024
|
R41/R42, R43/R44 |
Expired NOSIs
| Title |
Notice Number |
Organization |
Release
Date |
Expiration
Date |
Activity
Code(s) |
| Notice of Special Interest (NOSI): Advancing Research for Amyotrophic Lateral Sclerosis (ALS) |
NOT-NS-23-062 |
NINDS
|
Feb 6, 2023 |
Jun 24, 2023
|
R61/R33, R41/R42, R43/R44 |
| Notice of Special Interest (NOSI): Research to Support Regulatory Science on Infant Formula |
NOT-HD-22-016 |
NICHD OD ODS
|
Jun 13, 2022 |
May 8, 2023
|
R03, R41/R42, R43/R44, R01, 333, R21 |
| Notice of Special Interest (NOSI): Innovative Technologies to Improve Assessments, Interventions, and Outcomes for Individuals with Intellectual and Developmental Disabilities (R43/R44) |
NOT-HD-22-009 |
NICHD
|
Jun 7, 2022 |
Apr 6, 2023
|
R41/R42, R43/R44 |
| Notice of Special Interest (NOSI): Innovative Technologies for Research on Climate Change and Human Health Small Business Technology Transfer (R41/R42 Clinical Trial Optional) |
NOT-ES-22-009 |
NIEHS NCATS NEI NHLBI NIA NIAID NICHD NIMH NIMHD NINR
|
Jun 3, 2022 |
Apr 6, 2023
|
R41/R42 |
| Notice of Special Interest (NOSI): Small Business Initiatives for Innovative Diagnostic Technology for Improving Outcomes for Maternal Health |
NOT-EB-21-001 |
NIBIB NIAID ORWH NICHD NIMHD NIMH NINDS OD NCATS NHLBI NHGRI
|
Feb 22, 2021 |
Apr 6, 2023
|
R41/R42, R43/R44, 333 |
| Notice of Special Interest (NOSI) for the NEI Anterior Segment Initiative (ASI): Identification and Development of New Biomarkers and Effective methods to Diagnose Dry Eye Disease. |
NOT-EY-21-007 |
NEI
|
Dec 21, 2020 |
May 8, 2023
|
R01, R21, R43/R44, R41/R42 |
| Notice of Special Interest: Kidney Precision Medicine Technology Development and Translation |
NOT-DK-21-007 |
NIDDK
|
Dec 2, 2020 |
Sep 6, 2023
|
R43/R44, R41/R42 |
| Notice of Special Interest (NOSI): Research in the Emergency Setting |
NOT-NS-20-005 |
NINDS NCI NIDA NHLBI NIDCD NIAAA NICHD NIA NIGMS NEI NIMHD NIMH
|
Sep 8, 2020 |
Sep 8, 2022
|
R01, R21, R03, K01, K99/R00, K08, K23, R13, R43/R44, R41/R42, P01, U01, R34, R35, RM1 |
| Notice of Special Interest (NOSI): Methods Development in Natural Products Research (SBIR/STTR) |
NOT-AT-20-015 |
NCCIH
|
Jul 16, 2020 |
Sep 6, 2023
|
R41/R42, R43/R44 |
| Notice of Special Interest: NIGMS Priorities for Small Business Development of Sepsis Diagnostics and Therapeutics |
NOT-GM-20-028 |
NIGMS
|
Jun 2, 2020 |
Sep 12, 2023
|
R41/R42, R43/R44, SB1 |
|
NIH Grants and Funding
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