PA-22-178 - PHS 2022-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) is used for the submission of applications to the following Notices of Special Interest (NOSIs)

Active NOSIs

Title Notice Number Organization Release
Date
Expiration
Date
Activity
Code(s)
Notice of Special Interest (NOSI): Advancing Research Needed to Develop a Coccidioidomycosis (Valley fever) Vaccine NOT-AI-23-007 NIAID Nov 25, 2022 Jan 8, 2026 R21, R41/R42, R43/R44, R01
Notice of Special Interest (NOSI): Advancing Research for Tickborne Diseases (TBDs) NOT-AI-23-013 NIAID , NIAMS , NIMH , NINDS Nov 25, 2022 Jan 8, 2026 R43/R44, R15, R01, R21, R03, R41/R42
Notice of Special Interest (NOSI): Advancing Development of Rapid Point-of-Care Hepatitis C Virus Diagnostics NOT-AI-23-001 NIAID , NCI , NIBIB Nov 23, 2022 Jan 8, 2026 R01, R41/R42, R43/R44, R21
Notice of Special Interest (NOSI): Utilization of Cohorts and Prospective Study Designs for Liquid Biopsy Assay Validation for Early Detection of Cancers NOT-CA-23-004 NCI Oct 17, 2022 Jul 2, 2025 R43/R44, R21, R01, UH2/UH3, R41/R42, U01
Notice of Special Interest (NOSI): Research to Support Regulatory Science on Infant Formula NOT-HD-22-016 NICHD , OD , ODS Jun 13, 2022 May 8, 2023 R03, R41/R42, R43/R44, R01, 333, R21
Notice of Special Interest (NOSI): Innovative Technologies to Improve Assessments, Interventions, and Outcomes for Individuals with Intellectual and Developmental Disabilities (R43/R44) NOT-HD-22-009 NICHD Jun 7, 2022 Apr 6, 2023 R41/R42, R43/R44
Notice of Special Interest (NOSI): Innovative Technologies for Research on Climate Change and Human Health Small Business Technology Transfer (R41/R42 Clinical Trial Optional) NOT-ES-22-009 NIEHS , NCATS , NEI , NHLBI , NIA , NIAID , NICHD , NIMH , NIMHD , NINR Jun 3, 2022 Apr 6, 2023 R41/R42
Notice of Special Interest (NOSI): Towards Developing a Cure for HBV in HIV/HBV Co-Infection NOT-AI-22-043 NIAID Apr 29, 2022 May 8, 2025 R01, R41/R42, R21, R43/R44
Notice of Special Interest (NOSI): Technological Innovations for Advancing Clinical SPECT Imaging NOT-EB-22-006 NIBIB Mar 21, 2022 May 8, 2024 R21, F30, K01, R13, K23, K25, R43/R44, K08, R01, K99/R00, R41/R42, F32, R03, F31
Notice of Special Interest (NOSI): Research Addressing Eye and Vision Health Equity/Health Disparities NOT-EY-22-004 NEI , NIMHD Feb 14, 2022 Jan 25, 2025 R01, UG1, F31, R21, 333, K99/R00, K08, F30, K23, R43/R44, R34, R41/R42, F32
Notice of Special Interest (NOSI): Addressing Accessibility Inequities with COVID Home-Based Testing for Individuals with Visual Impairment NOT-EY-22-010 NEI Feb 4, 2022 Mar 9, 2024 R41/R42, R15, 333, R01, R43/R44, R21
Notice of Special Interest (NOSI): Validation of Digital Health and Artificial Intelligence Tools for Improved Assessment in Epidemiological, Clinical, and Intervention Research NOT-CA-22-037 NCI , NHLBI , NIA , NIDA , NIMH , NINR , OBSSR Jan 27, 2022 Mar 9, 2024 R01, R03, R21, R43/R44, R41/R42, R33, R34, R61/R33
Notice of Special Interest (NOSI): Advancing NEI AGI Research on newly Identified Factors Into Models of Visual System Regeneration NOT-EY-22-002 NEI Jan 10, 2022 Feb 10, 2025 R43/R44, R21, R15, R41/R42, R01, R24
Notice of Special Interest (NOSI): Advancing Innovative Non-invasive Physiologic Monitoring To Improve Fetal Assessment NOT-HD-21-053 NICHD Dec 28, 2021 May 8, 2024 R03, R01, R41/R42, R43/R44, R21
Notice of Special Interest: Research on Pain, Pain Management, and Opioids in Aging NOT-AG-22-004 NIA Dec 22, 2021 Jan 8, 2025 F31, P01, K99/R00, K08, R01, K01, R43/R44, F32, 332, F33, F99/K00, R15, K24, R21, K02, K25, R25, F30, K23, R36, R41/R42, SB1, K76, K22, K07, R13, R21/R33, U19
Notice of Special Interest (NOSI): Methods Development for Genomic Studies of Genetic Variation, Function, and Disease NOT-HG-22-007 NHGRI Dec 9, 2021 Nov 5, 2024 R41/R42, R01, R43/R44, R21
Notice of Special Interest (NOSI): Epidemiology and Prevention of Alcohol Misuse in Understudied Young Adult Populations; Military, Workforce, and Community College NOT-AA-22-001 NIAAA Dec 9, 2021 Sep 9, 2025 R21, R03, R01, R43/R44, R41/R42
Notice of Special Interest (NOSI): Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42, R43/R44 Clinical Trial Not Allowed) NOT-DE-21-012 NIDCR Sep 1, 2021 Sep 5, 2025 R43/R44, R41/R42
Notice of Special Interest (NOSI): Genomics Education Interactive Digital Media Resources (SBIR/STTR) NOT-HG-21-038 NHGRI Aug 26, 2021 Dec 31, 2024 R43/R44, R41/R42
Notice of Special Interest (NOSI): National Cancer Institute SBIR/STTR Program Announcement Regarding Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings NOT-CA-21-062 NCI Jul 23, 2021 Sep 7, 2024 R43/R44, R41/R42
Notice of Special Interest (NOSI): Navigating Pediatric to Adult Health Care: Lost in Transition NOT-HD-21-027 NICHD , NIAAA , NCI , NIMH , NIAMS , OBSSR , NIBIB , NIDCR Jun 22, 2021 Jan 8, 2024 R01, R21, R43/R44, R41/R42
Notice of Special Interest (NOSI): HIV Drug Resistance Assays and Actionable Data Dissemination Strategies NOT-AI-21-056 NIAID , NIDA Jun 17, 2021 May 8, 2024 R01, R21, U01, U24, R41/R42, R43/R44
Notice of Special Interest: NIDCD Health Disparities and Inequities Research NOT-DC-21-003 NIDCD , SGMRO Jun 11, 2021 May 8, 2024 R01, R21, P50, F30, F31, F32, F99/K00, K01, K08, K18, K23, K24, K25, K99/R00, 333, R41/R42, R43/R44
Notice of Special Interest (NOSI): Improving Patient Adherence to Treatment and Prevention Regimens to Promote Health NOT-OD-21-100 OBSSR , NIMHD , NIDA , NIMH , ORWH , NIDCD , SGMRO , ODP , NIA , NHLBI , NCI , NINR , NCCIH , NEI , NICHD Apr 8, 2021 Jun 8, 2024 R01, R21, R03, R41/R42, R43/R44, R21/R33, UG3/UH3, R34
Notice of Special Interest (NOSI): Translation of BRAIN Initiative Technologies to the Marketplace NOT-MH-21-125 NIMH , NIA , NIAAA , NIBIB , NINDS , NIDA , NEI , NCCIH , NICHD , NIDCD Mar 3, 2021 Jan 6, 2024 R43/R44, R41/R42
Notice of Special Interest (NOSI): Small Business Initiatives for Innovative Diagnostic Technology for Improving Outcomes for Maternal Health NOT-EB-21-001 NIBIB , NIAID , ORWH , NICHD , NIMHD , NIMH , NINDS , OD , NCATS , NHLBI , NHGRI Feb 22, 2021 Apr 6, 2023 R41/R42, R43/R44, 333
Notice of Special Interest (NOSI): Hearing Healthcare for Adults: Improving Access and Affordability NOT-DC-21-001 NIDCD Feb 16, 2021 Jan 8, 2024 R01, R21, U01, R43/R44, R41/R42
Notice of Special Interest (NOSI): Understanding the effects of cancer and cancer treatment on aging trajectories and aging outcomes NOT-CA-21-031 NCI , NIA Jan 27, 2021 Jan 8, 2024 R21, R03, R01, U01, P01, K99/R00, K08, R43/R44, R41/R42, R13, R21/R33, K01, K23
Notice of Special Interest (NOSI) for the NEI Anterior Segment Initiative (ASI): Identification and Development of New Biomarkers and Effective methods to Diagnose Dry Eye Disease. NOT-EY-21-007 NEI Dec 21, 2020 May 8, 2023 R01, R21, R43/R44, R41/R42
Notice of Special Interest: Kidney Precision Medicine Technology Development and Translation NOT-DK-21-007 NIDDK Dec 2, 2020 Sep 6, 2023 R43/R44, R41/R42
Notice of Special Interest (NOSI): Development and/or Validation of Devices or Electronic Systems to Monitor or Enhance Mind and Body Interventions (SBIR/STTR) NOT-AT-21-001 NCCIH Oct 23, 2020 Jan 5, 2024 R41/R42, R43/R44
Notice of Special Interest (NOSI): Methods Development in Natural Products Research (SBIR/STTR) NOT-AT-20-015 NCCIH Jul 16, 2020 Sep 6, 2023 R41/R42, R43/R44
Notice of Special Interest: NIGMS Priorities for Small Business Development of Sepsis Diagnostics and Therapeutics NOT-GM-20-028 NIGMS Jun 2, 2020 Sep 12, 2023 R41/R42, R43/R44, SB1

Expired NOSIs

Title Notice Number Organization Release
Date
Expiration
Date
Activity
Code(s)
Notice of Special Interest (NOSI): Research in the Emergency Setting NOT-NS-20-005 NINDS NCI NIDA NHLBI NIDCD NIAAA NICHD NIA NIGMS NEI NIMHD NIMH Sep 8, 2020 Sep 8, 2022 R01, R21, R03, K01, K99/R00, K08, K23, R13, R43/R44, R41/R42, P01, U01, R34, R35, RM1


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