PA-21-219 - Joint NINDS/NIMH Exploratory Neuroscience Research Grant (R21 Clinical Trial Optional) is used for the submission of applications to the following Notices of Special Interest (NOSIs)

Active NOSIs

Title Notice Number Organization Release
Date
Expiration
Date
Activity
Code(s)
Notice of Special Interest (NOSI): Research Related to Neuroethical Considerations for Neurological Diseases NOT-NS-24-073 NINDS Jul 9, 2024 Oct 16, 2027 R03, R21, R01
Notice of Special Interest (NOSI): Research Opportunities Centering the Health of Women Across the HIV Research Continuum NOT-OD-24-119 ORWH , FIC , NCCIH , NCI , NIA , NIAAA , NIAID , NIAMS , NICHD , NIDA , NIDDK , NIMH , NIMHD , NINDS , OAR , OBSSR , SGMRO May 21, 2024 Jan 8, 2026 K99/R00, R01, R34, F32, K23, K25, K02, R15, K01, K43, R21, K24, R61/R33, K08, F30, R03, DP1, U34, F31, T32, R36
Notice of Special Interest (NOSI): Fundamental Mechanisms and Functions of Co-transmission in the Brain NOT-MH-24-105 NIMH , NIAAA , NIDA Jan 2, 2024 Feb 4, 2027 R03, R21, P50, R01, R15
Notice of Special Interest (NOSI): Neuromodulatory Control of Circuits Underlying Mental Health Relevant Behaviors NOT-MH-24-100 NIMH Jan 2, 2024 May 10, 2027 R15, R01, P50, R21, R03
Notice of special interest (NOSI): Adopting Techniques and Tools Developed from the BRAIN Initiative Toward NIMH Strategic Research Priorities NOT-MH-24-290 NIMH Oct 25, 2023 May 10, 2027 P50, R01, R21, R03, R15
Notice of Special Interest (NOSI): Neuropathogenesis of CNS Complications Associated with HIV NOT-MH-23-280 NIMH , NINDS Jun 15, 2023 Sep 8, 2026 K24, K08, R01, K01, K23, R15, K99/R00, F30, F32, K43, F31, T32, R03, R21, R25
Notice of Special Interest (NOSI): Eradication of HIV-1 from Central Nervous System Reservoirs NOT-MH-23-260 NIMH , NINDS Jun 15, 2023 Sep 8, 2026 R21, K43, K01, R25, K08, K99/R00, R01, F30, F32, T32, R03, R15, F31, K23, K24
Notice of Special Interest (NOSI): Clinical Studies of CNS Complications in People with HIV NOT-MH-23-255 NIMH , NINDS Jun 15, 2023 Sep 8, 2026 K43, K01, R25, K99/R00, R21, K08, F30, T32, R01, F32, F31, R03, R15, K23, K24
Notice of Special Interest (NOSI): The Neural Mechanisms of Multi-Dimensional Emotional and Social Representation NOT-MH-23-120 NIMH Dec 7, 2022 Jan 8, 2025 R21, R01, R03, R15
Notice of Special Interest (NOSI): Advancing Research for Tickborne Diseases (TBDs) NOT-AI-23-013 NIAID , NIAMS , NIMH , NINDS Nov 25, 2022 Jan 8, 2026 R43/R44, R15, R01, R21, R03, R41/R42
Notice of Special Interest (NOSI): Community-Based Participatory Research (CBPR) Initiative in Reducing and Eliminating Health Disparities with a focus on addressing diverse representation in research on Down syndrome (R21 Clinical Trial Optional) NOT-OD-22-142 OD , NCI , NEI , NHLBI , NIA , NIAMS , NICHD , NIDCD , NIDCR , NIMHD , NINDS Aug 5, 2022 Mar 17, 2025 R21
Notice of Special Interest: Tools to Enhance the Study of Prenatal and Pediatric Hydrocephalus NOT-NS-23-003 NINDS May 20, 2022 Dec 10, 2025 R21, R01
Notice of Special Interest: NIMH Priorities on Research on Aggression and Violence Against Others NOT-MH-22-095 NIMH Feb 3, 2022 Jan 8, 2025 R36, R01, R34, R21, F32, R21/R33, R03, R61/R33, U01, K08, R15, K23, P50, F30, K99/R00, F31, K22, K01
Notice of Special Interest: Neuro-Glia Mechanisms Governing Complex Behaviors (R01 Clinical Trial Optional) NOT-MH-22-090 NIMH Feb 3, 2022 May 8, 2025 R21, R01

Expired NOSIs

Title Notice Number Organization Release
Date
Expiration
Date
Activity
Code(s)
Notice of Special Interest (NOSI) in Migraine and Headache Research NOT-NS-22-051 NINDS Dec 27, 2021 May 8, 2022 U01, K01, UG3/UH3, K22, K99/R00, K02, K08, R01, F30, K23, F32, R21, F31, R61/R33
Notice of Special Interest (NOSI) in NINDS mission relevant Pain Research NOT-NS-22-050 NINDS Dec 27, 2021 May 8, 2022 K01, UG3/UH3, K99/R00, K22, K08, R01, K02, F30, K23, R21, F32, F31, U01, U24, R61/R33
Notice of Special Interest (NOSI): Adopting Techniques and Tools Developed from the BRAIN Initiative Toward NIMH Strategic Research Priorities NOT-MH-21-115 NIMH Dec 28, 2020 May 8, 2023 R01, R21, R15, P50
Notice of Special Interest (NOSI): Research in the Emergency Setting NOT-NS-20-005 NINDS NCI NIDA NHLBI NIDCD NIAAA NICHD NIA NIGMS NEI NIMHD NIMH Sep 8, 2020 Sep 8, 2022 R01, R21, R03, K01, K99/R00, K08, K23, R13, R43/R44, R41/R42, P01, U01, R34, R35, RM1


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