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Mentored Patient-Oriented Research (POR) Career Development Award

Purpose of the Award

  • Ensures a future cadre of well-trained scientists working in POR areas who will become competitive for NIH research project (R01) grant support.
  • Encourages research-oriented clinicians to develop independent research skills and gain experience in advanced methods and experimental approaches needed to become an independent investigator conducting patient-oriented research
  • Increases the pool of clinical researchers who can conduct patient-oriented studies, capitalizing on the discoveries of biomedical research and translating them to clinical settings
  • Supports the career development of investigators who have made a commitment to focus their research endeavors on patient-oriented research


  • New: NOT-OD-20-033
    • Program Plan attachment – candidates expected to address, as applicable, new research skills they plan to acquire in rigorous research design, experimental methods, quantitative approaches, and data analysis and interpretation.
    • Applicants for diversity-related career development programs expected to attach a Description of Candidate’s Contribution to Program Goals.
  • There are many legitimate reasons why an applicant would choose not to include a letter of reference from previous mentors such as their predoctoral thesis advisor, training residents, and/or fellows. The absence of a letter from a predoctoral thesis advisor or another previous mentor should not affect the score.


  • POR is defined as research conducted with human subjects (or on material of human origin such as tissues, specimens and cognitive phenomena) for which an investigator directly interacts with human subjects
  • Clinically trained professionals or individuals with a clinical degree who are interested in further career development in biomedical research that is not patient-oriented should refer to the Mentored Clinical Scientist Career Development Award (K08)

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