COVID-19

  • Coronavirus Disease 2019 (COVID-19): Information for NIH Applicants and Recipients of NIH Funding
  • Applicant/Recipient COVID-19 Update History
  • CDC COVID-19
  • Get the latest research information from NIH | Español
Expand for resources

n/a Warning! This browser is not supported - Some features might not work. Try using a different browser such as Chrome, Edge, Firefox, or Safari.

  • U.S. Department of Health & Human Services
  • National Institutes of Health
Grants Home
  • eRA  |  new windowwNIH Staff   |  Glossary  |  FAQs  |  Help
  • Home
  • About Grants
    • Grants Process Overview
    • Get Started

    • Learn the Basics
    • Plan Your Application
    • How to Apply

    • Prepare to Apply
    • Write Application
    • Submit
    • How to Apply Video Tutorials

      Application Referral and Review

    • Receipt and Referral
    • Peer Review
    • Pre-Award and Post-Award Processes

    • Pre-Award and Award Process
    • Post Award Monitoring and Reporting
    • Forms Library

      Information For

    • Researchers
    • Research Administrators
    • Reviewers
    • Small Businesses Link to External Site
    • Foreign Grants
    • Media and the Public
    • NIH Staff Lock Icon
  • Funding
    • Find Grant Funding (NIH Guide to Grants and Contracts)
    • Other Transactions
    • Contracts
    • Research Training and Career Development Link to External Site
    • Loan Repayment Programs Link to External Site
    • Extramural Diversity Link to External Site
    • NIH Funding Strategies




      Notice IconAvoid Grant Scams
  • Policy & Compliance
    • NIH Grants Policy Statement
    • Notices of Policy Changes
    • Compliance & Oversight
    • Policy Topics

    • Animal Welfare Link to External Site
    • Application Submission Policies
    • Clinical Trial Requirements
    • Coronavirus Disease 2019 (COVID-19)
    • Early Stage Investigator Policies
    • Family-Friendly Initiatives
    • Financial Conflict of Interest
    • Human Subjects Research
    • Inclusion Policies
    • Intellectual Property Policy
    • Lobbying Guidance for Grantee Activities
    • Natural Disasters
    • NIH Funding Strategies
    • Peer Review Policies and Practices
    • Protecting U.S. Biomedical Intellectual Innovation
    • Public Access Link to External Site
    • Research Integrity
    • Rigor and Reproducibility
    • Sharing Policies Link to External Site
    • Supporting a Safe and Respectful Workplace
  • News & Events

      Latest News

    • News Highlights
    • "Open Mike" Blog Link to External Site
    • Extramural Nexus Link to External Site
    • Subscribe and Follow

    • Listservs
    • Social Media

      Virtual Learning

    • Webinars
    • Podcasts
    • NIH Grants YouTube Channel Link to External Site

      Connect In Person

    • NIH Regional Seminars on Program
      Funding & Grants Administration
    • SBIR-STTR Engage & Connect Link to External Site
    • Loan Repayment Program (LRP)
      Contact & Engage
       Link to External Site
    • Office of Laboratory Animal Welfare (OLAW)
      Workshops and Conference
      Link to External Site
    • Events Calendar
  • About OER
    • About the Office of Extramural Research
    • OER Offices

    • Immediate Office of the Director (IMOD)
    • Office of Policy for Extramural Research Administration (OPERA)
    • Office of Research Reporting and Analysis (ORRA)
    • Office of Laboratory Animal Welfare (OLAW)
    • Strategic Management and Contracts Office (SMCO)
    • Office of Electronic Research Administration (eRA)
    • Division of Communication & Outreach (DCO)
    • Small Business Education and Entrepreneurial Development (SEED)
    • Division of Biomedical Research Workforce (DBRW)
    • Division of Human Subjects Research (DHSR)
  • eRA
    Link to External Site
  • NIH Staff Lock Icon
  • Home
  • FAQs
  • Help

Policy & Compliance

  • NIH Grants Policy Statement
  • Notices of Policy Changes
  • Compliance & Oversight
  • Select Policy Topics+
    • Animal Welfare
    • Application Submission Policies
    • Clinical Trial Requirements+
      • Clinical Trial Definition
      • Why the Changes
      • Good Clinical Practice
      • Specific Funding Opportunities
      • New Form
      • Single IRB Policy
      • Protocol Template
      • Registration and Reporting
    • NIH Funding Strategies
    • Human Subjects Research
    • Intellectual Property Policy
    • Lobbying Guidance for Grantee Activities
    • Early Stage and Early Established Investigator Policies
    • Peer Review Policies and Practices
    • Public Access
    • Research Integrity
    • Anti-Sexual Harassment
    • Sharing Policies
Home  »   Policy & Compliance   »  Office of Laboratory Animal Welfare   »  Office of Laboratory Animal Welfare - Adoption of the Guide for the Care and Use of Laboratory Animals: Eighth Edition
Office of Laboratory Animal Welfare (ARCHIVED - OLAW Policy & Guidance )

Please note that the documents on this page are for reference only. Although accurate when originally released, they may now contain out-of-date information, including broken hyperlinks. They remain solely for historical purposes and are not considered current guidance.

Adoption of the Guide for the Care and Use of Laboratory Animals: Eighth Edition

The NIH adopted the 8th Edition of the Guide for the Care and Use of Laboratory Animals (Guide) Link to Non-U.S. Government Site - Click for Disclaimer effective January 1, 2012. In OLAW's judgment, the 8th Edition of the Guide empowers continued advancement in the humane care and use of vertebrate animals in research, research training, and biological testing.

Position Statements

  • Position Statements: OLAW Responds to Concerns
    • These Position Statements describe how OLAW expects Assured institutions to implement the 8th Edition of the Guide. OLAW clarified the Position Statements in May 2012 in response to comments from the public about their understanding of the Position Statements.

  • Public Comments on Position Statements
    • View the comments submitted by individuals and organizations from December 1, 2011 to February 3, 2012 on their understanding of the Position Statements.

Background

  • Public Comments on Adoption of the Guide
    • View the comments submitted in spring 2011 by individuals and organizations on if the NIH should adopt the Guide and the proposed implementation plan.

  • Helpful Resources

    To assist Assured institutions in implementation of the 8th Edition of the Guide, OLAW has updated the following guidance resources and sample documents:

    • Frequently Asked Questions
    • Tutorial for PHS Policy
    • Annual Report to OLAW
    • Animal Welfare Assurances (Domestic, Foreign and Interinstitutional)
    • Semiannual Program Review and Facility Inspection Checklist
    • Semiannual Report to the Institutional Official
    • Animal Study Proposal

  • Federal Register Notices
    • June 26, 2012 Federal Register Notice (PDF - 200 KB): Clarification of Position Statements on Implementation of the Eighth Edition of the Guide for the Care and Use of Laboratory Animals.
    • December 1, 2011 Federal Register Notice (PDF - 148 KB): Adoption and Implementation of the Eighth Edition of the Guide for the Care and Use of Laboratory Animals.
    • May 11, 2011 Federal Register Notice (PDF - 180 KB): Proposed Adoption and Implementation of the Eighth Edition of the Guide for the Care and Use of Laboratory Animals. Notice of Additional Extension of Public Comment Period.
    • March 29, 2011 Federal Register Notice (PDF - 148 KB): Proposed Adoption and Implementation of the Eighth Edition of the Guide for the Care and Use of Laboratory Animals. Notice of Extension of Public Comment Period.
    • February 24, 2011 Federal Register Notice (PDF - 183 KB): Proposed Adoption and Implementation of the Eighth Edition of the Guide for the Care and Use of Laboratory Animals. Notice.
  • NIH Guide for Grants and Contracts Notices
    • NOT-OD-12-112: Clarification of Position Statements on Implementation of the Guide for the Care and Use of Laboratory Animals: Eighth Edition
    • NOT-OD-12-042: Extension of Comment Period on the Office of Laboratory Animal Welfare Position Statements 
    • NOT-OD-12-020: Adoption and Implementation of the Guide for the Care and Use of Laboratory Animals: Eighth Edition  
    • NOT-OD-11-082: Consideration of Public Comments on Proposed Adoption and Implementation of the Guide for the Care and Use of Laboratory Animals: Eighth Edition
    • NOT-OD-11-066: Additional Extension of Comment Period on Proposed Adoption and Implementation of the Guide for the Care and Use of Laboratory Animals: Eighth Edition and Removal of Character Limit for Comments
    • NOT-OD-11-056: Extended Comment Period on Proposed Adoption and Implementation of the Guide for the Care and Use of Laboratory Animals: Eighth Edition
    • NOT-OD-11-042: Public Comment Period Open on Proposed Adoption and Implementation of the Guide for the Care and Use of Laboratory Animals: Eighth Edition
    • NOT-OD-10-102: Update of the Guide for the Care and Use of Laboratory Animals


Note: For help accessing PDF, RTF, MS Word, Excel, PowerPoint, Audio or Video files, see Help Downloading Files.


This page last updated on June 26, 2012 
Technical Issues: E-mail OER Webmaster   

Back to Top
  • Contact Us
  • Bookmark & Share
  • E-mail Updates
  • RSS Feed
  • Podcast
  • Twitter
  • YouTube

  • Search
  • Help Downloading Files
  • Disclaimer
  • Older Versions of this Page
  • Privacy Notice
  • Accessibility
  • HHS Vulnerability Disclosure
  • FOIA
  • U.S. Department of Health and Human Services
  • Grants.gov
  • USA.gov - Government Made Easy


  • National Institutes of Health (NIH), 9000 Rockville Pike, Bethesda, Maryland 20892

  • NIH... Turning Discovery Into Health