Policy Notices

• OMB Single Audit Extension for Recipients in Major Disaster Areas (Alaska, Florida, South Carolina, North Carolina, Puerto Rico)
  (NOT-OD-23-022)
  National Institutes of Health
  

• Announcing New Inbox for Inquiries Related to Federal Financial Reports (FFRs) and Financial Closeout
  (NOT-OD-23-035)
  National Institutes of Health
  

General Notices

• Notice of Need to Expire and Reissue RFA-AT-23-006 Research Networks to Promote Multidisciplinary Mechanistic Studies on Music-Based Interventions for Pain/Alzheimers Disease/AD Related Dementias (U24 Clinical Trial Optional) to Correct Review Criteria
  (NOT-AT-23-005)
  National Center for Complementary and Integrative Health
  National Institute on Aging
  

• Notice of Pre-Application Webinar for the Pre-Competitive Collaboration on Liquid Biopsy for Early Cancer Assessment Program: RFA-CA-23-018 and RFA-CA-23-019
  (NOT-CA-23-022)
  National Cancer Institute
  

• Notice of NHLBI Participation in RFA-DA-23-059 "HEAL Initiative: Sleep Predictors of Opioid-Use Disorder Treatment Outcomes Program (R01 Clinical Trial Optional)"
  (NOT-HL-22-058)
  National Heart, Lung, and Blood Institute
  

• Notice of NHLBI Participation in RFA-DA-23-060 "HEAL Initiative - Sleep Predictors of Opioid-Use Disorder Treatment Outcomes Program: Leadership and Data Co-ordinating Center (U01 Clinical Trial Optional)"
  (NOT-HL-22-059)
  National Heart, Lung, and Blood Institute
  

• Notice of Pre-Application Webinar for NHLBI SBIR Phase IIB Small Market Awards and Bridge Awards (RFA-HL-23-008 and RFA-HL-23-009)
  (NOT-HL-22-062)
  National Heart, Lung, and Blood Institute
  

• Request for Information (RFI) on Proposed Simplified Review Framework for NIH Research Project Grant Applications
  (NOT-OD-23-034)
  National Institutes of Health
  

Notice of Changes to Funding Opportunities

• Notice of NIAAA's Participation in NOT-DA-22-064 "Notice of Intent to Publish a Funding Opportunity Announcement for NIH Brain Development Cohorts Biospecimen Access (X01 Clinical Trial Not Allowed)"
  (NOT-AA-23-004)
  National Institute on Alcohol Abuse and Alcoholism
  

• Clarification of Number of Applications Allowed Per Institution in RFA-AI-22-067, International Centers of Excellence for Malaria Research (U19 Clinical Trial Not Allowed)
  (NOT-AI-23-005)
  National Institute of Allergy and Infectious Diseases
  

• Notice of Correction to NOT-CA-22-137 for PAR-21-295 NCI Mentored Research Scientist Development Award to Promote Diversity (K01 Independent Clinical Trial Not Allowed)
  (NOT-CA-23-019)
  National Cancer Institute
  

• Notice of Correction to NOT-CA-22-140 for PAR-21-300 NCI Mentored Clinical Scientist Research Career Development Award to Promote Diversity (K08 - Independent Clinical Trial Not Allowed)
  (NOT-CA-23-020)
  National Cancer Institute
  

• Notice of NCIs Participation in RFA-NS-23-006, HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed)
  (NOT-CA-23-021)
  National Cancer Institute
  

• Notice of Clarification for the Funding Opportunity Description in PAR-22-230 "NINR Areas of Emphasis for Research to Optimize Health and Advance Health Equity (R01 Clinical Trial Optional)"
  (NOT-NR-23-006)
  National Institute of Nursing Research
  

• Notice of Clarification for the Funding Opportunity Description in PAR-22-231 "NINR Areas of Emphasis for Research to Optimize Health and Advance Health Equity (R21 Clinical Trial Optional)"
  (NOT-NR-23-007)
  National Institute of Nursing Research
  

• Notice of Change to Eligibility Information for RFA-NS-22-050 "HEAL Initiative: Discovery of Biomarkers and Biomarker Signatures to Facilitate Clinical Trials for Pain Therapeutics (UG3/UH3 Clinical Trial Optional)"
  (NOT-NS-23-051)
  National Institute of Neurological Disorders and Stroke
  

• Notice of NINDS Participation in RFA-TR-22-030: "Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)"
  (NOT-NS-23-052)
  National Institute of Neurological Disorders and Stroke
  National Center for Advancing Translational Sciences
  

Notices of Intent to Publish

• Notice of Intent to Publish a Funding Opportunity Announcement for Reporting Back Environmental Health and Non-Genomic Research Results
  (NOT-ES-23-003)
  National Institute of Environmental Health Sciences
  Office of the Director, NIH
  

Requests for Proposal

• Pre-Solicitation Notice: Cellular Immunology Core Laboratory (CICL), RFP: 75N93022R00029
  (NOT-AI-23-014)
  National Institute of Allergy and Infectious Diseases
  

Notices of Special Interest

• Notice of Special Interest (NOSI): Research to Address Ending the HIV Epidemic Initiative Goals Relevant to Substance Using Populations At-Risk for or Living with HIV
  (NOT-DA-23-013)
  National Institute on Drug Abuse
  

• Notice of Special Interest (NOSI): The Neural Mechanisms of Multi-Dimensional Emotional and Social Representation
  (NOT-MH-23-120)
  National Institute of Mental Health
  

• Notice of Special Interest (NOSI): Research on Gender Measurement (Admin Supp Clinical Trial Optional)
  (NOT-OD-23-029)
  Office of Research on Women's Health
  National Cancer Institute
  National Institute on Aging
  National Institute of Allergy and Infectious Diseases
  National Institute on Drug Abuse
  National Institute on Minority Health and Health Disparities
  National Library of Medicine
  

Funding Opportunities

• Implementation Research on Noncommunicable Disease Risk Factors among Low- and Middle-Income Country and Tribal Populations Living in City Environments (R01 Clinical Trial Optional)
  (PAR-23-042)
  John E. Fogarty International Center
  National Cancer Institute
  National Heart, Lung, and Blood Institute
  National Institute on Aging
  National Institute on Drug Abuse
  National Institute of Environmental Health Sciences
  National Institute of Mental Health
  National Institute on Minority Health and Health Disparities
  National Institute of Neurological Disorders and Stroke
  Office of Disease Prevention
  Application Receipt Date(s): March 09, 2023
  
  

• Implementation Research on Noncommunicable Disease Risk Factors among Low- and Middle-Income Country and Tribal Populations Living in City Environments (R61/R33 Clinical Trial Required)
  (PAR-23-043)
  John E. Fogarty International Center
  National Heart, Lung, and Blood Institute
  National Institute of Mental Health
  Office of Disease Prevention
  Application Receipt Date(s): March 09, 2023
  
  

• NCI Small Grants Program for Cancer Research for Years 2023, 2024, and 2025 (NCI Omnibus) (R03 Clinical Trial Optional)
  (PAR-23-058)
  National Cancer Institute
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Development of Animal Models and Related Biological Materials for Down Syndrome Research (R21 Clinical Trials Not Allowed)
  (PAR-23-067)
  Office of the Director, NIH
  National Institute on Aging
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  Division of Program Coordination, Planning and Strategic Initiatives, Office of Research Infrastructure Programs
  Application Receipt Date(s): January 07, 2026
  
  

• Research Networks to Promote Multidisciplinary Mechanistic Studies on Music-Based Interventions for Pain or Alzheimers Disease and Alzheimers Disease Related Dementias (AD/ADRD) (U24 Clinical Trial Optional)
  (RFA-AT-23-008)
  National Center for Complementary and Integrative Health
  National Institute on Aging
  Application Receipt Date(s): December 15, 2022
  
  

• NIDDK Investigator Award to Support Mentoring of Early Career Researchers from Diverse Backgrounds (K26 - Independent Clinical Trial Not Allowed)
  (RFA-DK-22-012)
  National Institute of Diabetes and Digestive and Kidney Diseases
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• In Vivo Regional Deposition Measurements for Supporting Model Validation (U01) Clinical Trial Required
  (RFA-FD-23-014)
  Food and Drug Administration
  Application Receipt Date(s): March 13, 2023
  
  

• Supporting the use of Real-World Data to Generate Real-World Evidence in Regulatory Decision-Making (U01) Clinical Trials Optional
  (RFA-FD-23-025)
  Food and Drug Administration
  Application Receipt Date(s): February 28, 2023