General Notices

• Notice of Pre-Application Webinar for NOT-AG-23-060, "Notice of Special Interest (NOSI): Telehealth for People and Families Living with Alzheimer's Disease (AD) and AD-Related Dementias (ADRD)"
  (NOT-AG-23-073)
  National Institute on Aging
  

• Notice of Informational Webinar on the NIGMS G-RISE and IMSD Programs
  (NOT-GM-24-016)
  National Institute of General Medical Sciences
  

• Notice of NHLBI Participation in NOT-EY-23-009 "Notice of Special Interest (NOSI): Quantum Sensing in Biomedical Applications (SBIR/STTR)"
  (NOT-HL-23-121)
  National Heart, Lung, and Blood Institute
  

• Notice of Information: NIMH List of Human Genes Having Rare Variants with Strong Statistical Support for Association to Mental Health Traits
  (NOT-MH-24-370)
  National Institute of Mental Health
  

• Technical Assistance Webinars for RFA-NS-24-029 Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)"
  (NOT-NS-24-036)
  National Institute of Neurological Disorders and Stroke
  

• Notice of Correction to the Assistance Listing Number(s) for RFA-OD-23-017 "Tobacco Regulatory Science (R01 Clinical Trial Optional)"
  (NOT-OD-24-030)
  Office of Disease Prevention
  

• Request for Information on Themes for the NIAMS Strategic Plan for Fiscal Years 2025-2029
  (NOT-AR-23-022)
  National Institute of Arthritis and Musculoskeletal and Skin Diseases
  

Notice of Changes to Funding Opportunities

• Notice of Change to Key Dates Listed in RFA-AG-24-030, "Consortium for Economic Research on AD/ADRD Prevention, Treatment, and Care Coordinating Center (U54 Clinical Trial Optional)"
  (NOT-AG-23-074)
  National Institute on Aging
  

• Notice of Change to Key Dates for PAR-23-308, Comprehensive Partnerships to Advance Cancer Health Equity (CPACHE) (U54 Clinical Trial Optional)
  (NOT-CA-24-011)
  National Cancer Institute
  

• Notice of Extension of the Expiration Date for PAR-21-290 "Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional)"
  (NOT-CA-24-012)
  National Cancer Institute
  

• Notice of Correction to Expiration Date for PAR-24-045, "Leveraging Extant Data to Understand Developmental Trajectories of Late Talking Children (R21 Clinical Trial Not Allowed)"
  (NOT-DC-24-008)
  National Institute on Deafness and Other Communication Disorders
  

• Notice of Change: Extension of PAR-22-030 "Translational Efforts to Advance Gene-based Therapies for Ultra-Rare Neurological and Neuromuscular Disorders (U01 - Clinical Trial Optional)" by one Council Round
  (NOT-NS-24-020)
  National Institute of Neurological Disorders and Stroke
  

• Notice of Change: Extension of PAR-22-028 "Ultra-Rare Gene-based Therapy (URGenT) Network Resource Access (X01, Clinical Trial Not Allowed)" by one Council Round
  (NOT-NS-24-035)
  National Institute of Neurological Disorders and Stroke
  

• Notice of Change: Extension of PAR-21-224 "NeuroNEXT Small Business Innovation in Clinical Trials (U44 Clinical Trial Optional)"
  (NOT-NS-24-037)
  National Institute of Neurological Disorders and Stroke
  

Notices of Intent to Publish

• Notice of Intent to Publish a Notice of Funding Opportunity for Open Measurement Coordinating Network for Non-Pharmacological Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) Primary Prevention Trials (U24 Clinical Trial Not Allowed)
  (NOT-AG-23-061)
  National Institute on Aging
  

Notices of Special Interest

• Notice of Special Interest (NOSI): Development and Application of Novel Chemical Approaches to Discover Therapeutic Targets for Substance Use Disorders
  (NOT-DA-25-027)
  National Institute on Drug Abuse
  

• Notice of Special Interest (NOSI): Data Informed, Place-Based Community-Engaged Research to Advance Health Equity
  (NOT-HL-23-110)
  National Heart, Lung, and Blood Institute
  National Cancer Institute
  National Institute of Dental and Craniofacial Research
  National Institute of Environmental Health Sciences
  National Institute of Mental Health
  National Institute on Minority Health and Health Disparities
  National Institute of Nursing Research
  Office of Behavioral and Social Sciences Research
  Office of Disease Prevention
  Office of Research on Women's Health
  

• Notice of Special Interest (NOSI): SBIR/STTR Program Priorities to Bridge Gaps in Advancing the NIMH Mission
  (NOT-MH-24-110)
  National Institute of Mental Health
  

• Notice of Special Interest (NOSI): SBIR/STTR High-Priority Areas for Digital Mental Health Innovations
  (NOT-MH-24-120)
  National Institute of Mental Health
  

Funding Opportunities

• NINDS Exploratory Clinical Trials for Small Business (R43/R44 Clinical Trial Required)
  (PAR-23-311)
  National Institute of Neurological Disorders and Stroke
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Native American Research Centers for Health (NARCH) Planning Grants (R34 - Clinical Trial Not Allowed)
  (PAR-24-041)
  National Institute of General Medical Sciences
  Application Receipt Date(s): July 08, 2026
  
  

• NINDS Exploratory Clinical Trials for Small Business (R41/R42 Clinical Trial Required)
  (PAR-24-044)
  National Institute of Neurological Disorders and Stroke
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Providing Research Education Experiences to Enhance Inclusivity for a Diverse Substance Use and Addiction Scientific Workforce (R25 Clinical Trials Not Allowed)
  (PAR-24-048)
  National Institute on Drug Abuse
  National Institute on Alcohol Abuse and Alcoholism
  Application Receipt Date(s): November 13, 2026
  
  

• NEI Small Business Innovation Research (SBIR) Cooperative Agreement for Early-Stage Clinical Trials with Greater than Minimal Risk (U44-Clinical Trial Required)
  (PAR-24-066)
  National Eye Institute
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Alcohol Research-Related Resource Award (R24 Clinical Trial Not Allowed)
  (PAR-24-071)
  National Institute on Alcohol Abuse and Alcoholism
  Application Receipt Date(s): September 25, 2026
  
  

• Addressing Health and Health Care Disparities among Sexual and Gender Minority Populations (R01 - Clinical Trials Optional)
  (PAR-24-077)
  National Institute on Minority Health and Health Disparities
  National Center for Complementary and Integrative Health
  National Cancer Institute
  National Institute on Alcohol Abuse and Alcoholism
  National Institute on Drug Abuse
  National Institute of Mental Health
  Office of Behavioral and Social Sciences Research
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Resources to Promote Coordination and Collaboration across Deeply Phenotyped Longitudinal Behavioral and Social Studies of Aging (U24 Clinical Trial Not Allowed)
  (RFA-AG-25-006)
  National Institute on Aging
  Application Receipt Date(s): February 14, 2024
  
  

• Innovative Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)
  (RFA-CA-24-008)
  National Cancer Institute
  Application Receipt Date(s): October 01, 2024
  
  

• Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)
  (RFA-CA-24-009)
  National Cancer Institute
  Application Receipt Date(s): October 01, 2024
  
  

• Innovative Biospecimen Science Technologies for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)
  (RFA-CA-24-010)
  National Cancer Institute
  Application Receipt Date(s): October 01, 2024
  
  

• Advanced Development and Validation of Emerging Biospecimen Science Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)
  (RFA-CA-24-011)
  National Cancer Institute
  Application Receipt Date(s): October 01, 2024
  
  

• Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (R01 Clinical Trial Optional)
  (RFA-CA-24-012)
  National Cancer Institute
  Application Receipt Date(s): October 01, 2024
  
  

• Revision Applications for Incorporation of Novel NCI- Supported Technology to Accelerate Cancer Research (U01 Clinical Trial Optional)
  (RFA-CA-24-013)
  National Cancer Institute
  Application Receipt Date(s): October 01, 2024
  
  

• Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (P50 Clinical Trial Optional)
  (RFA-CA-24-014)
  National Cancer Institute
  Application Receipt Date(s): October 01, 2024
  
  

• Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (P30 Clinical Trial Optional)
  (RFA-CA-24-015)
  National Cancer Institute
  Application Receipt Date(s): October 01, 2024
  
  

• BRAIN Initiative: Brain-Behavior Quantification and Synchronization Transformative and Integrative Models of Behavior at the Organismal Level (R34 Clinical Trial Optional)
  (RFA-DA-24-042)
  National Institute on Drug Abuse
  National Center for Complementary and Integrative Health
  National Eye Institute
  National Institute on Aging
  National Institute on Alcohol Abuse and Alcoholism
  National Institute of Biomedical Imaging and Bioengineering
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute on Deafness and Other Communication Disorders
  National Institute of Mental Health
  National Institute of Neurological Disorders and Stroke
  Office of Behavioral and Social Sciences Research
  Application Receipt Date(s): February 15, 2024
  
  

• Cardiovascular Repository Type 1 Diabetes (CARE-T1D) Consortium (U01 Clinical Trial Not Allowed).
  (RFA-DK-23-021)
  National Institute of Diabetes and Digestive and Kidney Diseases
  National Heart, Lung, and Blood Institute
  Application Receipt Date(s): April 11, 2024
  
  

• Addressing the Impact of Syndemics on the Health of People with HIV and Diseases and Conditions within the Missions of NIDDK and NHLBI (R01 Clinical Trial Optional)
  (RFA-DK-25-001)
  National Institute of Diabetes and Digestive and Kidney Diseases
  National Heart, Lung, and Blood Institute
  Office of Research on Women's Health
  Application Receipt Date(s): March 20, 2025
  
  

• Utilizing Real-World Data and Algorithmic Analyses to Assess Post-Market Clinical Outcomes in Patients Switching Amongst Therapeutically Equivalent Complex Generic Drug Products and Reference Listed Drugs (U01) Clinical Trial Not Allowed
  (RFA-FD-24-007)
  Food and Drug Administration
  Application Receipt Date(s): March 31, 2024
  
  

• Short-Term Research Education Program to Enhance Diversity in Health-Related Research (R25 Clinical Trial Not Allowed)
  (RFA-HL-25-001)
  National Heart, Lung, and Blood Institute
  Application Receipt Date(s): August 19, 2026
  
  

• Early Psychosis Intervention Network (EPINET): Learning Health Care Research to Improve Mental Health Services and Outcomes (P01 Clinical Trial Optional)
  (RFA-MH-24-105)
  National Institute of Mental Health
  Application Receipt Date(s): March 29, 2024
  
  

• Early Psychosis Intervention Network (EPINET) Data Coordinating Center (U24 Clinical Trial Not Allowed)
  (RFA-MH-24-106)
  National Institute of Mental Health
  Application Receipt Date(s): March 29, 2024
  
  

• BRAIN Initiative: Marmoset Colonies for Neuroscience Research (U24 Clinical Trials Not Allowed)
  (RFA-MH-25-115)
  National Institute of Mental Health
  National Center for Complementary and Integrative Health
  National Eye Institute
  National Institute on Aging
  National Institute on Alcohol Abuse and Alcoholism
  National Institute of Biomedical Imaging and Bioengineering
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute on Drug Abuse
  National Institute on Deafness and Other Communication Disorders
  National Institute of Dental and Craniofacial Research
  National Institute of Environmental Health Sciences
  National Institute of Neurological Disorders and Stroke
  Office of Behavioral and Social Sciences Research
  Application Receipt Date(s): March 01, 2024
  
  

• BRAIN Initiative: Marmoset Coordination Center (U24 Clinical Trials Not Allowed)
  (RFA-MH-25-116)
  National Institute of Mental Health
  National Center for Complementary and Integrative Health
  National Eye Institute
  National Institute on Aging
  National Institute on Alcohol Abuse and Alcoholism
  National Institute of Biomedical Imaging and Bioengineering
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute on Drug Abuse
  National Institute on Deafness and Other Communication Disorders
  National Institute of Dental and Craniofacial Research
  National Institute of Environmental Health Sciences
  National Institute of Neurological Disorders and Stroke
  Office of Behavioral and Social Sciences Research
  Application Receipt Date(s): March 01, 2024
  
  

• Short Courses to Promote the Broad and Rigorous Use of Common Fund Data (R25 Clinical Trial Not Allowed)
  (RFA-RM-23-014)
  Office of Strategic Coordination (Common Fund)
  Application Receipt Date(s): February 14, 2024
  
  

• Basket Clinical Trials of Drugs Targeting Shared Molecular Etiologies in Multiple Rare Diseases (U44 Clinical Trial Required)
  (RFA-TR-24-001)
  National Center for Advancing Translational Sciences
  Application Receipt Date(s): March 15, 2024