Policy Notices

• eRA Retirement of All Application Form Versions Prior to FORMS-E
  (NOT-OD-22-182)
  National Institutes of Health
  Agency for Healthcare Research and Quality
  Food and Drug Administration
  

General Notices

• Notice of Technical Assistance Webinar for NHLBI New Epidemiological Cohort Study among Asian Americans, Native Hawaiians, and Pacific Islanders (AsA-NHPI) Clinical/Community Field Centers (UG3/UH3) RFA-HL-23-015 and Coordinating Center (U24) RFA-HL-23-016
  (NOT-HL-22-034)
  National Heart, Lung, and Blood Institute
  

• Notice of Change to Language for the Eligible Individual Criteria for PA-21-052: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31-Diversity)
  (NOT-OD-22-183)
  Office of the Director, NIH
  

• Register Today for the NIH Data Management and Sharing (DMS) Policy Webinar Series
  (NOT-OD-22-184)
  Office of the Director, NIH
  

• Notice Announcing NIH All of Us Research Program Engagement, Communications, and Enrollment Partners Other Transactions (OT) Research Opportunity Announcement (ROA)
  (NOT-PM-22-003)
  Office of the Director, NIH
  

• Request for Information: Medical Rehabilitation Research Infrastructure Support
  (NOT-HD-22-029)
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  

Notice of Changes to Funding Opportunities

• Notice of Change to NOT-AA-20-018 "Notice of Special Interest: Secondary Analyses of Existing Alcohol Research Data"
  (NOT-AA-22-014)
  National Institute on Alcohol Abuse and Alcoholism
  

• Notice of Participation and Areas of Interest of NIMH in RFA-HL-23-015 and RFA-HL-23-016 "New Epidemiological Cohort Study among Asian Americans, Native Hawaiians, and Pacific Islanders (AsA-NHPI) (UG3/UH3) (U24)"
  (NOT-MH-22-175)
  National Institute of Mental Health
  

• Notice of Early Expiration of NOT-OD-22-106 Notice of Special Interest (NOSI): Increasing Uptake of Evidence-Based Screening in Diverse Populations Across the Lifespan
  (NOT-OD-22-176)
  Office of Disease Prevention
  

• Notice of Early Expiration of NOT-OD-22-107 Notice of Special Interest (NOSI): Addressing Evidence Gaps in Screening
  (NOT-OD-22-177)
  Office of Disease Prevention
  

Notices of Intent to Publish

• Notice of Intent to Publish a Funding Opportunity Announcement: An Open-Access Repository and Database for Anatomical and Physiological Ontology of Acupoints (U24 Clinical Trial Optional)
  (NOT-AT-23-002)
  National Center for Complementary and Integrative Health
  

• Notice of Intent to Publish a Funding Opportunity Announcement for NCI Pathway to Independence Award for Outstanding Early Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Not Allowed)
  (NOT-CA-22-096)
  National Cancer Institute
  

• Notice of Intent to Publish a Funding Opportunity Announcement for NCI Pathway to Independence Award for Outstanding Early Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Required)
  (NOT-CA-22-097)
  National Cancer Institute
  

• Notice of Intent to Publish a Funding Opportunity Announcement for NCI Pathway to Independence Award for Outstanding Early Stage Postdoctoral Researchers (K99/R00 - Independent Basic Experimental Studies with Humans Required)
  (NOT-CA-22-098)
  National Cancer Institute
  

• Notice of Intent to Publish a Funding Opportunity Announcement for Bioengineering Research Grants (BRG) (R01 Clinical Trial Not Allowed)
  (NOT-CA-22-110)
  National Cancer Institute
  National Institute of Neurological Disorders and Stroke
  

• Notice of Intent to Publish a Funding Opportunity Announcement for Bioengineering Research Grants (BRG) (R01 Clinical Trial Required)
  (NOT-CA-22-111)
  National Cancer Institute
  National Institute of Neurological Disorders and Stroke
  

• Notice of Intent to Publish a Funding Opportunity Announcement for Radiation Oncology-Biology Integration Network (ROBIN) Centers (U54 Clinical Trial Required)
  (NOT-CA-22-113)
  National Cancer Institute
  

• Notice of Intent to Publish a Funding Opportunity Announcement for HEAL Initiative: Prevention and Management of Chronic Pain in Rural Populations (UG3/UH3, Clinical Trials Required)
  (NOT-NR-22-015)
  National Institute of Nursing Research
  National Center for Complementary and Integrative Health
  National Cancer Institute
  National Heart, Lung, and Blood Institute
  National Institute on Aging
  National Institute on Alcohol Abuse and Alcoholism
  National Institute on Drug Abuse
  National Institute of Dental and Craniofacial Research
  National Institute on Minority Health and Health Disparities
  National Institute of Neurological Disorders and Stroke
  

• Notice of Intent to Publish a Funding Opportunity Announcement for Limited Competition for the Continuation of Clinical Sites for the Undiagnosed Diseases Network (U01 - Clinical Trial Not Allowed)
  (NOT-NS-23-008)
  National Institute of Neurological Disorders and Stroke
  National Human Genome Research Institute
  

• Notice of Intent to Publish a Funding Opportunity Announcement for Advanced Training in Artificial Intelligence for Precision Nutrition Science Research (AIPrN) Institutional Research Training Programs (T32)
  (NOT-OD-22-168)
  Office of Nutrition Research
  National Center for Complementary and Integrative Health
  National Cancer Institute
  National Heart, Lung, and Blood Institute
  National Institute on Aging
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute of Dental and Craniofacial Research
  National Institute of Diabetes and Digestive and Kidney Diseases
  National Institute of Neurological Disorders and Stroke
  

Notices of Special Interest

• Notice of Special Interest (NOSI): HEAL Initiative: Regarding the Availability of Administrative Supplements to Support the Addition of Justice Measures
  (NOT-DA-23-011)
  National Institute on Drug Abuse
  National Center for Complementary and Integrative Health
  National Institute of Arthritis and Musculoskeletal and Skin Diseases
  

• Notice of Special Interest (NOSI): Program Priority Areas for MOSAIC UE5 - November 2022 Application Due Date
  (NOT-GM-22-038)
  National Institute of General Medical Sciences
  

• Notice of Special Interest (NOSI): Research on the Health of Sexual and Gender Minority (SGM) Populations
  (NOT-MD-22-012)
  National Institute on Minority Health and Health Disparities
  National Center for Complementary and Integrative Health
  National Cancer Institute
  National Human Genome Research Institute
  National Institute on Aging
  National Institute of Allergy and Infectious Diseases
  National Institute of Arthritis and Musculoskeletal and Skin Diseases
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute on Drug Abuse
  National Institute on Deafness and Other Communication Disorders
  National Institute of Dental and Craniofacial Research
  National Institute of Diabetes and Digestive and Kidney Diseases
  National Institute of Environmental Health Sciences
  National Institute of Neurological Disorders and Stroke
  National Institute of Nursing Research
  Office of Disease Prevention
  Office of Research on Women's Health
  

• HEAL Initiative Notice of Special Interest (NOSI): Development and Validation of Pain-Related Models and Endpoints to Facilitate Non-Addictive Analgesic Discovery
  (NOT-NS-22-095)
  National Institute of Neurological Disorders and Stroke
  National Center for Complementary and Integrative Health
  National Cancer Institute
  National Eye Institute
  National Institute on Aging
  National Institute on Alcohol Abuse and Alcoholism
  National Institute of Arthritis and Musculoskeletal and Skin Diseases
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute of Dental and Craniofacial Research
  National Institute of Diabetes and Digestive and Kidney Diseases
  

• Notice of Special Interest (NOSI): Increasing Uptake of Evidence-Based Screening in Diverse Populations Across the Lifespan
  (NOT-OD-22-178)
  Office of Disease Prevention
  National Cancer Institute
  National Institute on Aging
  National Institute on Alcohol Abuse and Alcoholism
  National Institute of Arthritis and Musculoskeletal and Skin Diseases
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute on Drug Abuse
  National Institute on Deafness and Other Communication Disorders
  National Institute of Dental and Craniofacial Research
  National Institute of Mental Health
  National Institute on Minority Health and Health Disparities
  National Institute of Neurological Disorders and Stroke
  National Institute of Nursing Research
  Office of Dietary Supplements
  Office of Research on Women's Health
  

• Notice of Special Interest (NOSI): Addressing Evidence Gaps in Screening
  (NOT-OD-22-179)
  Office of Disease Prevention
  National Institute on Aging
  National Institute on Alcohol Abuse and Alcoholism
  National Institute of Arthritis and Musculoskeletal and Skin Diseases
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute on Drug Abuse
  National Institute on Deafness and Other Communication Disorders
  National Institute of Dental and Craniofacial Research
  National Institute of Mental Health
  National Institute on Minority Health and Health Disparities
  National Institute of Neurological Disorders and Stroke
  National Institute of Nursing Research
  Office of Dietary Supplements
  Office of Research on Women's Health
  

• Notice of Special Interest: Administrative Supplement to Building Interdisciplinary Research Careers in Womens Health (BIRCWH)
  (NOT-OD-22-180)
  Office of Research on Women's Health
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute on Drug Abuse
  

Funding Opportunities

• Single-Site Investigator-Initiated Clinical Trials (R61/R33 Clinical Trial Required)
  (PAR-22-189)
  National Heart, Lung, and Blood Institute
  Application Receipt Date(s): September 11, 2025
  
  

• Modern Equipment for Shared-use Biomedical Research Facilities: Advancing Research-Related Operations (R24 Clinical Trials Not Allowed)
  (PAR-22-190)
  Division of Program Coordination, Planning and Strategic Initiatives, Office of Research Infrastructure Programs
  National Institute of General Medical Sciences
  Application Receipt Date(s): November 07, 2022
  
  

• Postdoctoral Research Associate Training (PRAT) Program (Fi2)
  (PAR-22-191)
  National Institute of General Medical Sciences
  Application Receipt Date(s): October 03, 2024
  
  

• Clinical Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)
  (PAR-22-192)
  National Heart, Lung, and Blood Institute
  Application Receipt Date(s): September 11, 2025
  
  

• Data Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative U24 Clinical Trial Required)
  (PAR-22-193)
  National Heart, Lung, and Blood Institute
  Application Receipt Date(s): September 11, 2025
  
  

• Point-of-Care Technologies Research Network: Technology Research and Development Centers (TRDC) (U54 Clinical Trial Optional)
  (PAR-22-203)
  National Institute of Biomedical Imaging and Bioengineering
  John E. Fogarty International Center
  National Center for Complementary and Integrative Health
  National Cancer Institute
  National Heart, Lung, and Blood Institute
  National Institute of Allergy and Infectious Diseases
  National Institute on Drug Abuse
  Application Receipt Date(s): January 07, 2023
  
  

• Research to Action: Assessing and Addressing Community Exposures to Environmental Contaminants (R01 Clinical Trial Optional)
  (PAR-22-210)
  National Institute of Environmental Health Sciences
  National Institute on Minority Health and Health Disparities
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Institutional Research and Academic Career Development Awards (IRACDA) (K12 - Independent Clinical Trial Not Allowed)
  (PAR-22-212)
  National Institute of General Medical Sciences
  Application Receipt Date(s): October 03, 2024
  
  

• NCI Clinical and Translational Exploratory/Developmental Studies (R21 Clinical Trial Optional)
  (PAR-22-216)
  National Cancer Institute
  Application Receipt Date(s): July 01, 2025
  
  

• HEAL Initiative: Career Development Awards in Implementation Science for Substance Use Prevention and Treatment (K01 - Clinical Trial Required)
  (PAS-22-206)
  National Institute on Drug Abuse
  National Center for Complementary and Integrative Health
  National Cancer Institute
  National Institute on Alcohol Abuse and Alcoholism
  National Institute of Mental Health
  Application Receipt Date(s): November 12, 2025
  
  

• HEAL Initiative: Career Development Awards in Implementation Science for Substance Use Prevention and Treatment (K23 - Clinical Trial Required)
  (PAS-22-207)
  National Institute on Drug Abuse
  National Center for Complementary and Integrative Health
  National Cancer Institute
  National Institute on Alcohol Abuse and Alcoholism
  National Institute of Mental Health
  Application Receipt Date(s): November 12, 2025
  
  

• More Monitoring of Cognitive Change, Continued (M3C3) (U2C Clinical Trial Optional)
  (RFA-AG-23-021)
  National Institute on Aging
  Application Receipt Date(s): October 20, 2022
  
  

• HEAL Initiative: Pragmatic and Implementation Studies for the Management of Sickle Cell Disease Pain (UG3/UH3, Clinical Trials Optional)
  (RFA-AT-23-001)
  National Center for Complementary and Integrative Health
  National Eye Institute
  National Heart, Lung, and Blood Institute
  National Institute of Arthritis and Musculoskeletal and Skin Diseases
  National Institute on Minority Health and Health Disparities
  National Institute of Nursing Research
  Office of Behavioral and Social Sciences Research
  Office of Research on Women's Health
  Application Receipt Date(s): November 21, 2022
  
  

• HEAL Initiative: Sickle Cell Disease Pain Management Trials Utilizing the Pain Management Effectiveness Research Network Cooperative Agreement (UG3/UH3, Clinical Trial Required)
  (RFA-AT-23-002)
  National Center for Complementary and Integrative Health
  National Center for Advancing Translational Sciences
  National Eye Institute
  National Heart, Lung, and Blood Institute
  National Institute of Arthritis and Musculoskeletal and Skin Diseases
  National Institute on Minority Health and Health Disparities
  National Institute of Nursing Research
  Office of Research on Women's Health
  Application Receipt Date(s): November 21, 2022
  
  

• Limited Competition: Cancer Immune Monitoring and Analysis Centers (CIMACs) and Cancer Immunologic Data Center (CIDC) (U24 Clinical Trial Not Allowed)
  (RFA-CA-22-038)
  National Cancer Institute
  Application Receipt Date(s): Not Applicable
  
  

• HEAL Initiative: Multilevel Interventions to Reduce Harm and Improve Quality of Life for Patients on Long Term Opioid Therapy (MIRHIQL) (R01 Clinical Trial Required)
  (RFA-DA-23-041)
  National Institute on Drug Abuse
  National Center for Complementary and Integrative Health
  National Cancer Institute
  National Institute on Aging
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute of Mental Health
  Application Receipt Date(s): September 27, 2022
  
  

• HEAL Initiative: Multilevel Interventions to Reduce Harm and Improve Quality of Life for Patients on Long Term Opioid Therapy (MIRHIQL): Resource Center (U24- Clinical Trial Optional)
  (RFA-DA-23-042)
  National Institute on Drug Abuse
  National Center for Complementary and Integrative Health
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  Application Receipt Date(s): September 27, 2022
  
  

• HEAL Initiative: Preventing Opioid Misuse and Co-Occurring Conditions by Intervening on Social Determinants (R01 - Clinical Trials Optional)
  (RFA-DA-23-051)
  National Institute on Drug Abuse
  National Center for Complementary and Integrative Health
  National Cancer Institute
  National Institute on Aging
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute of Mental Health
  Office of Disease Prevention
  Application Receipt Date(s): February 02, 2023
  
  

• Mass Spectrometric Assays for the Reliable and Reproducible Detection of Proteins/Peptides of Importance in Type 1 Diabetes (T1D) Research (U01 Clinical Trial Not Allowed)
  (RFA-DK-21-031)
  National Institute of Diabetes and Digestive and Kidney Diseases
  Application Receipt Date(s): October 26, 2022
  
  

• Human Islet Research Network - Consortium on Targeting and Regeneration (HIRN-CTAR) (U01 Clinical Trial Not Allowed)
  (RFA-DK-22-009)
  National Institute of Diabetes and Digestive and Kidney Diseases
  Application Receipt Date(s): October 26, 2022
  
  

• Chronic Kidney Disease in Children Central Biochemistry Laboratory (U24 Clinical Trial Not Allowed)
  (RFA-DK-22-010)
  National Institute of Diabetes and Digestive and Kidney Diseases
  National Heart, Lung, and Blood Institute
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  Application Receipt Date(s): October 26, 2022
  
  

• Understanding the Pathophysiology and Clinical Course of New-Onset Diabetes Following COVID-19 (U01 Clinical Trial Not Allowed)
  (RFA-DK-22-016)
  National Institute of Diabetes and Digestive and Kidney Diseases
  Application Receipt Date(s): December 20, 2022
  
  

• Collaborative Research Using Biosamples from Type 1 Diabetes Clinical Studies (R01 - Clinical Trial Not Allowed)
  (RFA-DK-22-021)
  National Institute of Diabetes and Digestive and Kidney Diseases
  Application Receipt Date(s): October 26, 2023
  
  

• Limited Competition for Continuation of the Prospective Study of Chronic Kidney Disease in Children Clinical Coordinating Centers (U01 Clinical Trial Not Allowed)
  (RFA-DK-22-504)
  National Institute of Diabetes and Digestive and Kidney Diseases
  National Heart, Lung, and Blood Institute
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  Application Receipt Date(s): Not Applicable
  
  

• Limited Competition for Continuation of the Prospective Study of Chronic Kidney Disease in Children Data Coordinating Center (U24 Clinical Trial Not Allowed)
  (RFA-DK-22-505)
  National Institute of Diabetes and Digestive and Kidney Diseases
  National Heart, Lung, and Blood Institute
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  Application Receipt Date(s): Not Applicable
  
  

• BRAIN Initiative: Transformative Brain Non-invasive Imaging Technology Development (UG3/UH3 Clinical Trial Not Allowed)
  (RFA-EB-22-001)
  National Institute of Biomedical Imaging and Bioengineering
  National Center for Complementary and Integrative Health
  National Eye Institute
  National Institute on Aging
  National Institute on Alcohol Abuse and Alcoholism
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute on Drug Abuse
  National Institute on Deafness and Other Communication Disorders
  National Institute of Mental Health
  National Institute of Neurological Disorders and Stroke
  Application Receipt Date(s): Multiple dates, see announcement.
  
  

• Epigenetic Mechanisms Regulating HIV CNS Latency and Neuropathogenesis Using Novel Single Cell Technologies (R01 Clinical Trial Not Allowed)
  (RFA-MH-22-280)
  National Institute of Mental Health
  National Institute of Neurological Disorders and Stroke
  Application Receipt Date(s): December 05, 2022
  
  

• Epigenetic Mechanisms Regulating HIV CNS Latency and Neuropathogenesis Using Novel Single Cell Technologies (R21 Clinical Trial Not Allowed)
  (RFA-MH-22-281)
  National Institute of Mental Health
  National Institute of Neurological Disorders and Stroke
  Application Receipt Date(s): December 05, 2022
  
  

• Galvanizing Health Equity Through Novel and Diverse Educational Resources (GENDER) Research Education R25 (R25 Clinical Trial Not Allowed)
  (RFA-OD-22-015)
  Office of Research on Women's Health
  National Institute on Aging
  National Institute of Arthritis and Musculoskeletal and Skin Diseases
  Eunice Kennedy Shriver National Institute of Child Health and Human Development
  National Institute on Drug Abuse
  National Institute of Dental and Craniofacial Research
  National Institute on Minority Health and Health Disparities
  National Library of Medicine
  Office of AIDS Research
  Office of Behavioral and Social Sciences Research
  Application Receipt Date(s): January 07, 2023
  
  

• Basket Clinical Trials of Drugs Targeting Shared Molecular Etiologies in Multiple Rare Diseases (U44 Clinical Trial Required)
  (RFA-TR-22-029)
  National Center for Advancing Translational Sciences
  Application Receipt Date(s): July 12, 2023