PA-23-231 - PHS 2023-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required) is used for the submission of applications to the following Notices of Special Interest (NOSIs)

Expired NOSIs

Title Notice Number Organization Release Date Expiration Date Activity Code(s)
Notice of Special Interest (NOSI): Improving Adherence to Treatment and Prevention Regimens and Maintenance of Health Behaviors to Promote Health NOT-OD-24-146 OBSSR, NCCIH, NCI, NEI, NHLBI, NIA, NIDA, NIMH, NIMHD, NINR, OAR, ODP, ORWH Jun 24, 2024 Sep 9, 2025 P01, P30, R01, R03, UG3/UH3, R34, U24, R41/R42, R21, R43/R44, R21/R33, R61
Notice of Special Interest (NOSI): Translating Biomaterials-Based Technologies to Commercially Viable Products NOT-EB-24-001 NIBIB, NCATS, NCCIH, NHLBI, NIDCR Mar 29, 2024 Sep 9, 2025 R41/R42, R43/R44
Notice of Special Interest: Womens Health Research NOT-OD-24-079 ORWH, FIC, NCATS, NCCIH, NCI, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDA, NIDCD, NIDCR, NIDDK, NIEHS, NIGMS, NIMH, NIMHD, NINDS, NINR, NLM, OAR, OBSSR, ODP, ODS, ODSS Mar 26, 2024 Sep 9, 2025 R15, R01, K01, R16, K08, R21, K43, F31, R43/R44, R41/R42, F30, R03, K23, F32, R34
Notice of Special Interest (NOSI): Development of Imaging Techniques for High Resolution and Functional Scanning of In Vivo Human Sensory and Communication Systems NOT-DC-24-025 NIDCD Mar 22, 2024 Sep 9, 2025 R01, U01, R43/R44, R41/R42, R21
Notice of Special Interest (NOSI): Validation of Digital Health and Artificial Intelligence/Machine Learning Tools for Improved Assessment in Biomedical and Behavioral Research NOT-CA-24-031 NCI, NHLBI, NIA, NIDA, NIMH, NINR, OBSSR, ODSS Feb 15, 2024 Jul 6, 2025 R61/R33, R01, R21, R43/R44, R34, R41/R42
Notice of Special Interest (NOSI): Innovative Technologies for Research on Climate Change and Human Health NOT-ES-24-002 NIEHS, NCATS, NCCIH, NEI, NHLBI, NIA, NIAID, NIAMS, NLM Feb 15, 2024 Apr 6, 2025 R43/R44, R41/R42
Notice of Special Interest (NOSI): Advancing Genomic Medicine Research through Small Businesses NOT-HG-24-016 NHGRI Feb 14, 2024 Sep 9, 2025 R43/R44, R41/R42
Notice of Special Interest (NOSI): SBIR/STTR High-Priority Areas for Digital Mental Health Innovations NOT-MH-24-120 NIMH Nov 29, 2023 Sep 9, 2025 R41/R42, R43/R44
Notice of Special Interest (NOSI): SBIR/STTR Program Priorities to Bridge Gaps in Advancing the NIMH Mission NOT-MH-24-110 NIMH Nov 29, 2023 Sep 9, 2025 R43/R44, R41/R42
Notice of Special Interest: Encouraging Small Businesses to Partner with Resource-Limited Institutions (RLIs) on Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Program Applications NOT-OD-23-179 OD Oct 3, 2023 Apr 6, 2024 R43/R44, R41/R42
Notice of Special Interest (NOSI): The Road to Prevention of Stillbirth NOT-HD-23-021 NICHD Oct 3, 2023 Sep 9, 2025 F31, R03, R15, K08, R01, R21, F30, U24, R43/R44, K23, R41/R42, R25, S06, F32, U01
Notice of Special Interest (NOSI): Quantum Sensing in Biomedical Applications (SBIR/STRR) NOT-EY-23-009 NEI, NCATS, NCI Sep 6, 2023 Sep 6, 2024 R43/R44, R41/R42
Notice of Special Interest (NOSI): Small Business Initiatives for Innovative tools and Technologies for Improving Outcomes for Maternal Health NOT-EB-23-005 NIBIB, NCATS, NHLBI, NIAMS, NIMH, NIMHD, NINDS, ORWH Jul 26, 2023 Sep 9, 2025 U44, R43/R44, R41/R42
Notice of Special Interest (NOSI): Innovative Technologies to develop novel tools to prevent and treat HIV in underserved populations NOT-MH-23-200 NIMH Jul 18, 2023 Sep 9, 2025 R41/R42, R43/R44
Notice of Special Interest (NOSI): Developmentally Tailored HIV Prevention and Care Research for Adolescents and Young Adults NOT-MH-23-250 NIMH May 19, 2023 Sep 9, 2025 K43, R41/R42, R21, K08, R25, K99/R00, T32, K01, F30, R34, R03, F31, R15, R43/R44, K24, K23, F32, R01
Notice of Special Interest (NOSI): Promoting Language and Communication in Minimally Verbal/Non-Speaking Individuals with Autism NOT-DC-23-009 NIDCD Apr 3, 2023 Sep 9, 2025 R13, R15, R01, U01, R21, R43/R44, R41/R42, R03
Notice of Special Interest (NOSI): Small Business Digital Technologies for Early Detection, Characterization and Monitoring of Senescence-Related Changes NOT-AG-23-004 NIA Feb 7, 2023 Sep 9, 2025 R43/R44, R41/R42
Notice of Special Interest (NOSI): Development of Functional Assay Sites to Evaluate Candidate -Omics Variants Associated with Heart, Lung, Blood, or Sleep Disease (R01, R41, R42, R43, R44) NOT-HL-23-066 NHLBI Jan 31, 2023 Sep 9, 2025 R41/R42, R43/R44, R01
Notice of Special Interest (NOSI): Advancing Research Needed to Develop a Coccidioidomycosis (Valley fever) Vaccine NOT-AI-23-007 NIAID Nov 25, 2022 Sep 9, 2025 R21, R41/R42, R43/R44, R01
Notice of Special Interest (NOSI): Technological Innovations for Advancing Clinical SPECT Imaging NOT-EB-22-006 NIBIB Mar 21, 2022 May 8, 2024 R21, F30, K01, R13, K23, K25, R43/R44, K08, R01, K99/R00, R41/R42, F32, R03, F31
Notice of Special Interest (NOSI): Research Addressing Eye and Vision Health Equity/Health Disparities NOT-EY-22-004 NEI, NIMHD Feb 14, 2022 Jan 25, 2025 R01, UG1, F31, R21, 333, K99/R00, K08, F30, K23, R43/R44, R34, R41/R42, F32
Notice of Special Interest (NOSI): Addressing Accessibility Inequities with COVID Home-Based Testing for Individuals with Visual Impairment NOT-EY-22-010 NEI Feb 4, 2022 Mar 9, 2024 R41/R42, R15, 333, R01, R43/R44, R21
Notice of Special Interest (NOSI): Validation of Digital Health and Artificial Intelligence Tools for Improved Assessment in Epidemiological, Clinical, and Intervention Research NOT-CA-22-037 NCI, NHLBI, NIA, NIDA, NIMH, NINR, OBSSR Jan 27, 2022 Mar 9, 2024 R01, R03, R21, R43/R44, R41/R42, R33, R34, R61/R33
Notice of Special Interest (NOSI): Advancing Innovative Non-invasive Physiologic Monitoring To Improve Fetal Assessment NOT-HD-21-053 NICHD Dec 28, 2021 May 8, 2024 R03, R01, R41/R42, R43/R44, R21
Notice of Special Interest: Research on Pain, Pain Management, and Opioids in Aging NOT-AG-22-004 NIA Dec 22, 2021 Jan 8, 2025 F31, P01, K99/R00, K08, R01, K01, R43/R44, F32, 332, F33, F99/K00, R15, K24, R21, K02, K25, R25, F30, K23, R36, R41/R42, SB1, K76, K22, K07, R13, R21/R33, U19
Notice of Special Interest (NOSI): Epidemiology and Prevention of Alcohol Misuse in Understudied Young Adult Populations; Military, Workforce, and Community College NOT-AA-22-001 NIAAA Dec 9, 2021 Sep 9, 2025 R21, R03, R01, R43/R44, R41/R42
Notice of Special Interest (NOSI): National Cancer Institute SBIR/STTR Program Announcement Regarding Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings NOT-CA-21-062 NCI Jul 23, 2021 Sep 7, 2024 R43/R44, R41/R42
Notice of Special Interest (NOSI): Navigating Pediatric to Adult Health Care: Lost in Transition NOT-HD-21-027 NICHD, NIAAA, NCI, NIMH, NIAMS, OBSSR, NIBIB, NIDCR Jun 22, 2021 Jan 8, 2024 R01, R21, R43/R44, R41/R42
Notice of Special Interest: NIDCD Health Disparities and Inequities Research NOT-DC-21-003 NIDCD, SGMRO Jun 11, 2021 May 8, 2024 R01, R21, P50, F30, F31, F32, F99/K00, K01, K08, K18, K23, K24, K25, K99/R00, 333, R41/R42, R43/R44
Notice of Special Interest (NOSI): Improving Patient Adherence to Treatment and Prevention Regimens to Promote Health NOT-OD-21-100 OBSSR, NIMHD, NIDA, NIMH, ORWH, NIDCD, SGMRO, ODP, NIA, NHLBI, NCI, NINR, NCCIH, NEI, NICHD Apr 8, 2021 Jun 8, 2024 R01, R21, R03, R41/R42, R43/R44, R21/R33, UG3/UH3, R34
Notice of Special Interest (NOSI): Hearing Healthcare for Adults: Improving Access and Affordability NOT-DC-21-001 NIDCD Feb 16, 2021 Jan 8, 2024 R01, R21, U01, R43/R44, R41/R42
Notice of Special Interest (NOSI): Understanding the effects of cancer and cancer treatment on aging trajectories and aging outcomes NOT-CA-21-031 NCI, NIA Jan 27, 2021 Jan 8, 2024 R21, R03, R01, U01, P01, K99/R00, K08, R43/R44, R41/R42, R13, R21/R33, K01, K23
Notice of Special Interest: Kidney Precision Medicine Technology Development and Translation NOT-DK-21-007 NIDDK Dec 2, 2020 Sep 6, 2023 R43/R44, R41/R42
Notice of Special Interest (NOSI): Development and/or Validation of Devices or Electronic Systems to Monitor or Enhance Mind and Body Interventions (SBIR/STTR) NOT-AT-21-001 NCCIH Oct 23, 2020 Jan 5, 2024 R41/R42, R43/R44
Notice of Special Interest: NIGMS Priorities for Small Business Development of Sepsis Diagnostics and Therapeutics NOT-GM-20-028 NIGMS Jun 2, 2020 Sep 12, 2023 R41/R42, R43/R44, SB1
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