PAR-22-216 - NCI Clinical and Translational Exploratory/Developmental Studies (R21 Clinical Trial Optional) is used for the submission of applications to the following Notices of Special Interest (NOSIs)

Active NOSIs

Title Notice Number Organization Release
Date
Expiration
Date
Activity
Code(s)
Notice of Special Interest (NOSI): Advancing Diet and Physical Activity Biomarkers for Assessing Lifestyle Interventions in Cancer Prevention and Cancer Interception Research NOT-CA-24-074 NCI Jul 30, 2024 Jan 8, 2027 R01, R03, R21
Notice of Special Interest (NOSI): Factors impacting how Time-Restricted Eating (TRE) influences cancer-related outcomes NOT-CA-24-073 NCI Jul 9, 2024 May 8, 2027 R01, U34, K22, R21, K99/R00, K08, R34
Notice of Special Interest: Womens Health Research NOT-OD-24-079 ORWH , FIC , NCATS , NCCIH , NCI , NEI , NHGRI , NHLBI , NIA , NIAAA , NIAID , NIAMS , NIBIB , NICHD , NIDA , NIDCD , NIDCR , NIDDK , NIEHS , NIGMS , NIMH , NIMHD , NINDS , NINR , NLM , OAR , OBSSR , ODP , ODS , ODSS , SGMRO Mar 26, 2024 Nov 5, 2027 R15, R01, K01, R16, K08, R21, K43, F31, R43/R44, R41/R42, F30, R03, K23, F32, R34
Notice of Special Interest (NOSI): Research Projects to Develop Oncoaging Models for Cancer Research NOT-CA-23-092 NCI , NIA Oct 16, 2023 Jul 31, 2027 R21, R01
Notice of Special Interest (NOSI): Targeting the Endocannabinoid System for Brain Health and Acute and Chronic Diseases NOT-DA-22-048 NIDA , NCI , NIDCR Jan 9, 2023 Jan 8, 2026 R01, R21, DP2, DP1, K99/R00, K01, R36, K08, R15, K24
Notice of Special Interest (NOSI): Utilization of Cohorts and Prospective Study Designs for Liquid Biopsy Assay Validation for Early Detection of Cancers NOT-CA-23-004 NCI Oct 17, 2022 Jul 2, 2025 R43/R44, R21, R01, UH2/UH3, R41/R42, U01
Notice of Special Interest (NOSI): Basic Mechanisms of Cannabis and Cannabinoid Action in Cancer NOT-CA-22-085 NCI May 5, 2022 Jul 5, 2027 K22, R01, K08, K01, R21, R03, K99/R00

Expired NOSIs

Title Notice Number Organization Release
Date
Expiration
Date
Activity
Code(s)
Notice of Special Interest (NOSI): Advancing Diet and Physical Activity Biomarkers for Assessing Lifestyle Interventions in Cancer Prevention and Cancer Interception Research NOT-CA-24-060 NCI Jun 12, 2024 Aug 2, 2024 R01, R03, R21
Notice of Special Interest (NOSI): Research on the Etiology, Early Detection, Screening and Prevention of Early-Onset Colorectal Cancer NOT-CA-23-018 NCI Jan 19, 2023 Sep 8, 2024 K01, R01, K22, K08, R21, U34, K99/R00, P01, R34
Notice of Special Interest (NOSI): Improving Outcomes in Cancer Treatment-Related Cardiotoxicity NOT-CA-22-001 NCI NHLBI Nov 4, 2021 Nov 6, 2024 R01, R03, R21, P01
Notice of Special Interest (NOSI): Dietary Effects on Nutrient Sensing Pathways in Tumor Etiology and Prevention NOT-CA-21-121 NCI Oct 4, 2021 Sep 8, 2024 K22, K08, R15, R01, R21, K99/R00,
Notice of Special Interest (NOSI): Advancing the development of tumor site-activated small molecules NOT-CA-21-101 NCI Aug 16, 2021 Jan 8, 2024 R01, R15, R21

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