NIH Guide to Grants and Contracts

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Results: 51 to 75 of 1403

Display Results as:

Advances in Patient Safety through Simulation Research (R18) - PA-16-420

Organization: AHRQ 

Posting Date: 09-06-2016 

Expiration Date: 01-26-2022 

Activity Code: R18 

Summary: The Agency for Healthcare Research and Quality (AHRQ) is interested in funding a diverse set of projects that develop, test and evaluate various simulation approaches for the purpose of improving the safe delivery of health care. Simulation in health care serves multiple purposes. As a training technique, it exposes individuals and teams to realistic clinical challenges through the use of mannequins, task trainers, virtual reality, standardized patients or other forms, and allows participants to experience in real-time the consequences of their decisions and actions. The principal advantage of simulation is that it provides a safe environment for health care practitioners to acquire valuable experience without putting patients at risk. Simulation also can be used as a test-bed to improve clinical processes and to identify failure modes or other areas of concern in new procedures and technologies that might otherwise be unanticipated and serve as threats to patient safety. Yet another application of simulation focuses on the establishment of valid and reliable measures of clinical performance competency and their potential use for credentialing and certification purposes. The foremost aim of the announcement is to advance patient safety. Keeping this aim in mind, applications that address a variety of simulation techniques, clinical settings, provider groups, priority populations, and patient conditions are welcomed. 

Advances in Polycystic Kidney Disease (R01) - PA-16-159

Organization: NIDDK 

Posting Date: 03-30-2016 

Expiration Date: 05-08-2019 

Activity Code: R01 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to increase investigator interest in basic and applied investigations of the etiology and pathogenesis of Polycystic Kidney Disease (PKD), in both its autosomal dominant and autosomal recessive forms.The ultimate aim is to facilitate PKD-related research studies, which will provide the basis for new therapeutic approaches.  

Advancing Basic Neurobiology Toward Translation Through Assay Development (R01 Clinical Trials Not Allowed) - PAR-18-505

Organization: NIMH 

Posting Date: 12-18-2017 

Expiration Date: 01-08-2021 

Activity Code: R01 

Summary: This funding opportunity announcement (FOA) encourages research grant applications to develop novel, robust assays to reveal changes in neuronal and/or glial function. The goal is to adapt state-of-the-art measures of basic cellular processes or molecular events that are key mediators of nervous system function into phenotypic assays, with the intent to probe mechanisms or perturbations in an unbiased and efficient manner. These novel assays would provide opportunities to measure neurobiological endpoints to accelerate basic discovery and support target identification and therapeutic development efforts. 

Advancing Erythroid Cell Biology (R01) - PA-16-039

Organization: NIDDK 

Posting Date: 11-20-2015 

Expiration Date: 01-08-2019 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) encourages investigator-initiated applications that propose hypothesis-driven research using erythroid cells.The aim of this program is to support research efforts towards a complete description of the molecular and cellular components of erythropoiesis and how these components function to achieve normal erythropoiesis.Components include genes that are expressed (transcriptome) in erythroid cells, either during development or during differentiation, chemical changes to DNA and histone proteins (epigenome) and the proteins (proteome) that are translated in erythroid cells, including post-translational modifications or subcellular localizations that are unique to erythroid cells.A long range goal of this program is to generate a concise description of erythropoiesis that unifies genetics, molecular processes and cytokine determinants in the erythroid lineages so that new therapeutics may be developed to measure and combat anemia. 

Advancing Exceptional Research on HIV/AIDS and Substance Abuse (R01) - RFA-DA-18-002

Organization: NIDA 

Posting Date: 03-03-2017 

Expiration Date: 08-23-2019 

Activity Code: R01 

Summary: This FOA supports highly innovative R01 applications on HIV/AIDS and drug abuse and complements the Avant-Garde Award Program for HIV/AIDS and Drug Use Research and the Avenir Award Program for Research on Substance Abuse and HIV/AIDS. The Avant-Garde award supports individuals who conduct high-risk, high-reward research and does not require a detailed research plan. The Avenir award is similar to the Avant-Garde award but focuses on support for early stage investigators. Applications submitted under this FOA are required to have a detailed research plan and preliminary data. This FOA focuses on innovative research projects that have the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention and treatment of HIV/AIDS among substance abusers. The nexus with drug abuse should be clearly described. This FOA is open to both individual researchers and research teams and is not limited to any one area of research on HIV and substance use, but all studies must focus on NIH HIV/AIDS Research Priorities https://grants.nih.gov/grants/guide/notice-files/NOT-OD-15-137.html. 

Advancing Mechanistic Probiotic/Prebiotic and Human Microbiome Research (R01) - PA-15-135

Organization: NIDCR 

Posting Date: 03-09-2015 

Expiration Date: 05-08-2018 

Activity Code: R01 

Summary: The purpose of this funding opportunity announcement (FOA) is twofold: (1) to stimulate basic and mechanistic science that facilitates the development of effective probiotics or pre-/probiotic combinations of relevance to human health and disease; and (2) determine biological outcomes for the evaluation of efficacy of pre/probiotics in appropriate test systems and animal models. This FOA encourages basic and mechanistic studies using in vitro, in vivo, ex vivo, and in silico models that focus on prebiotic/probiotic strain selectivity, interaction, and function. It will also encourage inter and multidisciplinary collaborations among scientists in a wide range of disciplines including nutritional science, immunology, microbiomics, genomics, other '-omic' sciences, biotechnology, and bioinformatics.  

Advancing Our Understanding of the Brain Epitranscriptome (R21) - PAR-17-152

Organization: NIMH 

Posting Date: 02-03-2017 

Expiration Date: 05-08-2020 

Activity Code: R21 

Summary: The "epitranscriptome" refers to chemical modifications of RNA molecules. RNA modifications in the brain have been reported to regulate the fate and function of both coding and noncoding RNAs and are emerging as a critical element of cellular function. The purpose of this initiative is to stimulate research into the functions of modified RNAs in the brain and in the associated modification proteins that act on RNA (readers, writers, and erasers) that play a role in basic neurobiological and behavioral processes implicated in mental and substance use disorders.  

Advancing Patient Safety Implementation through Safe Medication Use Research (R18) - PA-16-421

Organization: AHRQ 

Posting Date: 09-06-2016 

Expiration Date: 09-26-2019 

Activity Code: R18 

Summary: The Agency for Healthcare Research and Quality's (AHRQ) mission is to produce evidence to make health care safer, higher quality, more accessible, equitable, and affordable, and to work within the U.S. Department of Health and Human Services and with other partners to make sure that the evidence is understood and used. 

Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R41/R42 Clinical Trial Optional) - PAS-18-188

Organization: NIA 

Posting Date: 11-28-2017 

Expiration Date: 09-06-2019 

Activity Code: R41/R42 

Summary: This Funding Opportunity Announcement (FOA) encourages applications to NIA's Small Business Technology Transfer Research (STTR)program to conduct research leading to the development of innovative products and/or services that may advance progress in preventing and treating Alzheimer's disease (AD) and Alzheimer's-disease-related dementias (ADRD) and/or caring for and treating AD/ADRD patients. 

Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R41/R42) - PAS-17-065

Organization: NIA 

Posting Date: 12-02-2016 

Expiration Date: 01-25-2018 

Activity Code: R41/R42 

Summary: This Funding Opportunity Announcement (FOA) encourages applications to NIA's Small Business Technology Transfer Research (STTR)program to conduct research leading to the development of innovative products and/or services that may advance progress in preventing and treating Alzheimer's disease (AD) and Alzheimer's-disease-related dementias (ADRD) and/or caring for and treating AD/ADRD patients. 

Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R43/R44 Clinical Trial Optional) - PAS-18-187

Organization: NIA 

Posting Date: 11-28-2017 

Expiration Date: 09-06-2019 

Activity Code: R43/R44 

Summary: This Funding Opportunity Announcement (FOA) encourages applications to NIA's Small Business Innovation Research (SBIR) program to conduct research leading to the development of innovative products and/or services that may advance progress in preventing and treating Alzheimer's disease (AD) and Alzheimer's-disease-related dementias (ADRD) and/or caring for and treating AD/ADRD patients. 

Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R43/R44) - PAS-17-064

Organization: NIA 

Posting Date: 12-02-2016 

Expiration Date: 01-25-2018 

Activity Code: R43/R44 

Summary: This Funding Opportunity Announcement (FOA) encourages applications to NIA's Small Business Innovation Research (SBIR) program to conduct research leading to the development of innovative products and/or services that may advance progress in preventing and treating Alzheimer's disease (AD) and Alzheimer's-disease-related dementias (ADRD) and/or caring for and treating AD/ADRD patients. 

Advancing Translational and Clinical Probiotic/Prebiotic and Human Microbiome Research (R01 Clinical Trial Optional) - PA-18-001

Organization: NCI 

Posting Date: 11-01-2017 

Expiration Date: 05-08-2018 

Activity Code: R01 

Summary: The purpose of this funding opportunity announcement (FOA) is twofold: 1. to accelerate translational and clinical Phase I and II a/b safety and efficacy studies for substantiating measurable functional benefits of probiotic/prebiotic components and/or their combinations; and; 2. to understand the underlying mechanisms of their action(s), and variability in responses to these interventions. This FOA calls for interdisciplinary collaborations across scientific disciplines engaged in microbiome and pro/prebiotic research including, but not limited to: nutritional science, microbiology, virology, microecology and microbiome, genomics, immunology, computational biology, chemistry, bioengineering, as well as integration of omics and computational approaches in DNA technologies. This FOA will not support phase III clinical trials. 

Advancing Translational and Clinical Probiotic/Prebiotic and Human Microbiome Research (R01) - PA-15-127

Organization: NCI 

Posting Date: 02-26-2015 

Expiration Date: 01-25-2018 

Activity Code: R01 

Summary: The purpose of this funding opportunity announcement (FOA) is twofold: 1. to accelerate translational and clinical Phase I and II a/b safety and efficacy studies for substantiating measurable functional benefits of probiotic/prebiotic components and/or their combinations; and; 2. to understand the underlying mechanisms of their action(s), and variability in responses to these interventions. This FOA calls for interdisciplinary collaborations across scientific disciplines engaged in microbiome and pro/prebiotic research including, but not limited to: nutritional science, microbiology, virology, microecology and microbiome, genomics, immunology, computational biology, chemistry, bioengineering, as well as integration of omics and computational approaches in DNA technologies. This FOA will not support phase III clinical trials. 

Advancing Understanding, Prevention and Management of Infections Transmitted from Women to their Infants (R21 Clinical Trial Optional) - PA-18-092

Organization: NICHD 

Posting Date: 11-02-2017 

Expiration Date: 09-08-2019 

Activity Code: R21 

Summary: The purpose of this funding opportunity announcement (FOA) is to stimulate investigations including translational, epidemiologic and clinical studies and trials that improve the understanding, prevention and clinical outcomes of non-HIV infections transmitted from women to their offspring during pregnancy, labor and delivery, and breastfeeding. NICHD is committed to supporting research that will increase scientific understanding of and treatments for high-priority perinatal infections. 

Advancing Understanding, Prevention and Management of Infections Transmitted from Women to their Infants (R21) - PA-16-031

Organization: NICHD 

Posting Date: 11-05-2015 

Expiration Date: 01-25-2018 

Activity Code: R21 

Summary: The purpose of this funding opportunity announcement (FOA) is to stimulate investigations including translational, epidemiologic and clinical studies and trials that improve the understanding, prevention and clinical outcomes of non-HIV infections transmitted from women to their offspring during pregnancy, labor and delivery, and breastfeeding. NICHD is committed to supporting research that will increase scientific understanding of and treatments for high-priority perinatal infections. 

Advancing Understanding, Prevention, and Management of Infections Transmitted from Women to their Infants (R01 Clinical Trial Optional) - PA-18-031

Organization: NICHD 

Posting Date: 11-02-2017 

Expiration Date: 09-08-2019 

Activity Code: R01 

Summary: The purpose of this funding opportunity announcement (FOA) is to stimulate investigations including translational, epidemiologic and clinical studies and trials that improve the understanding, prevention and clinical outcomes of non-HIV infections transmitted from women to their offspring during pregnancy, labor and delivery, and breastfeeding. NICHD is committed to supporting research that will increase scientific understanding of and treatments for high-priority perinatal infections. 

Advancing Understanding, Prevention, and Management of Infections Transmitted from Women to their Infants (R01) - PA-16-032

Organization: NICHD 

Posting Date: 11-05-2015 

Expiration Date: 01-25-2018 

Activity Code: R01 

Summary: The purpose of this funding opportunity announcement (FOA) is to stimulate investigations including translational, epidemiologic and clinical studies and trials that improve the understanding, prevention and clinical outcomes of non-HIV infections transmitted from women to their offspring during pregnancy, labor and delivery, and breastfeeding. NICHD is committed to supporting research that will increase scientific understanding of and treatments for high-priority perinatal infections. 

Advancing our Understanding of the Brain Epitranscriptomics (R01) - PAR-17-153

Organization: NIMH 

Posting Date: 02-03-2017 

Expiration Date: 05-08-2020 

Activity Code: R01 

Summary: The "epitranscriptome" refers to chemical modifications of RNA molecules. RNA modifications in the brain have been reported to regulate the fate and function of both coding and noncoding RNAs and are emerging as a critical element of cellular function. The purpose of this initiative is to stimulate research into the functions of modified RNAs in the brain and/or the associated modification proteins that act on RNA (readers, writers, and erasers) and play a role in basic neurobiological and behavioral processes implicated in mental and substance use disorders.  

Advancing the Science of Geriatric Palliative Care (R01 - Clinical Trial Optional) - PA-18-502

Organization: NIA 

Posting Date: 12-15-2017 

Expiration Date: 05-08-2020 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) encourages research grant applications focused on palliative care in geriatric populations. This FOA covers studies in a variety of settings including hospitals (and specific sites within hospitals including specialty medical or surgical wards, intensive care units, and emergency departments), post-acute care settings, outpatient clinics and doctors offices, patients homes and other residential settings, assisted living facilities, nursing homes, hospices, and other healthcare or community settings. This FOA encourages both prospective studies and analyses of existing datasets, health and medical records, claims data, or other sources. Leveraging ongoing cohorts, intervention studies, networks, data and specimen repositories, and other existing research resources and infrastructure are encouraged. Study designs may include observational approaches, quasi-experimental designs, and interventional studies. 

Advancing the Science of Geriatric Palliative Care (R21 - Clinical Trial Optional) - PA-18-503

Organization: NIA 

Posting Date: 12-15-2017 

Expiration Date: 05-08-2020 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) encourages exploratory or developmental research grant applications to develop new tools, methods, and models focused on palliative care in geriatric populations. This FOA covers studies in a variety of settings including hospitals (and specific sites within hospitals including specialty medical or surgical wards, intensive care units, and emergency departments), post-acute care settings, outpatient clinics and doctors offices, patients homes and other residential settings, assisted living facilities, nursing homes, hospices, and other healthcare or community settings. This FOA encourages both prospective studies and analyses of existing datasets, health and medical records, claims data, or other sources. Leveraging ongoing cohorts, intervention studies, networks, data and specimen repositories, and other existing research resources and infrastructure are encouraged. Study designs may include observational approaches, quasi-experimental designs, and limited interventional studies where feasible for this R21 mechanism. 

Advancing the Science of Multipurpose Technology for the Prevention of HIV and Unintended Pregnancy (R41/R42) - RFA-HD-18-101

Organization: NICHD 

Posting Date: 11-22-2017 

Expiration Date: 01-23-2018 

Activity Code: R41/R42 

Summary: The purpose of this initiative is to invite STTR applications to stimulate new and innovative multipurpose prevention technologies (MPTs) through the development of new combinations of agents and delivery systems to prevent HIV infection and unintended pregnancy among adolescent girls and young women. HIV and unintended pregnancy are two major public health problems affecting young women globally. Combination prevention modalities may be more desirable and lead to better adherence in the end user, especially among younger populations. A viable and effective combination prevention modality would be ideal and critical for these young women who are at risk for HIV and who desire protection against pregnancy. 

Advancing the Science of Multipurpose Technology for the Prevention of HIV and Unintended Pregnancy (R43/R44) - RFA-HD-18-102

Organization: NICHD 

Posting Date: 11-22-2017 

Expiration Date: 01-23-2018 

Activity Code: R43/R44 

Summary: The purpose of this initiative is to invite SBIR applications to stimulate new and innovative multipurpose prevention technologies (MPTs) through the development of new combinations of agents and delivery systems to prevent HIV infection and unintended pregnancy among adolescent girls and young women. HIV and unintended pregnancy are two major public health problems affecting young women globally. Combination prevention modalities may be more desirable and lead to better adherence in the end user, especially among younger populations. A viable and effective combination prevention modality would be ideal and critical for these young women who are at risk for HIV and who desire protection against pregnancy. 

African Association for Health Professions Education and Research (R25)(Clinical Trials Not Allowed) - RFA-TW-18-001

Organization: FIC 

Posting Date: 01-12-2018 

Expiration Date: 03-29-2018 

Activity Code: R25 

Summary: The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this Fogarty International Center R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs by supporting the establishment of an African Association for Health Professions Education and Research (the "Association"). The Association will serve as a leadership and convening organization to network institutions across sub-Saharan Africa in order to jointly develop, disseminate, and share best practices, innovations, curricula, and policy and to engage in joint activities that will increase the quantity, quality and retention of African health professionals to address the crisis in HIV/AIDS and its' comorbidities on the continent. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on one or more of the following: Courses for Skills Development, Research Experiences, Mentoring Activities, Curriculum or Methods Development, and Outreach to broad communities and multiple stakeholders. 

Agency for Healthcare Research and Quality (AHRQ)-sponsored National Research Service Award (NRSA)Individual Postdoctoral Fellowship (F32) - PA-17-481

Organization: AHRQ 

Posting Date: 09-12-2017 

Expiration Date: 08-09-2022 

Activity Code: F32 

Summary: The purpose of this individual postdoctoral research training fellowship is to enhance the research training of promising postdoctoral candidates who have the potential to become productive, independent investigators in health services research, with a research interest in areas and priorities relevant to the mission of AHRQ.  

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