NIH Guide to Grants and Contracts

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Results: 51 to 75 of 1244

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Advancing Erythroid Cell Biology (R01) - PA-16-039

Organization: NIDDK 

Posting Date: 11-20-2015 

Expiration Date: 01-08-2019 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) encourages investigator-initiated applications that propose hypothesis-driven research using erythroid cells.The aim of this program is to support research efforts towards a complete description of the molecular and cellular components of erythropoiesis and how these components function to achieve normal erythropoiesis.Components include genes that are expressed (transcriptome) in erythroid cells, either during development or during differentiation, chemical changes to DNA and histone proteins (epigenome) and the proteins (proteome) that are translated in erythroid cells, including post-translational modifications or subcellular localizations that are unique to erythroid cells.A long range goal of this program is to generate a concise description of erythropoiesis that unifies genetics, molecular processes and cytokine determinants in the erythroid lineages so that new therapeutics may be developed to measure and combat anemia. 

Advancing Exceptional Research on HIV/AIDS and Substance Abuse (R01, Clinical Trial Optional) - RFA-DA-18-022

Organization: NIDA 

Posting Date: 03-14-2018 

Expiration Date: 08-22-2020 

Activity Code: R01 

Summary: This FOA supports highly innovative R01 applications on HIV/AIDS and drug abuse and complements the Avant-Garde Award Program for HIV/AIDS and Drug Use Research and the Avenir Award Program for Research on Substance Abuse and HIV/AIDS. The Avant-Garde award supports individuals who conduct high-risk, high-reward research and does not require a detailed research plan. The Avenir award is similar to the Avant-Garde award but focuses on support for early stage investigators. Applications submitted under this FOA are required to have a detailed research plan and preliminary data. This FOA focuses on innovative research projects that have the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention and treatment of HIV/AIDS among substance abusers. The nexus with drug abuse should be clearly described. This FOA is open to both individual researchers and research teams and is not limited to any one area of research on HIV and substance use, but all studies must focus on NIH HIV/AIDS Research Priorities https://grants.nih.gov/grants/guide/notice-files/NOT-OD-15-137.html. 

Advancing Mechanistic Probiotic/Prebiotic and Human Microbiome Research (R01) - PA-15-135

Organization: NIDCR 

Posting Date: 03-09-2015 

Expiration Date: 05-08-2018 

Activity Code: R01 

Summary: The purpose of this funding opportunity announcement (FOA) is twofold: (1) to stimulate basic and mechanistic science that facilitates the development of effective probiotics or pre-/probiotic combinations of relevance to human health and disease; and (2) determine biological outcomes for the evaluation of efficacy of pre/probiotics in appropriate test systems and animal models. This FOA encourages basic and mechanistic studies using in vitro, in vivo, ex vivo, and in silico models that focus on prebiotic/probiotic strain selectivity, interaction, and function. It will also encourage inter and multidisciplinary collaborations among scientists in a wide range of disciplines including nutritional science, immunology, microbiomics, genomics, other '-omic' sciences, biotechnology, and bioinformatics.  

Advancing Our Understanding of the Brain Epitranscriptome (R21) - PAR-17-152

Organization: NIMH 

Posting Date: 02-03-2017 

Expiration Date: 05-08-2020 

Activity Code: R21 

Summary: The "epitranscriptome" refers to chemical modifications of RNA molecules. RNA modifications in the brain have been reported to regulate the fate and function of both coding and noncoding RNAs and are emerging as a critical element of cellular function. The purpose of this initiative is to stimulate research into the functions of modified RNAs in the brain and in the associated modification proteins that act on RNA (readers, writers, and erasers) that play a role in basic neurobiological and behavioral processes implicated in mental and substance use disorders.  

Advancing Patient Safety Implementation through Safe Medication Use Research (R18) - PA-16-421

Organization: AHRQ 

Posting Date: 09-06-2016 

Expiration Date: 09-26-2019 

Activity Code: R18 

Summary: The Agency for Healthcare Research and Quality's (AHRQ) mission is to produce evidence to make health care safer, higher quality, more accessible, equitable, and affordable, and to work within the U.S. Department of Health and Human Services and with other partners to make sure that the evidence is understood and used. 

Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R41/R42 Clinical Trial Optional) - PAS-18-188

Organization: NIA 

Posting Date: 11-28-2017 

Expiration Date: 09-06-2019 

Activity Code: R41/R42 

Summary: This Funding Opportunity Announcement (FOA) encourages applications to NIA's Small Business Technology Transfer Research (STTR)program to conduct research leading to the development of innovative products and/or services that may advance progress in preventing and treating Alzheimer's disease (AD) and Alzheimer's-disease-related dementias (ADRD) and/or caring for and treating AD/ADRD patients. 

Advancing Research on Alzheimer's Disease (AD) and Alzheimer's-Disease-Related Dementias (ADRD) (R43/R44 Clinical Trial Optional) - PAS-18-187

Organization: NIA 

Posting Date: 11-28-2017 

Expiration Date: 09-06-2019 

Activity Code: R43/R44 

Summary: This Funding Opportunity Announcement (FOA) encourages applications to NIA's Small Business Innovation Research (SBIR) program to conduct research leading to the development of innovative products and/or services that may advance progress in preventing and treating Alzheimer's disease (AD) and Alzheimer's-disease-related dementias (ADRD) and/or caring for and treating AD/ADRD patients. 

Advancing Translational and Clinical Probiotic/Prebiotic and Human Microbiome Research (R01 Clinical Trial Optional) - PA-18-001

Organization: NCI 

Posting Date: 11-01-2017 

Expiration Date: 05-08-2018 

Activity Code: R01 

Summary: The purpose of this funding opportunity announcement (FOA) is twofold: 1. to accelerate translational and clinical Phase I and II a/b safety and efficacy studies for substantiating measurable functional benefits of probiotic/prebiotic components and/or their combinations; and; 2. to understand the underlying mechanisms of their action(s), and variability in responses to these interventions. This FOA calls for interdisciplinary collaborations across scientific disciplines engaged in microbiome and pro/prebiotic research including, but not limited to: nutritional science, microbiology, virology, microecology and microbiome, genomics, immunology, computational biology, chemistry, bioengineering, as well as integration of omics and computational approaches in DNA technologies. This FOA will not support phase III clinical trials. 

Advancing Understanding, Prevention and Management of Infections Transmitted from Women to their Infants (R21 Clinical Trial Optional) - PA-18-092

Organization: NICHD 

Posting Date: 11-02-2017 

Expiration Date: 09-08-2019 

Activity Code: R21 

Summary: The purpose of this funding opportunity announcement (FOA) is to stimulate investigations including translational, epidemiologic and clinical studies and trials that improve the understanding, prevention and clinical outcomes of non-HIV infections transmitted from women to their offspring during pregnancy, labor and delivery, and breastfeeding. NICHD is committed to supporting research that will increase scientific understanding of and treatments for high-priority perinatal infections. 

Advancing Understanding, Prevention, and Management of Infections Transmitted from Women to their Infants (R01 Clinical Trial Optional) - PA-18-031

Organization: NICHD 

Posting Date: 11-02-2017 

Expiration Date: 09-08-2019 

Activity Code: R01 

Summary: The purpose of this funding opportunity announcement (FOA) is to stimulate investigations including translational, epidemiologic and clinical studies and trials that improve the understanding, prevention and clinical outcomes of non-HIV infections transmitted from women to their offspring during pregnancy, labor and delivery, and breastfeeding. NICHD is committed to supporting research that will increase scientific understanding of and treatments for high-priority perinatal infections. 

Advancing our Understanding of the Brain Epitranscriptomics (R01) - PAR-17-153

Organization: NIMH 

Posting Date: 02-03-2017 

Expiration Date: 05-08-2020 

Activity Code: R01 

Summary: The "epitranscriptome" refers to chemical modifications of RNA molecules. RNA modifications in the brain have been reported to regulate the fate and function of both coding and noncoding RNAs and are emerging as a critical element of cellular function. The purpose of this initiative is to stimulate research into the functions of modified RNAs in the brain and/or the associated modification proteins that act on RNA (readers, writers, and erasers) and play a role in basic neurobiological and behavioral processes implicated in mental and substance use disorders.  

Advancing the Science of Geriatric Palliative Care (R01 - Clinical Trial Optional) - PA-18-502

Organization: NIA 

Posting Date: 12-15-2017 

Expiration Date: 05-08-2020 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) encourages research grant applications focused on palliative care in geriatric populations. This FOA covers studies in a variety of settings including hospitals (and specific sites within hospitals including specialty medical or surgical wards, intensive care units, and emergency departments), post-acute care settings, outpatient clinics and doctors offices, patients homes and other residential settings, assisted living facilities, nursing homes, hospices, and other healthcare or community settings. This FOA encourages both prospective studies and analyses of existing datasets, health and medical records, claims data, or other sources. Leveraging ongoing cohorts, intervention studies, networks, data and specimen repositories, and other existing research resources and infrastructure are encouraged. Study designs may include observational approaches, quasi-experimental designs, and interventional studies. 

Advancing the Science of Geriatric Palliative Care (R21 - Clinical Trial Optional) - PA-18-503

Organization: NIA 

Posting Date: 12-15-2017 

Expiration Date: 05-08-2020 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) encourages exploratory or developmental research grant applications to develop new tools, methods, and models focused on palliative care in geriatric populations. This FOA covers studies in a variety of settings including hospitals (and specific sites within hospitals including specialty medical or surgical wards, intensive care units, and emergency departments), post-acute care settings, outpatient clinics and doctors offices, patients homes and other residential settings, assisted living facilities, nursing homes, hospices, and other healthcare or community settings. This FOA encourages both prospective studies and analyses of existing datasets, health and medical records, claims data, or other sources. Leveraging ongoing cohorts, intervention studies, networks, data and specimen repositories, and other existing research resources and infrastructure are encouraged. Study designs may include observational approaches, quasi-experimental designs, and limited interventional studies where feasible for this R21 mechanism. 

Age-related Microbiota Changes and their Implications in Chronic Disease Prevention, Treatment and Progression (R01 Clinical Trial Optional). - PA-18-738

Organization: NCI 

Posting Date: 04-03-2018 

Expiration Date: 05-08-2021 

Activity Code: R01 

Summary: The overall purpose of this funding opportunity announcement (FOA) is to assess the role of the microbiome in health and disease during aging. This initiative will support research projects designed to evaluate changes in the microbiota during lifetime and its influence in health and disease status in the elderly, including those from racial/ethnic minority and underserved populations and understand the underlying mechanisms of microbiota interactions in aged subjects as related to health and disease. This FOA will accept basic mechanistic, preclinical studies in animal models and human clinical trial proposals in accordance with the state of the science. 

Age-related Microbiota Changes and their Implications in Chronic Disease Prevention, Treatment and Progression (R21 Clinical Trial Optional). - PA-18-739

Organization: NCI 

Posting Date: 04-03-2018 

Expiration Date: 05-08-2021 

Activity Code: R21 

Summary: The overall purpose of this funding opportunity announcement (FOA) is to assess the role of the microbiome in health and disease during aging. This initiative will support research projects designed to evaluate changes in the microbiota during lifetime and its influence in health and disease status in the elderly, including those from racial/ethnic minority and underserved populations and understand the underlying mechanisms of microbiota interactions in aged subjects as related to health and disease. This FOA will accept basic mechanistic, preclinical studies in animal models and human clinical trial proposals in accordance with the state of the science. 

Agency for Healthcare Research and Quality (AHRQ)-sponsored National Research Service Award (NRSA)Individual Postdoctoral Fellowship (F32) - PA-17-481

Organization: AHRQ 

Posting Date: 09-12-2017 

Expiration Date: 08-09-2022 

Activity Code: F32 

Summary: The purpose of this individual postdoctoral research training fellowship is to enhance the research training of promising postdoctoral candidates who have the potential to become productive, independent investigators in health services research, with a research interest in areas and priorities relevant to the mission of AHRQ.  

Aging Research Dissertation Awards to Increase Diversity (R36) - PAR-17-025

Organization: NIA 

Posting Date: 10-20-2016 

Expiration Date: 01-08-2020 

Activity Code: R36 

Summary: The purpose of this Funding Opportunity Announcement (FOA) is to provide dissertation awards in all areas of research within NIAs strategic priorities to increase diversity of the scientific research workforce engaged in research on aging and aging-related health conditions. 

Alcohol Impairment of Immune Function, Host Defense and Tissue Homeostasis (R01 Clinical Trial Optional) - PA-18-191

Organization: NIAAA 

Posting Date: 11-01-2017 

Expiration Date: 05-08-2018 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) invites applications from researchers with broad expertise to study the consequences of alcohol consumption on immune function with a goal toward improving the outcome of patients who abuse alcohol.  

Alcohol Research Resource Awards (R24) - PAR-17-170

Organization: NIAAA 

Posting Date: 02-21-2017 

Expiration Date: 05-08-2020 

Activity Code: R24 

Summary: This funding opportunity announcement encourages non-hypothesis-driven grant applications to support investigator-initiated research projects that will maintain and expand the availability of resources to serve biomedical research within NIAAAs priority areas as described in the strategic plan. 

Alcohol Use Disorders: Behavioral Treatment, Services and Recovery Research (R01 Clinical Trial Optional) - PA-18-194

Organization: NIAAA 

Posting Date: 11-06-2017 

Expiration Date: 09-08-2018 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) encourages grant applications from institutions/organizations that propose to support research on behavioral treatment for alcohol use disorders; organizational, financial, and management factors that facilitate or inhibit the delivery of services for alcohol use disorders; and phenomenon of recovery from alcohol use disorders. 

Alcohol Use Disorders: Behavioral Treatment, Services and Recovery Research (R03 Clinical Trial Optional) - PA-18-201

Organization: NIAAA 

Posting Date: 11-06-2017 

Expiration Date: 09-08-2018 

Activity Code: R03 

Summary: This Funding Opportunity Announcement (FOA) encourages grant applications from institutions/organizations that propose to support research on behavioral treatment for alcohol use disorders; organizational, financial, and management factors that facilitate or inhibit the delivery of services for alcohol use disorders; and phenomenon of recovery from alcohol use disorders. 

Alcohol Use Disorders: Behavioral Treatment, Services and Recovery Research (R21 Clinical Trial Optional) - PA-18-202

Organization: NIAAA 

Posting Date: 11-06-2017 

Expiration Date: 09-08-2018 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) encourages grant applications from institutions/organizations that propose to support research on behavioral treatment for alcohol use disorders; organizational, financial, and management factors that facilitate or inhibit the delivery of services for alcohol use disorders; and phenomenon of recovery from alcohol use disorders. 

Alcohol-Induced Effects on Tissue Injury and Repair (R01) - PA-17-297

Organization: NIAAA 

Posting Date: 05-25-2017 

Expiration Date: 09-08-2020 

Activity Code: R01 

Summary: This Funding Opportunity Announcement (FOA) encourages Research Project Grant (R01) applications to study molecular and cellular mechanisms of tissue injury and repair associated with alcohol use in humans. Excessive alcohol consumption has the potential to adversely affect multiple organ systems including the liver, brain, heart, pancreas, lung, kidney, endocrine and immune systems, as well as bone and skeletal muscle. In addition, there is accumulating evidence that long term alcohol consumption is associated with reduced host capacity for recovery and repair following trauma. The mechanisms for these alcohol-induced effects on tissue injury and repair are currently not fully understood. NIAAA is especially interested in integrative research that elucidates alcohols effects on complex mechanisms of injury and repair that are either common or specific to each organ system. This FOA also encourages the study of alcohols effect on stem cells, embryonic development, and regeneration. Also encourages are studies on molecular and cellular actions of moderate alcohol consumption. A better understanding of these underlying mechanisms may provide new avenues for developing more effective and novel approaches for prognosis, diagnosis, intervention, and treatment of alcohol-induced organ damage. 

Alcohol-Induced Effects on Tissue Injury and Repair (R21) - PA-17-296

Organization: NIAAA 

Posting Date: 05-25-2017 

Expiration Date: 09-08-2020 

Activity Code: R21 

Summary: This Funding Opportunity Announcement (FOA) encourages Exploratory/Developmental Research Grant Award (R21) applications to study molecular and cellular mechanisms of tissue injury and repair associated with alcohol use in humans. Excessive alcohol consumption has the potential to adversely affect multiple organ systems including the liver, brain, heart, pancreas, lung, kidney, endocrine and immune systems, as well as bone and skeletal muscle. In addition, there is accumulating evidence that long term alcohol consumption is associated with reduced host capacity for recovery and repair following trauma. The mechanisms for these alcohol-induced effects on tissue injury and repair are currently not fully understood. NIAAA is especially interested in integrative research that elucidates alcohols effects on complex mechanisms of injury and repair that are either common or specific to each organ system. This FOA also encourages the study of alcohols effect on stem cells, embryonic development, and regeneration. Also encourages are studies on molecular and cellular actions of moderate alcohol consumption. A better understanding of these underlying mechanisms may provide new avenues for developing more effective and novel approaches for prognosis, diagnosis, intervention, and treatment of alcohol-induced organ damage. 

Alliance of Glycobiologists for Cancer Research: Biological Tumor Glycomics Laboratories (U01) - PAR-17-207

Organization: NCI 

Posting Date: 03-08-2017 

Expiration Date: 02-08-2019 

Activity Code: U01 

Summary: This Funding Opportunity Announcement (FOA) is intended to support research applications that are focused on mechanisms that mediate alterations in glycosylation during oncogenesis. The goal of this FOA is to advance our knowledge of altered glycosylation or other modifications in carbohydrate structure in cancer to determine whether it is the cause or the result of neoplastic transformation. Because the research is intended to examine the biology of how modifications in carbohydrate structure influence malignancy during different stages of the disease, this FOA will support research teams that have complementary expertise in glycobiology and cancer biology to focus on mechanisms that mediate alterations in glycosylation during oncogenesis. 

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