National Institute of General Medical Sciences (NIGMS)

• Acquisition of a single unit of equipment for the benefit of the project's research plan.
  • For RPGs, the direct costs may not exceed $250,000.
  • For centers and resources, direct costs should not exceed $250,000 without prior consultation with the assigned Program Officer (PO).
  • If requesting a partial amount of the purchase price, explain how the balance of funds will be provided from institutional/other sources via a letter of support.
  • This type of supplement cannot be made in the first year of a new award and generally will not be made in the final year.
• Modernization of IDeA CTR clinical trial and human subjects management software systems, electronic health record systems interoperability .
• Enhancements of the IDeA CTR practice-based research networks (PBRNs), particularly electronic health record systems.
• Consolidation of core facilities supported by IDeA COBRE, INBRE, and CTR grants

For questions about eligibility, please contact your PO(s) prior to submitting applications.

Applicants are encouraged to submit requests on or before April 18th to be considered for the current fiscal year. Requests received after April 18th may not be considered until the next fiscal year.

Program Contact:

The Program Officer listed on the NoA of the most recent parent award.

Grants management Contact:

The Grants Management Specialist or Grants Management Officer listed on the NoA of the most recent parent award.

• NIGMS will only support conferences or meetings that:
  • Are focused on basic biomedical research and research training topics closely aligned with NIGMS’ central mission and interests, and
    • Include participants and speakers who do not frequently interact in other venues, and
    • Are held at domestic sites.
• NIGMS will consider support for meetings that focus on research training and/or workforce development or are in support of programs that build research capacity.
• NIGMS anticipates funding very few conference or meeting grants. Simply because a meeting falls within the general areas of science or training and workforce development supported by NIGMS does not mean that the Institute will support the meeting. NIGMS rarely supports an R13 application as a secondary assignment.

• In general, NIGMS support for meetings and conferences is limited to under $10,000.

• The earliest start date for an award must be prior to the meeting start date.
• Apply early to provide at least 10 months before the meeting start date.

• Meetings funded by NIGMS may be awarded for up to 5 years. NIGMS does not support recurring or potentially recurring meetings except for those that focus on research training, workforce development, or research capacity building.

NIGMS DEA Mailbox

[email protected]

NIGMS prioritizes mentored career development applications relevant to its mission that demonstrate compelling career development needs and strong plans to address those needs.    

NIGMS prioritizes mentored career development awards that promote:  

• Clinician-scientist career development in basic or patient-oriented research in NIGMS-mission relevant clinical areas: 
  • Anesthesiology  
  • Clinical pharmacology 
  • Injury and critical illness.   
• Quantitative scientist career development to attract investigators whose quantitative science and engineering research has not yet focused primarily on biomedical topics to integrate their expertise with NIGMS-relevant research. 
• Pathway to independence awards to facilitate a timely transition of promising postdoctoral researchers from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions in all areas of the NIGMS mission.   

NIGMS strongly encourages applications from:  

• Institutions from IDeA-eligible states 
• HBCUs  
• Tribal Colleges and Universities (TCUs), as defined under 25 U.S.C. 1603 (24). 
• Resource-limited institutions that can support rigorous career development programs.

NIGMS will contribute up to the following amounts in salary and fringe benefits/per year, consistent with the established salary structure at the applicant institution to other staff members of equivalent qualifications, rank, and responsibilities in the department concerned. 

Clinician-scientist career development: Up to $50,000  

Quantitative scientist career development: Up to $50,000  

Pathway to Independence awards: Up to $25,000   

Funds may be used for 

• research-related expenses, such as supplies, equipment and technical personnel 
• tuition and fees related to career development 
• travel to research meetings or training 
• statistical services including personnel and computer time 

Salaries for mentors, secretarial and administrative assistants, etc. are not allowed. 

• For all mentored career development awards, NIGMS expects scholars to devote a minimum of 9 person months (75% of full-time professional effort) to the award.    
  • Note: Surgeon-scientists with surgical duties may devote a minimum of 6 person-months (50% full-time professional effort) to the award. 

Clinician-scientist career development  
[email protected]  

Quantitative scientist career development  
[email protected] 

Pathway to Independence awards  
[email protected] 

NIGMS prioritizes applications relevant to all areas of its mission that demonstrate compelling training needs and propose strong plans to promote trainee skills and career development. NIGMS strongly encourages applications from IDeA-eligible states, HBCUs, TCUs, and resource-limited institutions that can support rigorous fellowship training (including institutions without NIGMS-funded institutional training awards).  

NIGMS only considers MD-PhD students at institutions without NIH-funded institutional predoctoral dual-degree training programs (F30). Additionally, NIGMS prioritizes:  

• Predoctoral candidates from laboratories and institutions with limited other NIH support (F31).  
• Predoctoral candidates who will conduct NIGMS mission research in the K00 phase (F99/K00). 
• Postdoctoral candidates with less than 2 years of postdoctoral experience at the time of application (F32).  
• Investigators for whom the experience will significantly enhance their research careers (F33). 

• F30: 4 years. 
• F31: 3 years.  
• F32: 3 years.    
• F33: 1 year.  
• F99/K00: Minimum of one-year F99 phase; up to 3 years K00 phase. 

• F99  
  • Stipend: NRSA level 
  • Institutional allowance: NRSA + $2000 for travel for program related activities.  
• K00 limits 
  • Salary: $70,000 
  • Research expenses: $5000 per year. 
  • Travel: $2000 per year. 

• F30: [email protected] 
• F31: [email protected] 
• F32: [email protected] 
• F33: [email protected] 
• F99: [email protected] 

NIGMS prioritizes Institutional Career Development Programs relevant to its mission that prepare postdoctoral researchers for the following career pathways: 

• Clinician Scientist Research Independence (CSRI): Prepares clinician scientists for independent, research careers in NIGMS-mission relevant clinical areas: 
  • Anesthesiology  
  • Clinical pharmacology 
  • Injury and critical illness   

NIGMS anticipates that CSRI programs will recruit 2-4 new scholars annually and support them for two years for a maximum program size of 8 scholars.  At the conclusion of the program, scholars are expected to be able to successfully compete for mentored career development or independent research awards.   

• Academic Research and Teaching (ART): Prepares research scientists for academic careers that combine rigorous research and state-of-the art teaching approaches.  Programs are expected to combine mentored postdoctoral research experiences with mentored teaching and professional skills development opportunities at distinct primarily undergraduate teaching partner institutions. NIGMS anticipates that ART will recruit 3-4 new scholars annually and support them for three years for a maximum program size of 12 scholars.  At the conclusion of the experience, scholars are expected to be able to successfully transition to faculty careers at a range of institution types and compete for independent research support.   

NIGMS strongly encourages applications from:  

• Institutions from IDeA-eligible states 
• HBCUs  
• Tribal Colleges and Universities (TCUs), as defined under 25 U.S.C. 1603 (24). 
• Resource-limited institutions that can support rigorous career development programs.   

NIGMS also encourages the participation of these institutions as partners in career development programs, especially Academic Research and Teaching (ART).

Applications are considered for funding after October and January councils. Although applications are accepted for all opportunity due dates, we recommend submitting to due dates that align with those councils.

Support for up to 5 years. 

NIGMS will contribute up to the following amounts in salary and fringe benefits/per year, consistent with the established salary structure at the applicant institution to other staff members of equivalent qualifications, rank, and responsibilities in the department concerned. 

Salary support: Depending on the number of scholars in the program and the person-months devoted to administration of the program:

• Total PD(s)/PI(s) (including a combination of multiple PD(s)/PI(s)) is limited to up to a total of 2.0 person-months effort per year.
• Total salary support for other administrative staff (for example, a program coordinator to assist the PD(s)/PI(s)) is limited to up to 6 person-months.

Additionally, for ART partner institution(s), total salary support limits per partner organization are:

• 0.6 person months for administrative personnel.
• 2.4 person months for the teaching mentor(s).

Program evaluation: Limited program evaluation costs are allowed up to a maximum of 2% of direct costs per year for the 5-year project period. This includes salaries for evaluation consultants, if any.

Additional information by program area:

CSRI

• Up to $25,000 research support.
• $2,000 for conference travel

ART 

• Up to $2,500 for teaching supplies 
• Up to $2,000 for conference travel

CSRI  

• A minimum of 9 person-months (75% of full-time professional effort) to the award.    
• Surgeon-scientists with surgical duties may request a minimum of 6 person-months (50% full-time professional effort) to the award.  

ART 

• 9 person-months (75% full-time effort) to mentored research experiences. 
• 3 person-months (25% full-time effort) to mentored teaching and skills development activities each year, the timing of which may be flexible over the academic year.   

[email protected]  

NIGMS prioritizes Institutional Training relevant to its mission in three areas. Training programs should be well integrated within one or more departments and have a strong, positive influence on the institution’s research training and mentoring practices. To promote broad geographic and organizational participation in rigorous training programs, NIGMS strongly encourages applications from:  

• Institutions from IDeA-eligible states 
• HBCUs  
• Tribal Colleges and Universities (TCUs), as defined under 25 U.S.C. 1603 (24). 
• Resource-limited institutions that don’t yet have NIH training programs.    

• NIGMS prioritizes funding for the following trainees: 
  • Undergraduate 
  • Predoctoral 
    • Ph.D. only 
    • Clinician-scientist dual degree training  
• NIGMS does not support: 
  • Short-term training.  
  • Programs that support trainees at multiple career stages. 
• For institutional support for postdoctoral scientists, see NIGMS Institutional Career Development Programs interests. 

Applications are considered for funding after October and January councils. Although applications are accepted for all opportunity due dates, we recommend submitting to due dates that align with those councils

Support for up to 5 years. 

Biomedical Undergraduate Research Training  
[email protected]      

Medical Scientist Training Programs (MSTP)  
[email protected]   

Predoctoral Basic Biomedical Training  
[email protected] 

NIGMS programs cover a range of disciplines relevant to its mission and support participants who will significantly benefit, including those: 

• Without substantial previous research experience, 
• From resource-limited institutions, or 
• With circumstances that would otherwise prevent them from pursuing biomedical research. Such circumstances might include but are not necessarily limited to:
  • Financial hardship
  • Return from military service
  • Career delay or change
  • Family responsibilities  

Programs that recruit participants from a single organization or focus on a single discipline – especially those in the mission of other ICs – will be low priority for funding. NIGMS encourages applications from IDeA-eligible states, HBCUs, and Tribal Colleges and Universities (TCUs), as defined under 25 U.S.C. 1603 (24).  

NIGMS Prioritizes:  

Research Experience programs focused on a single career stage that:  

• Prepare cohorts of individuals to transition into and complete biomedical Ph.D. or M.D./Ph.D. programs, specifically: 
  • Summer undergraduate.  
  • Yearlong postbaccalaureate. 
  • Research-based master’s programs with clear and strong transition plans, typically to distinct institutions.   
• Increase understanding of biomedical research and encourage awareness of and interest in biomedical careers among high school students.  

Mentoring Activities & Networks to: 

• Equip cohorts of NIGMS-supported career awardees with the networks and professional skills to successfully transition to independent research careers. Awards should focus on a single career stage: predoctoral-to-postdoctoral (F99/K00), postdoctoral-to-faculty (K99/R00), or supporting postdoctoral/early career clinician scientists to research independence. NIGMS prioritizes cooperative agreements for mentoring activities and networks for NIGMS-funded career awardees.  
• Address critical workforce needs as part of a formal mentoring structure.  

Courses for Skills Development, Curriculum or Methods Development 

• Courses to equip participants with technical, operational, or professional skills required for careers in the biomedical research workforce.   
• Programs that develop and disseminate innovative curricular or instructional approaches to improve biomedical research education at multiple secondary or postsecondary organizations. 

NIGMS prioritizes funding: 

• Research Experience applications during October council. 
• Courses for Skills Development, Curriculum or Methods development applications during January council. 
• Mentoring Activities & Networks applications during May council.  

• Undergraduate
• Predoctoral
• Postdoctoral/Residency
• Early Career
• Established Investigator
• Other

  Participant Type	Research experiences	Mentoring Activities & Networks	Courses for Skills for Development, Curriculum or Methods Development
  High School Student (at least 16-years-old at the time of appointment)	X
  Undergraduate	X	X
  Postbaccalaureate	X
  Master’s Student	X
  Predoctoral		X	X
  Postdoctoral/Residency		X	X
  Early Career		X	X
  Established Investigator		X	X
  Secondary Educator (middle or high school teacher)	X		X

NIGMS typically supports the following types of projects for up to 5 years: 

• Research experiences 
• Mentoring Activities and Networks 
• Courses for Skills Development 
• Curriculum and methods development. 

NIGMS also supports pilot curriculum and methods development projects for shorter periods (up to three years).  

Award budgets must reflect the actual costs of the proposed project.   

NIGMS will consider up to $500,000 direct costs per year for: 

• Research experiences for postbaccalaureate or master’s students 
• Mentoring activities & networks  
• Courses for skills development  
• Curriculum and methods development projects 

NIGMS will consider up to $250,000 direct costs per year: 

• Research experiences for summer undergraduate students, high school students or secondary educators 

For Research Experiences  

Salary support: Depending on the number of participants in the program and the person-months devoted to administration of the program: 

• Total PD(s)/PI(s) (including a combination of multiple PD(s)/PI(s)) is limited to up to a total of 2.0 person-months effort per year.  
• Total salary support for other administrative staff (for example, a program coordinator to assist the PD(s)/PI(s)) is limited to up to 6 person-months.  

Participant Costs: Participants may only receive funding for the period they participate in the program. Remuneration is through salary and wages. There must be an employee-employer relationship between the participant and the institution. Per the cost principles, participant salary must be consistent with institutional salary policies for individuals in similar circumstances regardless of the source of support for the activity. 

Additionally, for postbaccalaureate and research-based master’s participants:  

• Salary, fringe benefits, tuition and fees up to the maximum NIH-permitted annual graduate student support (NRSA level 0 for postdoctoral trainees) are allowable. 

Other program-related expenses: For research-based master’s participants, institutions may request up to a maximum of $12,500/student participant for Other Program-Related Expenses. 

For all Research Education Awards 

Limited program evaluation costs are allowed up to a maximum of 2% of direct costs per year for the 5-year project period. This includes salaries for evaluation consultants, if any. 

• Research Experiences: [email protected] 
• Mentoring Activities & Networks:  [email protected] 
• Courses, Curriculum or Methods Development: [email protected] 

NIGMS supports the development of technologies to address complex and interdisciplinary research questions in i) basic research, ii) clinical areas that impact multiple organs systems and iii) biomedical workforce development/training through educational activities, that may require additional resources.

A. Tools and technologies for toxicity screening of compounds
B. Devices and computational approaches for improved exposure assessment
C. Assays, complex in vitro systems, and computational approaches for predictive toxicology
D. Validation of sensor technologies, including field testing to improved performance characteristics and usability of the sensors
E. Intervention technologies to prevent or reduce exposures to environmental stressors
F. Tools and approaches for expanding environmental health literacy
 

NIGMS Small Business Program
[email protected]

NIGMS Grants Administration Branch
[email protected]