National Institute of Biomedical Imaging and Bioengineering (NIBIB)

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Mission Statement

The NIBIB Mission is to transform, through technology development, our understanding of disease and its prevention, detection, diagnosis, and treatment.  

Interest Areas

General Topics

NIBIB supports technology development in biomedical imaging, bioengineering, and informatics, as well as the next generation of interdisciplinary researchers across the career continuum and small businesses.  This includes, but is not limited to, development of the following:

  • Biomedical imaging technologies to transform our understanding of biological and disease processes for improving diagnostics, image-guided therapies, and human health (reach out to [email protected]):
    • Bio-Electromagnetic Technologies
    • Image-Guided Interventions
    • Magnetic Resonance Imaging
    • Molecular Probes and Imaging Agents
    • Nuclear Medicine
    • Optical Imaging and Spectroscopy
    • Photoacoustic/Optoacoustic Technologies
    • Ultrasound: Diagnostic and Interventional
    • X-ray and Computed Tomography
  • Broadly applicable biomedical technologies based on device engineering and/or biological engineering that directly interface with, monitor, and regulate biological processes and functions of human physiology to enable new paradigms of human health (reach out to [email protected]):
    • Biomolecular, Cellular, and Multicellular Technologies
    • Physiomimetic, Nano, and Molecular Materials
    • Living Materials
    • Medical Devices
    • Medical Simulators
    • Robotics
    • Bionics
    • Manufacturing and Biomanufacturing Tools
    • Screening and High-Throughput Tools, including Microphysiological Systems
  • Technologies for processing and evaluating complex biomedical information to develop solutions to real-world healthcare problems, building toward practical, patient-centered applications (reach out to [email protected]):
    • Artificial Intelligence, Machine Learning, and Deep Learning
    • Digital Health - Mobile Health and Telehealth
    • Biomedical Informatics
    • Point of Care Technologies – Diagnostics
    • Image Processing, Visual Perception, Virtual/Augmented Reality and Display
    • Bioanalytical Sensors

Assistance Listing

Assistance listings are detailed public descriptions of federal programs used across government agencies that provide grants, loans, scholarships, insurance, and other types of assistance awards. They are maintained in the System for Award Management (SAM) and can be used to search for opportunities in Grants.gov.

View NIBIB Assistance Listing Numbers

  • 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health

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Funding Opportunities and Notices

Search for NIBIB’s funding opportunities and notices

Additional Information by Funding Category

Administrative Supplements
In addition to our Administrative Supplements overview, consider the following NIBIB-specific information.
Administrative Supplement Interest Areas:

NIBIB has limited funds to support Administrative Supplements for unforeseen circumstances. 

Reach out to the grants management and program officials named on the parent grant Notice of Award to discuss the impact of unforeseen circumstances and possible funding options available.

Administrative Supplement Due Dates:

NIBIB accepts and reviews administrative supplement applications on a continuous basis between October 1 and May 31 of each fiscal year. Applications received after May 31 will be considered in either the same or the next fiscal year.

Administrative Supplement Contact:

NIBIB Administrative Supplements Points-of-Contact:

[email protected] 

 

Small Business
In addition to our Small Business overview, consider the following NIBIB-specific information.
Small Business Interest Areas:

The NIBIB Small Business Program aims to translate cutting edge technologies into commercial products to address critical healthcare challenges. Through grants and contracts, the program supports the development of innovative biomedical technologies that improve human health. Areas of interest span biomedical imaging, medical devices, health informatics, diagnostic and therapeutic technologies, and related innovations at the intersection of biology and engineering. Projects should demonstrate strong commercial potential while addressing significant unmet clinical needs in biomedical imaging and bioengineering.

Specific program guidance includes:

  • Technologies may be demonstrated using a specific indication or model system, but the core innovation must be broadly applicable without significant reengineering. 
  • Applications fall outside NIBIB's mission if the primary focus is
    • developing technologies to elucidate basic biological functions or disease mechanisms, or
    • applying and testing previously developed tools or technologies.
  • Per NOT-EB-21-005, NIBIB only supports early-stage clinical trials, i.e., feasibility, Phase I, first-in-human, safety, or other small clinical trials, that inform technology development. NIBIB will not support applications with efficacy, effectiveness, or a post-market concern as an outcome.
  • NIBIB may modify or decline funding applications for budgetary, administrative, or programmatic reasons. This includes reducing budgets, shortening award periods, or choosing not to fund applications.
  • Awardees are strongly encouraged to contact NIBIB's Small Business Team about the Concept to Clinic: Commercializing Innovation (C3i) Program, a mentored, entrepreneurial training course that provides innovators with essential business tools to assess the commercial viability and potential business opportunity for their product.
Phase IIB & Commercialization Readiness Pilot (CRP):
  • NIBIB accepts Commercialization Readiness Pilot (CRP) projects
Clinical Trials:
  • NIBIB accepts clinical trials through the SBIR programs
  • NIBIB accepts clinical trials through the STTR programs
Centers Contact:

NIBIB Small Business Team

[email protected]
 

See Also

National Institute of Biomedical Imaging and Bioengineering (NIBIB)

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