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National Institute on Alcohol Abuse and Alcoholism (NIAAA)
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Mission Statement
The NIAAA Mission is to generate and disseminate fundamental knowledge about the adverse effects of alcohol on health and well-being, and apply that knowledge to improve diagnosis, prevention, and treatment of alcohol-related problems, including alcohol use disorder, across the lifespan.
Interest Areas
General Topics
The following areas represent the core research priorities and general interest areas of the NIAAA:
- Biological Mechanisms and Consequences: Investigating the fundamental neurobiological, genetic, and physiological pathways through which alcohol affects brain function and organ systems.
- Epidemiology and Public Health Impact: Identifying patterns and trends in alcohol use to understand the societal and health-related consequences of misuse across diverse populations.
- Prevention Strategies: Developing and evaluating evidence-based interventions to prevent alcohol misuse and underage drinking, with a focus on risk and resilience factors.
- Diagnosis and Assessment: Improving the accuracy of screening tools and diagnostic criteria for Alcohol Use Disorder (AUD), Fetal Alcohol Spectrum Disorders (FASD), and alcohol-associated organ damage.
- Treatment and Recovery: Advancing behavioral therapies, pharmacotherapies, and innovative technologies to improve treatment outcomes and support long-term recovery.
- Cross-Cutting Themes: Improving alcohol health outcomes by utilizing data science and multi-omics techniques, addressing the impact of alcohol use at different life stages and in women, and encouraging a whole-personal health approach.
Assistance Listing
Assistance listings are detailed public descriptions of federal programs used across government agencies that provide grants, loans, scholarships, insurance, and other types of assistance awards. They are maintained in the System for Award Management (SAM) and can be used to search for opportunities in Grants.gov.
View NIAAA Assistance Listing Numbers
- 93.273 - Alcohol Research Programs
Highlighted Topics
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Funding Opportunities and Notices
Search for NIAAA’s funding opportunities and notices
- NIAAA Grant Funding Opportunity Participation
- NIAAA Notices in the NIH Guide for Grants and Contracts
ICO Funding Policies and Considerations
Visit NIH Fiscal Policies for NIH-wide information on appropriations and other budgetary information (salary limits, stipends, tuition/fees) and Funding Decisions to learn about NIH's consistent and unified approach for making funding decisions.
NIAAA Funding Policies and Considerations builds on that general information.
Additional Information by Funding Category
Administrative Supplements
IMPORTANT REMINDER: Project Summary/Abstract of your application must include a brief description of the supplement’s purpose and scope. Applications without this information in the Project Summary/Abstract will be rejected.
Other considerations
- Administrative supplement requests that exceed $100,000 AND more than 25% of the direct costs of the active year of the parent grant will undergo a second level of review and recommendation of approval/disapproval by the NIAAA National Advisory Council and the NIAAA Director. Grantees should expect a longer review time for these requests
- The parent grant must be active for at least another 12 months at the time of submission
NIAAA will receive administrative supplement applications on a rolling basis. Funding considerations will occur only twice a year: January 31, July 15. Applications received after July 15 will be considered for funding in the next fiscal year.
Grants Management Branch, NIAAA
[email protected]
Office of Extramural Activities, NIAAA
[email protected]
Small Business
NIAAA-specific SBIR and STTR interests are tailored toward commercializing technologies that address the unique physiological, social, and clinical challenges of alcohol misuse.
The NIAAA specifically encourages small business applications in the following high-priority areas:
- Biosensors and Wearables: Developing non-invasive, wearable devices for real-time alcohol monitoring (e.g., transdermal sensors) that provide more accurate data than self-reporting for research and clinical use.
- Digital Health and Telehealth: Creating mobile applications, AI-driven platforms, and software for the remote delivery of evidence-based treatments, such as Cognitive Behavioral Therapy (CBT) or recovery support services.
- Pharmacotherapy Development: Advancing the discovery and testing of new medications to treat Alcohol Use Disorder (AUD), specifically focusing on those with commercial potential and lower side-effect profiles.
- Diagnostic Tools and Biomarkers: Innovating point-of-care diagnostic tests and biological markers for early detection of alcohol-induced organ damage (liver, brain, heart) and Fetal Alcohol Spectrum Disorders (FASD).
- Advanced Data Analytics: Utilizing machine learning and big data tools to analyze large health datasets to predict relapse, identify high-risk drinking patterns, or personalize treatment plans.
- Regulatory Support: Utilizing the Commercialization Readiness Pilot (CRP) to fund late-stage R&D, such as IND-enabling studies, manufacturing scale-up, or clinical trial verification required for FDA clearance.
- Behavioral Interventions: Developing interactive or gamified tools designed to improve treatment adherence, reduce stigma, or provide prevention education in school or workplace settings.
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