National Institute on Drug Abuse (NIDA)
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Mission Statement
The NIDA Mission is to advance science on drug use and addiction and to apply that knowledge to improve individual and public health.
Interest Areas
General Topics
- Characterize properties of emerging drugs/drug combinations and their targets in the brain and periphery
- Develop new approaches to identify emerging drugs; improve the timeliness of data on drug use, substance use disorder (SUD), overdose and other outcomes; understand drivers of overdose mortality trends
- Examine factors influencing risk/resilience for substance use and SUD and translate this knowledge into prevention interventions
- Understand mechanisms of SUD, recovery, and relapse to identify new targets for intervention
- Identify trajectories from drug use to SUD to inform personalized interventions
- Advance research on neuroplasticity towards interventions for SUD and its consequences
- Advance research on neurobiological overlap between pain and SUD to inform interventions
- Develop strategies to minimize opioid use disorder (OUD) risk in the context of pain treatment and improve care for people with OUD and chronic pain
- Advance solutions to disparities in SUD risk, outcomes, and access to care among hard-to-reach and rural populations
- Develop SUD and overdose prevention, treatment, and recovery interventions, and strategies to integrate care across SUD settings
- Advance patient-centered endpoints for clinical trials, including reduction in craving and other SUD symptoms
- Use data science and AI to develop clinical decision support tools and identify gaps in healthcare services for SUD and overdose
- Advance polysubstance use research and treatment for concurrent SUDs
- Develop new approaches to reduce overdose risk
- Evaluate recovery support services and models for delivering these services
- Advance research on co-occurring SUD and mental health disorders, including on co-treatment models
- Advance research on SUD and HIV, including on how drug use affects HIV transmission/progression and related interventions
- Advance the training of a multidisciplinary new generation of scientists
Assistance Listing
Assistance listings are detailed public descriptions of federal programs used across government agencies that provide grants, loans, scholarships, insurance, and other types of assistance awards. They are maintained in the System for Award Management (SAM) and can be used to search for opportunities in Grants.gov.
View NIDA Assistance Listing Numbers
- 93.279 - Drug Use and Addiction Research Programs
- 93.3RP - Research Infrastructure Programs - Research Projects
- 93.675 - Vision Research - Research Centers
- 93.678 - Family Smoking Prevention and Tobacco Control Act Regulatory Research
- 93.HL1 - National Heart, Lung, and Blood Institute - Construction
- 93.HL2 - National Heart, Lung, and Blood Institute - Research Projects
- 93.HL3 - National Heart, Lung, and Blood Institute - Small Business
- 93.HL4 - National Heart, Lung, and Blood Institute - Training/Individual
- 93.HL5 - National Heart, Lung, and Blood Institute - Other Research
- 93.NR6 - Nursing Research - Other Research
Highlighted Topics
| Title | Lead ICO | Participating ICOs | Posted Date | Expiration Date |
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Funding Opportunities and Notices
Search for NIDA’s funding opportunities and notices
ICO Funding Policies and Considerations
Visit NIH Fiscal Policies for NIH-wide information on appropriations and other budgetary information (salary limits, stipends, tuition/fees) and Funding Decisions to learn about NIH's consistent and unified approach for making funding decisions.
NIDA Funding Policies and Considerations builds on that general information.
Additional Information by Funding Category
Administrative Supplements
- NIDA recommends interested applicants reach out to their current program officer as listed on the Notice of Award for the most recent parent award to discuss whether a supplement request would be appropriate
- Administrative supplement requests above $99,999 in direct costs will be reviewed by the National Advisory Council on Drug Abuse.
NIDA accepts administrative supplement requests on a continuous basis but will consider them for funding four times a year; December, February, May and August. The final submission date for each fiscal year is July 1.
Chief Grants Management Officer
National Institute of Drug Abuse (NIDA)
Email: [email protected]
Conferences and Meetings
- With few exceptions, NIDA funding for conference grants is usually ~ $10,000.
- For applications requesting more than one year, the need for multiple years should be justified, e.g., the field develops rapidly enough to justify annual meetings or provide different areas of focus in future years.
NIDA Receipt and Referral Officer
[email protected]
Individual Career Development
- NIDA supports Individual Career Development Awards in all areas of research described in NIDAs current strategic plan.
- Prospective applicants are highly encouraged to contact a NIDA Program Official in their area of interest, prior to preparing an application by contacting [email protected].
- Salary Support: Up to $100,000 plus fringe benefits per year.
- Research Support: Up to $50,000 per year.
Office of Research Training and Career Development
National Institute on Drug Abuse (NIDA)
Email: [email protected]
Individual Fellowship
- NIDA participates in all Ruth L. Kirschstein National Research Service Award (NRSA) Fellowships and the Predoctoral to Postdoctoral Transition Award.
- NIDA supports fellowships in all areas of research described in NIDAs current strategic plan.
- Prospective applicants are highly encouraged to contact a NIDA Program Official in their area of interest, prior to preparing an application by contacting [email protected].
Office of Research Training and Career Development
National Institute on Drug Abuse (NIDA)
Email: [email protected]
Institutional Career Development
- NIDA supports Institutional Career Development Awards in all areas of research described in NIDAs current strategic plan.
- Institutional training for clinician scholars is encouraged.
- Prospective applicants are highly encouraged to contact a NIDA Program Official in their area of interest, prior to preparing an application by contacting [email protected].
- Salary Support: Up to $100,000 plus fringe benefits per year.
- Research Support: Up to $50,000 per year
Office of Research Training and Career Development
National Institute on Drug Abuse (NIDA)
Email: [email protected]
Institutional Training
- NIDA supports Institutional Training in all areas of research described in NIDAs current strategic plan.
- Prospective applicants are highly encouraged to contact a NIDA Program Official in their area of interest, prior to preparing an application by contacting [email protected].
- NIDA accepts T32 applications during every receipt date but funding decisions are made annually each spring for a July 1 start date.
- NIDA supports travel costs up to $2000 per trainee per year
Office of Research Training and Career Development
National Institute on Drug Abuse (NIDA)
Email: [email protected]
Research Education
NIDA supported research education areas include, but are not limited to, the topics below:
- Summer Research Experiences: Supports institutions that provide high-quality research experiences for high school and college students and for science teachers during the summer academic break; summer research experiences must be in scientific research fields relevant to NIDA’s mission.
- Clinical Research Experiences: Supports research education activities for clinicians, clinicians in training, and clinical researchers that enhance the knowledge of substance use- and substance use disorder (SUD)-related research and provide opportunities for active participation in related research.
- Research Education for Health Professionals: Supports programs designed to engage practicing health care professionals in education about current and emerging knowledge derived from scientific research on the neurobiology, epidemiology, prevention, and/or treatment of substance use disorders and related health conditions and provide strategies that can be applied during interactions with patients.
- Courses, Curriculum and Methods: Supports programs that focus on one or more of the following: short courses for skill development, curriculum and methods for data science and other topics aligned with the NIDA mission
- Public Health: Supports mentored substance use research training partnerships that embed public health trainees and early career public investigators within state and local health departments to conduct NIDA mission-relevant research and build the public health substance use research workforce.
- Mentoring Activities: Supports programs focused on mentoring activities designed to enhance mentoring skills and prepare participants for NIDA mission-relevant careers in addiction science.
- Other Research Education: Any other research education program that is aligned with NIDA’s mission can also be considered.
- Undergraduate
- Predoctoral
- Postdoctoral/Residency
- Early Career
- Established Investigator
- Other
- High School
- Clinicians and Clinical researchers
- Medical/nursing/dental/pharmacy/other health profession students
Office of Research Training and Career Development
National Institute on Drug Abuse (NIDA)
Email: [email protected]
Small Business
Consistent with NIH and Presidential priorities, the NIDA Small Business Program supports research and development of innovative medical and non-medical products and services for substance use disorders (SUDs) and adverse health consequences related to non-disordered drug use. Proposed solutions should improve access, affordability, and coordinated care across prevention, diagnosis, treatment, and recovery. NIDA prioritizes scalable solutions deployable within integrated delivery networks across healthcare, criminal justice, workforce, education, housing, and social service systems. Specific areas include, but are not limited to:
- Novel, mechanism-based treatments addressing the evolving overdose crisis (e.g., synthetic opioids, stimulants, polysubstance use)
- Best-in-class opioid use disorder treatments that improve retention and outcomes for individuals not adequately served by existing medications
- Innovative smoking cessation therapies that enhance adherence and long-term effectiveness
- First-in-class pharmacotherapeutics and medical devices for stimulant and cannabis use disorders
- Diagnostic tools for detection and quantification of drug exposure
- Medical devices, including digital diagnostics and therapeutics, and clinical decision support systems supporting SUDs and comorbid mental health conditions, with particular attention to pediatric populations.
- Digital health technologies addressing health-related social needs
- Human-biology-based new approach methodologies and other commercial research tools
- Forensic testing technologies identifying emerging drugs
- FDA Drug Development Tools and Medical Device Development Tools
NIDA strongly encourages applications that include early FDA engagement, consideration of regulatory pathways, payer engagement strategies, real-world evidence generation, and plans for sustainable adoption within integrated delivery networks and value-based care models.
A. Drug Discovery and Development for SUD and medical consequences of drug use.
- Early discovery activities may range from target identification and validation through lead optimization to development of candidates.
- Assay development and validation.
- Preclinical and/or clinical drug development.
- New drug discovery and development-enabling technologies and tools, including Drug Development Tools (DDT), as defined by the FDA.
B. FDA-regulated Medical Devices for SUD and medical consequences of drug use.
- New device development-enabling technologies and tools, including Medical Device Development Tools (MDDT), as defined by the FDA.
- Preclinical and clinical medical devices, including Software as Medical Device (SaMD).
Office of Translational Initiatives and Program Innovations (OTIPI)
[email protected]
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