National Institute of Dental and Craniofacial Research (NIDCR)

Mission Statement

The NIDCR Mission is to advance fundamental knowledge about dental, oral, and craniofacial (DOC) health and disease and translate these findings into prevention, early detection, and treatment strategies that improve overall health for all individuals and communities across the lifespan.


Interest Areas

General Topics

The NIDCR Extramural Research Programs plan, develop, and manage basic, translational, and clinical research in dental, oral, and craniofacial (DOC) health and disease through grants and cooperative agreements. NIDCR is committed to nurturing and strengthening a robust research workforce. The goal is to facilitate the most promising discoveries and emerging technologies for rapid translation to clinical applications for improving the health of all people across their lifespan. Scientific areas of interest:

• Orofacial pain conditions and neuroscience including temporomandibular joint and muscle disorders
• Odontogenic diseases
• Oral microbiome and polymicrobial diseases involving bacterial, fungal, and viral communities
• Oral mucosa and cancer biology of the oral cavity, pharynx, and salivary glands
• DOC developmental biology and congenital anomalies 
• DOC computational biology and data science approaches for prevention, diagnostics and therapies 
• Dental repair, restoration, and clinical technologies
• DOC regenerative medicine 
• Immunomodulatory oral science examining host–immune interactions including periodontal disease
• DOC precision medicine applying genetics, multi-omics, and data science to DOC biology
• DOC biomedical clinical trials addressing prevention, diagnosis, or treatment 
• DOC patient health and epidemiology including population-based studies
• Oral and systemic health integration and shared disease mechanisms
• Salivary gland biology and rheumatic disease
• DOC behavioral interventions and assessment methodologies
• Behavioral and biomedical processes influencing DOC and systemic health outcomes
• DOC health disparities across populations and settings
• Implementation science to improve HIV/AIDS–related oral health outcomes

Assistance Listing

Assistance listings are detailed public descriptions of federal programs used across government agencies that provide grants, loans, scholarships, insurance, and other types of assistance awards. They are maintained in the System for Award Management (SAM) and can be used to search for opportunities in Grants.gov.

View NIDCR Assistance Listing Numbers

  • 93.121 - Oral Diseases and Disorders Research

Highlighted Topics

Title Lead ICO Participating ICOs Posted Date Expiration Date

Funding Opportunities and Notices

Search for NIDCR’s funding opportunities and notices


ICO Funding Policies and Considerations

Visit NIH Fiscal Policies for NIH-wide information on appropriations and other budgetary information (salary limits, stipends, tuition/fees) and Funding Decisions to learn about NIH's consistent and unified approach for making funding decisions.

NIDCR Funding Policies and Considerations builds on that general information.


Additional Information by Funding Category

Administrative Supplements
In addition to our Administrative Supplements overview, consider the following NIDCR-specific information.
Administrative Supplement Interest Areas:

Only in certain circumstances, NIDCR may consider providing administrative supplements to existing awards. Applicants are encouraged to contact an NIDCR Program Officer prior to submission. 

Administrative Supplement Due Dates:

Any administrative supplement submitted to NIDCR must be received no later than July 1 to be considered for funding in that fiscal year.

Administrative Supplement Contact:

For questions regarding administrative supplements, please contact your NIDCR Program Officer or email [email protected] and include "Administrative supplement" in the subject line.

Conferences and Meetings
In addition to our Conferences and Meetings overview, consider the following NIDCR-specific information.
Conferences and Meetings Interest Areas:

The National Institute of Dental and Craniofacial Research (NIDCR) supports scientific conferences, including symposia, seminars, and workshops, that align with its mission to improve dental, oral, and craniofacial (DOC) health. Eligibility is limited to domestic institutions and organizations, including established scientific and professional societies. 

NIDCR prioritizes applications for meetings that:

  • Are open to the broader scientific community
  • Represent emerging areas of DOC research
  • Highlight innovative approaches to achieving research objectives
  • Engage early-career investigators, students, and postdoctoral fellows
  • Provide dedicated travel support to facilitate participation of early-career scientists

Applications will generally not be considered for support if they primarily propose clinical training without a substantive research focus, limit attendance to a restricted audience, or address topics outside the mission and programmatic interests of NIDCR.

Conferences and Meetings Budget Considerations:

Primary support of conferences is limited to a maximum of $30,000 per meeting, but the actual award will be contingent upon availability of funds and programmatic priorities. Secondary support of a conference is usually limited to $3,000 and may be requested if another institute or center (IC) at NIH has agreed to provide primary support. NIDCR will serve as secondary IC on such applications.

Conferences and Meetings Key Date Considerations:

NIDCR follows standard R13 receipt dates.
 

Conferences and Meetings Project Period Considerations:

NIDCR supports applications for up to 5 years of support for a series of recurring meetings.

  • NIDCR provides support on a year-by-year basis; future years are not guaranteed.
  • Each year of a recurring meeting is reviewed and considered independently.
  • Funding decisions are based on alignment with NIDCR mission and current program priorities.
Conferences and Meetings Contacts:

NIDCR Program Staff

[email protected]

Individual Career Development
In addition to our Individual Career Development, consider the following NIDCR-specific information.
Individual Career Development Interest Areas:

NIDCR supports mentored research training and career development of individuals with research or clinical doctoral degrees proposing basic, behavioral, translational and/or patient oriented research, analysis and discoveries that advance dental, oral and craniofacial health. 

  • Research Scientist Development Award (K01) 
  • Clinical Scientist Research Career Development Award (K08) 
  • Patient-Oriented Research Career Development Award (K23) 
  • Quantitative Research Career Development Award (K25) 
  • NIH Parent and NIDCR Dual Degree Dentist Scientist Pathway to Independence (K99/R00) 
  • Independent Scientist Award (K02) 

NIDCR prioritizes funding for postdoctoral fellows, non-tenured early career faculty and clinician scientists. For K08 & K23 programs, dentists may use the award to pursue graduate research training that results in a PhD or equivalent doctoral degree. For the Independent Scientist Award (K02), NIDCR supports recent independent scientists with active NIDCR R01 or equivalent research project grant as Principal Investigator (PI) by providing protected time to focus on their research careers.  

Individual Career Development Project Period Considerations:
NIDCR may limit project periods as follows:

NIDCR limits project periods as follows:

  • 2-5 years for K02
  • 3-5 years for K01, K08, K23 and K25
  • 1-2 years for K99
  • For the R00 phase:
    • Up to 3 years under NIH parent announcement and 5 years under NIDCR Dual Degree Dentist Scientist Pathway to Independence for awardees who secure a U.S dental school faculty position with concurrent enrollment in a clinical dental specialty program.   
Individual Career Development Salary Fringe Benefits:
  • NIDCR will support up to $100,000 in salary plus fringe benefits per year.
Individual Career Development Other Program Related Expenses:

NIDCR will provide research support at the following levels:

  • $25,000 per year for K01, K08, K23, K25 and K99
  • $15,000 per year for K02
Individual Career Development Research Effort Considerations:
  • NIDCR expects candidates to commit a minimum of 75% full-time professional effort to their program of career development.​
  • NIDCR will allow surgeon scientists with active surgical duties and those pursuing surgical specialty training during the K award to devote a minimum of 50% full-time professional effort to research and career development activities associated with the K award.
Individual Career Development Contacts:

Research Training & Career Development Branch
[email protected]

Individual Fellowship
In addition to our Individual Fellowships Overview, consider the following NIDCR-specific information.
Individual Fellowships Interest Areas:
  • NIDCR funds predoctoral and postdoctoral fellowships, participating in all parent Ruth L. Kirschstein National Research Service Award (NRSA) Fellowships, and the INCLUDE Predoctoral to Postdoctoral Transition Award (F99/K00).
  • NIDCR also funds Individual Senior Fellowships (e.g., F33).
Individual Fellowships Project Period Considerations:
NIDCR may limit project periods for specific education activities, as follows:
  • INCLUDE Pre to Postdoctoral Transition Award (F99/K00)
    • F99 Predoctoral: Minimum of one year and up to two years
    • K00 Postdoctoral: Up to four years
  • Individual Predoctoral NRSA for M.D./Ph.D. Fellowships (F30)
    • Maximum of 6 years of support
Individual Fellowships Budget Considerations:
In addition to current NRSA stipends, tuition/fees, and other budgetary levels, NIDCR may apply the following limits to applicable awards:
  • INCLUDE F99 Predoctoral
    • Institutional allowance: NRSA levels, Tuition: NRSA levels + $1500 meeting for the 1st year 
  • INCLUDE K00 Postdoctoral
    • Salary: up to $75000; up to $3000/year for research development; $1500 meeting for the 1st year; Tuition: not allowed, but research support could be used to cover eligible short term courses or training
  • Predoctoral Individual National Research Service Award (F31)
    • Institutional allowance: NRSA levels + $800 meeting
  • Individual Predoctoral NRSA for M.D./Ph.D. Fellowships (F30)
    •  Institutional allowance: NRSA levels + $800 meeting
  • Postdoctoral Individual National Research Service Award (F32)
    • Institutional allowance: NRSA levels + $800 meeting
Individual Fellowships Contacts:

Research Training & Career Development Branch
[email protected]

Institutional Training
In addition to our Institutional Training, consider the following NIDCR-specific information.
Institutional Training Interest Areas:

NIDCR encourages institutions to develop innovative and novel research training opportunities that enhance the research workforce pipeline dedicated to improving dental, oral and craniofacial health (DOC). NIDCR prioritizes training programs with a robust curriculum of study, programmatic activities and research experiences that will facilitate development toward independent research careers in DOC research areas.

Institutional Training Participants:
NIDCR prioritizes funding for the following trainees:
  • Predoctoral Ph.D., and dual degree D.D.S./D.M.D. and Ph.D. degree 
  • Postdoctoral training for dentists leading to Ph.D. or equivalent research degree, or master’s in clinical research or public health
  • Postdoctoral training for dentists or individuals with other clinical doctoral degrees, and for non-clinician Ph.D. scientists

NIDCR will fund a maximum of 10 trainee slots per T32 training grant

Institutional Training Project Period Considerations:
NIDCR may limit project periods as follows:
  • Support for up to five years
Institutional Training Budget Considerations:
  • NIDCR supports travel costs up to $800 per full time trainee per year.
Institutional Training Contacts:

Research Training & Career Development Branch
[email protected]

Research Education
In addition to our Research Education overview, consider the following NIDCR-specific information.
Research Education Interest Areas:
  • NIDCR supports institutions that provide high-quality research experiences for high school and college students and for science teachers during the summer academic break; summer research experiences must be in priority scientific, health-related research fields relevant to the NIDCR mission.
  • NIDCR encourages data intensive projects focused on developing, disseminating, and using data and data science resources, methods, and tools for dental, oral, and craniofacial (DOC) research.  
  • NIDCR expects these projects to maximally integrate and reuse research, health, and clinical data for knowledge discovery and translation.  
Research Education Key Date Considerations:

NIDCR only considers Research Education applications during October council.​

Research Education Participants:
NIDCR prioritizes funding for participants in the following areas:
  • Undergraduate
Research Education Project Period Considerations:
NIDCR may limit project periods for specific education activities, as follows:

NIDCR supports a minimum of 8 weeks and a maximum of 15 weeks of research education experience each year for participants.

Research Education Budget Considerations:
NIDCR may limit budgets for specific education activities, as follows:

NIDCR will consider summer research educational experience programs up to $125,000 in direct costs per year.

Research Education Personnel, Participant, and Other Program-Related Costs:
NIDCR may limit awarded budgets for personnel, participant, and other costs, as follows:
  • Up to $50,000 combined salary, administrative, clerical or other staff with responsibilities directly associated with designing, directing and administering the research experience program.  
  • Participant costs generally include salary and fringe benefits for high school and undergraduate students consistent with institutional salary policies. Up to $21,000 for 15 weeks for a science teacher, and prorated if shorter.  
  • Other program-related expenses support may be considered to defray the cost of housing, registration fees or tuition, consultant costs, equipment, supplies, travel for key persons, and other program-related expenses.
Research Education Funding Instruments:
NIDCR does not award Research Education Cooperative Agreements (UE5)
NIDCR awards Research Education Grant Projects (R25)
Research Education Contacts:

Research Training & Career Development Branch
[email protected]

Small Business
In addition to our Small Business overview, consider the following NIDCR-specific information.
Small Business Interest Areas:

NIDCR supports small business–led development of technologies and products that translate dental, oral, and craniofacial (DOC) research into clinically actionable solutions across the lifespan. Emphasis is on feasibility, validation, regulatory readiness, and commercialization. Projects should align with NIDCR’s goal to rapidly translate oral health innovations toward clinical impact. Early engagement with program staff is encouraged to ensure alignment with mission and priorities. Scientific areas of interest include: 

  • Targeted DOC diagnostics and therapeutic platforms for tooth-related diseases and periodontal/peri-implant conditions
  • Orofacial pain assessment and management technologies, including clinical decision support
  • Oral microbiome-based diagnostics and therapeutic platforms for polymicrobial diseases
  • AI/ML-enabled predictive health and clinical decision support tools for DOC care
  • Advanced dental materials, restorative technologies, and digital manufacturing systems
  • Regenerative medicine technologies for craniofacial and dental tissue reconstruction
  • Immunomodulatory and precision therapeutic delivery systems for oral and craniofacial conditions
  • Digital behavioral and monitoring tools targeting DOC outcomes
  • Real-world evidence and patient outcome data platforms to support clinical adoption, evidence generation, and downstream coverage considerations
  • Implementation and dissemination technologies for priority-population oral health interventions
  • Integrated oral–systemic health assessment and intervention platforms
  • Regulatory and commercialization readiness tooling to support evidence generation, usability, and market adoption
Phase IIB & Commercialization Readiness Pilot (CRP):
NIDCR does not accept Phase IIB SBIR projects
NIDCR accepts Commercialization Readiness Pilot (CRP) projects
Clinical Trials:
NIDCR does not accept clinical trials through the SBIR programs
NIDCR does not accept clinical trials through the STTR programs
NIDCR does not accept clinical trials through the Phase IIB SBIR program
NIDCR does not accept clinical trials through the Commercialization Readiness Pilot (CRP)
Small Business Contact:

Small Business Program

[email protected]


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