Mentored Quantitative Research Development Award (Parent K25 - Independent Clinical Trial Not Allowed) (PA-24-191)

Table of IC-Specific Information, Requirements and Staff Contacts

NIH Institute or Center ContactsInstitute/Center Specific Information
National Cancer Institute (NCI)

Scientific Program Contact:
NCI K25 Program Director
Email:   [email protected]

Grants Management Contact:
NCI Financial Contact
Email: [email protected]
 
NCI Specific Information:

The NCI K25 award is aimed at fostering the research careers of scientists with post-doctorate degree training in quantitative science disciplines, including physics, chemistry, mathematics, statistics, economics, computer science, imaging science, and informatics, or engineering, who have little or no training in the biological or biomedical sciences and are now committed to developing research programs in understanding human biology and human disease as it relates to cancer-focused research. Early-stage investigators and established investigators who wish to incorporate cancer-focused research into their quantitative science or engineering projects or reorient their quantitative science or engineering research interests to cancer-focused research and who have not already obtained research project (i.e., R01 or equivalent) grant support for biological or biomedical projects, are eligible for this award.

Individuals with less than three years of post-doctorate degree training experience in quantitative sciences or engineering should consider the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32) (https://www.cancer.gov/grants-training/training/funding/f32) instead.

NCI requires that the K25 applicant identify a mentor whose research is cancer focused.

Salary Support: Up to $100,000 plus fringe benefits per year.
Research Support: Up to $50,000 per year.

National Eye Institute (NEI)

 

 

 

Scientific Program Contact:Email: [email protected]

 

Grants Management Contact:
Email: [email protected]

 

 

NEI Specific Information:

NEI will accept applications for funding that are responsive to programmatic priority areas for research within vision and ophthalmology as detailed in the (NEI Strategic Plan: Vision for the Future (PDF 22.5 MB).

NEI utilizes the K25 program to attract and support research-oriented investigators with quantitative science and engineering backgrounds but without experience in biomedical research who wish to focus on and apply their skills to areas supported by NEI. 


NEI has a 6-year limit of cumulative support on institutional (K12, KL2) and individual mentored K awards (K01, K08, K23, K25).


Salary Support: Up to the legislative cap plus fringe benefits per year. 
Research Support: Up to $25,000 per year but with sufficient justification can request up to $50,000 per year.

National Heart, Lung, and Blood Institute (NHLBI)

For Scientific Program and Grants Management Inquiries, Contact:

Email: [email protected]
 

NHLBI Specific Information:

Please refer to for specific information on NHLBI programs and career development policies.

NHLBI has a 6-year limit of cumulative support on institutional and mentored Ks (e.g., K12 or KL2 plus the K25).

NHLBI encourages career development award applications from quantitative scientists that propose mentored training to establish expertise in data science, including but not limited to Artificial Intelligence, Machine Learning, Deep Learning, Healthcare Data Analytics, Public Health Data Analytics, Imaging Analytics, Predictive Analytics, and Bioinformatics, or propose training to complement existing data science expertise with relevant biomedical/clinical knowledge for the creation, management, analysis, and integration of complex, large data sets in support of data-driven discovery in heart, lung, blood, and sleep health and disease. Proposals must meet all other requirements specified in the parent announcement.

Salary Support: Up to $100,000 plus fringe benefits per year.
Research Support: Up to $40,000 per year.
National Institute on Aging (NIA)

Scientific Program Contact:
Email: [email protected]

Grants Management Contact:
Email: [email protected]
 
NIA Specific Information:

See: https://www.nia.nih.gov/research/training/k25-mentored-quantitative-research-career-development-awards

Salary Support: Up to 75,000 plus fringe benefits per year.
Research Support: Up to $40,000 per year.
 
National Institute on Alcohol Abuse and Alcoholism (NIAAA) 

Scientific Program Contact: 
Email: [email protected]

Grants Management Contact: 
Email: [email protected]
 

NIAAA Specific Information: 

NIAAA supports faculty level early-stage investigator and new investigator development under this announcement. Applicants are encouraged to refer to the NIAAA Strategic Plan for NIAAA research priorities. Applicants are to comply with the NIH and NIAAA Data Management and Sharing policies, NOT-OD-21-013 and NOT-AA-23-001. Prospective applicants are strongly encouraged to contact the appropriate NIAAA staff contact prior to preparing an application.

  • All applications must include a strong and credible plan for the applicant's transition to research independence, outlining milestones and providing evidence of significant institutional commitment to the development of the K applicant as an independent researcher at the sponsoring institution.
  • Candidates with less than 4 years of post-doctoral research experience, who are enrolled in the T32 training programs are strongly encouraged to apply for a K99/R00 award.
  • At the time of award, the candidate must have a secured full-time faculty or faculty equivalent appointment in an appropriate research-intensive environment.

 

Salary Support: Up to $100,000 plus fringe benefits per year, commensurate with the applicant institution's salary structure for persons of equivalent qualifications, experience, and rank. Institutional Base Salary will be verified at the time of award. 
Research Support: Up to $50,000 per year.

National Institute of Allergy and Infectious Diseases (NIAID)

Scientific Program Contact: 
Email: [email protected]

Grants Management Contact:
Email: [email protected]  
NIAID Specific Information:

NIAID sponsors the K25 program to attract investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease in NIAID mission areas. 

See https://www.niaid.nih.gov/grants-contracts/career-development-awards for more details on NIAID Career Development Awards. 

Salary Support: Up to $100,000 plus fringe benefits per year.
Research Support: Up to $50,000 per year.
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Scientific Program Contact:
Email: [email protected]

Grants Management Contact:
Email: [email protected]  
NIAMS Specific Information:

Information about NIAMS funding mechanisms is available at http://www.niams.nih.gov/Funding/Funding_Opportunities/activity_codes.asp.

Salary Support: Up to $75,000 plus fringe benefits per year.
Research Support: Up to $25,000 per year.
National Institute of Biomedical Imaging and Bioengineering (NIBIB)

Scientific Program Contact:
Email: [email protected]

Grants Management Contact:
Chief Grants Management Officer
Email: [email protected]
NIBIB Specific Information:

NIBIB uses the K25 to support research-oriented quantitative scientists and engineers with little or no experience in medicine and the life sciences to develop relevant research skills needed to become an independent investigator conducting research in scientific program areas relevant to NIBIB. Examples of quantitative scientific and technical backgrounds considered appropriate for this award include, but are not limited to: mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry, and engineering. NIBIB will only support individuals who are within 10 years of the completion of their PhD. The duration of support can be 3 or 4 years. 

Before preparing an application, prospective applicants are encouraged to fill out the NIBIB K25 Eligibility Inquiry Form [PDF] and forward it along with the requested attachments to the Scientific Program Contact in order to verify eligibility, determine if the application is appropriate for a K25 award through NIBIB, and ensure that the application is submitted to the appropriate NOFO. 

More detailed information can be found at https://www.nibib.nih.gov/training-careers/training-opportunities/mentored-quantitative-research-development-award-parent-k25

Salary Support: Up to $90,000 plus fringe benefits per year.
Research Support: Up to $40,000 per year.
 
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Scientific Program Contact:
Email: [email protected]

Grants Management Contact:
Email: [email protected]

NICHD Specific Information:

NICHD offers fellowships, training grants, and career development awards in areas relevant NICHD's mission, including normal and abnormal human development; male and female fertility and infertility; developing and evaluating contraceptive methods; pregnancy and childbirth; prenatal and postnatal development; childhood development and behavior through adolescence; improving the safety and efficacy of pharmaceuticals for use in pregnant women, infants, and children; HIV infection and transmission, AIDS, and associated infections; pediatric growth and endocrine research; developmental biology and typical and atypical development; intellectual and developmental disabilities; reproductive biology and medicine; gynecologic health conditions, including pelvic floor disorders; childhood injury and critical illness; population dynamics; and medical rehabilitation. More detailed information and Program Staff contacts may be found at: https://www.nichd.nih.gov/about/org/der/branches, and for the National Center for Medical Rehabilitation Research at: http://www.nichd.nih.gov/about/org/ncmrr/Pages/overview.aspx.

NICHD has a 6-year limit of cumulative support on institutional K awards (e.g., K12, KL2) and individual mentored K awards (e.g., K01, K08, K23, K25).

Salary Support: Up to $75,000 plus fringe benefits per year.
Research Support: Up to $25,000 per year
 

National Institute on Deafness and Other Communication Disorders (NIDCD)

Scientific Program Contact:
Email: [email protected] 

Grants Management Contact:
Email: [email protected]

 

NIDCD Specific Information: 

NIDCD uses the K25 program to support individuals with quantitative scientific and engineering backgrounds without sustained involvement in biomedical or behavioral research who wish to focus their research in areas supported by NIDCD.

  • Application must demonstrate its contribution to NIDCD and its fit to NIDCD's Mission, Research Priorities, and Strategic Plan.
  • Applicants are strongly encouraged to provide clear evidence that adequate resources are available at the institution for the successful completion of the proposed research project.
  • Applications should include explicit statements from the institution and the mentor(s) addressing the following:
    • Detailed information about who will provide the necessary resources;
    • Funding source and amount of additional funding (as needed);
    • Support staff available and committed to the project;
    • Availability of biostatistical support for the duration of the study - including the planning period; and
    • A contingency plan (for the institution and mentor) for completion of the study in the event the awardee leaves the institution earlier than the end date of the award.


Salary Support: Up to $80,000 plus fringe benefits per year.
Research Support: Up to $30,000 per year.

National Institute of Dental and Craniofacial Research (NIDCR)

Scientific Program Contact:
Email: [email protected]

Grants Management Contact:
Email: [email protected]

NIDCR Specific Information:

NIDCR supports research career development of quantitative scientists who propose mentored research training in applying their expertise in quantitative disciplines, e.g., engineering, physics, chemistry, mathematics, and data science (such as artificial intelligence, machine learning, bioinformatics, and data analytics applied to public health and health data) in addressing basic, clinical or behavioral biomedical research, analysis and discovery to advance dental, oral and craniofacial health.

NIDCR encourages data science-oriented projects focused on developing and using data and data science resources, methods, and tools for dental, oral, and craniofacial (DOC) research.

Salary Support: Up to $100,000 plus fringe benefits per year.
Research Support: Up to $25,000 per year.
 

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Scientific Program Contact:
Division of Diabetes, Endocrinology, and Metabolic Diseases:
Email: [email protected]

Division of Digestive Diseases and Nutrition:
Email: [email protected] 

Division of Kidney, Urologic and Hematologic Diseases:
Email: [email protected]

Office of Obesity Research:
Email: [email protected]

Grants Management Contact:
Email: [email protected]

NIDDK Specific Information:

The purpose of the NIDDK K25 award is to provide an intensive, supervised, research and career development experience for quantitative scientists who would like to transition to independent research careers in biomedical research. NIDDK encourages K25 applications in all areas of research supported by the NIDDK (https://www.niddk.nih.gov/research-funding/research-programs). Information on the NIDDK K25 can be found at https://www.niddk.nih.gov/research-funding/process/apply/funding-mechanisms/k-awards/k25
The NIDDK provides further information on all K-award programs on our training and career development web site: https://www.niddk.nih.gov/research-funding/training-career-development.

Prospective applicants are strongly encouraged to contact NIDDK program staff to discuss relevance of the proposed studies to NIDDK's research interests and appropriateness of the K25 for accomplishing their overall career development goals.

K25 awardees are also strongly encouraged to attend the NIDDK K Awardees' Workshop while supported on the K25 (one-time attendance for this biennial meeting). Up to $1500 will be provided for K25 awardees to attend this meeting (in addition to the above-listed Research Support).

Salary Support: Up to $90,000 plus fringe benefits per year.
Research Support: Up to $40,000 per year.
National Institute on Drug Abuse (NIDA)

Scientific Program Contact:
Office of Research Training and Career Development 
Email: [email protected]

Grants Management Contact:
Chief, Grants Management Officer
Email: [email protected]

NIDA Specific Information:

Please note that the aggregate total of NIH mentored career award support (both institutional and individual) cannot exceed 6 years. A prospective K25 applicant who was appointed to an institutional K12 award must contact NIDA prior to submitting an individual mentored K application to confirm eligibility. Please contact [email protected] for additional details.

Salary Support: Up to $100,000 plus fringe benefits per year.
Research Support: Up to $50,000 per year. Examples include supplies, equipment, technical personnel, travel, and statistical services.

National Institute of Environmental Health Sciences (NIEHS)

Scientific Program Contact:
Email: [email protected]

Grants Management Contact: 
Email: [email protected]
 

NIEHS Specific Information:

The Career Development and Research Plan must be consistent with the research interests of NIEHS.

Applications from data scientists with quantitative backgrounds in computer science, artificial intelligence, bioinformatics, physics, mathematics, statistics, and engineering who are proposing to develop tools and methods for application to environmental health data are encouraged. Ecologic, biomonitoring, biotransformation or biodegradation studies are not considered within the NIEHS mission and are not responsive. Applications from individuals with backgrounds in chemistry or environmental engineering will only be responsive when the degree and previous research are in the physical sciences with a computational emphasis.

For further information on the research interests of the Institute, please see: https://www.niehs.nih.gov/.

Potential applicants are strongly encouraged to contact the program official identified in the contact table before preparing an application to discuss eligibility requirements and the relevance of the proposed research to the Institute's research priorities.

Salary Support: Up to $100,000 plus fringe benefits per year.
Research Support: Up to $40,000 per year.

National Institute of General Medical Sciences (NIGMS)

Scientific Program Contact:
Email: [email protected]

Grants Management Contact:
Email: [email protected]
NIGMS Specific Information:

Potential candidates are encouraged to visit the NIGMS K25 webpage: Mentored Quantitative Research Career Development Awards for Faculty (K25). NIGMS will give high priority to applications directly related to the mission of the institute (https://www.nigms.nih.gov/about-nigms/who-we-are/overview). 



Salary Support: Up to $75,000 plus fringe benefits per year.
Research Support: Up to $40,000 per year.

National Library of Medicine (NLM)

 

Scientific Program Contacts:
Email: [email protected]
 


Grants Management Contact:
Email: [email protected] 

NLM Specific Information: 

NLM supports research career development in clinical/public health informatics, basic bioinformatics, translational bioinformatics, data science, and personal informatics. We define informatics as the intersection of computer, information and behavioral sciences with one or more application domains. Application domains of interest include health care delivery, basic biomedical research, clinical and translational research, public health and others. Whatever the application domain, the research career focus must be informatics or data science. 

Salary Support: Up to $125,000 plus fringe benefits per year. 
Research Support: Up to $50,000 per year. 

Salary level must be commensurate with the applicant institution's salary structure for persons of equivalent qualifications, experience, and rank. For any applicants with no more than 4 years of postdoctoral research, up to $75,000 plus fringe benefits per year would be considered commensurate.

NIH Office of Data Science Strategy (ODSS)

ODSS program contact: 
Training, Workforce Initiative, and Community Engagement Unit 
Email: [email protected]

Office of Data Science Strategy Specific Information:

 

The NIH Office of Data Science Strategy (ODSS) is committed to growing a strong and diverse data science community and ensuring that data science advances in biomedical and health research can benefit all populations. ODSS is interested in supporting Career Development Award projects in data science areas including but not limited to: artificial intelligence, clinical informatics, cloud computing, statistics, computational science, software design and programming, bioinformatics, visualization, machine learning, predictive analytics, supercomputing, modeling and simulation, digital health, data sharing and access, data management, data security and data privacy in human subject's research, and research ethics and integrity. Applications are strongly encouraged from individuals from diverse backgrounds, including from groups that are underrepresented in the biomedical, clinical, behavioral and social sciences, in alignment with the Notice of NIH's Interest in Diversity (NOT-OD-20-031).

Office of Research on Women's Health

Scientific Program Contact: 
Email: [email protected]

ORWH Specific Information:

ORWH focuses on advancing research that is relevant to the health of women and supporting women in biomedical careers. Applicants should ensure their proposed work intersects with the goals, objectives, and guiding principles of the trans-NIH Strategic Plan for Women's Health Research (https://orwh.od.nih.gov/about/trans-nih-strategic-plan-womens-health-research). ORWH does not award grants but co-funds applications and research projects that have received an award from one of the participating NIH Institutes and Centers listed in the announcement. Visit the ORWH website (https://orwh.od.nih.gov/) or contact the appropriate ORWH staff to learn more.


This page last updated on: February 11, 2026
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