How to Apply – Application Guide

Use the application instructions found on this page along with the guidance in the funding opportunity to submit grant applications to NIH, the Centers for Disease Control and Prevention, the Food and Drug Administration, and the Agency for Healthcare Research and Quality.

Policy Quick Links


Form-by-Form, Field-by-Field Application Instructions


Determine the Correct Application Instructions for Your Activity Code
Application Instructions Description SF424 (R&R) - Version H
(Due dates ON/BEFORE Jan. 24, 2025)		 SF424 (R&R) - Version I
(Due dates ON/AFTER Jan. 25, 2025)
G
General Instructions
Comprehensive guidance for research, training, fellowship, career development, multi-project, and small business applications HTML / PDF HTML / PDF
Filtered Application Instructions
R
Research Instructions
Guidance for research only
Activity Codes: Research (R), including Research Education (R25), and equivalent Cooperative Agreements (U)		 PDF PDF
K
Career Development Instructions
Guidance for career development only
Activity Codes: Individual Career Development (K), excluding Institutional Career Development (K12, KL2, KM1)		 PDF PDF
T
Training Instructions
Guidance for training only
Activity Codes: Institutional Training (T), including International Training (D43, D71, U2R) and Institutional Career Development (K12, KL2, KM1)		 PDF PDF
F
Fellowship Instructions
Guidance for fellowship only
Activity codes: Fellowship (F)		 PDF PDF
M
Multi-Project Instructions
Guidance for multi-project only
Activity Codes: Program Project Grants and Center Grants (P) and equivalent Cooperative Agreements (U)		 PDF PDF
B
SBIR/STTR Instructions
Guidance for small business only
Activity Codes: R41-R44, SB1, U43, U44, UB1, UT1, UT2		 PDF PDF

FAQs

Resources

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    General

    Quick Links
    Systems
    • ASSIST—NIH system used to access, prepare, and submit application forms
    • eRA Commons—NIH system used to securely exchange information between agency staff and applicants/recipients
    • Grants.gov—central portal used by all federal grant-making agencies and their applicants to find and apply for federal grant funding

    Videos

      See Also

      • eRA—general information, tutorials, user guides, and other resources for eRA systems
        • eRA News—announcements of system features and system health

      Contact

      Section VII. Agency Contacts in each funding opportunity provides application submission, scientific/research, peer review, and financial/grants management contacts.

      Check online guidance and direct your questions to staff in your organization's sponsored programs office. If you still need assistance, find NIH contacts at Need Help?

      This page last updated on: December 11, 2024
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