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Stephen I. Katz Early Stage Investigator Research Project Grant (PAR-21-038 PAR-21-039)


Purpose of the Award


  • Named in honor of the late National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) Director, Stephen I. Katz, M.D., Ph.D.
  • Supports an innovative project in an area of science that represents a change in research direction for the Principal Investigator and for which no preliminary data exist
  • Principal Investigator must be an early stage investigator (ESI)


  • Must propose a new research direction for the ESI(s)
    • An incremental advancement/expansion/extension of previous research effort not appropriate
    • Appropriate level of departure from previous efforts will be field-dependent
    • Merit and feasibility based on conceptual framework, level of innovation, and potential to significantly advance our knowledge and understanding
  • Peer review
    • Reviewed in standing study sections in the NIH Center for Scientific Review
    • Clustered for discussion during the meeting with other Katz R01 awards
    • Percentiled with and against other R01 applications
  • No specific dollar limit
  • Advance permission required for $500,000 or more (direct costs) in any year
  • May request up to five years of funding
  • Utilized by nearly all NIH Institutes and Centers


  • Preliminary data (data not yet published) not allowed
  • Attachment on “New Research Directions” required

More Information