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High End Instrumentation (HEI) Grant Applications (S10)

Purpose of the Award

  • Encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of expensive, specialized, commercially available instruments or integrated systems that cost at least $600,001.
    • Types of instruments supported include, but are not limited to, X-ray diffraction systems, nuclear magnetic resonance (NMR) and mass spectrometers, DNA and protein sequencers, biosensors, electron and confocal microscopes, cell-sorters, and biomedical imagers.


  • Maximum award is $2,000,000.


  • Reviewers should not evaluate the scientific merit of the research project components, because these have been previously peer reviewed.

More Information

  • Consult the funding opportunity  PAR-21-126 to read the Review and  Selection Process section; Individual funding opportunities often have additional review criteria and/or considerations. See section V of the PAR.
  • NO MPI is allowed. Only one contact PI is allowed.
  • No videos are allowed in the application, as indicated in the PAR.

Last Reviewed on May 19, 2021.