Research Project (R01)
To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies.
Purpose
The Research Project (R01) is NIH's most commonly used grant program for independent research projects.
Special Considerations
- Are you an early stage investigator (ESI)?
- If all the PD/PIs on an R01 (or R01-equivalent) application have ESI status on the date an application is submitted, the application will be flagged as ESI and will receive special consideration during the review and funding process. See Early Stage Investigator (ESI) Policies to learn more.
- The Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project in an area of science that represents a change in research direction for an early stage investigator and for which no preliminary data exist.
- Do you provide peer review service?
- An alternative submission policy is available for R01, R21, and R34 grant applications where one or more of the designated PD/PIs serve as an appointed member of an NIH chartered standing study section, NIH Board of Scientific Counselors, NIH Advisory Board or Council, or an NIH Program Advisory Committee. This policy allows applications to be submitted on a continuous basis, peer reviewed in a timely manner, and assigned to an Advisory Council per designated council round deadlines. See Continuous Submission to learn more.
Award Information
- Funding Instrument: Grant
- Funding Category: Research and Development
- Budget Mechanism Code: RP - Research Projects
Allowable costs include (but are not limited to):
- Salary and fringe benefits for Principal Investigator, key personnel, and other essential personnel
- Equipment and supplies
- Consultant costs
- Alterations and renovations
- Publications and miscellaneous costs
- Contract services
- Consortium costs
- Facilities and Administrative costs (indirect costs)
- Travel expenses
Application and Submission Information
Parent Announcements
R01 Parent Announcements are available.
Parent announcements are broad funding opportunities that applicants can use to submit investigator-initiated applications for a range of popular programs. They do not specify any particular area of scientific interest. They simply provide the standard forms and instructions needed to apply.
Not all NIH institutes and centers participate on all parent announcements. Check the participating organization in the funding opportunity before applying.
Application Characteristics
- R01 application budgets are generally not limited but need to reflect the actual needs of the proposed project. Any opportunity-specific budget limits are indicated in Part 2. Section 2. Award Budget of the funding opportunity.
- NIH's Modular Budget Policy applies to R01 applications submitted by domestic organizations.
- Applications are generally awarded for 1-5 budget periods, each normally 12 months in duration.
- Applications can be renewed by competing for an additional project period.
After identifying a funding opportunity, follow guidance in the How to Apply – Application Guide including any Research (R) instruction call-outs, except where instructed to do otherwise in the funding opportunity or related notices.
Due Dates
The Key Dates section of funding opportunities lists specific due dates. Many opportunities indicate Standard Due Dates apply.
Standard Application Due Dates (when applicable) | Review and Award Cycles | ||||
New | Renewal, Resubmission, Revision as Allowed |
AIDS and AIDS Related Grant Applications |
Scientific Merit Review | Advisory Council Review |
Earliest Start Date |
Participating Funding Organizations
Each funding opportunity specifies the participating organizations. Applications must fit within the mission of at least one participating funding organization and meet all opportunity-specific requirements.
The following funding organizations participate on at least one active funding opportunity.
- Division of Program Coordination, Planning and Strategic Initiatives, Office of Disease Prevention (ODP)
- Division of Program Coordination, Planning and Strategic Initiatives, Office of Research Infrastructure Programs (ORIP)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- Fogarty International Center (FIC)
- National Cancer Institute (NCI)
- National Center for Complementary and Integrative Health (NCCIH)
- National Eye Institute (NEI)
- National Heart, Lung, and Blood Institute (NHLBI)
- National Human Genome Research Institute (NHGRI)
- National Institute of Allergy and Infectious Diseases (NIAID)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
- National Institute of Biomedical Imaging and Bioengineering (NIBIB)
- National Institute of Dental and Craniofacial Research (NIDCR)
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- National Institute of Environmental Health Sciences (NIEHS)
- National Institute of General Medical Sciences (NIGMS)
- National Institute of Mental Health (NIMH)
- National Institute of Neurological Disorders and Stroke (NINDS)
- National Institute of Nursing Research (NINR)
- National Institute on Aging (NIA)
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- National Institute on Deafness and Other Communication Disorders (NIDCD)
- National Institute on Drug Abuse (NIDA)
- National Institute on Minority Health and Health Disparities (NIMHD)
- National Library of Medicine (NLM)
- Office of AIDS Research (OAR)
- Office of Behavioral and Social Sciences Research (OBSSR)
- Office of Research on Women's Health (ORWH)
- Office of The Director, National Institutes of Health (OD)
- Sexual and Gender Minority Research Office (SGMRO)
- Tribal Health Research Office (THRO)
Contact
- Your organization's sponsored programs office or grants administrators can answer many internal and agency policy and process questions.
- Understand NIH Staff Roles details how and when to find the right NIH contacts:
- Before you apply, check your chosen funding opportunity for application submission, scientific/research, peer review, and financial/grants management contacts.
- After you apply, find NIH staff assignments in the Status module of eRA Commons.
This page last updated on: December 12, 2024
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