Midcareer Investigator Award in Patient-Oriented Research (Parent K24 – Independent Clinical Trial Required) (PA-24-187)

NCCIH Specific Information:

NCCIH uses the K24 program to support midcareer investigators interested in mentoring new/early-stage investigators in clinical patient-oriented research.

• Before the application receipt date, investigators are strongly encouraged to discuss their proposed research interest with an NCCIH Program Officer in the specific scientific area and/or intervention that is closely-related to the proposed project to confirm its relevance to NCCIH's mission and research priorities. A list of NCCIH program officials can be found at http://NCCIH.nih.gov/grants/contact#area. 
• NCCIH requires applicants to demonstrate a partnership with a Clinical and Translational Science Award (CTSA) institutional Consortium, which will provide resources to facilitate the development of beginning clinical investigators.
• The K24 applicant is required to have at least one active, independent, peer-reviewed R01 or R01-like grant funding, which includes peer-reviewed research grants from other federal sources, private foundations, or industry at the time of application.  The PI is expected to maintain such research grant support during the project period.  
• Applications should describe a research plan that focuses on mentoring opportunities for junior clinical researchers, utilizing currently funded research and previously collected datasets. New research may also be proposed but should be clearly related to mentoring activities.

 
Additional information about NCCIH’s use of the K24 is available at: http://NCCIH.nih.gov/grants/K24supplement.htm

Salary Support: Up to the maximum legislative salary cap plus fringe benefits per year, for 25-50% effort. Renewal applications are limited to a maximum of 30% effort.
Research Support: Up to $50,000 per year.

NHLBI Specific Information:

NHLBI will provide PI salary support of 25% or 3.0 calendar months’ effort up to the maximum legislative salary cap plus fringe benefits per year. Applications requesting more than 3.0 calendar months of PI salary support will not be reviewed.

A K24 award may be renewed one time by NHLBI. An individual may not receive more than a total of 10 years of K24 funding (new and renewal). See NOT-HL-16-442.

Individual Eligibility: At the time of application, individuals who are associate professors or full professors within 10 years of their appointment as an Associate Professor are eligible to submit a new NHLBI K24 application.
 

The NHLBI will consider requests to extend the eligibility period for reasons that can include medical concerns, disability, family care responsibilities, natural disasters, and active-duty military service. In general, the NHLBI will extend eligibility for a period equivalent to the time away from faculty service. Extensions related to periods of part-time status normally will be prorated to reflect the actual time away from faculty service and normally will be considered only when the appointment is reduced by 50% or more for a sustained period of time.

At the time of application submission, K24 applicants are required to have active, independent (as PI or MPI), peer-reviewed R01 or R01-like grant funding (including peer-reviewed research grants from other federal sources, private foundations, or industry) that supports research within the programmatic purview of NHLBI. It is highly recommended that prospective applicants contact the program representative to confirm their work is appropriate for NHLBI. Grants under a no-cost extension do not qualify. The PI is expected to maintain such research grant support during the project period.

The NHLBI will accept an application from an eligible individual that proposes a plan for training early clinician scientists to conduct Patient-Oriented clinical, biomedical or behavioral research aligned with NHLBI’s mission areas, which include, but are not limited to, cardiovascular, pulmonary, hematologic health and diseases, sleep disorders, circadian biology, or transfusion medicine. For the definition of Patient-Oriented Research see the Funding Opportunity Description section of the Parent Announcement. It is incumbent on the applicant to clearly describe opportunities for the mentees to receive training in patient-oriented research, which must include direct interaction with patients or other human participants.  

NHLBI encourages, but does not require, Mid-Career Investigator Award applications that propose a plan for mentored training of junior investigators in patient oriented research using data science methods, including, but not limited to, Artificial Intelligence, Machine Learning, Deep Learning, Healthcare Data Analytics, Public Health Data Analytics, Imaging Analytics, Predictive Analytics, and Bioinformatics, for the creation, management, analysis, and integration of complex, large data sets in support of data-driven discovery in heart, lung, blood, and sleep health and disease. Proposals must meet patient-oriented research requirements and all other requirements specified in the parent announcement.

Salary Support: Up to the maximum legislative salary cap plus fringe benefits per year, for 25% effort.
Research Support: Up to $50,000 per year.

National Institute on Alcohol Abuse and Alcoholism (NIAAA) 
 
Scientific Program Contact: 
NIAAA Staff Contact 
  
Grants Management Contact: 
Judy Fox 
Phone: (301) 443-4704 
Email: [email protected]

Lauren Early 
Phone: (301) 443-2434 
Email: [email protected]

NIAID Specific Information:

The K24 applicant is required to have an active, independent, peer-reviewed R01 or R01-like grant funding, which includes peer-reviewed research grants from other federal sources, private foundations, or industry at the time of application.  The PD/PI is expected to maintain such research grant support during the project period.  Only applicants at ranks of Associate Professor or equivalent and who have completed their terminal research degree or end of post-graduate clinical training, whichever date is later, within the past 15 years, are eligible to apply. Effective for application due dates on or after June 12, 2024, NIAID will no longer accept renewal (Type 2) applications for this mechanism.

For more information see the NIAID web page, See https://www.niaid.nih.gov/grants-contracts/career-development-awards for more details on NIAID Career Development Awards.     

Salary Support: Up to the maximum legislative salary cap plus fringe benefits per year, for 25-50% effort.
Research Support: Up to $50,000 per year.

NIDCD Specific Information:  

NIDCD uses the K24 to support well-established research investigators in an area of research supported by the NIDCD and with active, peer-reviewed, independent research support from the NIDCD at the time of submission interested in mentoring the next generation of basic, clinical and translational investigators in NIDCD’s research areas.

• Applicants must have mid-career faculty appointment at the associate professor level or higher.
• Applicants must be part of a Clinical and Translational Science Award (CTSA) that will provide resources to facilitate the development of beginning clinical investigators.

 
Salary Support: Up to the maximum legislative salary cap plus fringe benefits per year, for 25-50% effort.
Research Support: Up to $50,000 per year.

NIDA Specific Information:
 
NIDA encourages research investigators with an active, peer-reviewed, and independently supported research program in the field of substance use/substance use disorders to consider mentoring the next generation of patient-oriented researchers while also enhancing their own research programs using the K24 mechanism.

• Applicants must have a mid-career faculty appointment at the Associate Professor level or higher.
• NIDA limits support under this mechanism to 10 aggregate years; thus, if an applicant has had 5 years of K24 support from another NIH IC, the applicant will be eligible for only 5 years of K24 support from NIDA. 

Potential applicants are encouraged to contact NIDA program staff to determine eligibility and to discuss their interests in this program.

Salary Support: Up to the maximum legislative salary cap plus fringe benefits per year, for 25-50% effort.
Research Support: Up to $50,000 per year. Examples include supplies, equipment, technical personnel, travel, and statistical services.

NIEHS Specific Information:

NIEHS accepts new applications from mid-career investigators who have active, peer reviewed, independent research support in patient- oriented research (R01 or R01-like grant funding or peer-reviewed research grants from other federal sources, private foundations, or industry) in areas within the NIEHS mission.  The PI is expected to maintain such research grant support during the project period.  Mentoring programs proposed in the K24 application should be designed to increase the number of clinically trained scientists with research interests in the environmental health sciences. For further information on the research interests of the Institute, please see: https://www.niehs.nih.gov/.

Potential applicants are strongly encouraged to contact the program official identified in the contact table before preparing an application to discuss eligibility requirements and the relevance of the proposed research to the Institute’s research priorities.

Salary Support: Up to the maximum legislative salary cap plus fringe benefits per year, for 25-50% effort.
Research Support: Up to $50,000 per year.

NIMHD Specific Information:

NIMHD K24 awards provide support to mid-career health professionals with doctoral or equivalent degrees for protected time to devote to patient-oriented research and to act as research mentors primarily for clinical residents, clinical fellows and/or junior clinical faculty. The K24 applicant (new or renewal) is required to have active, independent (as PI or MPI), peer-reviewed R01 or R01-like grant funding (including peer-reviewed research grants from other federal sources, private foundations, or industry) that supports research within the programmatic purview of NIMHD (see Research Interest Areas). Grants in no cost extension do not meet that requirement. The PI is expected to maintain such research grant support during the project period.

Individual Eligibility: At the time of application, individuals who are Associate Professors or Full Professors within 10 years of their appointment as an Associate Professor are eligible to submit a new or resubmitted NIMHD K24 application. The NIMHD will consider requests to extend the eligibility period for reasons that can include medical concerns, disability, family care responsibilities, natural disasters, and active duty military service.

It is highly recommended that prospective applicants contact the program representative before preparing an application to discuss eligibility requirements and the relevance of the proposed research to the Institute’s research priorities.

Salary Support: Up to the maximum legislative salary cap plus fringe benefits per year, for 25% effort (i.e., 3.0 calendar months).  Applications requesting more than 3.0 calendar months of PI salary support will not be reviewed.
Research Support: Up to $50,000 per year.

NIH Office of Data Science Strategy (ODSS)

ODSS program contact: 
Bryan Kim Ph.D.
Email: [email protected]

Office of Data Science Strategy Specific Information:

The NIH Office of Data Science Strategy (ODSS) is committed to growing a strong and diverse data science community and ensuring that data science advances in biomedical and health research can benefit all populations. ODSS is interested in supporting Career Development Award projects in data science areas including but not limited to: artificial intelligence, clinical informatics, cloud computing, statistics, computational science, software design and programming, bioinformatics, visualization, machine learning, predictive analytics, supercomputing, modeling and simulation, digital health, data sharing and access, data management, data security and data privacy in human subject’s research, and research ethics and integrity. Applications are strongly encouraged from individuals from diverse backgrounds, including from groups that are underrepresented in the biomedical, clinical, behavioral and social sciences, in alignment with the Notice of NIH’s Interest in Diversity (NOT-OD-20-031).

Office of Research on Women’s Health

Scientific Program Contact: 
Carolyn Bondar, Ph.D. 
Phone: (301) 824-7194 
Email: [email protected]

ORWH Specific Information:

ORWH focuses on advancing research that is relevant to the health of women and supporting women in biomedical careers. Applicants should ensure their proposed work intersects with the goals, objectives, and guiding principles of the trans-NIH Strategic Plan for Women’s Health Research (https://orwh.od.nih.gov/about/trans-nih-strategic-plan-womens-health-research). ORWH does not award grants but co-funds applications and research projects that have received an award from one of the participating NIH Institutes and Centers listed in the announcement. Visit the ORWH website (https://orwh.od.nih.gov/) or contact the appropriate ORWH staff to learn more.