Research Enhancement Awards (R15)

Purpose

• Support meritorious research. 
• Expose students to research. 
• Strengthen the research environment of the institution. 

Overview

There are two R15 programs: 

• Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions 
• Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools

Proposed research must fall within the mission and interests of a participating NIH institute or center. See NIH R15 Research Areas Listed by NIH Institute for program research topics of particular interest.

R15 Webinar: What You Need to Know 

Mark your calendars for the next NIH Research Enhancement Award (R15) Webinar: What You Need to Know… And Recent Changes on Thursday, January 30, 2025, from 2:30 pm - 4:00 pm. Learn about the two NIH R15 programs, gain insights into the application process and the review criteria, and participate in a live question and answer session with a panel of NIH experts. We also offer Frequently Asked Questions on R15. 

You can also check the previous June 15, 2023 Webinar Video, Transcript, and Slide Deck to learn about NIH R15 programs and watch a panel of NIH experts answer questions.  

R15 Eligibility Decision Tree

R15 Eligibility Decision Tree (Accessible PDF - 168 KB)

Award Data

Find data on R15 Competing Applications, Awards, Success Rates and Total Funding on the NIH Research Portfolio Online Reporting Tools (RePORT) website. RePORT provides information about NIH research grants, including the number of funded new and competing awards, average award dollars, and characteristics of research project grants.

Organization Eligibility

• Eligibility: U.S. domestic institutions

To determine eligibility, organizations are encouraged to use the NIH RePORT website. Find guidance at Need Help Determining Organization Funding Levels for R15 Eligibility? 

Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions​ 

• For the AREA R15 program: 
  • An academic component is any school/college that is not a Health Professional School or College. 
  • A qualifying academic component (i.e., school/college) within an organization (e.g. School of Arts and Sciences) has greater undergraduate student enrollment than graduate student enrollment. 
  • All types of Health Professional Schools and Colleges are not eligible to apply,
• The application must be submitted by the eligible undergraduate-focused organization with a unique entity identifier (SAM-issued UEI) and a unique NIH eRA Institutional Profile File (IPF) number. 
• For organizations with multiple campuses, eligibility can be considered for each individual campus (e.g. main, satellite, etc.) only if separate UEIs and NIH IPF numbers are established for each campus. For organizations that use one UEI or NIH IPF number for all campuses, eligibility is determined for all campuses (e.g. main, satellite, etc.) combined. 
• The applicant organization must be an accredited public or non-profit private school that grants baccalaureate degrees in biomedical sciences. 
• At the time of application submission, all the non-health professional components of the organization together have not received support from the NIH totaling more than $6 million per year (in both direct and F&A/indirect costs) in 4 of the last 7 federal fiscal years. Note that all activity codes are included in this calculation except the following: C06, S10, and all activity codes starting with a G. 
• A signed letter is required from the Provost or similar official with organization-wide responsibility verifying the eligibility of the applicant organization at the time of application submission. 

Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools 

• The application must be submitted by the eligible health professional or graduate school with a unique entity identifier (SAM-issued UEI) and a unique NIH eRA Institutional Profile File (IPF) number. 
• For organizations with multiple campuses, eligibility can be considered for each individual campus (e.g. main, satellite, etc.) only if separate UEIs and NIH IPF numbers are established for each campus. For organizations that use one UEI or NIH IPF number for all campuses, eligibility is determined for all campuses (e.g. main, satellite, etc.) combined. 
• The applicant organization must be an accredited public or non-profit private school that grants baccalaureate or advanced degrees in health professions or advanced degrees in biomedical and behavioral sciences. 
• At the time of application submission, all components of the applicant organization combined may not have received support from the NIH totaling more than $6 million per year (in both direct and F&A/indirect costs) in 4 of the last 7 federal fiscal years. Note that all activity codes are included in this calculation except the following: C06, S10, and all activity codes starting with a G. 
• A signed letter is required from the Provost or similar official with organization-wide responsibility verifying the eligibility of the applicant organization at the time of application submission.

Project Director/ Principal Investigator (PD/PI) Eligibility

• The PD/PI must have a primary appointment at the R15-eligible organization.
• Additionally, for:
  • AREA: Each PD/PI(s) must have a primary appointment at a non-health professional school or college within the applicant organization. If proposing multiple PD/PIs, each PD/PI must be at an AREA-eligible organization.
  • REAP: Each PD/PI(s) must have a primary appointment at a health professional or graduate school or college within the applicant organization. If proposing multiple PD/PIs, each PD/PI must be at a REAP-eligible organization.
• The PD/PI may not be the PD/PI of an active NIH research grant at the time of a R15 award, though the PD/PI may be one of the Key Personnel for an active NIH grant held by another PD/PI.
  • Instrumentation awards (S10), conference grants (R13), and institutional training grants (T32) are examples of grants that are not considered research grants.
• The PD/PI may not be awarded more than one R15 grant at a time.
• Eligibility applies only to the PI and Multiple PIs, not to collaborators, consultants, or subawardees.

Award Information

• Funding Instrument: Grant
• Funding Category: Research and Development
• Budget Mechanism Code: RP - Research Projects
• Multi-year Funded: Yes

• Project Period: Limited to 3 years
• NIH's Modular Budget Policy applies:
  • Applicants submitting an application with direct costs of $250,000 or less (total for all years, excluding consortium Facilities and Administrative [F&A] costs) must use the Modular Budget.
  • Applicants submitting an application with direct costs of $250,001-$375,000 (total for all years, excluding consortium Facilities and Administrative [F&A] costs) must use the Research and Related (R&R) Budget form.
• Awards can be renewed by competing for an additional project period.

Application and Submission Information

• The application should propose a research team, including undergraduate and/or graduate students, that is appropriate to accomplish the specific aims and to make an important scientific contribution. 
• A signed letter is required from the Provost or similar official with organization-wide responsibility verifying the eligibility of the applicant organization at the time of application submission.
• Sample application attachments 
  • Sample Provost Letters Certifying R15 Eligibility
  • Sample R15 Biosketch Personal Statement 
  • Sample Facilities and Other Resources 

After identifying a funding opportunity, follow guidance in the How to Apply – Application Guide including any Research (R) instruction call-outs, except where instructed to do otherwise in the funding opportunity or related notices.