Animals in NIH Research

NIH supports biomedical research to seek fundamental knowledge about the nature and behavior of living systems and apply that knowledge to enhance health, lengthen life, and reduce illness and disability. Because of NIH research, Americans and many others around the world are living longer and healthier lives.

Biomedical and behavioral research can involve working with cells in test tubes, computer modeling, laboratory animals, and clinical studies with people. Each kind of research plays a critical role in advancing our knowledge of health and disease. What we have learned from research with laboratory animals (also referred to as “animal models”) has provided the foundation for many safe and effective life-saving treatments for diseases and conditions affecting human health.

Laws, regulations, and policies dictate the requirements that protect animals used in federally funded research. These protections require  consideration of non-animal alternatives to meet the scientific objectives. They  ensure that the fewest numbers needed for thorough and repeatable results are chosen. They also outline standards that reflect the greatest commitment to animal care.

NIH's Commitment

NIH is committed to supporting ethically conducted, high quality research, which is guided by principles, regulations, and laws. Ensuring that animals receive the best possible care and treatment within the context of research is critical to achieving rigorous, reliable, and scientifically valid results.