ORWH Clinical Trials

The Office of Research on Women's Health (ORWH) supports biomedical and biobehavioral clinical research by co-funding grants, contracts, cooperative agreements, institutional and individual career awards, administrative supplements and NIH intramural research that improves understanding of sex influences on health and disease and promotes the development of evidence-based prevention, diagnostic, and treatment strategies.

Interest areas include:

• Clinical studies on conditions that present, progress, or impact women differently or disproportionately.
• Clinical research that advances understanding of sex differences and incorporates sex as a biological variable (SABV) across the research continuum - design, analysis, interpretation, and dissemination - to improve scientific rigor and relevance.
• Studies that strengthen the inclusion of women in clinical research and improve strategies for participant engagement, recruitment, retention, and analysis.
• Clinical research that advances women’s health across the life course, including studies that consider biological, behavioral, social, and environmental factors that influence sex-specific biology.
• Studies that translate women’s health research findings into evidence‑based clinical or public health practice.

The Office of Autoimmune Disease Research in ORWH (OADR-ORWH) is interested in clinical trials focused on improving treatment and advancing cures for autoimmune disease.

This office does not award grants. Applications must be relevant to the objectives of at least one of the participating Institutes or Centers listed in this topic.