NIBIB Clinical Trials

NIBIB only supports mission-focused early-stage clinical trial applications, i.e., feasibility, Phase I, first-in-human, safety, or other small clinical trials, that inform early-stage technology development. Mechanistic clinical trials are not supported unless the primary focus of the project is on technology development.

• NIBIB has a particular interest in clinical trials with a primary focus on technology development for:
  • Feasibility clinical trials
  • First-in-human clinical trials
  • Phase I clinical trials
• NIBIB does NOT support:
  • Pivotal trials
  • NIH-defined phase II, III, IV clinical trials
  • Trials with efficacy, effectiveness or post-market concern as primary outcome.

If applicants have questions whether or not the above applies to their application, reach out to your program officer or the contacts listed below prior to submitting