Sex As a Biological Variable

NIH expects that sex as a biological variable (SABV) will be factored into research designs, analyses, and reporting in pre-clinical and clinical studies. Accounting for SABV helps interpret and validate research findings, as well as enhances the rigor, reproducibility, and applicability of biomedical research. But how exactly do you account for SABV?

Dr. Chyren Hunter with the NIH Office of Research on Women’s Health explains more in this NIH All About Grants podcast episode. She outlines what the policy is (and what it is not), how applicants can address SABV, its effect on budgets, peer review considerations, training opportunities, reporting, and much more.
 
“… The thing to remember is that the study of sex and gender is part of rigorous and reproducible research, and when we have a complete knowledge base on sex and gender, we can use that to build… better treatments and cures that… advance the health of all of us. And so we should look at SABV as an opportunity…” - Dr. Chyren Hunter

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This page last updated on: January 6, 2025
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