Mentored Clinical Scientist Research Career Development Award (Parent K08 – Independent Clinical Trial Required) (PA-20-202)

PA-20-202

Table of IC-Specific Information, Requirements and Staff Contacts

Release Date: May 12, 2020
Expiration Date: May 8, 2023

NIH Institute or Center Contacts	Institute/Center Specific Information
National Cancer Institute (NCI) Scientific Program Contact: Sergey Radaev, Ph.D Email: sradaev@mail.nih.gov Grants Management Contact: Amy Bartosch Email: Amy.Bartosch@nih.gov	The NCI K08 award provides support and “protected time” to postdoctoral, and non-tenured junior faculty (e.g., Assistant Professor or equivalent) clinician-scientists for intensive mentored research and career development activities in basic, translational, and/or patient-oriented cancer research. See NOT-CA-17-042 and NOT-CA-17-043 for details. The application will not be considered for funding if the PD/PI has already been promoted to Associate Professor or equivalent at the time of award. Eligible candidates must be clinicians who practice in the United States. Candidates (other than surgeon-scientists) are required to devote a minimum of 9 person months (75%) full-time professional effort to the K08 award. Candidate must maintain an active clinical license during the K08 award. A copy of active U.S. licensure must be included in the application under “Other Attachments”. NCI allows U.S.-licensed surgeon-scientists with active surgical duties to request less than the required 9 person months (75%) full-time professional effort under a K08 career development award. They may not request less than 6 person months (50%) full-time professional effort devoted to research and career development activities. These applicants must provide a justification clearly stating the reason(s) for the reduced (less than 75%) amount of effort in (1) Candidate’s Plan for Career Development/Training Activities During Award Period, (2) Mentor's letter, and (3) Institutional commitment letter. For details, please see NOT-CA-21-054. Prospective applicants are strongly encouraged to contact the Program Director with their NIH biosketch, specific aims, and information on their clinical training and clinical licensure prior to application. Additional NCI-specific information/requirements can be found at: http://www.cancer.gov/grants-training/training/funding/K08. For Diversity Career Development Awards, please see the Center to Reduce Cancer Health Disparities (CRCHD) at http://crchd.cancer.gov/diversity/cure-overview.html. Salary Support: Up to the legislative salary cap (/grants/policy/salcap_summary.htm) plus fringe benefits per year. Research Support: Up to $50,000 per year.
National Eye Institute (NEI) Scientific/Research: Neeraj Agarwal, Ph.D. Phone: (301) 451-2020 Email: agarwalnee@mail.nih.gov Grants Management Contact: Karen Robinson-Smith Phone: (301) 451-2020 Email: karen.robinson.smith@nei.nih.gov	NEI Specific Information: NEI has a 6 years limit of cumulative support on institutional and mentored Ks (e.g., K12 or KL2 plus the K08). Eligibility: Eligible candidates must have a health professional doctoral degree, such as the M.D., M.D./PhD; D.O., D.O./PhD; O.D.; O.D./PhD; D.V.M., D.V.M/PhD; or equivalent degree, and a professional clinical license to practice medicine in the United States. Candidates are required to devote a minimum of 75% full-time professional effort to the K- award. A copy of active U.S. licensure must be included in the application. Scholars who are ophthalmic surgeons may request between 6 and 9 person-months (50% to 75%) of full-time professional effort conducting research and career development activities. Clinical Trials (CT): NEI will only accept “Mechanistic or Minimal Risk CTs” under this FOA. A mechanistic trial is defined as "A study designed to understand a biological of behavioral process, the pathophysiology of a disease, or the mechanism of action of an intervention. "Minimal risk" means that the probability and magnitude of harm or discomfort anticipated in the research are not greater in and of themselves than those ordinarily encountered in daily life or during the performance of routine physical or psychological examinations or tests. Salary Support: Up to the current legislative cap, plus fringe benefits, per year. The total salary requested must be based on a full-time, 12 month staff appointment for at least 75% effort. Research Support: Up to $25,000 per year.
National Heart, Lung, and Blood Institute (NHLBI) Scientific Program Contact: Marisol Espinoza-Pintucci, Ph.D. Phone: (301) 496-1898 Email: marisol.espinoza-pintucci@nih.gov Karin F. Lidman, Ph.D. Phone: (301) 435-0535 Email: fredrikssonk@mail.nih.gov Grants Management Contact: Taryn Cobb Phone: (301) 827-8025 Email: taryn.cobb@nih.gov	NHLBI Specific Information: NHLBI has an 8 year limit of cumulative support on institutional and mentored Ks (e.g., K12 or KL2 plus the K08). Eligibility: Candidates must have a health professional doctoral degree, such as the M.D., D.O., D.V.M., or equivalent degree, and a professional license to practice in the United States. Documentation of active licensure should be included in the application. Advisory Committee: NHLBI strongly encourages K08 candidates to include an Advisory Committee composed of the candidate's mentor(s) and two or three other senior faculty members. If the candidate does not propose an Advisory Committee, she/he should document which individuals are available to cover all areas of expertise that are required for the research plan and career development. NHLBI encourages career development award applications that propose mentored training in data science disciplines, including but not limited to Artificial Intelligence, Machine Learning, Deep Learning, Healthcare Data Analytics, Public Health Data Analytics, Imaging Analytics, Predictive Analytics, and Bioinformatics, for the creation, management, analysis, and integration of complex, large data sets in support of data-driven discovery in heart, lung, blood, and sleep health and disease. Proposals must meet all other requirements specified in the parent announcement. Concurrent Competing Applications: K08 applicants may not hold any other Federal or non-Federal equivalent salary award. Application Material: NHLBI suggests that K08 applications include biographical sketches of the collaborators and consultants. Salary Support: Up to $100,000 plus fringe benefits per year. Research Support: Up to $25,000 per year.
National Human Genome Research Institute (NHGRI) Scientific Program Contact: Heather A. Colley, M.S. Phone: (301) 480-2332 Email: junkinsh@mail.nih.gov Grants Management Contact: Deanna Ingersoll Phone: (301) 435-7858 Email: Deanna.Ingersoll@nih.gov	NHGRI Specific Information: NHGRI supports resources, approaches, and technologies that accelerate genomic research focused on the ethical, legal, and social implications of genomic advances; the structure and biology of genomes; the genomics of disease; the implementation and effectiveness of genomic medicine; computational genomics and data science; and the impact of genomic advances, technology, and implementation on health disparities and health equity. Within these areas, approaches that are comprehensive across the genome or are generalizable across variants, tissues, diseases, or functions may be in scope for NHGRI. NHGRI recognizes the importance of diversity in the genomic workforce, without which the promise of genomics cannot be fully achieved. All K08 applicants must justify the need for additional training and explain how the training will facilitate their ability to conduct cutting-edge research in the research areas outlined above. Prospective applicants are strongly encouraged to contact the Scientific Program Contact to discuss their concept for this initiative during the development stages of the application. Salary Support: Commensurate with the applicant institution's salary structure for persons of equivalent qualifications, experience, and rank. Research Support: Up to $40,000 per year. In addition to Research Support, awardees are strongly encouraged to attend at least one NHGRI Research Training and Career Development Annual Meeting while supported on the K08. Travel may be requested up to $1500 each per NHGRI meeting.
National Institute on Aging (NIA) Scientific Program Contact: NIA Training Office Email: NIAtraining@nih.gov Grants Management Contact: Traci Lafferty, NIA Phone: (301) 496-1472 Email: laffertt@mail.nih.gov	NIA Specific Information: See: http://www.nia.nih.gov/research/dea/research-training-and-career-award-support . Salary Support: Up to $100,000 plus fringe benefits per year. Research Support: Up to $25,000 per year.
National Institute on Alcohol Abuse and Alcoholism (NIAAA) Scientific Program Contact: Svetlana Radaeva, Ph.D. Phone: (301) 443-1189 Email: sradaeva@mail.nih.gov Grants Management Contact: Judy Fox Phone: (301)443-4704 Email: jfox@mail.nih.gov	NIAAA Specific Information: NIAAA supports faculty level early stage investigators and new investigators through career development awards by providing protected time and mentoring in an environment where they can develop the skills and expertise for independent research. Under this announcement mentored research must focus on NIAAA’s research priorities as described in NIAAA Strategic Plan . Examples, include but are not limited to research in social, behavioral, biological, mathematical sciences, and health services as related to alcohol use disorder and alcoholism. Potential applicants are strongly encouraged to contact the program official identified in the contact table before preparing an application to discuss eligibility requirements and the relevance of the proposed research to the Institute’s research priorities. All applications must include a strong and credible plan for the applicant's transition to research independence, outlining milestones and providing evidence of significant institutional commitment to the development of the K applicant as an independent researcher at the sponsoring institution. Candidates with less than 4 years of post-doctoral research experience, who are enrolled in the T32 training programs are strongly encouraged to apply for a K99/R00 award. At the time of the award, the candidate must have a secured full time faculty or faculty equivalent appointment in an appropriate research-intensive environment. The application must also provide a document on institutional letterhead that describes its commitment to the candidate and the candidate's career development, independent of the receipt of the K award. It is also essential to document the institution's commitment to the retention, development, and advancement of the candidate during the period of the award. For additional information about NIH requirements for the institution’s commitment letter, applicants are referred to G.410 - PHS 398 Career Development Award Supplemental Form instructions under Institutional Commitment to Candidate's Research Career Development. Applications that include human subject research must comply with NIAAA policy on providing plans for submitting grant-related human subjects data to a NIAAA-sponsored data repository, the NIAAA Data Archive (NIAAA DA ), as described in NOT- AA- 19- 020. To help you decide which award best suits your needs, as well as additional guidance on application specifics, see Research Training and Career Development/Training Opportunities by Grant Mechanism . Potential applicants are strongly encouraged to contact the program official identified in the contact table before preparing an application to discuss eligibility requirements and the relevance of the proposed research to the Institute’s research priorities. Salary Support: Up to $100,000 plus fringe benefits per year. A minimum of 75% effort must be devoted to the career award. Research Support: Up to $50,000 per year.
National Institute of Biomedical Imaging and Bioengineering (NIBIB) Scientific Program Contact: Tina Gatlin, Ph.D. Phone: 301-480-1608 Email: christine.gatlin@nih.gov Grants Management Contact: Kathryn (Katie) Ellis Phone: 302-451-4791 Email: kellis@mail.nih.gov	NIBIB Specific Information: NIBIB uses the K08 to provide support and "protected time" for an intensive, supervised research career development experience for individuals with a clinical doctoral degree (e.g., M.D., D.D.S., D.M.D., D.O., D.C., O.D., N.D., D.V.M., Pharm.D., or Ph.D. in clinical disciplines), who are committed to a career in laboratory or clinically-based research in biomedical imaging and bioengineering. Applicants must be clinicians with active licensure. NIBIB will only support individuals who are within 10 years of the completion of their residency or fellowship. The duration of support can be 3 or 4 years. Under this FOA, NIBIB will only support applications proposing early stage clinical trials through Phase I, first-in-human, safety, feasibility, or other small clinical trials that inform the early stage technology development in the submitted application. NIBIB will not support applications proposing Phase II, III, IV or pivotal clinical trials, or trials in which the primary outcome is efficacy, effectiveness, or a post-market concern. Before preparing an application, prospective applicants are encouraged to fill out the NIBIB K08/K23 Eligibility Inquiry Form and forward it along with the requested attachments to the Scientific Program Contact in order to verify eligibility, determine if the application is appropriate for a K08 award through NIBIB, and ensure that the application is submitted to the appropriate FOA. Applicants whose applications include human subjects research are especially encouraged to contact the NIBIB Scientific Program Contact for guidance in advance of submitting an application, to ensure their proposed project is in compliance with NIH human subjects research and clinical trials’ policies (/policy/clinical-trials.htm) and consistent with the types of clinical trial applications that NIBIB supports. More information on this and other NIBIB Career Awards can be found here. Salary Support: Up to $105,000 plus fringe benefits per year. Research Support: Up to $40,000 per year.
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Scientific Program Contact: Dennis A. Twombly, Ph.D. Phone: (301) 451-3371 Email: dtwombly@mail.nih.gov Grants Management Contact: Bryan S. Clark, MBA Phone: (301) 435-6975 Email: clarkb1@mail.nih.gov	NICHD Specific Information: NICHD offers fellowships, training grants, and career development awards in areas relevant NICHD’s mission, including normal and abnormal human development; male and female fertility and infertility; developing and evaluating contraceptive methods; pregnancy and childbirth; prenatal and postnatal development; childhood development and behavior through adolescence; improving the safety and efficacy of pharmaceuticals for use in pregnant women, infants, and children; HIV infection and transmission, AIDS, and associated infections; pediatric growth and endocrine research; developmental biology and typical and atypical development; intellectual and developmental disabilities; reproductive biology and medicine; gynecologic health conditions, including pelvic floor disorders; childhood injury and critical illness; population dynamics; and medical rehabilitation. More detailed information and Program Staff contacts may be found at: https://www.nichd.nih.gov/about/org/der/branches, and for the National Center for Medical Rehabilitation Research at: http://www.nichd.nih.gov/about/org/ncmrr/Pages/overview.aspx. NICHD has a 6 year limit of cumulative support on institutional K awards (e.g., K12, KL2) and individual mentored K awards (e.g., K01, K08, K23, K25). Salary Support: Up to $100,000 plus fringe benefits per year. Research Support: Up to $25,000 per year.
National Institute on Deafness and Other Communication Disorders (NIDCD) Scientific Program Contact: Alberto L. Rivera-Rentas, Ph.D. Phone: (301) 451-3245 Email: riverara@nidcd.nih.gov Grants Management Contact: Christopher Myers Phone: (301) 402-0909 Email: myersc@mail.nih.gov	NIDCD Specific Information: NIDCD uses the K08 program to support individuals with a clinical/health-professional doctorate interested in supervised career development experiences in basic clinical research (not in patient-oriented research) that lead to research independence in biomedical, behavioral, or translational fields. Application must demonstrate its contribution to NIDCD and its fit to NIDCD's Mission, Research Priorities, and Strategic Plan. Applicants are strongly encouraged to provide clear evidence that adequate resources are available at the institution for the successful completion of the proposed research project. Applications should include explicit statements from the institution and the mentor(s) addressing the following: Detailed information about who will provide the necessary resources; Funding source and amount of additional funding (as needed); Support staff available and committed to the project; Availability of biostatistical support for the duration of the study - including the planning period; and A contingency plan (for the institution and mentor) for completion of the study in the event the awardee leaves the institution earlier than the end date of the award. Salary Support: Up to $100,000 plus fringe benefits. Non-surgeon scientists must devote a minimum of 75% full time professional effort to research and career development activities associated with the K award. Surgeon-scientists must devote a minimum of 50% full time professional effort to research and career development activities associated with the K award. Research Support: Up to $50,000 per year.
National Institute of Dental and Craniofacial Research (NIDCR) Scientific Program Contact: Anissa J. Brown, PhD Research Training and Career Development Branch National Institute of Dental and Craniofacial Research Telephone: (301) 594-4805 Email: anissa.brown@nih.gov Grants Management Contact: Dede Rutberg, MBA Grants Management Branch Phone: (301) 594-4798 Email: rutbergd@mail.nih.gov	NIDCR Specific Information: NIDCR supports mentored research training and career development of clinicians proposing dental, oral and craniofacial research that aligns with the NIDCR Strategic Plan. Prospective candidates must have a DDS, DMD, MD or other clinical doctoral degree and be at the postdoctoral or junior faculty level. The award requires a minimum of 75% full time professional effort for research career development. Dentists may use the award to pursue graduate research training that results in a PhD or equivalent degree. The remaining 25% full time professional effort may be devoted to clinical activities, including dental specialty training, or other activities complementary to research career development. Applicants are expected to provide evidence that adequate resources are available at the institution for the successful completion of the proposed research project. Detailed information should be provided about who will provide the necessary resources, including descriptions of the funding source(s) and amount of funds (as needed). Prospective applicants are strongly encouraged to contact NIDCR before preparing an application to discuss eligibility, the relevance of the proposed research to NIDCR’s research priorities, and for guidance on the proposed research and career development plans. Salary Support: Up to $100,000 plus fringe benefits per year. Research Support: Up to $25,000 per year.
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Scientific Program Contact: Diabetes, Endocrinology, and Metabolic Diseases: Lisa M. Spain, Ph.D. Phone: (301) 451-9871 Email: SpainL@niddk.nih.gov Digestive & Liver Diseases, Nutrition, and Obesity: David E. Saslowsky, Ph.D. Phone: (301) 594-8876 Email: David.Saslowsky@nih.gov Kidney and Urologic Diseases: Tracy L. Rankin, Ph.D. Phone: (301) 594-4748 Email: rankint@mail.nih.gov Hematologic Disorders: Terry Rogers Bishop, Ph.D. Phone: (301) 594-7726 Email: BishopT@mail.nih.gov Grants Management Contact: Aricia M. Ajose, MPA Phone: (301) 594-9023 Email: ajosea@mail.nih.gov	NIDDK Specific Information: The NIDDK wishes to promote the training of physician scientists who, in addition to being excellent clinicians, are excellent researchers. NIDDK limits support to a maximum of 6 years of combined institutional K (K12 or KL2) plus K08 funding. Information on the NIDDK K08 can be found at http://www2.niddk.nih.gov/Funding/TrainingCareerDev/K08.htm. The NIDDK provides further information on all K-award programs on our training and career development web site: http://www2.niddk.nih.gov/Funding/TrainingCareerDev/. Salary Support: Up to $100,000 plus fringe benefits per year. Research Support: Up to $25,000 per year.
National Institute on Drug Abuse (NIDA) Scientific Program Contact: Lindsey Friend, Ph.D. Telephone: (301) 594-4673 Email: NIDA_Training@nida.nih.gov Grants Management Contact: Carol Alderson Phone: (301) 827-6685 Email: ca10h@nih.gov	NIDA Specific Information: Salary Support: Up to $100,000 plus fringe benefits per year. Research Support: Up to $50,000 per year. Examples include supplies, equipment, technical personnel, travel, and statistical services. Please note that the aggregate total of NIH mentored career award support (both institutional and individual) cannot exceed 6 years. A prospective K08 applicant who was appointed to an institutional K12 award must contact NIDA prior to submitting an individual mentored K application to confirm eligibility. Please contact NIDA_Training@nida.nih.gov for additional details .
National Institute of Environmental Health Sciences (NIEHS) Scientific Program Contact: Carol Shreffler, Ph.D. Phone: (984) 287-3322 Email: Shreffl1@niehs.nih.gov Grants Management Contact: Ashley Singh Phone: (984) 287-3323 Email: ashley.singh@nih.gov	NIEHS Specific Information: Eligibility: In addition to the degree requirements in the FOA, candidates must have a professional license to practice in the United States. Documentation of active licensure should be included in the application. NIEHS limits the cumulative support on institutional and mentored Ks (e.g., K12 or KL2 plus the K08) to six years. The NIEHS supports research and career development in its mission area, which is to discover how the environment affects people in order to promote healthier lives. For further information on the research interests of the Institute, please see: https://www.niehs.nih.gov/ Salary Support: Up to legislated cap, plus fringe benefits per year. Research Support: Up to $40,000 per year.
National Institute of Mental Health (NIMH) Scientific Program Contact: NIMH Training Contacts Grants Management Contact: Rebecca Claycamp, MS, CRA Phone: (301) 443-2811 Email: rclaycam@mail.nih.gov	NIMH Specific Information: The NIMH supports a broad spectrum of basic and translational research, including basic neuroscience, human genetics, adult and developmental translational research, services and intervention research, and AIDS-related research (http://www.nimh.nih.gov/about/organization/nimh-extramural-research-programs.shtml). Eligibility for the K08 is limited to individuals with no more than 6 years of postdoctoral research experience at the time of application (either the initial or resubmission application). NIMH encourages applicants to limit the requested support to no more than four years. The requested duration of support should be appropriately justified, taking into consideration prior research experience and the proposed mentored career development goals that are essential for developing an independent, NIMH-funded research program. See NOT-MH-22-310 and http://www.nimh.nih.gov/funding/training/career-development-programs-k-series.shtml for further details about NIMH's support for K programs. An application must include a strong and credible plan for the candidate's transition to research independence, including milestones, and evidence of significant institutional commitment to the continued development of the K08 candidate as an independent researcher at the applicant institution. Applicants are expected to plan to apply for independent research support during the later years of their mentored career award. Candidates (other than neurosurgeons) must devote a minimum of 75% full time professional effort to research and career development activities associated with the K award. Neurosurgeons must devote a minimum of 50% full time professional effort to research and career development activities associated with the K award. Prospective applicants are strongly encouraged to contact Institute career development staff (http://www.nimh.nih.gov/funding/training/contacts-for-research-training-and-career-development-programs.shtml) before preparing an application to discuss the relevance of the proposed research to the Institute's current research priorities and for guidance on the proposed research and career development plans. Salary Support: Up to $100,000 plus fringe benefits per year. Research Support: Up to $50,000 per year.
National Institute of Neurological Disorders and Stroke (NINDS) Scientific Program Contact: Stephen Korn, Ph.D. Phone: (301) 496-4188 Email: korns@ninds.nih.gov Grants Management Contact: Chief Grants Management Officer Email: ChiefGrantsManagementOfficer@ninds.nih.gov	NINDS Specific Information: This program is intended to support applicants with a clinical doctoral degree, who are licensed to practice clinically, who are within 5 years of completing their clinical training (which is defined as sequential years of residency training and clinical fellowships). Applicants who are beyond 5 years post clinical training must obtain prior written approval from the Director, Office of Training & Workforce Development to be eligible for this program. NINDS mentored K awards may be for either 4 or 5 years (NINDS will not make K08 awards lasting only 3 years). Please see the NINDS training website for additional NINDS-specific information: https://www.ninds.nih.gov/Funding/Training-Career-Development/Award/K08-Mentored-Clinical-Scientist-Research-Career. Candidates for the K08 (other than neurosurgeons) must devote a minimum of 75% full time professional effort to research and career development activities associated with the K award. The letter of institutional commitment should include a description of the candidate's non-research responsibilities according to the following: 1/2 day = 10% of the 5-day workweek, 1 month = 8% of the year, time on call for clinical duty is not protected time for research. Neurosurgeons must devote a minimum of 50% full time professional effort to research and career development activities associated with the K award. The letter of institutional commitment should describe, as above, the specific allocation of time (on a weekly and/or monthly basis) devoted to K award activities and clinical and other non-K award activities. The allocated research support (see below) includes $1,000 dollars per year to help support attendance at two annual workshops associated with the ANA (American Neurological Association) meeting (neurosurgeons are encouraged to attend the meeting associated with the neurosurgeon K12 (NRCDP) instead). It is intended that K awardees will attend these workshops in the 1st and 4th year of their awards, but if personal conflicts make this impossible, alternatives can be acceptable. However, awardees will not be invited to attend in two consecutive years. If K awardees do not attend twice during the first 4 years of the K award, the research support in the 5th year of the award will be reduced to $46,000. Salary Support: Up to $125,000 plus fringe benefits per year. Research Support: Up to $51,000 per year.
National Institute on Minority Health and Health Disparities (NIMHD) Scientific Program Contacts: For initial inquiries contact: NIMHDtraining@nih.gov Grants Management Contact: Priscilla Grant, JD Phone: 301-594-8412 Email: pg38h@nih.gov	NIMHD Specific Information: NIMHD supports various mentored career development activities involving research to improve minority health and reduce health disparities, organized around three main Research Interest Areas: Clinical and Health Services Research, Community Health and Population Sciences, and Integrative Biological and Behavioral Sciences. Projects are encouraged to use approaches that encompass multiple domains of influence (e.g., biological, behavioral, socio-cultural, environmental, physical environment, health systems) and multiple levels of influence (e.g., individual, interpersonal, community, societal) to understand and address health disparities. See the NIMHD Research Framework for examples of health determinants of interest. Prospective applicants are strongly encouraged to contact the program official identified in the contact table before preparing an application to discuss eligibility requirements and the relevance of the proposed research to the Institute’s research priorities. Salary Support: Up to $100,000 plus fringe benefits per year. Research Support: Up to $25,000 per year.
National Center for Complementary and Integrative Health (NCCIH) Scientific Program Contact: Lanay Mudd, Ph.D. Phone: (301) 594-9346 Email: lanay.mudd@nih.gov nccihderinquiries@mail.nih.gov Grants Management Contact: Shelley Carow Phone: (301) 594-3788 Email: CarowS@MAIL.NIH.GOV	NCCIH Specific Information: NCCIH uses the K08 program to support individuals with a clinical/health-professional doctorate in supervised career development experiences in biomedical, behavioral, or translational fields that lead to research independence. Before the application receipt date, investigators are strongly encouraged to discuss their proposed research interest with an NCCIH Program Officer in the specific scientific area and/or intervention that is closely-related to the proposed project to confirm its relevance to NCCIH's mission and research priorities. A list of NCCIH program officials can be found at http://NCCIH.nih.gov/grants/contact#area. Applications proposing the use of natural products or devices in an interventional research project should explicitly describe the status of the Investigational New Drug (IND) or Investigational Device Exemption (IDE). Applicants interested in natural products research are encouraged to review NCCIH's Natural Product Integrity Policy. NCCIH will not fund applications proposing a clinical trial to test efficacy or effectiveness through this mechanism. Applicants are encouraged to discuss their proposed scope of work with an NCCIH program officer, and to review resources available at NCCIH’s Clinical Research Toolbox. Applicants are strongly encouraged to provide clear evidence that adequate resources are available at the institution for the successful completion of the proposed research project. Applications should include explicit statements from the institution and the mentor(s) addressing the following: Detailed information about who will provide the necessary resources; Funding source and amount of additional funding (as needed); Support staff available and committed to the project; Allocation of sufficient protected time for the K awardee to conduct the research; Availability of biostatistical support for the duration of the study - including the planning period; and A contingency plan (for the institution and mentor) for completion of the study in the event the awardee leaves the institution earlier than the end date of the award. Salary Support: Up to $100,000 plus fringe benefits per year. Research Support: Up to $25,000 per year.