This Program Announcement expires three years from the Release Date shown
directly below.
BASIC AND TRANSLATIONAL RESEARCH IN EMOTION: SMALL GRANTS
Release Date: June 15, 2000 (see replacement PA-03-169)
PA NUMBER: PA-00-106
National Institute of Mental Health
National Institute on Aging
National Institute on Alcohol Abuse and Alcoholism
National Cancer Institute
National Institute of Child Health and Human Development
National Institute on Drug Abuse
THIS PA USES "MODULAR GRANT" AND "JUST-IN-TIME" CONCEPTS. THIS PA INCLUDES
DETAILED MODIFICATIONS TO STANDARD APPLICATION INSTRUCTIONS THAT MUST BE USED
WHEN PREPARING AN APPLICATION IN RESPONSE TO THIS PA.
PURPOSE
This Program Announcement (PA) and PA-00-105 Basic And Translational
Research In Emotion (http://grants.nih.gov/grants/guide/pa-files/PA-00-105.html)
are revisions of PA-94-059, which was published in the NIH Guide on
April 29, 1994.
Under this PA, the National Institute of Mental Health (NIMH), the National
Institute on Aging (NIA), the National Institute on Alcohol Abuse and
Alcoholism (NIAAA), the National Cancer Institute (NCI), the National
Institute of Child Health and Human Development (NICHD), and the National
Institute on Drug Abuse (NIDA) invite research grant applications to expand
basic research on the processes and mechanisms involved in the experience and
expression of emotion.
HEALTHY PEOPLE 2010
The Public Health Service (PHS) is committed to achieving the health
promotion and disease prevention objectives of "Healthy People 2010," a PHS-
led national activity for setting priority areas. This PA, Basic and
Translational Research in Emotion, is related to various priority areas.
Potential applicants may obtain a copy of "Healthy People 2010" at
http://www.health.gov/healthypeople.
ELIGIBILITY REQUIREMENTS
Applications may be submitted by domestic, for-profit and non-profit
organizations, public and private, such as universities, colleges, hospitals,
laboratories, units of State and local governments, and eligible agencies of
the Federal government. Racial/ethnic minority individuals, women, and
persons with disabilities are encouraged to apply as principal investigators.
Foreign institutions are not eligible for R03 awards.
MECHANISM OF SUPPORT
This PA will use the National Institutes of Health (NIH) R03 (small grant)
award mechanism. Responsibility for the planning, direction, and execution
of the proposed project will be solely that of the applicant. The total
project period for an application submitted in response to this PA may not
exceed two years.
Funds must be requested in $25,000 direct cost modules. A maximum of 2
modules (up to $50,000 direct costs) per year for may be requested for R03
applications. The cost of equipment is included in the budget limitation.
Any necessary escalation must be included within the number of modules being
requested. Only limited budget information is required and any budget
adjustments made by the Initial Review Group will be in modules of $25,000.
More detailed information about modular grant applications, including a
sample budget narrative justification pages and a sample biographical sketch,
is available via the Internet at:
http://grants.nih.gov/grants/funding/modular/modular.htm.
Applicants are strongly encouraged to consult with program staff (listed
under INQUIRIES) and to obtain the appropriate additional announcements for
the small grant mechanism. Special instructions and information for the
various small grant programs are found via the Internet at:
http://grants.nih.gov/grants/guide/pa-files/PAR-99-140.html (NIMH)
http://grants.nih.gov/grants/guide/pa-files/PA-99-049.html (NIA)
http://grants.nih.gov/grants/guide/pa-files/PAR-99-098.html (NIAAA)
http://grants.nih.gov/grants/guide/pa-files/PAR-97-006.html (NCI)
http://grants.nih.gov/grants/guide/pa-files/PAR-99-126.html (NICHD)
http://grants.nih.gov/grants/guide/pa-files/PAR-97-038.html (NIDA)
RESEARCH OBJECTIVES
Background
The study of emotion encompasses a wide range of psychological, social,
developmental, and biological phenomena, including characteristic expressive
signals, alterations in physiology, and subjective feeling states. Central
and autonomic nervous system (CNS, ANS) activity and the role of cognitive
processing in emotion also are important objects of study, as is the
contribution of emotional and motivational systems to cognitive faculties
such as perception, attention, memory, and motor control. In addition, the
study of emotion includes overt behavioral responses such as aggression or
withdrawal, interpersonal relationships and communication, and environmental
circumstances and experiences that elicit and shape emotion. Emotion
research can also include the study of licit and illicit psychoactive
substances that alter mood states, and conversely, the study of how emotional
and mood states can predispose to, or modulate the effects of, pain or
alcohol and psychoactive substances. This PA also encourages research on
emotional reactions in the context of the diagnosis and treatment of cancer,
and the study of emotion as it relates to this disease or increased risk of
this disease, including outcomes such as social relationships, health care
provider relationships, adherence and others. Although most emotion research
involves human populations, animal models of emotion are also valuable for
the investigation of particular aspects of emotion and its eliciting
contexts.
Recent years have shown the rapid expansion of concepts and methods for
studying emotion in all of its aspects. Outlined in this program
announcement are current needs that stem from these advances and that
constitute critical components of a comprehensive basic research strategy,
with the ultimate aim of fostering mental and physical health and the
understanding of human development and aging. Sample research questions are
provided for illustration, they are not intended to be exhaustive.
Basic Mechanisms of Emotion
The study of emotion involves measurements in a number of different response
systems (e.g., neural, physiological, subjective, expressive). To foster the
rapid and orderly accumulation of knowledge, it is important that multiple
system measurements be conducted whenever possible. Interactions of emotion
with cognition also constitute an important area of study. For example, more
detailed understanding is needed of the interplay between emotion and
cognition that can inform conceptualizations of disorders in which
impairments of both emotion and cognition are apparent (e.g., schizophrenia,
depression, alcohol and drug dependence, Alzheimer’s Disease, autism), as
well as provide data important for promoting emotional self-regulation and
understanding developmental processes. In addition, the interplay between
emotion and cognition may be studied in the context of risk perception and
decision-making as it applies to treatment and screening among cancer
patients or individuals at increased risk of cancer, and in the context of
financial and medical decision-making by older adults. Sample research
questions include the following:
o What are the relationships among behavioral, expressive, physiological,
and subjective aspects of emotion? What are the circumstances under which
these various systems act in concert, and what is the significance of various
patterns of desynchrony? What is the timing among the components and the
developmental course? What are the biological or psychological consequences
of the inhibition of one or more components?
o A number of different emotion theories posit some number of discrete
emotions. Other theories approach the domain as two, three or more
dimensions of emotional response. How are these two approaches related, and
can they be reconciled in a comprehensive theory of emotion?
o What are the continuities across, and distinctions among, the phenomena of
reflex, emotion, mood, temperament, emotional trait, and emotional disorder?
What social, psychological, and biological factors mediate their
interrelationships? How do these interrelationships change with age? How do
these phenomena interact in order to contribute to psychological adjustment,
normal psychological and biological development, treatment and screening
adherence, and quality of life among individuals with physical illness or
those at risk of illness?
o What are potential mechanisms by which sensation and perception influence
emotion? In turn, how are interactions between perception and emotion
modulated in the experience of pain, in learning and memory, and in cognitive
development?
o How do attention and memory act to sustain or interrupt emotional states?
In turn, how do emotional states serve to modulate or drive mechanisms of
attention and memory? How are interactions between attention, memory, and
emotion modulated or modified by alcohol and psychoactive drugs? How do
these interactions change over the course of development?
Emotional Processes in Mental, Substance Abuse, and Developmental Disorders,
and in Physical Disease
The study of emotional processes in disorders involves both similarities and
differences from research on basic mechanisms of emotion. Impairments of
emotion found in psychopathology and developmental disorders may differ in
either qualitative or quantitative ways from normal emotional processes.
Emotional reactions may interact with the course of disease processes to
alter the course of disorder. Examples of relevant issues include the
following:
o What are the continuities and discontinuities between normative emotional
processes (e.g., emotional development, expression, understanding, awareness,
communication) and emotional processes seen in psychopathology, developmental
disorders, alcohol or drug abuse, or resilience?
o To what extent can behavioral, expressive, physiological, and subjective
measures of emotion identify intent in individuals at risk for suicidal,
violent, or self-injurious behavior within the context of preventive
interventions?
o Do individual differences in emotional reactivity and regulation,
including responses to stress, produce differential vulnerabilities to mental
or developmental disorders, including alcohol and/or drug dependence?
Conversely, does alcohol/drug use or dependence produce changes in emotional
reactivity? How do stimuli associated with alcohol or drug use become
triggers of emotional and subjective states that may lead to relapse?
o Among cancer patients and people at increased risk for cancer, how do
individual differences in emotional processes relate to reports of fatigue,
return to work, adherence to treatment, nutritional recommendations, cancer
screening behaviors, health care provider patient relationships, and other
sequelae of the cancer diagnosis or known risk status? What are the
psychological and/or health consequences of the use of denial/repression
among cancer patients?
o How can individuals be trained to best identify emotions and mood states
that may represent a possible risk for relapse of physical or mental illness?
Does focusing on such emotions/moods help prevent relapse, or actually
increase risk for relapse?
o How do cognitive changes associated with late aging modify the expression
of emotion and its underlying processes in older individuals?
Individual Differences
Research is suggesting that individual differences in emotional responsivity
may mark specific vulnerabilities to mental disorder, including alcohol or
drug dependence, the detailed examination of these individual differences is
critical for understanding etiology and for designing prevention efforts.
In-depth study is needed of the determinants, consequences, and sequelae of
infant temperament. Research in adult personality variation also is
beginning to examine individual differences in emotional responsivity, with
some indications of connections to physiology. Sample research questions
include the following:
o What are the biological (including genetic) and experiential sources of
individual differences in emotional reactivity and regulation throughout
development? How do biological and experiential influences combine and
interact? How do these change with age?
o How do individual differences in emotionality relate to phenomena such as
activity level, attention, and cognitive processes? What are the neural
substrates that underlie relationships among such phenomena and how do these
relationships maintain or change over time?
o Among children with developmental and learning disabilities or childhood
illness, how are individual differences in emotional processes related to
functioning over time? How does the presence of developmental and/or
learning disabilities or other pediatric problems influence the development
of emotional regulation and reactivity over time?
o What biological, social, personality, and cognitive factors interact with
emotion-based individual differences to contribute to psychopathology and
drug use?
o How do emotions get attached to attitudes, stereotypes, and identity? How
do these influence illness and recovery?
Developmental Aspects
Data are accumulating rapidly in areas such as children"s understanding and
experience of emotions, and in emotional communications occurring between
parents and children beginning in the earliest weeks of life. The import of
findings related to the development of emotions would be well served by an
overarching theoretical framework specifying the ontogeny of emotion. Also,
the primary concentration to date on the early years of life needs to be
broadened to include focused attention on early and middle childhood,
adolescence, adulthood, and old age. Sample research questions include the
following:
o Are connections among various components of emotional response present at
birth? Do they change with age, particularly during periods of transition
(e.g., adolescence)? How do changes in bodily systems with age affect the
nature and intensity of emotional response and the interrelationships among
response systems? Do such changes predispose toward psychopathology in older
individuals?
o What are the determinants, age-specific characteristics, and consequences
of emotional attachments across the lifespan? What are the parallels among
attachment patterns in infancy, in childhood, in adolescence, in adulthood,
in old age?
o How do cognitive factors (e.g., intelligence, learning disabilities)
influence the development of emotional processes over the lifespan?
o What affective processes are particularly germane to coping with events in
the family life cycle (e.g., marriage, divorce, birth, transition to
parenthood, aging, retirement, grandparenting, dealing with death and
bereavement, coping with substance use of family members)?
o What are the developmental psychobiological contributions of stress and
other environmental influences on emotional development and expression?
o What is the role of emotion in brain development over the life course and
what are the relevant mechanisms? What is the role of endocrine and immune
systems and their neural control over the course of development and aging?
o Does prenatal exposure to alcohol or abused drugs or use of abused drugs
in adolescence affect emotional development? Conversely, are children with
disorders of emotional regulation more vulnerable to becoming drug dependent?
Social Aspects
The quality of interpersonal relationships can be a significant source of
both positive and negative emotions. Further, social relationships play a
substantial role in the modulation of emotional responses, however generated.
Social factors thus make a critical contribution to an understanding of the
risks for mental disorders and alcohol/drug dependence. In addition to the
need for further research on these interpersonal aspects of emotion, it is
very important to examine the macro-environmental processes (e.g., culture,
social structure, the media) that help to shape emotional development and
adjustment. Sample research questions include the following:
o How do cultural and socialization processes influence the experience and
expression of emotion? How do salient social factors and contexts (e.g.,
childcare settings, media, exposure to violence) in particular developmental
stages shape affective development and expression?
o What are the dynamics of emotional communications occurring within
families and other intimate groups and how do they relate to the development,
maintenance, or erosion of emotional bonds? How do variations in social
sharing of emotions lead to differences in psychopathology, therapeutic
approaches, and potential health outcomes? How are these patterns altered by
drug dependence? Among cancer patients and significant others, what are the
short- and long-term consequences of patterns of emotional communication on
social relationships and psychological adjustment?
o How do variations in parenting style and behaviors (e.g., teaching, limit-
setting) influence the development of affect regulation in children? How
does child neglect (resulting from psychopathology, alcohol or drug addiction
or other causes) influence emotional development in children?
o How does caregiver behavior influence affect regulation in persons with
mental disorders in late life, including Alzheimer’s Disease?
o How do the emotions involved with social relationships affect life in the
community for severely disordered individuals, and how do these emotions
interact with the characteristics of the disorder to affect its course?
o What role does the process of social comparison play in the emotional
response to cancer and to aging, what are some potential mechanisms
explaining the direction of the social comparison process across individuals,
and how might these processes be influenced by other social or non-social
mechanisms?
Biological Aspects
The study of emotion provides a valuable opportunity for examination of the
interplay between psychological, physiological, and neural processes, and
methods are increasingly becoming available for examining the neural
substrates of emotion. Sample research questions include the following:
o What are the bi-directional influences between emotional states or
emotional traits (e.g., temperament) and neurobiological, endocrine and
immune systems? Among cancer patients, how might these influences on biology
influence health status or treatment (side effects, ability to tolerate
treatment)?
o What are the neuroanatomical circuits and neurochemical processes involved
in emotional states and emotion-based individual differences? How do these
systems evolve over the lifespan? To what extent do these neural processes
overlap with those associated with psychopathology and substance use
disorders such as alcohol or drug addiction?
o How can neuroimaging and large-array electrophysiological techniques best
be used to study brain areas that are active during different emotional
states and in pain perception? What is the relationship of observed CNS
activity to other responses in emotion, including alcohol/drug-induced or
alcohol/drug withdrawal- or craving-induced changes in emotion?
o How does the aging process, either in association with age-associated
neurogenerative disease processes or without disease, affect the emotion-
based networks within the brain and those that interact with the endocrine
system?
Methodological Needs
Methods related to the study of emotion run the full range, from self-report
and interview procedures, to behavioral observations, and to measures of ANS
and CNS structure and function. Improvements are needed in ways that enhance
validity and efficiency of measurement without sacrificing richness and
detail. In research on physical illness such as cancer, also needed is
methodology that takes into account the reports of others in the patient’s
social and medical environment, and reports that are sensitive to the changes
in emotional responsiveness over time. Sample needs include the following:
o Most research on emotional expression concentrates on the face. Methods
also are needed to assess vocal, postural, and gestural components of
emotional expression. Further, measures of emotion need to be developed that
can be applied across cultures, cohorts, and species.
o Techniques of computer science, neural networks, and image processing need
to be applied to the task of producing valid and reliable judgments of facial
and other behavioral expressions of emotion.
o Expanded and improved neuroimaging techniques are needed to examine CNS
activity in emotional responding. Further research is needed on the
methodological and conceptual relationships among techniques with different
spatial and temporal resolution.
o Animal models need to be used to their fullest potential to examine social
and biological determinants and consequences of emotion.
o Advanced and ethically-guided human laboratory procedures for inducing
positive and negative emotional states are needed.
INCLUSION OF WOMEN AND MINORITIES IN RESEARCH INVOLVING HUMAN SUBJECTS
It is the policy of the NIH that women and members of minority groups and
their subpopulations must be included in all NIH supported biomedical and
behavioral research projects involving human subjects, unless a clear and
compelling rationale and justification is provided that inclusion is
inappropriate with respect to the health of the subjects or the purpose of
the research. This policy results from the NIH Revitalization Act of 1993
(Section 492B of Public Law 103-43).
All investigators proposing research involving human subjects should read the
"NIH Guidelines For Inclusion of Women and Minorities as Subjects in Clinical
Research," which have been published in the Federal Register of March 28,
1994 (FR 59 14508-14513) and in the NIH Guide for Grants and Contracts, Vol.
23, No. 11, March 18, 1994 available on the web at the following URL address:
http://grants.nih.gov/grants/guide/notice-files/not94-100.html
INCLUSION OF CHILDREN AS PARTICIPANTS IN RESEARCH INVOLVING HUMAN SUBJECTS
It is the policy of NIH that children (i.e., individuals under the age of 21)
must be included in all human subjects research, conducted or supported by
the NIH, unless there are scientific and ethical reasons not to include them.
This policy applies to all initial (Type 1) applications submitted for
receipt dates after October 1, 1998.
All investigators proposing research involving human subjects should read the
"NIH Policy and Guidelines on the Inclusion of Children as Participants in
Research Involving Human Subjects" that was published in the NIH Guide for
Grants and Contracts, March 6, 1998, and is available at the following URL
address: http://grants.nih.gov/grants/guide/notice-files/not98-024.html
Investigators also may obtain copies of these policies from the program staff
listed under INQUIRIES. Program staff may also provide additional relevant
information concerning the policy.
NOTE FOR APPLICATIONS FOCUSED ON AGING RESEARCH
Applications received in response to this PA may focus on scientific issues
related to aging. In describing the plan to recruit human subjects
investigators may cite a focus on aging as the justification for why children
will be excluded. In this regard, applicants may use Justification 1 from
the policy announcement, the research topic to be studied is irrelevant to
children.
SPECIAL NOTES:
Describe any requirements for the inclusion in the application of plans to
share data and indicate that reviewers will assess the adequacy of the
proposed plan. Include this in review criteria section
There is a limit of 10 pages in the preparation of Sections A-D of the
research Plan for this announcement.
URLS IN NIH GRANT APPLICATIONS OR APPENDICES
All applications and proposals for NIH funding must be self-contained within
specified page limitations. Unless otherwise specified in an NIH
solicitation, internet addresses (URLs) should not be used to provide
information necessary to the review because reviewers are under no obligation
to view the Internet sites. Reviewers are cautioned that their anonymity may
be compromised when they directly access an Internet site.
APPLICATION PROCEDURES
Applicants are strongly encouraged to contact the program contacts listed
under INQUIRIES with any questions regarding their proposed project and the
goals of this PA.
Applications are to be submitted on the grant application form PHS 398 (rev.
4/98) and will be accepted at the standard application deadlines as indicated
in the application kit. Application kits are available at most institutional
offices of sponsored research and from the Division of Extramural Outreach
and Information Resources, National Institutes of Health, 6701 Rockledge
Drive, MSC 7910, Bethesda, MD 20892-7910, telephone (301) 710-0267, Email:
GrantsInfo@nih.gov. Applications are also available on the World Wide Web
at: http://grants.nih.gov/grants/forms.htm.
The modular grant concept establishes specific modules in which direct costs
may be requested as well as a maximum level for requested budgets. Only
limited budgetary information is required under this approach. The
just-in-time concept allows applicants to submit certain information only
when there is a possibility for an award. It is anticipated that these
changes will reduce the administrative burden for the applicants, reviewers
and Institute staff. The research grant application form PHS 398 (rev. 4/98)
is to be used in applying for these grants, with the modifications noted
below.
BUDGET INSTRUCTIONS
Modular Grant applications will request direct costs in $25,000 modules, up
to a total direct cost request of $50,000 per year. The total direct costs
must be requested in accordance with the program guidelines and the
modifications made to the standard PHS 398 application instructions described
below:
PHS 398
o FACE PAGE: Items 7a and 7b should be completed, indicating Direct Costs (in
$25,000 increments up to a maximum of $50,000) and Total Costs [Modular Total
Direct plus Facilities and Administrative (F&A) costs] for the initial budget
period Items 8a and 8b should be completed indicating the Direct and Total
Costs for the entire proposed period of support.
o DETAILED BUDGET FOR THE INITIAL BUDGET PERIOD - Do not complete Form Page 4
of the PHS 398. It is not required and will not be accepted with the
application.
o BUDGET FOR THE ENTIRE PROPOSED PERIOD OF SUPPORT - Do not complete the
categorical budget table on Form Page 5 of the PHS 398. It is not required
and will not be accepted with the application.
o NARRATIVE BUDGET JUSTIFICATION - Prepare a Modular Grant Budget Narrative
page. (See http://grants.nih.gov/grants/funding/modular/modular.htm for
sample pages.) At the top of the page, enter the total direct costs
requested for each year. This is not a Form page.
o Under Personnel, List key project personnel, including their names, percent
of effort, and roles on the project. No individual salary information should
be provided. However, the applicant should use the NIH appropriation
language salary cap and the NIH policy for graduate student compensation in
developing the budget request.
o For Consortium/Contractual costs, provide an estimate of total costs
(direct plus facilities and administrative) for each year, each rounded to
the nearest $1,000. List the individuals/organizations with whom consortium
or contractual arrangements have been made, the percent effort of key
personnel, and the role on the project. Indicate whether the collaborating
institution is foreign or domestic. The total cost for a
consortium/contractual arrangement is included in the overall requested
modular direct cost amount. Include the Letter of Intent to establish a
consortium.
o Provide an additional narrative budget justification for any variation in
the number of modules requested.
o BIOGRAPHICAL SKETCH - The Biographical Sketch provides information used by
reviewers in the assessment of each individual"s qualifications for a
specific role in the proposed project, as well as to evaluate the overall
qualifications of the research team. A biographical sketch is required for
all key personnel, following the instructions below. No more than three
pages may be used for each person. A sample biographical sketch may be
viewed at: http://grants.nih.gov/grants/funding/modular/modular.htm
- Complete the educational block at the top of the form page,
- List position(s) and any honors,
- Provide information, including overall goals and responsibilities, on
research projects ongoing or completed during the last three years.
- List selected peer-reviewed publications, with full citations,
o CHECKLIST - This page should be completed and submitted with the
application. If the F&A rate agreement has been established, indicate the
type of agreement and the date. All appropriate exclusions must be applied
in the calculation of the F&A costs for the initial budget period and all
future budget years.
o The applicant should provide the name and phone number of the individual to
contact concerning fiscal and administrative issues if additional information
is necessary following the initial review.
Applications not conforming to these guidelines will be considered
unresponsive to this PA and will be returned without further review.
The title and number of the program announcement must be typed on line 2 of
the face page of the application form and the YES box must be marked.
Submit a signed, typewritten original of the application, including the
Checklist, and five signed photocopies in one package to:
CENTER FOR SCIENTIFIC REVIEW
NATIONAL INSTITUTES OF HEALTH
6701 ROCKLEDGE DRIVE, ROOM 1040, MSC 7710
BETHESDA, MD 20892-7710
BETHESDA, MD 20817 (for express/courier service)
REVIEW CONSIDERATIONS
Applications will be assigned on the basis of established PHS referral
guidelines. Applications will be evaluated for scientific and technical
merit by an appropriate scientific review group convened in accordance with
the standard NIH peer review procedures. As part of the initial merit
review, all applications will receive a written critique and undergo a
process in which only those applications deemed to have the highest
scientific merit, generally the top half of applications under review, will
be discussed and assigned a priority score.
The goals of NIH-supported research are to advance our understanding of
biological systems, improve the control of disease, and enhance health. In
the written comments reviewers will be asked to discuss the following aspects
of the application in order to judge the likelihood that the proposed
research will have a substantial impact on the pursuit of these goals. Each
of these criteria will be addressed and considered in assigning the overall
score, weighting them as appropriate for each application. Note that the
application does not need to be strong in all categories to be judged likely
to have major scientific impact and thus deserve a high priority score. For
example, an investigator may propose to carry out important work that by its
nature is not innovative but is essential to move a field forward.
(1) Significance: Does this study address an important problem? If the aims
of the application are achieved, how will scientific knowledge be advanced?
What will be the effect of these studies on the concepts or methods that
drive this field?
(2) Approach: Are the conceptual framework, design, methods, and analyses
adequately developed, well-integrated, and appropriate to the aims of the
project? Does the applicant acknowledge potential problem areas and consider
alternative tactics?
(3) Innovation: Does the project employ novel concepts, approaches or
methods? Are the aims original and innovative? Does the project challenge
existing paradigms or develop new methodologies or technologies?
(4) Investigator: Is the investigator appropriately trained and well suited
to carry out this work? Is the work proposed appropriate to the experience
level of the principal investigator and other researchers (if any)?
(5) Environment: Does the scientific environment in which the work will be
done contribute to the probability of success? Do the proposed experiments
take advantage of unique features of the scientific environment or employ
useful collaborative arrangements? Is there evidence of institutional
support?
In addition to the above criteria, in accordance with NIH policy, all
applications will also be reviewed with respect to the following:
o The adequacy of plans to include both genders, minorities and their
subgroups, and children as appropriate for the scientific goals of the
research. Plans for the recruitment and retention of subjects will also be
evaluated.
o The reasonableness of the proposed budget and duration in relation to the
proposed research
o The adequacy of the proposed protection for humans, animals or the
environment, to the extent they may be adversely affected by the project
proposed in the application.
o The adequacy of the proposed plan to share data, if appropriate.
AWARD CRITERIA
Applications will compete for available funds with all other recommended
applications assigned to the Institute. The following will be considered in
making funding decisions: Quality of the proposed project as determined by
peer review, availability of funds, and program priority.
INQUIRIES
Inquiries are encouraged. The opportunity to clarify any issues or questions
from potential applicants is welcome.
Direct inquiries regarding programmatic issues to:
Mary Ellen Oliveri, Ph.D.
Behavioral Science Research Branch
Division of Neuroscience and Basic Behavioral Science
National Institute of Mental Health
6001 Executive Blvd., Room 7220, MSC 9651
Bethesda, MD 20892-9651 (20852 for courier/express service)
Telephone: (301) 443-3942
FAX: (301) 443-9876
Email: moliveri@nih.gov
Jared B. Jobe, Ph.D.
Behavioral and Social Research Program
National Institute on Aging
Gateway Building, Room 533
7201 Wisconsin Avenue
Bethesda, MD 20892
Telephone: (301) 496-3137
FAX: (301) 402-0051
Email: Jared_Jobe@nih.gov
Ellen D. Witt, Ph.D.
Neuroscience and Behavioral Research Branch
National Institute on Alcohol Abuse and Alcoholism
6000 Executive Blvd., Suite 402, MSC 7003
Bethesda, MD 20892-7003
Telephone: (301) 443-6545
FAX: (301) 594-0673
Email: ewitt@willco.niaaa.nih.gov
Wendy Nelson, Ph.D.
Basic Biobehavioral Research Branch
Behavioral Research Program
National Cancer Institute
6130 Executive Blvd., MSC 7326
Executive Plaza North, Room 211
Bethesda, MD 20892-7326
Telephone: 301-435-4590
FAX: 301-435-7547
Email: wn14x@nih.gov
Margaret M. Feerick, Ph.D.
Child Development and Behavior Branch
National Institute of Child Health and Human Development
6100 Executive Blvd., Room 4B05, MSC 7510
Bethesda, MD 20892-7510
Telephone: (301) 435-6882
FAX: (301) 480-7773
Email: feerickm@mail.nih.gov
Jaylan S. Turkkan, Ph.D.
Behavioral Sciences Research Branch
National Institute on Drug Abuse
6001 Executive Blvd., Room 4282, MSC 9555
Bethesda, MD 20892-9555
Telephone: (301) 443-1263
FAX: (301) 594-6043
Email: jaylan@nih.gov
Direct inquiries regarding fiscal matters to:
Diana S. Trunnell
Grants Management Branch
National Institute of Mental Health
6001 Executive Boulevard, Room 6115, MSC 9605
Bethesda, MD 20892-9605
Telephone: (301) 443-2805
FAX: (301) 443-6885
Email: Diana_Trunnell@nih.gov
Joseph Ellis
Grants Management Office
National Institute on Aging
Gateway Building, Room 2N-212
7201 Wisconsin Avenue
Bethesda, MD 20892
Telephone: (301) 496-1472
FAX: (301) 402-3672
Email: ellisJ@exmur.nia.nih.gov
Judy Simons
Grants Management Branch
National Institute on Alcohol Abuse and Alcoholism
6000 Executive Blvd., Suite 504, MSC 7003
Bethesda, MD 20892-7003
Telephone: (301) 443-2434
FAX: (301) 443-3891
Email: js182a@nih.gov
Sara Stone
Grants Administration Branch
National Cancer Institute
6120 Executive Blvd., Room 243, MSC 7150
Bethesda, MD 20892-7150
Telephone: (301) 496-7249
FAX: (301) 496-8601
Email: stones@gab.nci.nih.gov
Doug Shawver
Grants Management Branch
National Institute of Child Health and Human Development
6100 Executive Boulevard, Room 8A01C, MSC 7510
Bethesda, MD 20892-7510
Telephone: (301) 496-1303
FAX: (301) 402-0915
Email: ds117g@nih.gov
Gary Fleming, J.D., M.A.
Grants Management Branch
National Institute on Drug Abuse
6001 Executive Boulevard, Room 3131, MSC 9541
Bethesda, MD 20892-9541
Telephone: (301) 443-6710
FAX: (301) 594-6849
Email: gf6s@nih.gov
AUTHORITY AND REGULATIONS
This program is described in the Catalog of Federal Domestic Assistance No.
93.242 (NIMH), 93.866 (NIA), 93.273 (NIAAA), 93.399(NCI), 93.865 (NICHD), and
93.279 (NIDA). Awards are made under authorization of the Public Health
Service Act, Title IV, Part A (Public Law 78-410, as amended by Public Law
99-158, 42 USC 241 and 285) and administered under PHS grants policies and
Federal Regulations 42 CFR 52 and 45 CFR Part 74. This program is not
subject to the intergovernmental review requirements of Executive Order 12372
or Health Systems Agency review.
The PHS strongly encourages all grant and contract recipients to provide a
smoke-free workplace and promote the non-use of all tobacco products. In
addition, Public Law 103-227, the Pro-Children Act of 1994, prohibits smoking
in certain facilities (or in some cases, and portion of a facility) in which
regular or routine education, library, day care, health care or early
childhood development services are provided to children. This is consistent
with the PHS mission to protect and advance the physical and mental health of
the American people.
Weekly TOC for this Announcement
NIH Funding Opportunities and Notices
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