Notice of Availability of Administrative Supplements for U.S. - Russia Collaborative HIV/AIDS Research

Notice Number: NOT-MH-12-001

Update: The following update relating to this announcement has been issued:

Key Dates
Release Date: October 12, 2011
Receipt Date:  January 15, 2012
Earliest Anticipated Start Date:  July 1, 2012

Issued by
National Institute of Mental Health (NIMH)
National Cancer Institute (NCI)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
National Institute of Allergy and Infectious Diseases (NIAID)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institute on Drug Abuse (NIDA)
Fogarty International Center (FIC)


The National Institutes of Health (NIH) supports international collaborative research and research training on HIV/AIDS and the exchange of scientific information by HIV/AIDS researchers around the world.  Scientific cooperation during the global HIV/AIDS pandemic has been strengthened between the United States (U.S.) and Russia.  Further cooperative research and capacity-building focused on HIV/AIDS would be of mutual benefit to the U.S. and Russia.  Therefore, the U.S. Secretary of Health and Human Services (HHS) supports the efforts of the NIH and the Russian Foundation for Basic Research (RFBR), to advance a new extramural research initiative.

A recent agreement between the NIH and the RFBR seeks to facilitate and support collaborative research partnerships (CRPs) among researchers and institutions in the U.S. and Russia via administrative supplements to existing NIH grants. Supplement requests may be derived from existing collaborations with an established history of interaction, or from new partnerships developed in response to this Notice provided the proposed research is within scope of the approved research aims of the parent grant.  The CRP must be based on an interactive relationship that maximizes the expertise of the individual U.S. and Russian research teams as well as the interaction between their parent institutions and granting agencies.  It is expected that these awards will develop and mature, leading to joint programs to pursue HIV/AIDS prevention strategies/interventions beyond the scope of the proposed supplement request.

This Notice is for administrative supplements for projects on HIV/AIDS research in the following priority areas: the basic science of HIV, microbicides, vaccines, behavioral and social science research, HIV-related co-morbidities, and genomics.

The number of administrative supplements awarded will be based on the merit of the administrative supplement requests received and the availability of funds.  The NIH and RFBR each plan to contribute funding for every project selected for funding.  Administrative supplement requests should not exceed 1 year and should request no more than $100,000 U.S. dollars (direct costs) or 25 percent of the Council-approved direct costs for the current budget year of the project (the lower of these amounts is the maximum allowable) from the NIH and up to 500,000 rubles from the RFBR. Applications that exceed these limits will not be accepted.

Research and Capacity-Building Objectives

The intent of this Notice is to foster collaborative research and capacity-building between current NIH grantees and Russian researchers working on HIV/AIDS.  Highest priority will be given to collaborative HIV projects that focus on the basic science of HIV (e.g., molecular biology and immunology), microbicides, vaccines, behavioral and social science research, infectious and non-infectious co-morbidities, and genomics. Specific co-morbidities of high interest include HIV/AIDS and cancer, tuberculosis (TB), and the intersection of injection and non-injection drug use, alcohol abuse, and mental health problems for individuals with HIV/AIDS.  Applicants are also encouraged to integrate these important domains- for example, a study to examine behavioral/adherence facilitators of microbicide use, or studies regarding the basic science or genomics of HIV in the context of vaccine development.

It is anticipated that administrative supplements supported through this program will result in sufficient preliminary data to allow the researchers to compete successfully for new NIH grants (e.g., R01, R21, R03).

Examples of topic areas that may be supported include, but are not limited to:

            Basic Science of HIV



            Behavioral and Social Science



Budget and Funding Information

In FY2012, it is anticipated that funds will be available for up to 15 administrative supplements to eligible NIH research grants. Individual administrative supplements requests should not exceed $100,000 direct costs and are limited to 25 percent of the Council-approved direct costs for the current budget year of the project (the lower of these amounts is the maximum allowable). Awards will be for 1 year and the existing grant must have at least 1 year remaining at the time that the supplement is submitted.

Administrative supplements for funded R01, R21, P01, U01, and P30 grants will be allowed. For Fogarty grantees, only AIDS International Training and Research Program (AITRP) projects (D43 grants) in Russia are eligible. Administrative supplement requests will also be accepted to supplement projects in the AIDS Malignancy Consortium, AIDS Cancer Specimen Resource, Centers for AIDS Research (CFAR), and the HIV/AIDS Clinical Trial Networks.

These funds cannot be used to conduct a clinical study requiring an investigational new drug including a phase 0, I, II, and/or III clinical trial, delivery of treatment, screening efforts to identify new therapeutic compounds for the cancers or sexually transmitted infections - associated with HIV acquisition.

IMPORTANT INFORMATION FOR APPLICANTS:  The research or capacity-building proposed by the NIH grantee in the collaboration must be within the original scientific scope of the NIH-supported grant project. Administrative supplements can be used to cover cost increases within the original scientific scope of the project, that result from making modifications to the project in order to take advantage of the proposed collaborations and activities that would increase the value of the project.  Applicants must provide evidence of the ongoing or proposed scientific collaborations necessary to support the proposed activities.

Administrative supplements may be submitted at any time before, but no later than 5:00PM in the applicant’s local time zone on January 15, 2012. Supplemental funds will be awarded by September 30, 2012.

Concurrent to the NIH administrative review, the RFBR will engage in an administrative review of all applications submitted to RFBR.  Funding decisions will be made jointly and will consider the research priorities of both countries.  Requests for supplements must comply with NIH policies for the inclusion of women, minorities, and children in research involving human subjects.

Before any funds can be expended for in-country research activities in a foreign country, the grantee institution must show evidence of compliance with U.S. and Russian regulations for the conduct of research involving human subjects.  Additional information can be found at the HHS Office for Human Research Protections website:

To be eligible the parent grant must be active, and the research proposed in the supplement must be accomplished within the current competitive segment.  The proposed supplement must be within the general scope of the peer-reviewed activities and aims approved within the parent grant.

Submitting an Administrative Supplement Request

Application Procedure

The U.S. scientists apply for funding in accordance with the NIH rules and the Russian scientists in accordance with the RFBR rules. In addition to submitting their NIH supplement request, the NIH applicant should collaborate with their Russia counterpart, and assist in the preparation of the Russian application that is submitted in parallel to the RFBR call for applications.  Applications are only eligible if both an NIH and RFBR application is submitted.

To apply for a supplement, applicants must submit the following:

  1. A cover letter citing this NOTICE, NOT-MH-12-001, requesting an administrative supplement, and containing the following information:
  1. Page 1 of the PHS398 grant application form, citing "Administrative Supplements for U.S.-Russia Collaborative HIV/AIDS Research” in Line 2.  Applicants must complete Page 1, and also include the signatures of the NIH grant Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) and authorized institutional budget office official from the NIH grant. Note that:
  1. An abstract (no more than one page)
  1. Research plan (no more than 6 pages) that includes:

Submission of Applications

An email mailbox has been set up for the receipt of Administrative supplement applications. Applications must be submitted as an e-mail attachment(s) in pdf format to:

Contact Brian Remortel at for issues related to electronic submission. 

To be considered for an administrative supplement, the request must be signed by the Authorized Organizational Representative/Signing Official (AOR/SO), and must describe the need for additional funding and the categorical costs.

Please note:  Applications should NOT be sent to the NIH Center for Scientific Review (CSR).

Requests must be submitted on the PHS398 Application forms available at: (font size and other formatting rules apply as designated in the instructions). 


Administrative supplement requests will be reviewed administratively by NIH Staff. Selection factors will include the following:


Inquiries and discussion of plans for responding to this Notice are strongly encouraged.

Direct inquiries regarding scientific, programmatic, and review matters to the appropriate Program Official listed below:

Geraldina Dominguez, Ph.D.
Office of HIV and AIDS Malignancy
National Cancer Institute (NCI)
31 Center Drive, Room 3A33, MSC 2440
Bethesda, MD 20852-2440
Telephone:  (301) 496-3204

NCI Basic Science Inquiries
Elizabeth Read-Connole, Ph.D.
Division of Cancer Biology
National Cancer Institute (NCI)
6130 Executive Boulevard. Suite 5016, MSC 7398
Bethesda, MD 20892-7398
Telephone:  (301) 496-6085

Kendall J. Bryant, Ph.D.
HIV/AIDS Coordinator
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
5635 Fishers Lane, Room 2062, MSC 9301
Bethesda, MD, 20892-9304
Telephone:  (301) 402-9389

Jon Warren, Ph.D.
Vaccine Research Program
Division of AIDS (VRP, DAIDS)
National Institute of Allergy and Infectious Diseases (NIAID)
6700-B Rockledge Drive, Room 5135
Bethesda, MD 20892-7628
Telephone: (301) 402-0633

Lynne M. Mofenson, M.D.
Center for Research for Mothers and Children
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
6100 Executive Boulevard, Room 4B11E, MSC 7510
Rockville, MD 20852-7510
Telephone:  (301) 435-6870

Katherine Davenny, PhD
Associate Director, AIDS Research Program
National Institute on Drug Abuse (NIDA)
6001 Executive Boulevard, Room 4215, MSC 9582
Bethesda, MD  20892-9582
Telephone:  (301) 443-2146

Christopher M. Gordon, PhD
Secondary HIV Prevention and Translational Research Branch
National Institute of Mental Health (NIMH)
6001 Executive Boulevard, Room 6212, 9619
Bethesda, MD 20892-9619
Telephone:  (301) 443-1613

Marya Levintova, Ph.D.
International Health Program Officer for Russia, Eurasia and Arctic Affairs
Division of International Relations
Fogarty International Center (FIC)
31 Center Drive, Room B2C11, MSC 2220
Bethesda, MD  20891-2220
Telephone:  (301) 496-4784

Direct inquiries regarding administrative and fiscal matters to:

Rita Sisco
Division of Extramural Activities
National Institute of Mental Health (NIMH)
Telephone: (301) 443-2805

Weekly TOC for this Announcement
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