Notice of Special Interest (NOSI): Administrative Supplements to Enhance Program Evaluation Capacity
Notice Number:

Key Dates

Release Date:


First Available Due Date:
March 15, 2022
Expiration Date:
March 16, 2023

Related Announcements

PA-20-272 - Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)

Issued by

National Institute of General Medical Sciences (NIGMS)


The National Institute of General Medical Sciences (NIGMS) announces the availability of funds for Administrative Supplements to institutions with NIGMS institutional training (T32, T34), institutional career development (K12), or certain research education program (R25, see below) awards. NIGMS institutional training, research education, and institutional career development programs must conduct ongoing evaluations to monitor the success of the training and mentoring activities and are expected to disseminate their outcomes to the broader community. The supplement awards will provide funds to enhance the institutional evaluation capacity to help meet these expectations for program evaluation. Plans for sustainability of the enhanced evaluation capacity beyond the funding period should be included in the supplement application. Applicants are strongly encouraged to discuss potential requests with their NIGMS Program Officer before submitting the supplement request.

Supplement awardees are expected to present an overview of the funded activities, the outcomes, and the progress in incorporating the activities into the ongoing program(s) at the meeting organized for Program Directors/Principal Investigators of NIGMS Training, Workforce Development, and Diversity programs.


Applicants must have an NIGMS-funded institutional training (T32, T34), institutional career development (K12), or certain research education program (R25, see below) award. Only R25 awards in the following programs (and associated funding opportunity announcements) are eligible for these supplements:

The parent award must be active when the supplement application is submitted (e.g. within the originally reviewed and approved project period) and may not be in a No-Cost Extension (NCE). Parent awards of applications submitted for the 2022 due date must have a project end date of May 31, 2023 or later. Parent awards of applications submitted for the 2023 due date must have a project end date of May 31, 2024 or later.

An applicant institution (normally identified by having a unique entity identifier such a DUNS number or NIH Institutional Profile File - IPF) may submit only one application in this topic area. For institutions with two or more NIGMS grants, it is expected that the Program Directors/Principal Investigators will cooperate to develop curricula and/or activities that are broadly applicable to individuals at their institution and that a single supplement request will be submitted through one of the eligible NIGMS awards.

Institutions that received a previous award for the enhancement of the institutional evaluation capacity through NOT-GM-20-020, NOT-GM-21-024, or NOT-GM-22-013 are not eligible.

Application and Submission Information

Applications for this initiative must be submitted using the following funding opportunity announcement or its subsequent reissued equivalent.

  • PA-20-272 -"Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)"

All instructions in the SF424 (R&R) Application Guide and PA-20-272 must be followed, with the following additions:

  • Application Due Date(s) March15, 2022 and March 15, 2023 by 5:00 PM local time of applicant organization.
  • For funding consideration, applicants must include the term NOT-GM-22-013 (without quotation marks) in the Agency Routing Identifier field (box 4b) of the SF424 R&R form. Applications without this information in box 4b will not be considered for this initiative.
  • Budget
    • Application budgets are limited to $80,000 direct costs (plus associated F&A costs) and must reflect the actual needs of the proposed project.
    • Funds from this supplement may be used for salary support of individuals designing, directing, and implementing the proposed activity. Funds may also be used for administrative staff salaries, consultant costs, equipment, faculty/staff travel, and other expenses directly related to the proposed activity.
    • Applicants may not use the funds to hire an external evaluator to conduct an evaluation of the program(s). The funds are intended to build evaluation capacity within the institution.
    • Funds from this supplement must be expended within one year of the supplement award issue date.
    • Applicants should note that the funds from this supplement cannot be used to support trainee stipends or tuition (T32 or T34), participant costs (R25), or scholar costs (K12).
  • Research Training Program Plan (limited to 3 pages): In the Program Plan attachment, include the summary or abstract of the funded parent award(s), and describe the following:
    • The need for the proposed funding. Describe how the proposed activities to enhance evaluation capacity will synergize with, but not duplicate, ongoing efforts in this area.
    • A description of the activities to enhance evaluation capacity and the potential impact on the institution.
    • How the effectiveness of the proposed activities will be assessed.
    • How the effective activities developed with this funding will be incorporated into the existing biomedical training program(s).
    • Plans for disseminating the activities and outcomes.
    • Plans for and institutional commitment to sustainability of the proposed activities.

Application Review Information

NIGMS staff will evaluate applications using the following criteria:

  • Is there a clearly identified need for the proposed activities?
  • Will the proposed activity have a broader impact on the training environment?
  • Is the plan feasible and likely to accomplish the goal of the supplement?
  • Is there an effective plan to incorporate and sustain the proposed activities into the ongoing training programs?
  • Are the plans to assess the outcomes likely to provide evidence of the effectiveness of the proposed activity?
  • Are the plans to disseminate the activities and outcomes feasible and likely to reach a broader audience?
  • Are the costs allowable and fully justified?


Please direct all inquiries to:
Marie Harton, Ph.D.
National Institute of General Medical Sciences (NIGMS)