NIA Caenorhabditis Interventions Testing Program (CITP) Announces Annual Call for Compounds to Test for Lifespan Extension in Caenorhabditis
Notice Number:

Key Dates

Release Date:

February 7, 2023

Related Announcements

NOT-AG-23-084 - NIA Caenorhabditis Interventions Testing Program (CITP) Announces Annual Call for Compounds to Test for Lifespan Extension in Caenorhabditis.

Reissue of NOT-AG-22-009 - NIA Caenorhabditis Intervention Testing Program (CITP) Announces A Call for Compounds to Test for Anti-Aging Activity in Caenorhabditis

Issued by

National Institute on Aging (NIA)


The National Institute on Aging (NIA) Caenorhabditis Interventions Testing Program (CITP) is soliciting proposals for compounds to enter the study in calendar years 2023-2024. This is not a funding opportunity announcement, but rather a solicitation of suggestions for compounds to be tested in the CITP.

The NIA CITP was established to test compounds purported to extend lifespan and/or delay the onset of disease and disability. The NIA CITP aims to identify pharmacological interventions that may moderate/alleviate health decline associated with aging in a robust manner using a genetically diverse set of Caenorhabditis strains. The CITP is comprised of four major components: three screening centers and a data coordinating center. The principal investigators at the screening centers are the following:

(1) Dr. Monica Driscoll Rutgers, The State University of New Jersey
(2) Dr. Gordon Lithgow Buck Institute
(3) Dr. Patrick Phillips University of Oregon

In addition to a screening center, Dr. Phillips heads the data coordinating center at the University of Oregon.

The CITP is a collaborative effort between the study sites and the sponsor who recommends interventions for study. The sponsor’s role is to provide the rationale for investigating the intervention(s) and to make recommendations on the dose, route, and timing for administration of the intervention, and propose assays and measurements to document the efficacy of the intervention. The sponsor will have access to all data developed from the study, will assist in analysis of the data, and will be a co-author on resulting publications. Sponsors proposals for specific interventions are reviewed by an Access Panel and prioritized by the CITP Steering Committee. All results of these studies will be published, and the data will be made publicly available. Any delays to publication will be reviewed by the CITP Steering Committee, whose decision will be final.

The deadline for receipt of proposals is May 1, 2023. Information on the NIA CITP and guidelines for proposal development are posted on the NIA’s CITP proposals webpage and the CITP website. Completed application forms should be submitted by email to Dr. Tiziana Cogliati at


Please direct all inquiries to:

Tiziana Cogliati, Ph.D.
National Institute on Aging
Division of Aging Biology
Telephone: 301-402-2178