NIH Exploratory/Developmental Research Grant Program (Parent R21)

Scope Note

The R21 grant mechanism is intended to encourage exploratory/developmental research by providing support for the early and conceptual stages of project development. The NIH has standardized the Exploratory/Developmental Grant (R21) application characteristics, requirements, preparation, and review procedures in order to accommodate investigator-initiated (unsolicited) grant applications. See the NIH Exploratory/Developmental Research Grant Award (R21) page for more information.
There is also a list of ICs that do not accept unsolicited R21 applications. Non-participating ICs might solicit other R21 applications using Requests for Applications (RFAs) or Program Announcements (PAs) to meet specific program needs. Information about such initiatives can be obtained in the NIH Guide for Grants and Contracts and by consulting with NIH staff. In some cases those announcements may specify different application characteristics, review criteria, and receipt dates.

PA-20-195

Release Date: May 8, 2020 
Expiration Date: May 8, 2024
Contacts and Special Interests

R21 Participating Institutes and Centers

R21 Non-Participating Institutes and Centers

  • NIH Institutes and Centers that DO NOT ACCEPT R21 applications in response to the Parent R21 Announcement but ONLY accept R21 applications in response to their specific funding opportunity announcements: FIC , NCATS, NCINHLBI, NIDDK, NIGMS, NIMH, NINDS, and ORIP.
NIH Institute/Center Scientific/Research Contact Scientific Research Areas of Interest Financial or Grants Management Contacts
National Center for Complementary and Integrative Health (NCCIH) Wen G. Chen, MMSc, PhD
Telephone: 301-451-3989
Email: chenw@mail.nih.gov
  
Shelley Carow
Telephone: 301-594-3788
Email: carows@mail.nih.gov
  
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Inquiries:
NICHD Referral Office
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Email: NICHDReferral@mail.nih.gov
The NICHD supports research in areas relevant to normal and abnormal human development, including contraception, fertilization, pregnancy, childbirth, prenatal and postnatal development; childhood development through adolescence; intellectual and developmental disabilities; and rehabilitation medicine.  https://www.nichd.nih.gov/grants-funding/opportunities-mechanisms/areas-research/Pages/default.aspx
Grant applications and project proposals must fall within the missions of the scientific branches of NICHD's Division of Extramural Research or its National Center for Medical Rehabilitation Research. Potential applicants are strongly encouraged to visit these pages for recent scientific advances and emerging public health topics.
If you have questions about projects within a specific research area, you may find an NICHD program officer.
 
Margaret Young
Grants Management Branch
Telephone: 301-642-4552
Email: margaret.young@nih.gov
National Eye Institute (NEI) Ellen Liberman, PhD
Telephone 301- 451-2020
Email: ellenliberman@nei.nih.gov
  
Karen Robinson Smith
Telephone: 301-451-2020
Email: Karen.Robinson.Smith@nei.nih.gov
  
National Human Genome Research Institute (NHGRI) Jennifer Troyer, Ph.D.
Telephone: 301-312-3276
Email: troyerj@mail.nih.gov
 
NHGRI will support the development of resources, approaches, and technologies that will accelerate genomic research on the structure of genomes, the biology of genomes, and the biology of disease; that will use genomics to advance the science of medicine; and that will incorporate genomics to improve the effectiveness of healthcare. NHGRI will also support genomic research in several cross-cutting areas, including the ethical, legal and societal implications of genomics and genetics research, bioinformatics, technology development, and research training and career development.
In general, NHGRI supports studies that provide generalizable methods and knowledge.  Applications for studies relevant only to a particular disease or organ system should be directed to the appropriate Institute or Center. NHGRI strongly encourages potential applicants to contact program staff in the early stages of developing your application. The contact information for the three scientific programs are:
 Division of Genome Science: https://www.genome.gov/27550609/division-of-genome-sciences-staff/
 Division of Genomic Medicine: https://www.genome.gov/27550610/division-of-genomic-medicine-staff/
 Division of Genomics and Society: https://www.genome.gov/27550080/division-of-genomics-and-society/
 
  
Deanna L. Ingersoll
Grants Administration Branch
Telephone: 301-435-7858
Email: Deanna.Ingersoll@nih.gov
  
National Institute on Aging (NIA) Dr. Sally Marik
Division of Extramural Activities
Telephone: 301- 594-2360
Email: sally.marik@nih.gov
  
Traci Lafferty
National Institute on Aging (NIA)
Telephone: 301-496-8987
Email:  laffertt@mail.nih.gov
National Institute on Alcohol Abuse and Alcoholism (NIAAA) Division of Epidemiology and Prevention Research
Gregory Bloss
Telephone: 301-443-3865
Email: gbloss@mail.nih.gov

Division of Medications Development Research
Joanne B. Fertig, Ph.D.
Telephone: 301-443-0635
Email:  jfertig@mail.nih.gov

Division of Metabolism and Health Effects
Svetlana Radaeva, Ph.D.
Telephone: 301-443-1189
Email: sradaeva@mail.nih.gov
  
Judy Fox
Telephone: 301-443-4704
Email: jfox@mail.nih.gov
  
National Institute of Allergy and Infectious Diseases (NIAID) Conrad Mallia, Ph.D.
Division of Allergy, Immunology, and Transplantation (DAIT)
Telephone: 240-627-3491
Email: cmallia@niaid.nih.gov​

Madelon Halula, PhD
Division of AIDS (DAIDS)
Telephone: 240-292-4843   
Email: mhalula@niaid.nih.gov

Suman Mukhopadhyay, Ph.D.
Division of Microbiology and Infectious Diseases (DMID)
Telephone:  (240) 627-3321
Email: mukhopadhyays@mail.nih.gov
  
Ann Devine
Telephone: 240-669-2988
Email: adevine@niaid.nih.gov
  
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) For information regarding NIAMS supported scientific areas/programs and contacts, please see: https://www.niams.nih.gov/grants-funding/supported-scientific-areas. Erik Edgerton
Telephone: 301- 594-7760
Email:  edgertont@mail.nih.gov
  
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

 
Inquiries:

NICHD Referral Office
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Email: NICHDReferral@mail.nih.gov

The NICHD supports research in areas relevant to normal and abnormal human development, including contraception, fertilization, pregnancy, childbirth, prenatal and postnatal development; childhood development through adolescence; intellectual and developmental disabilities; and rehabilitation medicine.  https://www.nichd.nih.gov/grants-funding/opportunities-mechanisms/areas-research/Pages/default.aspx

Grant applications and project proposals must fall within the missions of the scientific branches of NICHD's Division of Extramural Research or its National Center for Medical Rehabilitation Research. Potential applicants are strongly encouraged to visit these pages for recent scientific advances and emerging public health topics.

If you have questions about projects within a specific research area, you may find an NICHD program officer at https://www.nichd.nih.gov/grants-contracts/research-areas/priorities.

 

Bryan S. Clark, MBA
Grants Management Branch
Telephone: 301-402-0915
Email: clarkb1@mail.nih.gov
National Institute on Drug Abuse (NIDA) Yuki Lama, PhD
Phone: 301-443-4577
NIDAreferral@mail.nih.gov
Pam Fleming
Telephone: 301-480-1159
Email: pfleming@nida.nih.gov
  
National Institute on Deafness and Other Communication Disorders (NIDCD) Nancy L. Freeman, Ph.D.
Telephone: 301-402-3458
Email: FreemanN@mail.NIH.gov
 
The National Institute on Deafness and Other Communication Disorders (NIDCD) uses the Exploratory/Developmental Research Grant Award (R21) to support the development of novel ideas, technologies, or methodologies at an early stage of development which have the potential to break new ground or extend toward new directions or applications.
The NIDCD supports basic and clinical biomedical and behavioral research in the communication sciences of hearing, balance, smell, taste, voice, speech and language. The proposed research must be focused on one or more of these scientific mission areas.
 
https://www.nidcd.nih.gov/
  
Samantha Tempchin
Telephone: 301-435-1404
Email: tempchins@mail.nih.gov
National Institute of Dental and Craniofacial Research (NIDCR) Contact information can be found at: http://www.nidcr.nih.gov/Research/DER/ContactRA.htm
 
Integrative Biology and Infectious Diseases Branch
Amanda Melillo, Ph.D.
Phone: 301-594-7703 
Email: Amanda.melillo@nih.gov
 
Center for Clinical Research
Dena Fischer, DDS, MSD, MS
Telephone: 301-594-4876
Email: fischerdj@nidcr.nih.gov
 
Translational Genomics Research Branch
Zubaida Saifudeen, PhD.
Telephone: 301-827-3334
Email: zubaida.saifudeen@nih.gov
 
Behavioral and Social Science Research Branch
Melissa Riddle, Ph.D.
Telephone:  301-451-3888
Email: riddleme@nidcr.nih.gov

For current funding opportunities and contacts, see https://www.nidcr.nih.gov/grantsandfunding/FundingOpportunityAnnouncements/ByTopic.htm
  
Dede Rutberg, MBA
Chief Grants Management Officer
Telephone: 301-594-4798
Email:rutbergd@mail.nih.gov
National Institute of Environmental Health Sciences (NIEHS) The National Institute of Environmental Health Sciences (NIEHS) will accept investigator-initiated research projects using the R21 mechanism for all areas of environmental health science research; particularly those defined as NIEHS special emphasis areas. Details on these areas can be found at http://www.niehs.nih.gov/research/supported/programs/index.cfm.
To obtain more information about existing NIEHS program areas and their corresponding program administrators, see http://www.niehs.nih.gov/funding/grants/contacts.cfm 
  
Michelle Victalino
Telephone:  984-287-3336
Email:  victalinom@niehs.nih.gov
Bryann Benton
Telephone:  919-323-5577
Email: Bryann.Benton@nih.gov
  
National Institute on Minority Health and Health Disparities (NIMHD) The National Institute on Minority Health and Health Disparities (NIMHD) will accept investigator-initiated exploratory/developmental projects (R21) for all program areas supported by the Institute.
Please click on links below for descriptions of NIMHD’s main research interest areas and contact information for a scientific program contact in each area:

Community Health and Population Sciences
Clinical and Health Services Research
Integrative Biological and Behavioral Sciences
  
Priscilla Grant, JD
Telephone: 301-594-8412
Email:  pg38h@nih.gov
  
National Institute of Nursing Research (NINR) The National Institute of Nursing Research (NINR) will accept investigator-initiated R21 applications for exploratory/developmental projects in areas that are mission-relevant (http://www.ninr.nih.gov/AboutNINR/NINRMissionandStrategicPlan/). This includes potentially high-risk/high payoff projects in the early stages of development and projects having innovative scientific ideas. Please contact the NINR Program Director listed in the area of science in which you are interested. NINR Program Staff contacts may be found at: http://www.ninr.nih.gov/ResearchAndFunding/
DEA/OEP/AreasofscienceFile.htm
Brian Albertini
Telephone: 301-594-6869
Email: albertib@mail.nih.gov
National Library of Medicine (NLM)

Meryl Sufian, PhD
Chief Program Officer
Scientific contact for Public Health and Population Health Informatics, Social and Behavioral Science and Informatics, and Health Disparities and Health Equity
Phone: 301-496-4671
Email: sufianm@mail.nih.gov

Catherine Farrell, PhD
Program Officer
Scientific contact for Data Science (Computation/Curation, Information Management, Omics) and Bioinformatics
Telephone: 301-402-7081
Email: catherine.farrell@nih.gov 

Sung Sug (Sarah) Yoon, PhD
Program Officer
Scientific contact for Clinical Informatics (Electronic Health Records, Statistical Modeling, Social Determinants of Health) and Personal Health Informatics
Telephone: 301-496-7101
Email: sungsug.yoon@nih.gov 

Goutham Reddy, MD, MS
Program Officer
Scientific contact for Clinical Informatics (Health Care Delivery, Imaging, Knowledge Representation)
Phone: 301- 827-6728
Email: goutham.reddy@nih.gov 

Clayton Bingham, PhD
Program Officer
Scientific contact for Data Science (Imaging, Visualization, Statistical Models)
Telephone: 301-594-5929
Email: clayton.bingham@nih.gov 


The National Library of Medicine (NLM) will accept investigator-initiated R21 applications that explore new areas in its mission relevant areas, which include data science, healthcare/clinical informatics, public health informatics, translational informatics, bioinformatics, consumer health informatics and information sciences. NLM is particularly interested in highly innovative, high-risk/high impact biomedical informatics projects. The range and scope of NLM's research interests is described at http://www.nlm.nih.gov/ep/GrantExDev.html.
  

Andrea Culhane 
Chief Grants Management Officer
Telephone: 301-496-4221
Email: andrea.culhane@nih.gov 


This page last updated on: August 22, 2024
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