Contacts and Special Interests
Expiration Date: January 8, 2021
The R21 grant mechanism is intended to encourage exploratory/developmental research by providing support for the early and conceptual stages of project development. The NIH has standardized the Exploratory/Developmental Grant (R21) application characteristics, requirements, preparation, and review procedures in order to accommodate investigator-initiated (unsolicited) grant applications. See the NIH Exploratory/Developmental Research Grant Award (R21) page for more information.
R21 Clinical Trial Required Participating Institutes and Centers
- NIH Institutes and Centers that accept Investigator-Initiated R21 applications in response to the Parent R21 Clinical Trial Required Announcement - (PA-18-344): NHGRI, NIA, NIAAA, NIAID, NIAMS, NIDCD, NIDA, NIEHS, NIMH, NIMHD, NINR
- NIH Institutes and Centers that only accept Investigator-Initiated R21 applications proposing mechanistic clinical trials in response to the Parent R21 Clinical Trial Required Announcement PA-18-344): NIAMS, NIMH
- NIH Institutes and Centers that DO NOT ACCEPT applications in response to the Parent R21 Clinical Trial Required Announcement but ONLY accept R21 applications proposing clinical trial(s) in response to their specific funding opportunity announcements: : NCI, NEI, NHLBI, NIBIB, NICHD, NIDCR, NIDDK, NIGMS, NINDS, NLM, FIC, NCCIH, NCATS
Financial or Grants
Bettie J. Graham, Ph.D.
The National Human Genome Research Institute (NHGRI) will accept investigator-initiated exploratory/developmental projects (R21) for all program areas supported by the Institute. NHGRI uses the R21 mechanism for pilot projects or feasibility studies to develop new, and/or to significantly improve existing genomics and proteomics technologies and to encourage high risk/potential high payoff research. Potential applicants are encouraged to review the Institute's goals in its latest program planning document, "A Vision for the Future of Genomics Research," http://www.genome.gov/11007524.
Robin A. Barr, D. Phil.
The National Institute on Aging (NIA) will accept investigator-initiated exploratory/developmental projects (R21) for all program areas supported by the Institute.
For information regarding specific programmatic priorities, see Research Projects.
Division of Epidemiology and Prevention Research
Division of Medications Development Research
Division of Metabolism and Health Effects
Division of Neuroscience and Behavior
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) will accept investigator-initiated exploratory/developmental projects (R21) for all program areas supported by the Institute, particularly those defined as NIAAA special emphasis areas. The Institute's mission statement, extramural research program descriptions, list of special emphasis areas, active program announcements may be found at the NIAAA web site: http://www.niaaa.nih.gov.
The NIAAA R21 program provides limited support for exploring the feasibility of innovative or creative research questions within the research interests of the NIAAA. This includes basic and applied research on biochemical, physiological, genetic, and behavioral mechanisms leading to pathological drinking behavior; mechanisms of alcohol-induced organ damage, including fetal injury; and clinical, behavioral, and epidemiological approaches to more effective diagnosis, prevention, and treatment of alcoholism, alcohol abuse and alcohol-related problems. While applications may involve a wide variety of biomedical, behavioral, clinical, sociocultural, or other disciplines, relevance to the mission of the NIAAA must be clear.
To obtain more information about existing NIAAA program areas and the corresponding program administrators for R21 awards, please refer to the NIAAA extramural website.
Ellen Goldmuntz, M.D., Ph.D.
Mr. Martin Gutierrez
Shy Shorer, M.D.
For information regarding NIAMS supported scientific areas/programs and contacts, please see: https://www.niams.nih.gov/grants-funding/supported-scientific-areas.
Tracy Waldeck, Ph.D.
The National Institute on Drug Abuse (NIDA) The National Institute on Drug Abuse (NIDA) will accept investigator-initiated exploratory/developmental projects (R21) for all program areas supported by the Institute.
NIDA uses the R21 mechanism to provide support for projects in the early stages of developing or testing innovative ideas in any area relevant to the mission of the Institute. Since this mechanism is intended to enable an investigator to receive support for the early and conceptual stages of an innovative research question or approach, preliminary data specific to the proposed project are not expected. Novel scientific ideas, model systems, tools, agents, targets and technologies that have the potential to advance research in substantial ways and relevant to the mission of NIDA are appropriate for this mechanism. Long-term projects or projects designed to establish knowledge in a well-established area should not use the R21mechanism.
Nancy L. Freeman, Ph.D.
For a list of scientific staff, also see Staff Contacts.
The National Institute on Deafness and Other Communication Disorders (NIDCD) uses the Exploratory/Developmental Research Grant Award (R21) to support the development of novel ideas, technologies, or methodologies at an early stage of development which have the potential to break new ground or extend toward new directions or applications.
The NIDCD supports basic and clinical biomedical and behavioral research in the communication sciences of hearing, balance, smell, taste, voice, speech and language. The proposed research must be focused on one or more of these scientific mission areas.
Bonnie Joubert, Ph.D.
The National Institute of Environmental Health Sciences (NIEHS) will accept investigator-initiated research projects using the R21 mechanism for all areas of environmental health science research; particularly those defined as NIEHS special emphasis areas. Details on these areas can be found at http://www.niehs.nih.gov/research/supported/programs/index.cfm.
To obtain more information about existing NIEHS program areas and their corresponding program administrators, see http://www.niehs.nih.gov/funding/grants/contacts.cfm
NIMH Program Staff contacts or see Division web pages (below)
The National Institute of Mental Health (NIMH) will accept investigator-initiated exploratory/developmental projects (R21) for all program areas supported by the Institute:
Examples of the types of projects supported by NIMH through the R21 program include: pilot or feasibility studies; development of research methodology; high risk studies; development of new research technology; small-scale, self-contained projects; and analysis of existing data sets.
Rebecca Claycamp, M.S., C.R.A.
|National Institute on Minority Health and Health Disparities (NIMHD)
Rina Das, PhD
The National Institute on Minority Health and Health Disparities (NIMHD) will accept investigator-initiated exploratory/developmental projects (R21) for all program areas supported by the Institute. For further information on NIMHD investigator-initiated minority health and health disparities research, please see http://www.nimhd.nih.gov/programs/extra/iir.pdf.
Priscilla Grant, JD
The National Institute of Nursing Research (NINR) will accept investigator-initiated R21 applications for exploratory/developmental projects in areas that are mission-relevant (http://www.ninr.nih.gov/AboutNINR/NINRMissionandStrategicPlan/). This includes potentially high-risk/high payoff projects in the early stages of development and projects having innovative scientific ideas. Please contact the NINR Program Director listed in the area of science in which you are interested. NINR Program Staff contacts may be found at: http://www.ninr.nih.gov/ResearchAndFunding/