NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Required) (PA-18-344)

Contacts and Special Interests

Release Date: November 3, 2017
Expiration Date: January 8, 2021

Introduction

The R21 grant mechanism is intended to encourage exploratory/developmental research by providing support for the early and conceptual stages of project development. The NIH has standardized the Exploratory/Developmental Grant (R21) application characteristics, requirements, preparation, and review procedures in order to accommodate investigator-initiated (unsolicited) grant applications. See the NIH Exploratory/Developmental Research Grant Award (R21) page for more information.

R21 Clinical Trial Required Participating Institutes and Centers 

  • NIH Institutes and Centers that accept Investigator-Initiated R21 applications in response to the Parent R21 Clinical Trial Required Announcement  - (PA-18-344): NHGRI, NIA, NIAAA, NIAID, NIAMS, NIDCD, NIDA, NIEHS, NIMH, NIMHD, NINR
  • NIH Institutes and Centers that only accept Investigator-Initiated R21 applications proposing mechanistic clinical trials in response to the Parent R21 Clinical Trial Required Announcement PA-18-344):  NIAMS, NIMH
  • NIH Institutes and Centers that DO NOT ACCEPT applications in response to the Parent R21 Clinical Trial Required Announcement but ONLY accept R21 applications proposing clinical trial(s) in response to their specific funding opportunity announcements: NCI, NEI, NHLBI, NIBIB, NICHD, NIDCR, NIDDK, NIGMS, NINDS, NLM, FIC, NCCIH, NCATS
NIH Institute and Center Contacts and Scientific Research Areas of Interest
NIH Institute/Center

Scientific/Research Contact
Scientific Research Areas of Interest

Financial or Grants
Management Contact

National Human Genome Research Institute (NHGRI)

Bettie J. Graham, Ph.D.
Phone: 301-496-7531
FAX: 301-480-2770
Email: Bettie_graham@nih.gov

The National Human Genome Research Institute (NHGRI) will accept investigator-initiated exploratory/developmental projects (R21) for all program areas supported by the Institute. NHGRI uses the R21 mechanism for pilot projects or feasibility studies to develop new, and/or to significantly improve existing genomics and proteomics technologies and to encourage high risk/potential high payoff research. Potential applicants are encouraged to review the Institute's goals in its latest program planning document, "A Vision for the Future of Genomics Research," http://www.genome.gov/11007524.

Deanna L.Ingersoll
Grants Administration Branch
Phone: (301) 435-7858
E-mail:
Deanna.Ingersoll@mail.nih.gov

National Institute on Aging (NIA)

Robin A. Barr, D. Phil.
Phone: 301-496-9322
FAX: 301-402-2945
Email: BarrR@mail.nih.gov

The National Institute on Aging (NIA) will accept investigator-initiated exploratory/developmental projects (R21) for all program areas supported by the Institute.

For information regarding specific programmatic priorities, see Research Projects.

Linda Whipp
Phone: 301-496-1472
FAX: 301-402-3672
Email: whippL@mail.nih.gov

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Division of Epidemiology and Prevention Research
Gregory Bloss
Phone: 301-443-3865
FAX:301-443-8614
E-mail: gbloss@mail.nih.gov

Division of Medications Development Research 
Joanne B. Fertig, Ph.D.
Phone: 301-443-0635
FAX:301-443-8774
E-mail:  jfertig@mail.nih.gov

Division of Metabolism and Health Effects 
Dale Hereld, M.D., Ph.D.
Phone: 301-443-0912
FAX:301-594-0673
E-mail:  hereldd@mail.nih.gov

Division of Neuroscience and Behavior
Lindsey Grandison, Ph.D.
Phone 301-443-0606
FAX: 301-443-1650 
E-mail:  lgrandis@mail.nih.gov

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) will accept investigator-initiated exploratory/developmental projects (R21) for all program areas supported by the Institute, particularly those defined as NIAAA special emphasis areas.  The Institute's mission statement, extramural research program descriptions, list of special emphasis areas, active program announcements may be found at the NIAAA web site: http://www.niaaa.nih.gov.

The NIAAA R21 program provides limited support for exploring the feasibility of innovative or creative research questions within the research interests of the NIAAA. This includes basic and applied research on biochemical, physiological, genetic, and behavioral mechanisms leading to pathological drinking behavior; mechanisms of alcohol-induced organ damage, including fetal injury; and clinical, behavioral, and epidemiological approaches to more effective diagnosis, prevention, and treatment of alcoholism, alcohol abuse and alcohol-related problems. While applications may involve a wide variety of biomedical, behavioral, clinical, sociocultural, or other disciplines, relevance to the mission of the NIAAA must be clear.

To obtain more information about existing NIAAA program areas and the corresponding program administrators for R21 awards, please refer to the NIAAA extramural website.

Judy Fox
Phone: 301-443-4704
FAX: 301-443-3891
Email: jfox@mail.nih.gov

National Institute of Allergy and Infectious Diseases (NIAID)

Ellen Goldmuntz, M.D., Ph.D.
Division of Allergy, Immunology, and Transplantation (DAIT)
National Institute of Allergy and Infectious Diseases (NIAID)
Telephone: 240-627-3502
Email: egoldmuntz@niaid.nih.gov

Mr. Martin Gutierrez
Division of Acquired Immunodeficiency Syndrome (DAIDS)
National Institute of Allergy and Infectious Diseases (NIAID)
Telephone: 240-292-4844    
Email: mgutierrez@niaid.nih.gov

Shy Shorer, M.D.
Division of Microbiology and Infectious Diseases (DMID)
National Institute of Allergy and Infectious Diseases (NIAID)
Telephone: 240-627-3371
Email: ss932c@nih.gov

Laura Pone
National Institute of Allergy and Infectious Diseases (NIAID)
Telephone: 240-669-2951
Email: laura.pone@nih.gov

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Amanda Boyce, Ph.D.,
Phone: 301-594-5585
FAX: 301-480-1284
Email: boycea@mail.nih.gov​

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) will accept investigator-initiated exploratory/developmental projects (R21) for all program areas supported by the Institute.

For information regarding specific scientific programs and contacts, see http://www.niams.nih.gov/Funding/Funding_Opportunities/activity_codes.asp.

NIAMS accepts applications in response to PA-09-164 "NIH Exploratory/Developmental
Research Grant Program (Parent R21)"
 proposing studies related to arthritis, musculoskeletal or skin biology or diseases.

Potential applicants are strongly encouraged to discuss the suitability of the project for this program announcement with the NIAMS Program Director for that research topic area.  (See contacts by scientific area)

See NOT-AR-10-023 for additional information regarding NIAMS support for innovative research using R21 grants.

In making funding decisions on R21 applications, NIAMS will place a higher priority on projects that are:

  • Innovative, ground-breaking projects with potential for significant impact;            
  • Projects that involve novel technology or tool development, and have the potential to significantly accelerate research fields;
  • Projects that propose the novel application of methods, technologies, or conceptual approaches from outside biomedical science to a research problem in the NIAMS mission area.

Projects that will be considered a lower priority include:

  • Projects specifically to develop preliminary data for longer-term projects in a well established research area;
  • New investigator starter grants;
  • Pilot projects that do not exhibit a high degree of innovation.

Melinda B. Nelson 
Phone: 301-435-5278
FAX: 301-480-5450 
Email: mn23z@nih.gov

National Institute on Drug Abuse (NIDA)

Dr. Mark Swieter
Phone: 301-827-5844
Email: mswieter@nida.nih.gov

The National Institute on Drug Abuse (NIDA) The National Institute on Drug Abuse (NIDA) will accept investigator-initiated exploratory/developmental projects (R21) for all program areas supported by the Institute.

NIDA uses the R21 mechanism to provide support for projects in the early stages of developing or testing innovative ideas in any area relevant to the mission of the Institute. Since this mechanism is intended to enable an investigator to receive support for the early and conceptual stages of an innovative research question or approach, preliminary data specific to the proposed project are not expected.  Novel scientific ideas, model systems, tools, agents, targets and technologies that have the potential to advance research in substantial ways and relevant to the mission of NIDA are appropriate for this mechanism. Long-term projects or projects designed to establish knowledge in a well-established area should not use the R21mechanism.

Pam Fleming
Phone: 301-253-8729
FAX: 301-594-6849
Email: pfleming@nida.nih.gov

National Institute on Deafness and Other Communication Disorders (NIDCD)

Nancy L. Freeman, Ph.D.
Phone: 301-402-3458
FAX: 301- 402-6251
Email: FreemanN@mail.NIH.gov

For a list of scientific staff, also see Staff Contacts.

The National Institute on Deafness and Other Communication Disorders (NIDCD) uses the Exploratory/Developmental Research Grant Award (R21) to support the development of novel ideas, technologies, or methodologies at an early stage of development which have the potential to break new ground or extend toward new directions or applications.

The NIDCD supports basic and clinical biomedical and behavioral research in the communication sciences of hearing, balance, smell, taste, voice, speech and language. The proposed research must be focused on one or more of these scientific mission areas.

Christopher Myers
Phone:  301-435-0713
FAX: 301-402-1758
Email: myersc@mail.nih.gov

National Institute of Environmental Health Sciences (NIEHS)

Bonnie Joubert, Ph.D.
Telephone: 919-541-7667
Email: bonnie.joubert@nih.gov

https://www.niehs.nih.gov/funding/grants/announcements/index.cfm

The National Institute of Environmental Health Sciences (NIEHS) will accept investigator-initiated research projects using the R21 mechanism for all areas of environmental health science research; particularly those defined as NIEHS special emphasis areas. Details on these areas can be found at http://www.niehs.nih.gov/research/supported/programs/index.cfm.

To obtain more information about existing NIEHS program areas and their corresponding program administrators, see http://www.niehs.nih.gov/funding/grants/contacts.cfm

Bryann Benton
Telephone:  919-323-5577
Email:  Bryann.Benton@nih.gov

National Institute of Mental Health (NIMH)

NIMH Program Staff contacts or see Division web pages (below)

The National Institute of Mental Health (NIMH) will accept investigator-initiated exploratory/developmental projects (R21) for all program areas supported by the Institute:

Examples of the types of projects supported by NIMH through the R21 program include: pilot or feasibility studies; development of research methodology; high risk studies; development of new research technology; small-scale, self-contained projects; and analysis of existing data sets.

Rebecca Claycamp, M.S., C.R.A.
Phone: 301-443-2811
FAX: 301-480-1956
Email: rclaycam@mail.nih.gov

National Institute on Minority Health and Health Disparities (NIMHD)

Rina Das, PhD
Phone: 301-496-3996
Email: dasr2@mail.nih.gov

 

 

The National Institute on Minority Health and Health Disparities (NIMHD) will accept investigator-initiated exploratory/developmental projects (R21) for all program areas supported by the Institute. For further information on NIMHD investigator-initiated minority health and health disparities research, please see http://www.nimhd.nih.gov/programs/extra/iir.pdf.

Priscilla Grant, JD
Phone: 301-594-8412
Email:  pg38h@nih.gov

National Institute of Nursing Research (NINR)

The National Institute of Nursing Research (NINR) will accept investigator-initiated R21 applications for exploratory/developmental projects in areas that are mission-relevant (http://www.ninr.nih.gov/AboutNINR/NINRMissionandStrategicPlan/). This includes potentially high-risk/high payoff projects in the early stages of development and projects having innovative scientific ideas. Please contact the NINR Program Director listed in the area of science in which you are interested. NINR Program Staff contacts may be found at: http://www.ninr.nih.gov/ResearchAndFunding/
DEA/OEP/AreasofscienceFile.htm

Brian Albertini
Phone: 301-594-6869
FAX: 301-402-4502
Email: albertib@mail.nih.gov