Science-Driven Research Project Cooperative Agreement (UP1)

A cooperative agreement made to support a research project or research program in an area representing a PD/PI’s specific interest and competencies.

Purpose

Supports both standard and exploratory research projects. Exploratory projects include those that are in early and conceptual stages and may involve considerable risk that has the potential to lead to a breakthrough or major development in a field of biomedical, behavioral, or clinical research. 

Award Information

  • Funding Instrument: Cooperative Agreements
  • Funding Category: Research and Development
  • Budget Mechanism Code: RP - Research Projects

Application and Submission Information

Section IV. Application and Submission Information of a UP1 notice of funding opportunity (NOFO) describes the application options (exploratory, standard, and extended in cases when project periods greater than 5 years are allowed) and their associated project period, budget, and research strategy page limits.

Upon submission, applications with project periods up to 3 years will be identified as exploratory.

Due Dates

The Key Dates section of funding opportunities lists specific due dates. Many opportunities indicate Standard Due Dates apply.

Standard Application Due Dates (when applicable) Review and Award Cycles
New Renewal, Resubmission,
Revision as Allowed		 AIDS and AIDS Related
Grant Applications		 Scientific Merit Review Advisory Council
Review		 Earliest Start Date

Contact

  • Your organization's sponsored programs office or grants administrators can answer many internal and agency policy and process questions.
  • Understand NIH Staff Roles details how and when to find the right NIH contacts:
    • Before you apply, check your chosen funding opportunity for application submission, scientific/research, peer review, and financial/grants management contacts.  
    • After you apply, find NIH staff assignments in the Status module of eRA Commons.
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