Key Dates

Related Announcements

• April 25, 2024 - Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required). See NOFO PA-24-187.

Issued by

Office of The Director, National Institutes of Health (OD)

Purpose

The purpose of this notice is to correct language in the Funding Opportunity Purpose section of the NOFO PA-24-187, " Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required)" and extend the application deadline for Renewals/Resubmissions/Revisions (as allowed) from July 12, 2024, to August 12, 2024, to allow applicants time to prepare. The section regarding the Parent Announcement being for “basic science experimental studies involving humans” (i.e., BESH) was erroneously included in the Funding Opportunity Purpose description.  The NOFO is designated as Clinical Trial Required. Those wishing to submit under BESH should refer to NOFO PA-24-189 “Midcareer Investigator Award in Patient-Oriented Research (Parent K24 – Independent Basic Experimental Studies with Humans Required)”. Due to any possible confusion, we are extending the deadline for renewal/resubmission/revision (as allowed) applications to August 12, 2024.

Currently Reads:

Funding Opportunity Purpose

The purpose of the NIH Midcareer Investigator Award in Patient-Oriented Research (K24) is to provide support to mid-career health-professional doctorates for protected time to devote to patient-oriented research (POR) and to act as research mentors for junior clinical investigators pursuing POR research, such as clinical residents.

This Parent Announcement is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as “prospective basic science studies involving human participants.” These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should be submitted under this NOFO include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Applicants not planning an independent clinical trial or basic experimental study with humans or proposing to gain research experience in a clinical trial or basic experimental study with humans led by another investigator, must apply to the 'Independent Clinical Trial Not Allowed' companion NOFO. 

The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions. 

This Notice of Funding Opportunity (NOFO) is designed specifically for applicants proposing to serve as the lead investigator of an independent clinical trial, a clinical trial feasibility study, or a separate ancillary study to an existing trial, as part of their research and career development. Applicants not planning an independent clinical trial, or proposing to gain research experience in a clinical trial led by another investigator, must apply to companion NOFO (PA-24-188). 

The following table includes NIH standard due dates marked with an asterisk.

Modified to Read (changes shown in bold italics): 

Funding Opportunity Purpose 

The purpose of the NIH Midcareer Investigator Award in Patient-Oriented Research (K24) is to provide support to mid-career health-professional doctorates for protected time to devote to patient-oriented research (POR) and to act as research mentors for junior clinical investigators pursuing POR research, such as clinical residents. 

The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions. 

This Notice of Funding Opportunity (NOFO) is designed specifically for applicants proposing to serve as the lead investigator of an independent clinical trial, a clinical trial feasibility study, or a separate ancillary study to an existing trial, as part of their research and career development. Applicants not planning an independent clinical trial, or proposing to gain research experience in a clinical trial led by another investigator, must apply to companion NOFO (PA-24-188). 

The following table includes NIH standard due dates marked with an asterisk.

All other aspects of this NOFO remain unchanged.

Inquiries

Please direct all policy related inquiries to:

Division of Biomedical Research Workforce
Office of Extramural Research
Website: https://researchtraining.nih.gov
Email: NIHTrain@mail.nih.gov

For inquiries related to specific application instructions/guidance please see the Table of IC-Specific Information, Requirements and Staff Contacts website.