Release Date:  September 21, 1999 (see NOT-NS-03-020)

RFA:  NS-00-001

National Institute of Neurological Disorders and Stroke 
National Center for Research Resources

Letter of Intent Receipt Date:  November 30, 1999
Application Receipt Date:  March 10, 2000 


The National Institute of Neurological Disorders and Stroke(NINDS),in
collaboration with the National Center for Research Resources(NCRR)invites 
applications for Specialized Neuroscience Research Programs(SNRP)at Minority 
Institutions Awards. The purpose of this Request for Applications(RFA)is to 
augment and strengthen the research capabilities of faculty, students, and 
fellows at minority institutions by supporting the development of new, and/or 
the enhancement of ongoing, basic and clinical neuroscience research projects 
and programs.

The National Institutes of Health (NIH) recognizes that minority institutions 
are an integral component of our national biomedical research agenda.  
Therefore, the NIH is offering programmatic assistance for the development of 
the technology and resources that are necessary to conduct state-of-the-art 
neuroscience research.  The SNRP will help the awardee institutions prepare
the next generation of neuroscience investigators.  Beyond this, the SNRP will 
become regional resources that contribute to the NIH mission to find new 
knowledge that will improve the health of the American public.  This
competitive RFA is one way that the NIH identifies and supports
neuroscientists at eligible institutions to conduct and report the
meritorious, preliminary research that will foster successful competition for
traditional research project grants (e.g., R-series, P-series and/or
equivalent NSF grants) during the performance period of the award.


The Public Health Service (PHS) is committed to achieving the health promotion
and disease prevention objectives of "Healthy People 2000," a PHS-led national
activity for setting priority areas.  This RFA, "Specialized Neuroscience 
Research Programs at Minority Institutions", is related to the priority areas
of neurological disorders and stroke.  Potential applicants may obtain a copy
of "Healthy People 2000" (Full Report:  Stock No. 017-001-00474-0 or Summary 
Report: Stock No. 017-001-00473-1) through the Superintendent of Documents, 
Government Printing Office, Washington, DC 20402-9325 (Telephone
202-512-1800), or at http://odphp.osophs.dhhs.gov/pubs/hp2000.


Applications will only be accepted from domestic, public or private,
non-profit, academic institutions that offer Ph.D., M.D., and/or equivalent
health professional degrees, at which more than 50 percent of the students
enrolled are from cultural or racial minority groups.  Only one application
will be accepted per eligible institution. Each applicant institution must
identify a collaborating institution that can be a domestic Federal or
non-Federal, public or private, non-profit organization.  Because the awardee
will need continuous and substantial research collaborations to achieve the
objectives of this RFA, the collaborating organization must be in the U.S.,
its possessions, or its territories.

The principal investigator, who serves as SNRP Director, should be a U.S. 
citizen, permanent resident, or non-citizen national.  An award pursuant to
this RFA will not be made until and unless the institution appoints a Program 
Director who is a neuroscientist and has the professional skills needed to 
direct the Program.  (The administrative leadership skills, quality of 
independent neuroscience research, research productivity, and ability to
obtain and effectively use research support of the proposed Program Director
will be assessed.  See REVIEW CONSIDERATIONS).

Participating applicant investigators should have completed two or more years
of postdoctoral neuroscience research and must be full-time employees of the
applicant institution.  Participating collaborating investigators must be NIH
and/or NSF grantees who are currently supported by R-series, P-series and/or
equivalent NSF grant awards in the Neurosciences.  (See RESEARCH OBJECTIVES).


The Cooperative Agreement (U-series) award is the administrative mechanism for
supporting activities in which the NIH collaborates substantially in
scientific and/or programmatic matters with the awardee institution(s).  The
Specialized Center-Cooperative Agreement (U54) mechanism will be used to
support the SNRP award.  It is anticipated that collaborating neuroscientists
will benefit from a broader range of research resources and interdisciplinary
research approaches than are available at any one institution.  A SNRP award
will support research and research development activities within the scope of
the program priorities identified by the NINDS and NCRR.

The NIH will support and stimulate the activities of the awardee(s) by working
as a partner.  The NIH will not assume direction, take primary responsibility,
or in any other way dominate the activity.  The section TERMS AND CONDITIONS
contains detailed descriptions of the responsibilities, relationships, and
governance of the activities supported by the cooperative agreements for the
Specialized Neuroscience Research Programs at Minority Institutions.


The NINDS and NCRR plan to make up to three SNRP awards in Fiscal Year 2000. 
An applicant may request a project period of five or fewer years and a budget
for direct costs of up to $1,000,000 per year, excluding Facilities and
Administrative costs (F&A) on consortium arrangements.  Because the nature and
scope of the research proposed may vary, it is anticipated that the size of
each award will also vary.  Although the financial plans of the NINDS and NCRR
provide support for this program, awards pursuant to this RFA are contingent
upon the availability of funds and the receipt of applications of outstanding
scientific and technical merit.  At this time, it is not known if competing
renewal applications will be accepted and/or if this RFA will be reissued.



The NINDS and NCRR want to foster an improved health status of and eliminate
the health care disparity experienced by minority Americans.  Focused research
and research career development programs such as the Specialized Neuroscience 
Research Programs at Minority Institutions are used to achieve those
objectives.  Secondly, the NIH recognizes the contributions that minority
institutions can make to fulfilling the promise of the NIH research agenda are
unique and essential.  Therefore, the NIH has the responsibility to the Nation
to ensure that minority and other 'non-research-intensive' institutions can
develop the technology and other resources needed to conduct significant
neuroscience research.  Thirdly, the NIH, by means of the Specialized
Neuroscience Research Programs at Minority Institutions and other programs,
can foster the collaborative research affiliations needed to address
neuroscience research problems relevant to the communities and regions served
by the SNRP awardee institutions.

The Specialized Neuroscience Research Programs at Minority Institutions will
strive to meet the following programmatic goals:(1) to help minority
institutions develop state-of-the-art neuroscience research programs;(2) to
create more opportunities for researchers employed by minority institutions to
establish research collaborations and professional networks with NIH and/or
NSF grantees employed by research intensive institutions;(3)to increase the
role of ongoing research in maintaining a vigorous, stimulating academic and
intellectual milieu that will inspire and prepare students and fellows to
pursue research careers in neuroscience; and (4) to provide support for the
pilot research needed to show the skills and abilities of investigators by
obtaining the preliminary data and publications that can help ensure
successful competition for traditional research project grants during the
performance period of the award.

Research Areas

The NINDS is a leading supporter of scientific investigations into the causes,
prevention, diagnosis, and treatment of neurological disorders and stroke.  An
application for a Specialized Neuroscience Research Program at Minority 
Institutions could include proposals for basic and/or clinical research in the
following specific areas:

o  stroke and other cerebrovascular diseases and disorders;
o  episodic neurological states, such as epilepsy, chronobiology, circadian
   rhythms, and sleep;
o  demyelinating and immunologically-mediated disorders of the nervous system;
o  neuro-AIDS and other viral-associated diseases of the nervous system;
o  neuromuscular and peripheral nerve disorders;
o  fundamental neural processes, neuroprothesis and pain;
o  neurodegenerative diseases and disorders;
o  trauma and injury to the nervous system; and
o  neurogenetics, neuroendocrinology, and nervous system development.

The research plan of an application for a SNRP award must contain the 
description of up to three multidisciplinary, collaborative, research projects 
that will be mutually beneficial to participating investigators through 
coordinated, cooperative interactions.  Each of the proposed projects should 
effectively use the scientific and technical strengths of collaborating 
investigators to define a research plan appropriate to the requested duration  
that will advance scientific knowledge in the research areas identified above.

Description of Key Elements in an Application for a Specialized Neuroscience
Research Program Award

These are the key elements for the Specialized Neuroscience Research Program:

o  Selection and appointment of a SNRP Director who has had experience with
neuroscience research funding and research training;

o  Selection of up to three highly qualified applicant investigators to
propose and direct meritorious research projects suited to their neuroscience
research expertise.  These investigators are required to devote a minimum of
50 percent research effort to their respective projects;

o  Documentation of the nature and scope of the collaborative research
projects with NIH grantees from research intensive institutions. 
Collaborating investigators must devote a minimum of 20 percent research
effort to their respective projects;

o  Evidence that the senior leadership at the applicant institution has 
addressed issues such as tenure, promotion, research release time, and other 
personnel matters pertaining to the scientific success of the SNRP Director
and applicant investigators.  Documentation/evidence of institutional
commitment and the availability of technical resources and facilities for the
long-term support of the SNRP.  Features of the institutional environment that
are relevant to effective accomplishment of the overall neuroscience program
must be briefly described.  As appropriate, available resources (e.g.,
clinical and laboratory facilities, patient populations, geographic
distributions of space and personnel) and collaborative resources should be
described.  A letter of support from a senior institution official (e.g.,
President or Dean) should outline the commitment for resources and facilities
to sustain and support the neuroscience program throughout the period of
funding and beyond the performance period of this award;

o  The applicant must identify and outline plans for support staff (e.g.,
grants management, administrative, and technical) to ensure the timely
ordering of research supplies, equipment, and other resources essential to the
scientific productivity of the research award;

o  Eligible institutions must show evidence of an existing research
infrastructure that can support the neuroscience research program.  Previous
(past five years) and current research support used for neuroscience research
should be described.  The existing research infrastructure and needed
enhancements must be delineated;

o  Briefly describe how the proposed activities will enhance the scientific
capabilities of faculty, students and fellows in neuroscience, and strengthen 
the neuroscience curriculum; and

o  Define the chain of responsibility for decision making and administration,
beginning at the level of the institution's President and including all key 
staff (e.g., Sponsored Programs Administrator, Department Chair, and Dean).  
Describe the plans for day-to-day administration of the SNRP, including
program coordination, planning, and evaluation.  Describe the proposed
relationship of SNRP to existing programs and, in detail, how the SNRP
initiative will augment and strengthen the research infrastructure.


The awardee will work to establish research priorities within the approved
research scope of each SNRP award through discussions with the NINDS,
Director, Office of Special Programs in Neuroscience (NINDS-OSPN). The NINDS
reserves the right to include outside consultants/experts in these
discussions. After the awardee and the NINDS-OSPN have set the priorities, the
awardee will be responsible for conducting the research activities.  The
awardee and the NINDS-OSPN will interact in a cooperative manner throughout
the duration of the award to facilitate progress and resolve any problems that
may arise.  Other NIH program staff from the NCRR Director for Research
Infrastructure (NCRR-DRI) may participate in establishing research priorities
throughout the performance period of the SNRP award.


The following Terms of Award are in addition to, and not instead of, otherwise
applicable OMB administrative guidelines, HHS Grant Administration Regulations
at 45 CFR Part 74 and 92, and other HHS, PHS, and NIH grant administration
policies.  Cooperative Agreements are subject to the administrative
requirements outlined in pertinent OMB, HHS, PHS, and NIH guidelines, with
particular emphasis on HHS regulations at 42 CFR Part 52 and 45 CFR Part 74. 
Indirect costs are calculated and awarded for cooperative agreement awards the
same as for grants.

1.  The Awardee Rights and Responsibilities:

o  The awardee has primary authority and responsibility to define the
scientific objectives and approaches, to plan, conduct, analyze, and publish
results, interpretations, and conclusions of the studies;

o  The awardee has the primary responsibility for establishing effective and
substantial research collaborations with NIH and/or NSF grantees.  The scope
and nature of research on common protocols must be adequately documented and
must ensure participation, collaboration, and sharing of methods and data
among collaborating organizations;

o  The awardee has the primary responsibility for establishing an internal
advisory committee of the collaborating neuroscientists.  The committee will 
have the responsibility for directing and monitoring the progress of the 
research projects.  Beyond this, the committee must develop opportunities for 
information exchange, seminar presentations, and research training
opportunities for students and fellows;

o  The awardee has the primary responsibility for establishing an external
advisory committee of distinguished senior neuroscientists.  Annually, the
committee will assess the productivity of the SNRP, make recommendations for
the future direction of the SNRP initiative, and provide advice and guidance
about personnel matters and the allocation of resources to individual projects
and investigators.

The awardee will retain custody of and primary rights to the data and
intellectual property developed under the award, subject to current government
policies regarding rights of access as consistent with current HHS, PHS, and
NIH policies.  The NINDS reserves the right to negotiate additional awardee
terms and conditions based on recommendations from the Initial Review Group,
the National Advisory Research Resources Council and the National Advisory 
Neurological Disorders and Stroke Council.

2.  NINDS-OSPN and NCRR-DRI Staff Responsibilities:

The NINDS-OSPN and NCRR-DRI will have substantial scientific/programmatic
involvement during the award performance period by contributing to planning
and assessment activities, providing technical assistance, advice and
coordination beyond normal program stewardship for grants. (See INQUIRIES,

o  The NINDS-OSPN will have primary responsibility for stewardship of the
award and overall responsibility for monitoring the conduct, progress, and
fiscal management of the research program.  The NCRR-DRI will provide advice
and guidance as appropriate;

o  The NINDS-OSPN will help shape a comprehensive framework for the
development of the SNRP and provide technical advice and expertise regarding
scientific direction and program management.  The NCRR-DRI will provide advice
and guidance as appropriate;

o  The NINDS-OSPN and NCRR-DRI will help the applicant institution and SNRP
Director establish reasonable time lines to achieve the developmental goals of
the SNRP.  The NINDS-OSPN will facilitate interactions between the awardee and
collaborating investigators.  The NCRR-DRI will use programmatic authority 
within the Research Center for Minority Institutions (RCMI) Program to assist
in the sharing of research resources and infrastructure for SNRP awards at
RCMI-supported institutions;

o  The NINDS-OSPN and NCRR-DRI will reserve the authority to recommend
reductions in budget, withhold support, suspend and/or terminate the award if
technical performance falls below acceptable standards for quality and

o  The NINDS-OSPN and NCRR-DRI will actively participate as non-voting members
in all meetings of the external advisory committee during the performance
period of the award;

o  The NINDS-OSPN will have the authority to recommend additional research
endeavors within the approved research and negotiated budgets.  The NCRR-DRI 
will provide advice and guidance as appropriate; and

o  The NINDS-OSPN reserves the right to include selected extramural and
intramural staff as consultants/experts on scientific issues during the
performance period of the award.

3.  Arbitration

Any disagreements about scientific/programmatic matters (within the scope of
the award) between the awardee, the NINDS and NCRR may be brought to an
arbitration panel convened by the Director's of the co-sponsoring NIH
components. The decision of the arbitration panel, by majority vote, will be
binding.  The process to resolve programmatic differences described above in
no way affects the rights of a recipient of a cooperative agreement assistance
grant to appeal an adverse determination in accordance with PHS regulations at
42 CFR Part 50, Subpart D, and HHS regulations at 45 CFR Part 16.


It is the policy of the NIH that women and members of minority groups and
their sub-populations must be included in all NIH supported biomedical and
behavioral research projects involving human subjects, unless a clear and
compelling rationale and justification is provided that inclusion is
inappropriate with respect to the health of the subjects or the purpose of the
research.  Adequate plans to include both genders and minorities and their
subgroups as appropriate for the scientific goals of the research must be
included.  Plans for recruitment and retention of subjects will be evaluated. 
This policy results from the NIH Revitalization Act of 1993 (Section 492B of
Public Law 103-43).

All investigators proposing research involving human subjects should read the 
NIH Guidelines for Inclusion of Women and Minorities as Subjects in Clinical
Research, which have been published in the Federal Register of March 28, 1994 
(FR 59 14508-14513) and in the NIH Guide for Grants and Contracts, Volume 23, 
Number 11, March 18, 1994.  This information is available on the Internet at

Investigators also may obtain copies of the policy from the program staff
listed under INQUIRIES.  Program staff may also provide additional relevant
information concerning the policy.


It is the policy of NIH that children (i.e., individuals under the age of 21)
must be included in all human subjects research, conducted or supported by the
NIH, unless there is scientific or ethical reasons not to include them.  This
applies to all initial (Type 1) applications submitted for receipt dates after
October 1, 1998.

All investigators proposing research involving human subjects should read the
"NIH Policy and Guidelines on the inclusion of Children as Participants in
Research Involving Human Subjects" that was published in the NIH Guide for 
Grants and Contracts, March 6, 1998, and is available at the following URL 
address:  https://grants.nih.gov/grants/guide/notice-files/not98-024.html.


Prospective applicants are asked to submit, by November 30, 1999, a letter of 
intent that includes a descriptive title of the proposed research, the name, 
address, and telephone number of the principal investigator, the identities of 
other key personnel and participating institutions, and the number and title
of the RFA in response to which the application may be submitted.  Although a 
letter of intent is not required, is not binding, and does not enter into the 
review of a subsequent application, the information that it contains allows 
NINDS staff to estimate the potential review workload and avoid conflict of 
interest in the review.

The letter of intent is to be sent to:

Dr. Alfred W. Gordon
Director, Office of Special Programs in Neuroscience
National Institute of Neurological Disorders and Stroke
Neuroscience Center, Suite 2149
6001 Executive Boulevard
Bethesda, MD  20892-9535
Email:  ag38x@nih.gov


The research grant application form PHS 398 (rev. 4/98) is to be used in 
applying for these grants.  These forms are available at most institutional 
offices of sponsored research and may be obtained from the Division of 
Extramural Outreach and Information Resources, National Institutes of Health, 
6701 Rockledge Drive, MSC 7910, Bethesda, MD 20892-7910; telephone (301) 710-0267; Email: grantsinfo@nih.gov; and from the NIH program administrator listed 
under INQUIRIES.  They may also be downloaded from the Internet at 

An application for a SNRP award must include the following:

o  Competitive applications will develop new and/or strengthen existing
collaborative projects with NIH and or NSF grantees from research intensive
institutions.  Investigators must clearly define the nature and extent of the
research collaboration, such that they fully explain the necessary
administrative, fiscal, and scientific aspects in the application.

o  A research plan for up to five years that includes the proposed
organization and component functions of the SNRP.  The plan should demonstrate
the applicant's knowledge, ingenuity, practicality, and commitment to
developing a significant, productive, research program;

o  A description of and justification for the proposed individual research
projects and core service facilities.  Applicants are required to propose up
to three meritorious research projects, and must describe the nature and scope
of scientific research collaborations;

o  A description of the research and research training goals and capabilities
of the proposed SNRP.  The Program Director and NINDS-OSPN must establish a
time line for supported applicant investigators to prepare and submit
proposals for traditional research grant review during the performance period
of the SNRP award; and

o  A description of the infrastructure for conducting studies aimed at 
developing a nationally competitive neuroscience research program.

The RFA label, available in the PHS 398 (rev.4/98) application kit, must be
affixed to the bottom of the face page of the application.  Failure to use
this label could result in delayed processing of the application such that it
may not reach the review committee in time for review.  In addition, the RFA
number and title must be typed on line 2 of the face page of the application
form and the "YES" box must be marked.

The RFA label should indicate the RFA number.  

The sample RFA label available at:
https://grants.nih.gov/grants/funding/phs398/label-bk.pdf has been modified to
allow for this change.  Please not this is in pdf format.

Submit a signed, typewritten original of the application, including the
Checklist, and three signed photocopies, in one package to:

6701 ROCKLEDGE DRIVE, ROOM 1040 - MSC 7710
BETHESDA, MD  20892-7710
BETHESDA, MD  20817 (for express/courier service)

At the time of submission, two additional copies of the application must be
sent to:

Dr. Lillian Pubols
Scientific Review Branch
National Institute of Neurological Disorders and Stroke
Neuroscience Center, Room 3208
6001 Executive Boulevard
Bethesda, MD 20892


Letter of Intent Receipt Date:  November 30, 1999
Application Receipt Date:       March 10, 2000
Council Review:                 September 14, 2000
Earliest Award Date:            December 1, 2000

Applications must be received by March 10, 2000.  If an application is
received after that date, it will be returned to the applicant without review. 
The Center for Scientific Review (CSR) will not accept an application in 
response to this RFA that is essentially the same as one currently pending 
initial review, unless the applicant withdraws the pending application.  The
CSR will not accept any application that is essentially the same as one
already reviewed.  This does not preclude the submission of substantial
revisions of applications already reviewed, but such applications must include
an introduction addressing the previous critique.


Upon receipt, applications will be reviewed for completeness by CSR and
responsiveness by NINDS staff.  Applications that are incomplete and/or
non-responsive to this RFA, or exceed the maximum first year direct cost limit
of $1,000,000, excluding costs for consortium budgets, will be returned to the
applicant without further consideration.  A Special Emphasis Panel (SEP) 
convened by the NINDS will determine the scientific merit of each application 
compared to the other applications received in response to this RFA.  The
NINDS will withdraw from further competition those applications judged by the
SEP to be noncompetitive for an award and notify the applicant principal
investigator and applicant organization.

The review of the SNRP application is based not only on the traditional review
criteria for research projects, but also considers the feasibility and
potential for investigators to gain scientific independence.  The following
criteria will be used to evaluate the potential for productive collaborative
research, and the overall potential for enriching the academic and
intellectual milieu for doing research that will increase what is known about
healthy and disordered nervous systems.

o  The significance, approach, and innovation of the proposed research
projects and of the SNRP as a whole;

o  The scientific and administrative qualifications of the principal 
investigator to direct the SNRP;

o  The strengths of the applicant investigators and collaborating
neuroscientists, particularly the academic qualifications, neuroscience
research experience, expertise and research productivity;

o  Appropriateness and adequacy of the experimental approach and methodology
proposed to carry out the research, considering the applicant and collaborator
research backgrounds and their respective contributions in the development of 
the research proposal.  The application must have scientific merit, but unlike
a traditional research grant application, it must be evaluated in the context
of the developmental goals and feasibility of the study;

o  The nature, scope, and effectiveness of the plans for coordination and
cooperation among research project investigators;

o  Evaluate the facilities, resources, and environment of the applicant
institution (including existing relevant equipment, animal, and/or computer
resources, and departmental or interdepartmental cooperation);

o  Evidence of a detailed plan for career development of students and fellows
in neuroscience research and other neuroscience related health professions;

o  The specific research goals to be accomplished, the hypotheses to be
tested, and the likelihood that applicant investigators will produce the
publications and preliminary data to be competitive for a traditional research
grant during the performance period of the award;

o  Appropriateness of the proposed budget and duration, including the
justification for requested items in terms of the aims and methods of the
proposed research studies;

o  For research involving human subjects, adequacy of plans to include both
genders and minorities and their subgroups as appropriate for the scientific
goals of the research.  Plans for the recruitment and retention of subjects
will also be evaluated.  Reviewers should assess the age-appropriate inclusion
or exclusion of children in the research project and evaluate the plans for
conducting the research in accord with the NIH guidelines on the inclusion of
children as participants in research involving human subjects; and

o  The adequacy of the proposed plan for animal welfare and biohazard safety
in the research environment.


Funding decisions will be based on scientific and technical merit as
determined by the Initial Review Group, the National Advisory Research
Resources Council and the National Advisory Neurological Disorders and Stroke
Council, program balance, and the availability of funds.


Inquiries concerning this RFA are encouraged.  The opportunity to clarify any
issues or questions from potential applicants is welcome.

Direct inquiries regarding programmatic issues to:

Dr. Alfred W. Gordon
Director, Office of Special Programs in Neuroscience
National Institute of Neurological Disorders and Stroke
Neuroscience Center, Suite 2149
6001 Executive Boulevard
Bethesda, MD  20892-9535
Telephone:  (301) 496-3102
FAX:  (301) 594-5929
Email:  ag38x@nih.gov

Dr. Sidney A. McNairy, Jr.
Research Infrastructure
National Center for Research Resources
6705 Rockledge Drive, Room 6136
Bethesda, MD  20892
Telephone:  (301) 435-0788
FAX:  (301) 480-3770
Email:  sm68k@nih.gov

For information on budget and fiscal matters, contact:

Maurice Johnson
Grants Management Branch
National Institute of Neurological Disorders and Stroke
Neuroscience Center, Room 3254
6001 Executive Boulevard
Bethesda, MD  20892
Telephone:  (301) 496-7432
FAX:  (301) 402-0219
Email:  mj34w@nih.gov


This program is described in the Catalog of Federal Domestic Assistance No.
93.854 (Biological Basis Research in the Neurosciences).  Awards are made
under authorization of the Public Health Service Act, Title IV, Part A (Public
Law 78-410, as amended by Public Law 99-158, 42 USC 241 and 285) and
administered under PHS grants policies and Federal Regulation 42 CFR 52 and 45
CFR Part 74 and 92.  This program is not subject to the intergovernmental
review requirements of Executive Order 12372 or Health Systems Agency review.

The PHS strongly encourages all grant and contract recipients to provide a 
smoke-free workplace and promote the non-use of all tobacco products.  In 
addition, Public Law 103-227, the Pro-Children Act of 1994, prohibits smoking
in certain facilities (or in some cases, any portion of a facility) in which 
regular or routine education, library, day care, health care or early
childhood development services are provided to children.  This is consistent
with the PHS mission to protect and advance the physical and mental health of
the American people.

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