Release Date:  September 8, 1999

PA NUMBER:  PAS-99-165

National Institute on Alcohol Abuse and Alcoholism


The National Institute on Alcohol Abuse and Alcoholism (NIAAA) supports
research programs to advance understanding of the biological and behavioral
processes involved in the development, expression, and consequences of
alcoholism and other alcohol-related problems.  The Institute also supports
prevention, treatment, and health services research on alcohol abuse and
alcoholism.  A part of the NIAAA mission is the dissemination of new knowledge
acquired from alcohol research to diverse audiences including scientists;
educators; clinicians and other health and social service providers; patients
and their families; professionals within the criminal justice system; and the
general public. This Program Announcement (PA) identifies health education
activities that NIAAA will consider for award through Education Project Grants


The Public Health Service (PHS) is committed to achieving the health promotion
and disease prevention objectives of "Healthy People 2000," a PHS-led national
activity for setting priority areas.  This PA is related to the priority area
of alcohol abuse and alcoholism. Potential applicants may obtain a copy of
"Healthy People 2000" at


Applications may be submitted by domestic, non-profit organizations, public
and private, such as universities, colleges, hospitals, and laboratories,
units of State and local governments, and eligible agencies of the Federal
Government.  Racial/ethnic minority individuals, women, and persons with
disabilities are encouraged to apply as Principal Investigators.  Prior
consultation with NIAAA and written approval is required before the submission
of an application.

Small Business organizations are eligible to apply for alcohol science
education projects through the Small Business Innovation Research (SBIR) or
Small Business Technology Transfer (STTR) programs.  Information on the SBIR
and STTR programs is available at and from the NIAAA program
official listed under INQUIRIES.


This Program Announcement uses the National Institutes of Health (NIH)
Education Project Grant (R25) mechanism.  Responsibility for the planning,
direction and execution of the proposed project will be solely that of the
applicant.  The total project period for an application submitted in response
to this PA may not exceed three years.  Competing renewal applications may be
submitted for additional years beyond the initial project period.


It is anticipated that up to $750,000 in total costs for approximately three
to five R25 awards will be available annually, including both new and
continuation awards.  Given the diverse nature of activities supported under
this PA, the size of awards will vary.


Broad ranges of educational approaches are included within the context of this
PA.  Examples of anticipated activities include:

The development of courses and related materials designed to educate
scientists, educators, health and social service providers, and others, on
scientific advances in our knowledge of alcoholism and other alcohol-related

Educational activities directed to patients, their families, and the general
public which impart knowledge gained through research on alcohol-related
health issues, including those related to screening, treatment, and

Educational activities directed toward enhancing the knowledge of primary and
secondary school educators and/or students on alcohol-related problems.

Educational activities directed toward college students and college age
individuals, which apply knowledge gained through research in addressing the
particular alcohol issues confronting this age group.


It is the policy of the NIH that women and members of minority groups and
their subpopulations must be included in all NIH supported biomedical and
behavioral research projects involving human subjects, unless a clear and
compelling rationale and justification is provided that inclusion is
inappropriate with respect to the health of the subjects or the purpose of the
research. This policy results from the NIH Revitalization Act of 1993(Section
492B of Public Law 103-43).

All investigators proposing research involving human subjects should read the
"NIH Guidelines For Inclusion of Women and Minorities as Subjects in Clinical
Research," which have been published in the Federal Register of March 28, 1994
(FR 59 14508-14513) and in the NIH Guide for Grants and Contracts, Volume 23,
Number 11, March 18, 1994, available on the web at the following URL address:

Investigators may also obtain copies of the policy from the program staff
listed under INQUIRIES.


It is the policy of NIH that children (i.e., individuals under the age of 21)
must be included in all human subjects research, conducted or supported by the
NIH, unless there are scientific and ethical reasons not to include them. This
policy applies to all initial (Type 1) applications submitted for receipt
dates after October 1, 1998.

All investigators proposing research involving human subjects should read the
"NIH Policy and Guidelines on the Inclusion of Children as Participants in
Research Involving Human Subjects" that was published in the NIH Guide for
Grants and Contracts, March 6, 1998, and is available at the following URL


Prior written approval from NIAAA staff is required before an application will
be accepted.  A copy of this approval must be included as an appendix to the

Applications are to be submitted on the grant application form PHS 398 (rev.
4/98) and will be accepted at the standard application deadlines as indicated
in the application kit.  Applications kits are available at most institutional
offices of sponsored research and may be obtained from the Division of
Extramural Outreach and Information Resources, National Institutes of Health,
6701 Rockledge Drive, MSC 7910, Bethesda, MD 20892-7910, telephone 301/710-0267, email:  For those applicants with internet access,
the 398 kit may be found at  The PA title
and number must be typed on line 2 of the face page of the application form
and the YES box must be marked.  Page limits and limits on size of type are
strictly enforced.  Non-conforming applications will be returned without being

Submit a signed, typewritten original of the application, including the
Checklist, and five signed photocopies in one package to:

6701 ROCKLEDGE DRIVE, ROOM 1040 - MSC 7710
BETHESDA, MD  20892-7710
BETHESDA, MD  20817 (for express/courier service)


The goals of NIH-supported research are to advance our understanding of
biological systems, improve the control of disease, and enhance health.  In
the written comments, reviewers will be asked to discuss the following aspects
of the application in order to judge the likelihood that the proposed project
will have a substantial impact on the pursuit of these goals.  Each of these
criteria will be addressed and considered in assigning the overall score,
weighting them as appropriate for each application.  Note that the application
does not need to be strong in all categories to be judged likely to have major
impact and thus deserve a high priority score.

Significance: Does the project address an important alcohol-relevant problem
and a relevant target audience?  If the aims of the project are achieved will
a knowledge dissemination, education, or health objective be advanced?

Approach: Are the conceptual framework, design, methods, and analyses
adequately developed, well-integrated, and appropriate to the aims of the
project?  Does the applicant acknowledge potential problem areas and consider
alternative tactics?

Innovation: Does the project employ novel concepts, approaches, theories, or

Investigator: Are the project team members appropriately trained and well-
suited to carry out this work?  Has the research team committed the
appropriate time to accomplish project goals?

Environment: Does the environment in which the project will be conducted
contribute to the probability of success?  Does the proposed project take
advantage of the unique features of the environment or employ useful
collaborative arrangements?  Is there evidence of institutional support?

Budget: Is the requested budget and estimation of time to completion of the
project appropriate for the proposed effort?

In addition, plans for the recruitment and retention of subjects (participants
and/or the target audience) will be evaluated as well as the adequacy of plans
to include both genders, minorities and their subgroups, and children as
appropriate for the goals of the project.

The initial review group will also examine the provisions for the protection
of human subjects (participants and/or the target audience) and for the safety
of the project environment.


Applications recommended for approval by the National Advisory Council on
Alcohol Abuse and Alcoholism will be considered for funding on the basis of
the overall scientific and technical merit of the proposal as determined by
peer review, NIAAA programmatic needs and balance, and the availability of


Inquiries concerning Education Project Grants should be directed to:

Dorothea De Zafra
National Institute on Alcohol Abuse and Alcoholism
6000 Executive Boulevard MSC 7003
Bethesda, MD 20892-7003
Telephone: (301) 443-6516
FAX: (301) 443-7043

Direct inquiries regarding fiscal matters to:

Judy Simons
Grants Management Branch
National Institute on Alcohol Abuse and Alcoholism
6000 Executive Boulevard MSC 7003
Bethesda, MD 20892-7003
Telephone: (301) 443-2434
FAX: (301) 443-3891


This program is described in the Catalog of Federal Domestic Assistance, No.
93.273.  Awards are made under the authorization of the Public Health Service
Act, Sections 301 and 464H, and administered under the NIH grants policies and
Federal Regulations at Title 42 CFR Part 52 and 45 CFR Parts 74 and 92.  This
program is not subject to the intergovernmental review requirements of
Executive Order 12372 or Health Systems Agency Review.

The PHS strongly encourages all grant recipients to provide a smoke-free
workplace and promote the non-use of all tobacco products.  In addition,
Public Law 103-227, the Pro-Children Act of 1994, prohibits smoking in certain
facilities (or in some cases, any portion of a facility) in which regular or
routine education, library, day care, health care or early childhood
development services are provided to children.  This is consistent with the
PHS mission to protect and advance the physical and mental health of the
American people.

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