Notice Number: NOT-OD-20-097
Release Date: April 13, 2020
First Available Due Date: April 13, 2020
Expiration Date: April 01, 2021
Office of Behavioral and Social Sciences Research (OBSSR)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute on Aging (NIA)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of Environmental Health Sciences (NIEHS)
National Center for Complementary and Integrative Health (NCCIH)
National Cancer Institute (NCI)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) - New participating organization as of 04/17/2020 for due dates on/after 04/17/2020
National Institute of Nursing Research (NINR)- New participating organization as of 04/23/2020 for due dates on/after 04/23/2020
National Human Genome Research Institute (NHGRI) New participating organization as of 05/14/2020 for due dates on/after 05/14/2020
All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.
This Notice of Special Interest (NOSI) highlights the urgent need for social, behavioral, economic, health communication, and epidemiologic research relevant to the 2019 Novel Coronavirus (SARS-CoV-2) and COVID-19. This NOSI encourages urgent competitive supplements and administrative supplements to existing longitudinal studies that address key social and behavioral questions related to the COVID-19 pandemic, including adherence to and transmission mitigation from various containment and mitigation efforts; social, behavioral, and economic impacts from these containment and mitigation efforts; and downstream health impacts resulting from these social, behavioral, and economic impacts,including differences in risk and resiliency based on gender, race and ethnicity, socioeconomic status, and other social determinants of health.
As people across the United States and the rest of the world respond to the COVID-19 pandemic, the importance of behavioral and social factors in health and illness is being highlighted. Most of the current mitigation efforts are non-pharmacological interventions grounded in social and behavioral principles of prevention (e.g. risk communication, handwashing adherence, physical distancing, working from home, paid sick leave). The evidence base for many of these containment and mitigation efforts is based on limited research from prior influenza and SARS epidemics. However, we have minimal experience with a pandemic of this scope and the impacts of these extensive containment and mitigation efforts on transmission rates. Moreover, we have limited understanding of the impact on the personal and economic costs and downstream health and well-being impacts such as suicide and mental health exacerbations, substance abuse, adoption or reduction in healthy lifestyle behaviors (e.g tobacco use, dietary and physical activity regimens), and stress-based physical disorders.
To rapidly improve our understanding of the critical social and behavioral aspects of the COVID-19 pandemic, this NOSI encourages submission of applications for urgent competitive revisions or administrative supplements to active grants studying existing longitudinal cohorts, particularly those cohorts with considerable data relevant to COVID-19 social and behavioral factors prior and subsequent to the SAR-CoV-2 outbreak in various locations. These submissions are encouraged to consider four broad areas;
In addressing any of the four areas of interest it will be necessary to examine natural variation in individual, family, social, geographic, and structural levels of response, adherence, stigma, and impact using foreign and domestic opportunities, focusing on specific sectors of the population (including but not limited to gender, age group, socioeconomic status, geographic region, race/ethnicity, urban/rural, sexual orientation, gender identity). Investigators are strongly encouraged to include a range of groups and include medically underserved regions and vulnerable populations (e.g. pregnant women, the homeless, prison populations, people with disabilities, those in shelters or residential treatment settings) to the degree possible given the characteristics of their existing cohorts.
Applications are encouraged to leverage existing cohorts that present opportunities for quasi-experimental designs, natural experiments, interrupted time series analyses, computational and statistical modeling, and AI approaches. Applications that propose only descriptive pre-post associations are strongly discouraged. Findings from proposals submitted under this NOSI should generate more precise modeling parameters that could lead to increased accuracy and actionable predictions of use in this or future epidemics, examine underlying mechanisms of these interventions and their impacts, and/or leverage the staggered implementation of these interventions and their impacts in various locations (cities, counties, states, countries) for natural experiments controlling for appropriate confounds.
Responsive applications to this NOSI may include but are not limited to the following:
In addition to many areas of interest in the NOSI, NICHD has several additional interests.
NICHD has particular interest in COVID-19-related research on vulnerable populations falling within the NICHD scientific mission area, including pregnant and post-partum women, infants, children, and adolescents; individuals with physical and/or intellectual disabilities; and children who are homeless or in foster care.
NICHD also has particular interest in outcomes falling within its mission, including child abuse and neglect, intimate partner violence, learning outcomes, maternal, infant, child, and adolescent morbidity and mortality, changes in fertility and pregnancy outcomes, and access to health care, including reproductive health care.
Additional research topics of interest to NICHD that fall within the scope of this NOSI include, but are not limited to:
Application and Submission Information
Applications in response to this NOSI must be submitted using the following targeted funding opportunities or subsequent re-issued equivalents:
When developing applications in response to this NOSI, all instructions in the SF424 (R&R) Application Guide , PA-18-591, and PA-18-935 must be followed, with the following additions:
Applications nonresponsive to terms of this NOSI will be not be considered for the NOSI initiative.
Please direct all inquiries to:
Erica L. Spotts, PhD
Office of Behavioral and Social Sciences Research (OBSSR)